KEGG   ORTHOLOGY: K05080
Entry
K05080                      KO                                     

Name
GHR
Definition
growth hormone receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04935  Growth hormone synthesis, secretion and action
Disease
H00254  Growth hormone deficiency
H02037  Laron syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05080  GHR; growth hormone receptor
   04151 PI3K-Akt signaling pathway
    K05080  GHR; growth hormone receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05080  GHR; growth hormone receptor
   04060 Cytokine-cytokine receptor interaction
    K05080  GHR; growth hormone receptor
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    K05080  GHR; growth hormone receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05080  GHR; growth hormone receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  Prolactin receptor family
   K05080  GHR; growth hormone receptor
Other DBs
GO: 0004903
Genes
HSA: 2690(GHR)
PTR: 471560(GHR)
PPS: 100980367(GHR)
GGO: 101147704(GHR)
PON: 100451189(GHR)
NLE: 100600868(GHR)
MCC: 697986(GHR)
MCF: 102121279(GHR)
CSAB: 103215199(GHR)
RRO: 104667785(GHR)
RBB: 108526376(GHR)
CJC: 100399027(GHR)
SBQ: 101042350(GHR)
MMU: 14600(Ghr)
MPAH: 110328813(Ghr)
RNO: 25235(Ghr)
MUN: 110563813(Ghr)
CGE: 100763540(Ghr)
NGI: 103741346(Ghr)
HGL: 101716037(Ghr)
CCAN: 109697601(Ghr)
OCU: 100009325(GHR)
TUP: 102475227(GHR)
CFA: 403721(GHR)
VVP: 112933508(GHR)
AML: 100422780(GHR)
UMR: 103664663(GHR)
UAH: 113260944(GHR)
ORO: 101370443(GHR)
ELK: 111140951
FCA: 101093244(GHR)
PTG: 102952019(GHR)
PPAD: 109275863(GHR)
AJU: 106970898(GHR)
BTA: 280805(GHR)
BOM: 102268311(GHR)
BIU: 109574810(GHR)
BBUB: 102410211(GHR)
CHX: 100860790(GHR)
OAS: 443333(GHR)
SSC: 397488(GHR)
CFR: 102511929(GHR)
CDK: 105106998(GHR)
BACU: 103002001(GHR)
LVE: 103069416(GHR)
OOR: 101284890(GHR)
DLE: 111187036(GHR)
PCAD: 102996314(GHR)
ECB: 100053020(GHR)
EPZ: 103553842(GHR)
EAI: 106840032(GHR)
MYB: 102252226(GHR)
MYD: 102761733(GHR)
MNA: 107545625(GHR)
HAI: 109375245(GHR)
DRO: 112321076(GHR)
PALE: 102891638(GHR)
RAY: 107504486(GHR)
MJV: 108400493(GHR)
LAV: 100660760(GHR)
TMU: 101353524
MDO: 554180(GHR)
SHR: 100927655(GHR)
PCW: 110216101(GHR)
OAA: 100085538(GHR)
GGA: 408184(GHR)
MGP: 100546929
CJO: 107305958(GHR)
NMEL: 110389657(GHR)
APLA: 101800483(GHR)
ACYG: 106036341(GHR)
TGU: 100222341(GHR)
LSR: 110483764(GHR)
SCAN: 103821021(GHR)
GFR: 102034223(GHR)
FAB: 101813131(GHR)
PHI: 102101864(GHR)
PMAJ: 107216278(GHR)
CCAE: 111941452(GHR)
CCW: 104686635(GHR)
ETL: 114056056(GHR)
FPG: 101923548(GHR)
FCH: 102049860(GHR)
CLV: 102085422(GHR)
EGZ: 104121811(GHR)
NNI: 104009742 104020641(GHR)
ACUN: 113489859(GHR)
PADL: 103917288(GHR)
AAM: 106499487(GHR)
ASN: 102383050(GHR)
AMJ: 102559799(GHR)
PSS: 102446030(GHR)
CMY: 102936927(GHR)
CPIC: 101933105(GHR)
ACS: 100565883(ghr)
PVT: 110073909(GHR)
PBI: 103052977(GHR)
PMUR: 107288499(GHR)
TSR: 106549548
PMUA: 114606139(GHR)
GJA: 107121556(GHR)
XLA: 108707301(ghr.S) 398153(ghr.L)
XTR: 100493377(ghr)
NPR: 108791746(GHR)
DRE: 100001424(ghra)
IPU: 100304685(ghr) 108264905
PHYP: 113543166(ghr) 113546097
AMEX: 103029077(ghr) 103038295
EEE: 113578887 113588452(ghr)
TRU: 101070051(ghr2) 101072280(ghr1) 101079667
LCO: 104920655(ghr) 104928485
NCC: 104943312(ghr) 104947419
ONL: 100534400(ghr1) 100534534(ghr) 100690327
OLA: 100125809(ghr) 100144349(ghr) 101164128
XMA: 102218071(ghr) 102233795
CVG: 107093843(ghr) 107094674
CSEM: 103389092 103397680(ghr)
POV: 109639332(ghr) 109644124
HCQ: 109517519 109524008(ghr)
MALB: 109956524(ghr) 109973650
PKI: 111839225(ghr) 111851429
LCM: 102353866(GHR)
CMK: 103183867(ghr)
RTP: 109917113(ghr)
 » show all
Reference
  Authors
Grotzinger J
  Title
Molecular mechanisms of cytokine receptor activation.
  Journal
Biochim Biophys Acta 1592:215-23 (2002)
DOI:10.1016/S0167-4889(02)00316-6
Reference
PMID:2825030
  Authors
Leung DW, Spencer SA, Cachianes G, Hammonds RG, Collins C, Henzel WJ, Barnard R, Waters MJ, Wood WI
  Title
Growth hormone receptor and serum binding protein: purification, cloning and expression.
  Journal
Nature 330:537-43 (1987)
DOI:10.1038/330537a0
  Sequence
[hsa:2690]
LinkDB

KEGG   ORTHOLOGY: K05081
Entry
K05081                      KO                                     

Name
PRLR
Definition
prolactin receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04917  Prolactin signaling pathway
Disease
H01388  Hyperprolactinemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05081  PRLR; prolactin receptor
   04151 PI3K-Akt signaling pathway
    K05081  PRLR; prolactin receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05081  PRLR; prolactin receptor
   04060 Cytokine-cytokine receptor interaction
    K05081  PRLR; prolactin receptor
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05081  PRLR; prolactin receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05081  PRLR; prolactin receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  Prolactin receptor family
   K05081  PRLR; prolactin receptor
Other DBs
GO: 0004925
Genes
HSA: 5618(PRLR)
PTR: 461925(PRLR)
PPS: 100982237(PRLR)
GGO: 101147940(PRLR)
PON: 100294567(PRLR)
NLE: 100588784(PRLR)
MCC: 699369(PRLR)
MCF: 102139140(PRLR)
CSAB: 103215118(PRLR)
RRO: 104678745(PRLR)
RBB: 108543799(PRLR)
CJC: 100401704(PRLR)
SBQ: 101045141(PRLR)
MMU: 19116(Prlr)
MCAL: 110310217(Prlr)
MPAH: 110328981(Prlr)
RNO: 24684(Prlr)
MUN: 110566621(Prlr)
CGE: 100757415(Prlr)
NGI: 103735901(Prlr)
CCAN: 109690880(Prlr)
OCU: 100009046(PRLR)
TUP: 102500746(PRLR)
CFA: 479363(PRLR)
VVP: 112908600(PRLR)
AML: 100481840(PRLR)
UMR: 103664719(PRLR)
UAH: 113260881(PRLR)
ORO: 101375420(PRLR)
ELK: 111141177
FCA: 101101444(PRLR)
PTG: 102955301(PRLR)
PPAD: 109267715(PRLR)
AJU: 106978761(PRLR)
BTA: 281422(PRLR)
BOM: 102269313(PRLR)
BIU: 109574973(PRLR)
BBUB: 102415743(PRLR)
CHX: 100861318(PRLR)
SSC: 414916(PRLR)
CFR: 102516007(PRLR)
CDK: 105087006(PRLR)
BACU: 103010642(PRLR)
LVE: 103079910(PRLR)
OOR: 101275316(PRLR)
DLE: 111187584(PRLR)
PCAD: 102982565(PRLR)
ECB: 100053793(PRLR)
EPZ: 103545339(PRLR)
EAI: 106824748(PRLR)
MNA: 107546187(PRLR)
DRO: 112321146(PRLR)
PALE: 102890093(PRLR)
RAY: 107509701(PRLR)
MJV: 108405848(PRLR)
LAV: 100664727(PRLR)
TMU: 101347282
MDO: 100014991(PRLR)
SHR: 100915999(PRLR)
PCW: 110214629(PRLR)
OAA: 100078100(PRLR)
GGA: 395660(PRLR)
MGP: 100126248(PRLR)
CJO: 107305797(PRLR)
NMEL: 110389271(PRLR)
APLA: 101801910(PRLR)
ACYG: 106036342(PRLR)
ETL: 114066151(PRLR)
FPG: 101923331(PRLR)
FCH: 102047942(PRLR)
CLV: 102086225(PRLR)
EGZ: 104133847(PRLR)
NNI: 104014001(PRLR)
ACUN: 113489687(PRLR)
PADL: 103912213(PRLR)
AAM: 106499553(PRLR)
ASN: 102375493(PRLR)
AMJ: 102557950(PRLR)
CMY: 102931167(PRLR)
CPIC: 101938588(PRLR)
XLA: 373618(prlr.L) 373812(prlr.S)
XTR: 100491566(prlr)
DRE: 407651(prlra)
IPU: 108279093(prlr)
PHYP: 113535607(prlr)
AMEX: 103047565(prlr)
EEE: 113584562(prlr)
TRU: 101075300(prlr)
LCO: 104928231(prlr)
NCC: 104948052
MZE: 101477358(prlr)
ONL: 100534586(prlr)
OLA: 101169958(prlr)
XMA: 102217336(prlr)
XCO: 114149603(prlr)
PRET: 103473871(prlr)
CVG: 107085830(prlr)
NFU: 107374697(prlr)
KMR: 108231042(prlr)
ALIM: 106518181(prlr)
AOCE: 111587892
CSEM: 103390274(prlr)
POV: 109626004(prlr)
LCF: 108873988(prlr)
SDU: 111234713(prlr)
SLAL: 111664733(prlr)
HCQ: 109523624(prlr)
BPEC: 110160520(prlr)
MALB: 109960669(prlr)
SASA: 100136497(prlr)
OTW: 112259496(prlr)
SALP: 111981953(prlr)
ELS: 105007582(prlr)
SFM: 108932669(prlr)
PKI: 111852580(prlr)
BFO: 118431284
 » show all
Reference
  Authors
Grotzinger J
  Title
Molecular mechanisms of cytokine receptor activation.
  Journal
Biochim Biophys Acta 1592:215-23 (2002)
DOI:10.1016/S0167-4889(02)00316-6
Reference
  Authors
Trott JF, Hovey RC, Koduri S, Vonderhaar BK
  Title
Alternative splicing to exon 11 of human prolactin receptor gene results in multiple isoforms including a secreted prolactin-binding protein.
  Journal
J Mol Endocrinol 30:31-47 (2003)
DOI:10.1677/jme.0.0300031
  Sequence
[hsa:5618]
LinkDB

KEGG   ORTHOLOGY: K05057
Entry
K05057                      KO                                     

Name
OSMR
Definition
oncostatin M receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
Disease
H01217  Primary localized cutaneous amyloidosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05057  OSMR; oncostatin M receptor
   04151 PI3K-Akt signaling pathway
    K05057  OSMR; oncostatin M receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05057  OSMR; oncostatin M receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05057  OSMR; oncostatin M receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05057  OSMR; oncostatin M receptor
Other DBs
GO: 0004924
Genes
HSA: 9180(OSMR)
PTR: 461908(OSMR)
PPS: 100972785(OSMR)
GGO: 101129883(OSMR)
PON: 100440306(OSMR)
NLE: 100592022(OSMR)
MCC: 693569(OSMR)
MCF: 102135082(OSMR)
CSAB: 103215160(OSMR)
RRO: 104665752(OSMR)
RBB: 108515975(OSMR)
CJC: 100388286(OSMR)
SBQ: 101035348(OSMR)
MMU: 18414(Osmr)
MCAL: 110310557(Osmr)
MPAH: 110329042(Osmr)
RNO: 310132(Osmr)
CGE: 100772447(Osmr)
NGI: 103741367(Osmr)
HGL: 101696496(Osmr)
CCAN: 109688333(Osmr)
OCU: 100356631(OSMR)
TUP: 102487722(OSMR)
CFA: 489223(OSMR)
VVP: 112933532(OSMR)
AML: 100465053(OSMR)
UMR: 103664690(OSMR)
UAH: 113260912(OSMR)
ORO: 101377508(OSMR)
ELK: 111141176
FCA: 101096447(OSMR)
PTG: 102959455(OSMR)
PPAD: 109275827(OSMR)
AJU: 106970920(OSMR)
BTA: 514720(OSMR)
BOM: 102277729(OSMR)
BIU: 109574945(OSMR)
BBUB: 102393840(OSMR)
CHX: 102184003(OSMR)
OAS: 101105948(OSMR)
SSC: 100519398(OSMR)
CFR: 102508201(OSMR)
CDK: 105106827(OSMR)
BACU: 102999596(OSMR)
LVE: 103081180
DLE: 111187296(OSMR)
PCAD: 102975734(OSMR)
ECB: 100066819(OSMR)
EPZ: 103555269(OSMR)
EAI: 106824733(OSMR)
MYB: 102257110(OSMR)
MYD: 102767197(OSMR)
MNA: 107545740(OSMR)
HAI: 109387069(OSMR)
DRO: 112321081(OSMR)
PALE: 102884525(OSMR)
RAY: 107512429(OSMR)
MJV: 108401571(OSMR)
LAV: 100666724(OSMR)
TMU: 101348045
MDO: 100019300(OSMR)
SHR: 100934321(OSMR)
PCW: 110214934(OSMR)
OAA: 100076213(OSMR)
GGA: 427446(OSMR)
MGP: 104914848
CJO: 107305866
NMEL: 110389905
APLA: 101802348
ACYG: 106036327(OSMR)
TGU: 105760857(OSMR)
LSR: 110482633
SCAN: 103821014
GFR: 102038345(OSMR)
FAB: 101812471(OSMR)
PHI: 102108344(OSMR)
PMAJ: 107198170
CCAE: 111941103(OSMR)
CCW: 104686620(OSMR)
ETL: 114055020(OSMR)
FPG: 101914644(OSMR)
FCH: 102049736
CLV: 102086673
EGZ: 104133860(OSMR)
NNI: 104022972
ACUN: 113489568
PADL: 103921462(OSMR)
AAM: 106499543(OSMR)
ASN: 102381570(OSMR)
AMJ: 102558810(OSMR)
PSS: 102462890(OSMR)
CMY: 102931480(OSMR)
CPIC: 101934454(OSMR)
ACS: 103279691(osmr)
PVT: 110080084
PBI: 103053699(OSMR)
PMUR: 107288280(OSMR)
PMUA: 114606653
GJA: 107117956
XLA: 108707308(osmr.S) 108718407
XTR: 100485444(osmr)
NPR: 108785339(OSMR)
DRE: 100144562(osmr)
SRX: 107725162
CCAR: 109104256
AMEX: 103046850
EEE: 113568768
MZE: 101467260
ONL: 100689774
KMR: 108233634
 » show all
Reference
PMID:8999038
  Authors
Mosley B, De Imus C, Friend D, Boiani N, Thoma B, Park LS, Cosman D
  Title
Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.
  Journal
J Biol Chem 271:32635-43 (1996)
DOI:10.1074/jbc.271.51.32635
  Sequence
[hsa:9180]
Reference
  Authors
Grotzinger J
  Title
Molecular mechanisms of cytokine receptor activation.
  Journal
Biochim Biophys Acta 1592:215-23 (2002)
DOI:10.1016/S0167-4889(02)00316-6
LinkDB

KEGG   ORTHOLOGY: K05068
Entry
K05068                      KO                                     

Name
IL2RA, CD25
Definition
interleukin 2 receptor alpha
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04144  Endocytosis
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
Disease
H00091  T-B+Severe combined immunodeficiency
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04151 PI3K-Akt signaling pathway
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04658 Th1 and Th2 cell differentiation
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04659 Th17 cell differentiation
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   05162 Measles
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04090 CD molecules
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05068  IL2RA, CD25; interleukin 2 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K05068  CD25, IL2RA; interleukin 2 receptor, alpha
Other DBs
GO: 0004911
Genes
HSA: 3559(IL2RA)
PTR: 450884(IL2RA)
PPS: 100974407(IL2RA)
GGO: 101126210(IL2RA)
PON: 100440118(IL2RA)
NLE: 100582107(IL2RA)
MCC: 574300(IL2RA)
MCF: 102123605(IL2RA)
CSAB: 103237839(IL2RA)
RRO: 104664846(IL2RA)
RBB: 108529907(IL2RA)
CJC: 100412016(IL2RA)
SBQ: 101036589(IL2RA)
MMU: 16184(Il2ra)
MCAL: 110289347(Il2ra)
MPAH: 110334116(Il2ra)
RNO: 25704(Il2ra)
MUN: 110556899(Il2ra)
CGE: 100764797(Il2ra)
NGI: 103727306(Il2ra)
HGL: 101696651(Il2ra)
CCAN: 109690611(Il2ra)
TUP: 102503225(IL2RA)
CFA: 403870(IL2RA)
VVP: 112933655(IL2RA)
AML: 100466247(IL2RA)
UMR: 103676245(IL2RA)
UAH: 113241140(IL2RA)
ORO: 101378506(IL2RA)
ELK: 111158621
FCA: 493953(IL2RA)
PPAD: 109273771(IL2RA)
AJU: 106982335(IL2RA)
BTA: 281861(IL2RA)
BOM: 102274858(IL2RA)
BIU: 109567961(IL2RA)
BBUB: 102405003(IL2RA)
CHX: 102170059(IL2RA)
OAS: 443435(IL2RA)
SSC: 396814(IL2RA)
CFR: 102520401(IL2RA)
CDK: 105091372(IL2RA)
BACU: 102999308(IL2RA)
LVE: 103090256(IL2RA)
OOR: 101275717(IL2RA)
DLE: 111177977(IL2RA)
PCAD: 102974550(IL2RA)
ECB: 100070292(IL2RA)
EPZ: 103548896(IL2RA)
EAI: 106833795(IL2RA)
MYB: 102249529(IL2RA)
MYD: 102769642(IL2RA)
MNA: 107542420(IL2RA)
HAI: 109383783(IL2RA)
DRO: 112321040(IL2RA)
PALE: 102891511(IL2RA)
RAY: 107505982(IL2RA)
MJV: 108384839(IL2RA)
LAV: 100655361(IL2RA)
TMU: 101342095
MDO: 103093188(IL2RA)
SHR: 105750698(IL2RA)
PCW: 110198993(IL2RA)
OAA: 103165385(IL2RA)
GGA: 395294(IL2RA)
MGP: 100547769
CJO: 107315066
NMEL: 110392238(IL15RA)
APLA: 101789606
ACYG: 106038749(IL2RA)
TGU: 100222957
LSR: 110470954
SCAN: 103822517
FAB: 101805774
PHI: 102109566
PMAJ: 107204108
CCAE: 111923146
CCW: 104694531
ETL: 114067844(IL15RA)
FPG: 101919123
FCH: 102049741
CLV: 102090507
EGZ: 104134819
NNI: 104010490
ACUN: 113475946(IL15RA)
PADL: 103920842
AAM: 106487990
ASN: 102369874
AMJ: 106737583(IL2RA)
PSS: 102451419
CMY: 102937403(IL2RA)
CPIC: 101934224(IL2RA)
ACS: 103278808(il2ra)
PVT: 110088980
PMUR: 107294425(IL15RA)
PMUA: 114604914(IL2RA)
GJA: 107120141
LCM: 106704263
 » show all
Reference
PMID:6090949
  Authors
Nikaido T, Shimizu A, Ishida N, Sabe H, Teshigawara K, Maeda M, Uchiyama T, Yodoi J, Honjo T
  Title
Molecular cloning of cDNA encoding human interleukin-2 receptor.
  Journal
Nature 311:631-5 (1984)
DOI:10.1038/311631a0
  Sequence
[hsa:3559]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Knevel R, de Rooy DP, Zhernakova A, Grondal G, Krabben A, Steinsson K, Wijmenga C, Cavet G, Toes RE, Huizinga TW, Gregersen PK, van der Helm-van Mil AH
  Title
Association of variants in IL2RA with progression of joint destruction in rheumatoid arthritis.
  Journal
Arthritis Rheum 65:1684-93 (2013)
DOI:10.1002/art.37938
  Sequence
[hsa:3559]
LinkDB

KEGG   ORTHOLOGY: K05069
Entry
K05069                      KO                                     

Name
IL2RB, CD122
Definition
interleukin 2 receptor beta
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04144  Endocytosis
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04151 PI3K-Akt signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04659 Th17 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05202 Transcriptional misregulation in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05162 Measles
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04090 CD molecules
    K05069  IL2RB, CD122; interleukin 2 receptor beta
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05069  IL2RB, CD122; interleukin 2 receptor beta
CD molecules [BR:ko04090]
 Proteins
  K05069  CD122, IL2RB; interleukin 2 receptor, beta
Other DBs
GO: 0004911
Genes
HSA: 3560(IL2RB)
PTR: 470203(IL2RB)
PPS: 100992438(IL2RB)
GGO: 101139583(IL2RB)
PON: 100460977(IL2RB)
NLE: 100581366(IL2RB)
MCC: 696331(IL2RB)
MCF: 102138714(IL2RB)
CSAB: 103223268(IL2RB)
RRO: 104682498(IL2RB)
RBB: 108512733(IL2RB)
CJC: 100394910(IL2RB)
SBQ: 101030332(IL2RB)
MMU: 16185(Il2rb)
MCAL: 110310694(Il2rb)
MPAH: 110335025(Il2rb)
RNO: 25746(Il2rb)
MUN: 110548465(Il2rb)
NGI: 103748643(Il2rb)
HGL: 101726369(Il2rb)
CCAN: 109698250(Il2rb)
TUP: 102467660(IL2RB)
CFA: 403439(IL2RB)
VVP: 112929101(IL2RB)
AML: 100478292(IL2RB)
UMR: 103676409(IL2RB)
ORO: 101366322(IL2RB)
ELK: 111157559
FCA: 101092622(IL2RB)
PTG: 102965369(IL2RB)
PPAD: 109265527(IL2RB)
AJU: 106981084(IL2RB)
BTA: 104968644(IL2RB) 510185
BOM: 102284639(IL2RB) 106700824
BIU: 109559534(IL2RB)
BBUB: 102391873 102392192(IL2RB)
OAS: 101107088(IL2RB)
SSC: 100621776(IL2RB)
CFR: 102524470(IL2RB)
CDK: 105101578(IL2RB)
BACU: 103006990(IL2RB)
LVE: 103071005(IL2RB)
OOR: 101271954(IL2RB)
DLE: 111186349(IL2RB)
PCAD: 102995923(IL2RB)
ECB: 100069676(IL2RB)
EPZ: 103564462(IL2RB)
EAI: 106837581(IL2RB)
MYB: 102241115(IL2RB)
MYD: 102768408(IL2RB)
MNA: 107545294(IL2RB)
HAI: 109394467(IL2RB)
DRO: 112321925(IL2RB)
PALE: 102883396(IL2RB)
RAY: 107519288(IL2RB)
MJV: 108392662(IL2RB)
LAV: 100669139(IL2RB)
TMU: 101344371
MDO: 100025393(IL2RB)
SHR: 100913275(IL2RB)
PCW: 110205742(IL2RB)
OAA: 100092851(IL2RB)
GGA: 100859707(IL2RB)
MGP: 104911125(IL2RB)
CJO: 107313789(IL2RB)
NMEL: 110393218(IL2RB)
APLA: 101791719(IL2RB)
ACYG: 106035899(IL2RB)
TGU: 101232975(IL2RB)
LSR: 110483875(IL2RB)
SCAN: 103813230(IL2RB)
GFR: 102031500(IL2RB)
FAB: 101809303(IL2RB)
PHI: 102106386(IL2RB)
PMAJ: 107204849(IL2RB)
CCAE: 111935345(IL2RB)
CCW: 104696293(IL2RB)
ETL: 114055414(IL2RB)
FPG: 101915263(IL2RB)
FCH: 102058748(IL2RB)
CLV: 102091469(IL2RB)
EGZ: 104134213(IL2RB)
NNI: 104021675(IL2RB)
ACUN: 113475953(IL2RB)
PADL: 103924145(IL2RB)
AAM: 106488409(IL2RB)
ASN: 102376875(IL2RB)
AMJ: 102571730(IL2RB)
PSS: 102449512(IL2RB)
CMY: 102936500(IL2RB)
CPIC: 101932173(IL2RB)
ACS: 103278848(il2rb)
PVT: 110075925(IL2RB)
PBI: 112541087(IL2RB)
PMUR: 107302587(IL2RB)
TSR: 106555941(IL2RB)
PMUA: 114605576(IL2RB)
GJA: 107120056(IL2RB)
XTR: 101731938(il2rb)
DRE: 793920(il2rb)
IPU: 108272990 108273212(il2rb)
TRU: 101076872
LCO: 104936154(il2rb)
NCC: 104964346
OLA: 101165891 105354598(csf2rb)
PRET: 103468486
ALIM: 106520638 106522494(csf2rb)
AOCE: 111579444 111579883(csf2rb)
LCF: 108877635(il2rb)
HCQ: 109520288
MALB: 109972408(il2rb)
ELS: 105009012(il2rb) 105029657
LCM: 102367350
CMK: 103189779(il2rb)
RTP: 109914787(il2rb)
 » show all
Reference
PMID:2785715
  Authors
Hatakeyama M, Tsudo M, Minamoto S, Kono T, Doi T, Miyata T, Miyasaka M, Taniguchi T
  Title
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
  Journal
Science 244:551-6 (1989)
DOI:10.1126/science.2785715
  Sequence
[hsa:3560]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Bucheton B, Argiro L, Chevillard C, Marquet S, Kheir MM, Mergani A, El-Safi SH, Dessein AJ
  Title
Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis.
  Journal
Genes Immun 8:79-83 (2007)
DOI:10.1038/sj.gene.6364355
  Sequence
[hsa:3560]
LinkDB

KEGG   ORTHOLOGY: K05070
Entry
K05070                      KO                                     

Name
IL2RG, CD132
Definition
interleukin 2 receptor gamma
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04144  Endocytosis
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease
ko05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
H00093  Combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04151 PI3K-Akt signaling pathway
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04659 Th17 cell differentiation
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   05340 Primary immunodeficiency
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   05162 Measles
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
   04090 CD molecules
    K05070  IL2RG, CD132; interleukin 2 receptor gamma
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05070  IL2RG, CD132; interleukin 2 receptor gamma
CD molecules [BR:ko04090]
 Proteins
  K05070  CD132, IL2RG; interleukin 2 receptor, gamma (severe combined immunodeficiency)
Other DBs
GO: 0004911
Genes
HSA: 3561(IL2RG)
PTR: 101059843(IL2RG)
PPS: 100986679(IL2RG)
PON: 100454903(IL2RG)
NLE: 100585758(IL2RG)
MCC: 641338(IL2RG)
MCF: 102144912(IL2RG)
CSAB: 103232148(IL2RG)
RRO: 104656782(IL2RG)
RBB: 108532108(IL2RG)
CJC: 100388189(IL2RG)
SBQ: 101047979(IL2RG)
MMU: 16186(Il2rg)
MCAL: 110286942(Il2rg)
MPAH: 110313918(Il2rg)
RNO: 140924(Il2rg)
MUN: 110564656(Il2rg)
CGE: 100756284(Il2rg)
NGI: 103751955(Il2rg)
HGL: 101715243(Il2rg)
CCAN: 109673990(Il2rg)
OCU: 103351862(IL2RG)
TUP: 102476004(IL2RG)
CFA: 403851(IL2RG)
VVP: 112907637(IL2RG)
AML: 100468126(IL2RG)
UMR: 103682591(IL2RG)
UAH: 113245610(IL2RG)
ORO: 101374379(IL2RG)
ELK: 111161041
FCA: 101090239(IL2RG)
PTG: 102966580(IL2RG)
PPAD: 109254610(IL2RG)
AJU: 106982399(IL2RG)
BTA: 281862(IL2RG)
BOM: 102266681(IL2RG)
BIU: 109555190(IL2RG)
BBUB: 102402566(IL2RG)
CHX: 102169656(IL2RG)
OAS: 101103538(IL2RG)
SSC: 397156(IL2RG)
CDK: 105087982(IL2RG)
BACU: 103016442(IL2RG)
LVE: 103087530(IL2RG)
OOR: 101286718(IL2RG)
DLE: 111167807(IL2RG)
PCAD: 102979617(IL2RG)
ECB: 100055911(IL2RG)
EPZ: 103544610(IL2RG)
EAI: 106828880(IL2RG)
MYB: 102241164(IL2RG)
MYD: 102757155(IL2RG)
MNA: 107532895(IL2RG)
HAI: 109385585(IL2RG)
DRO: 112300079(IL2RG)
PALE: 102888070(IL2RG)
RAY: 107513773(IL2RG)
MJV: 108403309(IL2RG)
LAV: 100664834(IL2RG)
TMU: 101359472
MDO: 100619507(IL2RG)
SHR: 100929781(IL2RG)
PCW: 110201024(IL2RG)
OAA: 114812802(IL2RG)
GGA: 395199(IL2RG)
MGP: 104912104(IL2RG)
CJO: 107312576(IL2RG)
NMEL: 110403135(IL2RG)
APLA: 101794194(IL2RG)
ACYG: 106037383(IL2RG)
TGU: 100226174(IL2RG)
LSR: 110472683(IL2RG)
SCAN: 103824248(IL2RG)
GFR: 102043888(IL2RG)
FAB: 107603321(IL2RG)
PHI: 102112500(IL2RG)
PMAJ: 107203656(IL2RG)
CCAE: 111929372(IL2RG)
CCW: 104691748(IL2RG)
ETL: 114067449(IL2RG)
FPG: 101923008(IL2RG)
FCH: 102052025(IL2RG)
CLV: 102094834(IL2RG)
EGZ: 104124289(IL2RG)
NNI: 104012899(IL2RG)
ACUN: 113479902(IL2RG)
PADL: 103923348(IL2RG)
ASN: 102379602(IL2RG)
AMJ: 102575498(IL2RG)
PSS: 102443813(IL2RG)
CMY: 102933244(IL2RG)
CPIC: 101931356(IL2RG)
ACS: 103281066(il2rg)
PVT: 110080214(IL2RG)
PBI: 103061889(IL2RG)
PMUR: 107303211(IL2RG)
PMUA: 114589433(IL2RG)
GJA: 107108490(IL2RG)
XLA: 100036958(il2rg.L)
XTR: 100492995(il2rg)
NPR: 108800627(IL2RG)
DRE: 100144554(il2rgb) 796604(il2rga)
IPU: 108269358(il2rg) 108276805
TRU: 100190946(il2rg)
LCO: 104938889
NCC: 104967331
OLA: 101156347
XMA: 102230559
XCO: 114152754
PRET: 103475386
CVG: 107084171
NFU: 107386732
AOCE: 111573091
CSEM: 103395485(il2rg)
POV: 109635689
SDU: 111217233(il2rg)
SLAL: 111672069
HCQ: 109512452
MALB: 109960011
SALP: 111964368
LCM: 102356230(IL2RG)
 » show all
Reference
PMID:1631559
  Authors
Takeshita T, Asao H, Ohtani K, Ishii N, Kumaki S, Tanaka N, Munakata H, Nakamura M, Sugamura K
  Title
Cloning of the gamma chain of the human IL-2 receptor.
  Journal
Science 257:379-82 (1992)
DOI:10.1126/science.1631559
  Sequence
[hsa:3561]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Zhang Q, Wang HY, Liu X, Bhutani G, Kantekure K, Wasik M
  Title
IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK.
  Journal
Proc Natl Acad Sci U S A 108:11977-82 (2011)
DOI:10.1073/pnas.1100319108
  Sequence
[hsa:3561]
LinkDB

KEGG   ORTHOLOGY: K04737
Entry
K04737                      KO                                     

Name
IL3RA, CD123
Definition
interleukin 3 receptor alpha
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04210  Apoptosis
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
   04151 PI3K-Akt signaling pathway
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
   04090 CD molecules
    K04737  IL3RA, CD123; interleukin 3 receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL3 receptor family
   K04737  IL3RA, CD123; interleukin 3 receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K04737  CD123, IL3RA; interleukin 3 receptor, alpha (low affinity)
Other DBs
GO: 0004912
Genes
HSA: 3563(IL3RA)
PPS: 100967540(IL3RA)
PON: 100462256
MCC: 106995138(IL3RA) 114675718
MCF: 102138639
CSAB: 103247515(IL3RA)
RRO: 104663347(IL3RA)
RBB: 108520941(IL3RA)
CJC: 100405472(IL3RA)
SBQ: 101039092(IL3RA)
MMU: 16188(Il3ra)
MCAL: 110309476
MPAH: 110325021
RNO: 246144(Il3ra)
MUN: 110543786
CGE: 113838537
NGI: 103750125(Il3ra)
HGL: 101696721(Il3ra)
CCAN: 109688754(Il3ra)
OCU: 103345135(IL3RA)
TUP: 102476020(IL3RA)
CFA: 609293(IL3RA)
VVP: 112908954(IL3RA)
AML: 105238362(IL3RA)
UMR: 103666330(IL3RA)
UAH: 113240790(IL3RA)
ORO: 101383763(IL3RA)
ELK: 111157156
FCA: 105261394(IL3RA)
PPAD: 109256147(IL3RA)
AJU: 113597168(IL3RA)
BTA: 100299249(IL3RA)
BOM: 102279846
BBUB: 102399807(IL3RA)
CHX: 102178527(IL3RA)
OAS: 101113991(IL3RA)
CFR: 102512136(IL3RA)
CDK: 105103091(IL3RA)
BACU: 103005335(IL3RA)
LVE: 103083417(IL3RA)
OOR: 105748918(IL3RA)
DLE: 111168262(IL3RA)
PCAD: 102987302(IL3RA)
ECB: 106781070
MYD: 102758217
MNA: 107543962(IL3RA)
HAI: 109375560(IL3RA)
DRO: 112313317(IL3RA)
PALE: 102878242(IL3RA)
RAY: 107512530(IL3RA)
MJV: 108389002(IL3RA)
LAV: 104847204(IL3RA)
TMU: 101359308
MDO: 103094311(IL3RA)
SHR: 100917948(IL3RA) 105749995
PCW: 110212842(IL3RA)
 » show all
Reference
PMID:1833064
  Authors
Kitamura T, Sato N, Arai K, Miyajima A
  Title
Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors.
  Journal
Cell 66:1165-74 (1991)
DOI:10.1016/0092-8674(91)90039-2
  Sequence
[hsa:3563]
Reference
  Authors
Geijsen N, Koenderman L, Coffer PJ
  Title
Specificity in cytokine signal transduction: lessons learned from the IL-3/IL-5/GM-CSF receptor family.
  Journal
Cytokine Growth Factor Rev 12:19-25 (2001)
DOI:10.1016/S1359-6101(00)00019-8
Reference
PMID:8948019
  Authors
Hara T, Miyajima A
  Title
Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis.
  Journal
Stem Cells 14:605-18 (1996)
DOI:10.1002/stem.140605
  Sequence
[hsa:3563]
LinkDB

KEGG   ORTHOLOGY: K05055
Entry
K05055                      KO                                     

Name
IL6R, CD126
Definition
interleukin 6 receptor
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04066  HIF-1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04659  Th17 cell differentiation
ko04932  Non-alcoholic fatty liver disease
ko05163  Human cytomegalovirus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
   04066 HIF-1 signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
   04151 PI3K-Akt signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05055  IL6R, CD126; interleukin 6 receptor
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05055  IL6R, CD126; interleukin 6 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05055  IL6R, CD126; interleukin 6 receptor
   04659 Th17 cell differentiation
    K05055  IL6R, CD126; interleukin 6 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05055  IL6R, CD126; interleukin 6 receptor
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K05055  IL6R, CD126; interleukin 6 receptor
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K05055  IL6R, CD126; interleukin 6 receptor
   05163 Human cytomegalovirus infection
    K05055  IL6R, CD126; interleukin 6 receptor
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05055  IL6R, CD126; interleukin 6 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05055  IL6R, CD126; interleukin 6 receptor
   04090 CD molecules
    K05055  IL6R, CD126; interleukin 6 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05055  IL6R, CD126; interleukin 6 receptor
CD molecules [BR:ko04090]
 Proteins
  K05055  CD126, IL6R; interleukin 6 receptor
Other DBs
GO: 0004915
Genes
HSA: 3570(IL6R)
PTR: 469506(IL6R)
PPS: 100972031(IL6R)
GGO: 101130311(IL6R)
PON: 100459702(IL6R)
NLE: 100604063(IL6R)
MCC: 716690(IL6R)
MCF: 102116430(IL6R)
CSAB: 103223920(IL6R)
RRO: 104663493(IL6R)
RBB: 108526613(IL6R)
CJC: 100385661(IL6R)
SBQ: 101037958(IL6R)
MMU: 16194(Il6ra)
MCAL: 110291421(Il6r)
MPAH: 110320682(Il6r)
RNO: 24499(Il6r)
MUN: 110554248(Il6r)
CGE: 100750971(Il6r)
NGI: 103751364(Il6r)
HGL: 101704925(Il6r)
CCAN: 109688039(Il6r)
OCU: 100347752(IL6R)
TUP: 102492996(IL6R)
CFA: 612271(IL6R)
VVP: 112918888(IL6R)
AML: 100471277(IL6R)
UMR: 103668717(IL6R)
UAH: 113245310(IL6R)
ORO: 101368251(IL6R)
ELK: 111138952
FCA: 101085689(IL6R)
PTG: 102951407(IL6R)
PPAD: 109256188(IL6R)
AJU: 106987238(IL6R)
BTA: 507359(IL6R)
BOM: 102287439(IL6R)
BIU: 109554138(IL6R)
BBUB: 102411639(IL6R)
CHX: 102179824(IL6R)
OAS: 101103369(IL6R)
SSC: 399522(IL6R)
CFR: 102511771(IL6R)
CDK: 105089663(IL6R)
BACU: 103019388(IL6R)
LVE: 103078095(IL6R)
OOR: 101274728(IL6R)
DLE: 111167075(IL6R)
PCAD: 102994451(IL6R)
ECB: 102148787(IL6R)
EPZ: 103555416(IL6R)
EAI: 106828529(IL6R)
MYB: 102242151(IL6R)
MYD: 102757197(IL6R)
MNA: 107543721(IL6R)
HAI: 109373511(IL6R)
DRO: 112315493(IL6R)
PALE: 102878027(IL6R)
RAY: 107504721(IL6R) 107509418
MJV: 108393946(IL6R)
LAV: 100664198(IL6R)
TMU: 101356003
MDO: 100020561(IL6R)
SHR: 100924664(IL6R)
PCW: 110211977(IL6R)
OAA: 114808214(IL6R)
GGA: 693252(IL6R)
MGP: 104917170(IL6R)
CJO: 107324499(IL6R)
APLA: 113840022(IL6R)
TGU: 100231725(IL6R)
LSR: 110471522(IL6R)
SCAN: 103824053(IL6R)
GFR: 102038301(IL6R)
FAB: 101821627(IL6R)
PHI: 102105213(IL6R)
PMAJ: 107214583(IL6R)
CCAE: 111939461(IL6R)
CCW: 104683111(IL6R)
ETL: 114068440(IL6R)
FPG: 101910354(IL6R)
FCH: 102050149(IL6R)
AMJ: 102569548(IL6R)
CMY: 102929351(IL6R)
CPIC: 101947969(IL6R)
ACS: 103281452(il6r)
PVT: 110081055(IL6R)
PBI: 103050892(IL6R)
TSR: 106546959(IL6R)
PMUA: 114587119(IL6R)
GJA: 107117068(IL6R)
XTR: 100491081(il6r)
NPR: 108802740(IL6R)
DRE: 100135755(il6r)
IPU: 108266000(IL6R) 108266011
PHYP: 113542498(il6r)
AMEX: 103028913(il6r)
EEE: 113575234
TRU: 101069438
LCO: 104934469
NCC: 104959175
MZE: 101486162
ONL: 100702023
OLA: 101173653
XMA: 102233430
XCO: 114142297
PRET: 103478148
KMR: 108241027
ALIM: 106518420
AOCE: 111562998
CSEM: 103388203
POV: 109633010
LCF: 108885967
SDU: 111237206
HCQ: 109529023
BPEC: 110163064
MALB: 109964080
SASA: 100380426(il6ra) 106595086(IL6RA)
ELS: 105024482
SFM: 108923935(il6r)
LCM: 102359769(IL6R)
CMK: 103172814(il6r)
 » show all
Reference
PMID:1872801
  Authors
Schooltink H, Stoyan T, Lenz D, Schmitz H, Hirano T, Kishimoto T, Heinrich PC, Rose-John S
  Title
Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells.
  Journal
Biochem J 277 ( Pt 3):659-64 (1991)
DOI:10.1042/bj2770659
  Sequence
[hsa:3570]
LinkDB

KEGG   ORTHOLOGY: K05071
Entry
K05071                      KO                                     

Name
IL4R, CD124
Definition
interleukin 4 receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease
Disease
H00079  Asthma
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
   04151 PI3K-Akt signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05071  IL4R, CD124; interleukin 4 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05071  IL4R, CD124; interleukin 4 receptor
   04658 Th1 and Th2 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
   04659 Th17 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05071  IL4R, CD124; interleukin 4 receptor
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05071  IL4R, CD124; interleukin 4 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05071  IL4R, CD124; interleukin 4 receptor
   04090 CD molecules
    K05071  IL4R, CD124; interleukin 4 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05071  IL4R, CD124; interleukin 4 receptor
CD molecules [BR:ko04090]
 Proteins
  K05071  CD124, IL4R; interleukin 4 receptor
Other DBs
GO: 0004913
Genes
HSA: 3566(IL4R)
PTR: 454005(IL4R)
PPS: 100969808(IL4R)
GGO: 101124934(IL4R)
PON: 100449812(IL4R)
NLE: 100606206(IL4R)
MCC: 705404(IL4R)
MCF: 102133649(IL4R)
CSAB: 103230069(IL4R)
RRO: 104665638(IL4R)
RBB: 108538856(IL4R)
CJC: 100412639(IL4R)
SBQ: 101044733(IL4R)
MMU: 16190(Il4ra)
MCAL: 110299093(Il4r)
MPAH: 110322992(Il4r)
RNO: 25084(Il4r)
MUN: 110564641(Il4r)
CGE: 100762840(Il4r)
NGI: 103741011(Il4r)
HGL: 101704138(Il4r)
CCAN: 109698033(Il4r)
OCU: 100337721(IL4R)
TUP: 102469844(IL4R)
CFA: 489957(IL4R)
VVP: 112929179(IL4R)
AML: 100476095(IL4R)
UMR: 103657902(IL4R)
UAH: 113267608(IL4R)
ORO: 101373228(IL4R)
ELK: 111162191
FCA: 101096277(IL4R)
PTG: 102949893(IL4R)
PPAD: 109256524(IL4R)
AJU: 106966182(IL4R)
BTA: 404154(IL4R)
BOM: 102273764(IL4R)
BIU: 109578521(IL4R)
BBUB: 102394204(IL4R)
CHX: 102176382(IL4R)
OAS: 101109063(IL4R)
SSC: 397614(IL4R)
CFR: 102504937(IL4R)
CDK: 105098257(IL4R)
BACU: 103017383(IL4R)
LVE: 103085500(IL4R)
OOR: 101281237(IL4R)
DLE: 111182213(IL4R)
PCAD: 102979109(IL4R)
ECB: 791252(IL4R)
EPZ: 103556347(IL4R)
EAI: 106829083(IL4R)
MYB: 102243995
MYD: 102752440(IL4R)
HAI: 109385965(IL4R)
DRO: 112304724 112304842(IL4R)
PALE: 102882815(IL4R)
RAY: 107506151(IL4R)
MJV: 108405149(IL4R)
LAV: 100654822(IL4R)
TMU: 101351007
MDO: 103092514(IL4R)
SHR: 100922104(IL4R)
PCW: 110221658(IL4R)
OAA: 103164911(IL4R)
GGA: 416585(IL4R)
MGP: 100541265(IL4R)
CJO: 107320714(IL4R)
NMEL: 110405596(IL4R)
APLA: 101796552(IL4R)
ACYG: 106046042(IL4R)
TGU: 100220266(IL4R)
LSR: 110477758(IL4R)
SCAN: 103817792(IL4R)
GFR: 102032458(IL4R)
FAB: 101812385(IL4R)
PHI: 102114232(IL4R)
PMAJ: 107211179(IL4R)
CCAE: 111936216(IL4R)
CCW: 104684903(IL4R)
ETL: 114061435(IL4R)
FPG: 101913747(IL4R)
FCH: 102059925(IL4R)
CLV: 102092650(IL4R)
EGZ: 104131347(IL4R)
NNI: 104015288(IL4R)
ACUN: 113485935(IL4R)
PADL: 103913920(IL4R)
AAM: 106486134(IL4R)
ASN: 102384900
AMJ: 102563749(IL4R)
PSS: 102459395(IL4R)
CMY: 102929479(IL4R)
CPIC: 101942260(IL4R)
ACS: 103281083(il4r)
PVT: 110085007
PBI: 103065038(IL4R)
TSR: 106546610(IL4R)
PMUA: 114584165(IL4R)
XTR: 101732450(il4r) 105948365
DRE: 563674(il4r.2)
SRX: 107745579
IPU: 108257347(il4r) 108280483
PHYP: 113535949(il4r) 113546473
AMEX: 111195543
EEE: 113575903(il4r)
ONL: 100705710
XMA: 111608325
CVG: 107086945
AOCE: 111587969
CSEM: 103398546
POV: 109624836
LCF: 108877014
SDU: 111219228
BPEC: 110175441
SASA: 100195064(il4ra) 106601108
SALP: 111979922
SFM: 108932964
PKI: 111846440(il4r)
LCM: 102349939
CMK: 103186635(il4r)
 » show all
Reference
PMID:2307934
  Authors
Idzerda RL, March CJ, Mosley B, Lyman SD, Vanden Bos T, Gimpel SD, Din WS, Grabstein KH, Widmer MB, Park LS, et al.
  Title
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
  Journal
J Exp Med 171:861-73 (1990)
DOI:10.1084/jem.171.3.861
  Sequence
[hsa:3566]
Reference
PMID:8124718
  Authors
Keegan AD, Nelms K, White M, Wang LM, Pierce JH, Paul WE
  Title
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.
  Journal
Cell 76:811-20 (1994)
DOI:10.1016/0092-8674(94)90356-5
LinkDB

KEGG   ORTHOLOGY: K05072
Entry
K05072                      KO                                     

Name
IL7R, CD127
Definition
interleukin 7 receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04068  FoxO signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
ko05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04068 FoxO signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04151 PI3K-Akt signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05072  IL7R, CD127; interleukin 7 receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05072  IL7R, CD127; interleukin 7 receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05072  IL7R, CD127; interleukin 7 receptor
  09163 Immune disease
   05340 Primary immunodeficiency
    K05072  IL7R, CD127; interleukin 7 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05072  IL7R, CD127; interleukin 7 receptor
   04090 CD molecules
    K05072  IL7R, CD127; interleukin 7 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05072  IL7R, CD127; interleukin 7 receptor
CD molecules [BR:ko04090]
 Proteins
  K05072  CD127, IL7R; interleukin 7 receptor
Other DBs
GO: 0004917
Genes
HSA: 3575(IL7R)
PTR: 461922(IL7R)
PPS: 100981232(IL7R)
GGO: 101140372(IL7R)
PON: 100461835(IL7R)
NLE: 100583768(IL7R)
MCC: 699869(IL7R)
MCF: 102143679(IL7R)
CSAB: 103215123(IL7R)
RRO: 104662030(IL7R)
RBB: 108533533(IL7R)
CJC: 100397720(IL7R)
SBQ: 101044161(IL7R)
MMU: 16197(Il7r)
MCAL: 110310926(Il7r)
MPAH: 110329173(Il7r)
RNO: 294797(Il7r)
MUN: 110542896(Il7r)
CGE: 100757700(Il7r)
NGI: 103741311(Il7r)
HGL: 101710077(Il7r)
CCAN: 109698833(Il7r)
OCU: 100343726(IL7R)
TUP: 102499643(IL7R)
CFA: 612582(IL7R)
VVP: 112933551(IL7R)
AML: 100477617(IL7R)
UMR: 103664716(IL7R)
UAH: 113260884(IL7R)
ORO: 101385299(IL7R)
ELK: 111141253
FCA: 101100697(IL7R)
PTG: 102953956(IL7R)
PPAD: 109267711(IL7R)
AJU: 106979009(IL7R)
BTA: 521554(IL7R)
BOM: 102284629(IL7R)
BIU: 109575020(IL7R)
BBUB: 102400952(IL7R)
CHX: 102175248(IL7R)
OAS: 101111126(IL7R)
SSC: 100271930(IL7R)
CFR: 102515501(IL7R)
CDK: 105087002(IL7R)
BACU: 103010049(IL7R)
LVE: 103089375(IL7R)
OOR: 101275057(IL7R)
DLE: 111187554(IL7R)
PCAD: 102992873(IL7R)
EPZ: 103545416(IL7R)
EAI: 106824753(IL7R)
MYB: 102264253(IL7R)
MYD: 102772772(IL7R)
MNA: 107546370(IL7R)
HAI: 109376825(IL7R)
DRO: 112321141(IL7R)
PALE: 102889092(IL7R)
RAY: 107509706(IL7R)
MJV: 108406858(IL7R)
LAV: 100671266(IL7R)
TMU: 101351100
MDO: 100020565(IL7R)
SHR: 100915478(IL7R)
PCW: 110214720(IL7R)
OAA: 100078445(IL7R)
GGA: 426054(IL7R)
MGP: 100542453(IL7R)
CJO: 107305872(IL7R)
NMEL: 110389974(IL7R)
APLA: 101800042(IL7R)
ACYG: 106036382(IL7R)
TGU: 100226205(IL7R)
LSR: 110482656(IL7R)
SCAN: 103821063(IL7R)
GFR: 102033898(IL7R)
FAB: 101816330(IL7R)
PHI: 102109259(IL7R)
PMAJ: 107216341(IL7R)
CCAE: 111940971(IL7R)
CCW: 104686602(IL7R)
ETL: 114066153(IL7R)
FPG: 101911430(IL7R)
FCH: 102052979(IL7R)
CLV: 102085807(IL7R)
EGZ: 104133924(IL7R)
NNI: 104018643(IL7R)
ACUN: 113489797(IL7R)
PADL: 103921479(IL7R)
AAM: 106499523(IL7R)
ASN: 102368640(IL7R)
AMJ: 102558184(IL7R)
PSS: 102449770(IL7R)
CMY: 102932302(IL7R)
CPIC: 101937386(IL7R)
ACS: 103279695(il7r)
PVT: 110080088(IL7R)
PBI: 103058565(IL7R)
PMUR: 107297967(IL7R)
TSR: 106551942(IL7R)
PMUA: 114606663(IL7R)
GJA: 107108287(IL7R)
XTR: 116408012(il7r)
DRE: 100134973(il7r)
IPU: 108279371(il7r)
PHYP: 113541790(il7r)
AMEX: 103047579(il7r)
EEE: 113573243(il7r)
TRU: 101078727(il7r)
LCO: 104936386(il7r)
MZE: 101477974(il7r)
ONL: 102082329(il7r)
OLA: 110013505(il7r)
XMA: 102218066(il7r)
XCO: 114150235(il7r)
PRET: 103474046
CVG: 107095097(il7r)
NFU: 107374989(il7r)
KMR: 108245570(il7r)
ALIM: 106527579
CSEM: 103390387
SDU: 111238700(il7r)
SLAL: 111652916(il7r)
HCQ: 109523342(il7r)
BPEC: 110161723(il7r)
MALB: 109973109(il7r)
OTW: 112219510 112257526(il7r)
SALP: 111961414 111982155(il7r)
ELS: 105014762(il7r)
SFM: 108932322(il7r)
PKI: 111842105
 » show all
Reference
PMID:2317865
  Authors
Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, et al.
  Title
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
  Journal
Cell 60:941-51 (1990)
DOI:10.1016/0092-8674(90)90342-C
  Sequence
[hsa:3575]
Reference
PMID:8266077
  Authors
Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ
  Title
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.
  Journal
Science 262:1877-80 (1993)
DOI:10.1126/science.8266077
LinkDB

KEGG   ORTHOLOGY: K05130
Entry
K05130                      KO                                     

Name
IFNAR1
Definition
interferon receptor 1
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05130  IFNAR1; interferon receptor 1
   04151 PI3K-Akt signaling pathway
    K05130  IFNAR1; interferon receptor 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05130  IFNAR1; interferon receptor 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05130  IFNAR1; interferon receptor 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05130  IFNAR1; interferon receptor 1
   04621 NOD-like receptor signaling pathway
    K05130  IFNAR1; interferon receptor 1
   04650 Natural killer cell mediated cytotoxicity
    K05130  IFNAR1; interferon receptor 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05130  IFNAR1; interferon receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05130  IFNAR1; interferon receptor 1
  09172 Infectious disease: viral
   05161 Hepatitis B
    K05130  IFNAR1; interferon receptor 1
   05160 Hepatitis C
    K05130  IFNAR1; interferon receptor 1
   05171 Coronavirus disease - COVID-19
    K05130  IFNAR1; interferon receptor 1
   05164 Influenza A
    K05130  IFNAR1; interferon receptor 1
   05162 Measles
    K05130  IFNAR1; interferon receptor 1
   05168 Herpes simplex virus 1 infection
    K05130  IFNAR1; interferon receptor 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05130  IFNAR1; interferon receptor 1
   05169 Epstein-Barr virus infection
    K05130  IFNAR1; interferon receptor 1
   05165 Human papillomavirus infection
    K05130  IFNAR1; interferon receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05130  IFNAR1; interferon receptor 1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05130  IFNAR1; interferon receptor 1
Other DBs
GO: 0004905
Genes
HSA: 3454(IFNAR1)
PTR: 458516(IFNAR1)
PPS: 100995446(IFNAR1)
GGO: 101141158(IFNAR1)
PON: 100443118(IFNAR1)
NLE: 100583382(IFNAR1)
MCC: 699604(IFNAR1)
MCF: 101926190(IFNAR1)
CSAB: 103216875(IFNAR1)
RRO: 104658750(IFNAR1)
RBB: 108536856(IFNAR1)
CJC: 100410306(IFNAR1)
SBQ: 101035044(IFNAR1)
MMU: 15975(Ifnar1)
MCAL: 110311756(Ifnar1)
MPAH: 110329827(Ifnar1)
RNO: 288264(Ifnar1)
MUN: 110541917(Ifnar1)
CGE: 100768581(Ifnar1)
NGI: 103736454
HGL: 101724158(Ifnar1)
CCAN: 109686809
OCU: 100338604(IFNAR1)
TUP: 102480854(IFNAR1)
CFA: 100856529(IFNAR1) 609830
VVP: 112909256(IFNAR1)
AML: 100481921(IFNAR1)
UMR: 103673220(IFNAR1)
UAH: 113264796(IFNAR1)
ORO: 101370046(IFNAR1)
ELK: 111155707
FCA: 101092535(IFNAR1)
PTG: 102955444(IFNAR1)
PPAD: 109249714(IFNAR1)
AJU: 106966457(IFNAR1)
BTA: 282257(IFNAR1)
BOM: 102275793(IFNAR1)
BIU: 109570535(IFNAR1)
BBUB: 102394317(IFNAR1)
CHX: 102191552(IFNAR1)
OAS: 443126(IFNAR1)
SSC: 396658(IFNAR1)
CFR: 102523764(IFNAR1)
CDK: 105089868(IFNAR1)
BACU: 102998082(IFNAR1)
LVE: 103068842(IFNAR1)
OOR: 101284215(IFNAR1)
DLE: 111163780(IFNAR1)
PCAD: 102991034(IFNAR1)
ECB: 100063402(IFNAR1)
EPZ: 103549120(IFNAR1)
EAI: 106832840(IFNAR1)
MYB: 102245971(IFNAR1)
MYD: 102772617(IFNAR1)
MNA: 107537477(IFNAR1)
HAI: 109373231(IFNAR1)
DRO: 112305552(IFNAR1)
PALE: 102892040(IFNAR1)
RAY: 107519592(IFNAR1)
MJV: 108396596(IFNAR1)
LAV: 100667586(IFNAR1)
TMU: 101361715
SHR: 100919064(IFNAR1)
PCW: 110214849
OAA: 100083477(IFNAR1)
GGA: 395665(IFNAR1)
MGP: 100542669(IFNAR1)
CJO: 107322958(IFNAR1)
NMEL: 110402456(IFNAR1)
APLA: 101790975(IFNAR1)
ACYG: 106043409(IFNAR1)
TGU: 115490564(IFNAR1)
LSR: 110474945(IFNAR1)
SCAN: 103824810(IFNAR1)
GFR: 102044653(IFNAR1)
FAB: 101814442(IFNAR1)
PHI: 102110908(IFNAR1)
PMAJ: 107198759(IFNAR1)
CCAE: 111928918
CCW: 104698093(IFNAR1)
ETL: 114071602(IFNAR1)
FPG: 101919760(IFNAR1)
FCH: 102054913(IFNAR1)
CLV: 102088758(IFNAR1)
EGZ: 104128164(IFNAR1)
NNI: 104020173(IFNAR1)
ACUN: 113479018(IFNAR1)
PADL: 103920316(IFNAR1)
AAM: 106494990(IFNAR1)
ASN: 102381089(IFNAR1)
AMJ: 102567201(IFNAR1)
PSS: 102462024(IFNAR1)
CMY: 102945791(IFNAR1)
CPIC: 101942233(IFNAR1)
ACS: 103281135(ifnar1)
PVT: 110080372(IFNAR1)
PBI: 103064969(IFNAR1)
PMUR: 107290638(IFNAR1)
PMUA: 114596050(IFNAR1)
GJA: 107121921
XTR: 100498552(ifnar1)
NPR: 108794147
SANH: 107700959
SGH: 107558503
TRU: 101071242
SFM: 108929004
PKI: 111834154
LCM: 102345381(IFNAR1)
 » show all
Reference
PMID:2153461
  Authors
Uze G, Lutfalla G, Gresser I
  Title
Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA.
  Journal
Cell 60:225-34 (1990)
DOI:10.1016/0092-8674(90)90738-Z
  Sequence
[hsa:3454]
LinkDB

KEGG   ORTHOLOGY: K05131
Entry
K05131                      KO                                     

Name
IFNAR2
Definition
interferon receptor 2
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko05160  Hepatitis C
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05131  IFNAR2; interferon receptor 2
   04151 PI3K-Akt signaling pathway
    K05131  IFNAR2; interferon receptor 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05131  IFNAR2; interferon receptor 2
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05131  IFNAR2; interferon receptor 2
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05131  IFNAR2; interferon receptor 2
   04621 NOD-like receptor signaling pathway
    K05131  IFNAR2; interferon receptor 2
   04650 Natural killer cell mediated cytotoxicity
    K05131  IFNAR2; interferon receptor 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05131  IFNAR2; interferon receptor 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05131  IFNAR2; interferon receptor 2
  09172 Infectious disease: viral
   05160 Hepatitis C
    K05131  IFNAR2; interferon receptor 2
   05171 Coronavirus disease - COVID-19
    K05131  IFNAR2; interferon receptor 2
   05164 Influenza A
    K05131  IFNAR2; interferon receptor 2
   05162 Measles
    K05131  IFNAR2; interferon receptor 2
   05168 Herpes simplex virus 1 infection
    K05131  IFNAR2; interferon receptor 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05131  IFNAR2; interferon receptor 2
   05169 Epstein-Barr virus infection
    K05131  IFNAR2; interferon receptor 2
   05165 Human papillomavirus infection
    K05131  IFNAR2; interferon receptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05131  IFNAR2; interferon receptor 2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05131  IFNAR2; interferon receptor 2
Other DBs
GO: 0004905
Genes
HSA: 3455(IFNAR2)
PTR: 473965(IFNAR2)
PPS: 100995792(IFNAR2)
GGO: 101140784(IFNAR2)
PON: 100441293(IFNAR2)
NLE: 100599809(IFNAR2)
MCC: 699726(IFNAR2)
MCF: 102140083(IFNAR2)
CSAB: 103216889(IFNAR2)
RRO: 104658748(IFNAR2)
RBB: 108536852(IFNAR2)
MMU: 15976(Ifnar2)
MCAL: 110311924(Ifnar2)
MPAH: 110329735(Ifnar2)
RNO: 686326(Ifnar2)
MUN: 110541888(Ifnar2)
CGE: 100768006
NGI: 103736458(Ifnar2)
HGL: 101722391(Ifnar2)
CCAN: 109699947(Ifnar2)
OCU: 100338097(IFNAR2)
TUP: 102477904(IFNAR2)
CFA: 100856468(IFNAR2) 487737
VVP: 112909270(IFNAR2)
AML: 100482679(IFNAR2)
ORO: 101386107(IFNAR2)
ELK: 111155645
FCA: 101090285(IFNAR2)
PTG: 102954859(IFNAR2)
PPAD: 109249711(IFNAR2)
AJU: 106966459(IFNAR2)
BTA: 282258(IFNAR2)
BOM: 102275218(IFNAR2)
BIU: 109572614
BBUB: 102394946(IFNAR2)
CHX: 102175057(IFNAR2)
OAS: 443363(IFNAR2)
SSC: 100533555(IFNAR2)
CFR: 102518206(IFNAR2)
CDK: 105089871(IFNAR2)
BACU: 103020704(IFNAR2)
LVE: 103069127(IFNAR2)
OOR: 101283958(IFNAR2)
DLE: 111163874(IFNAR2)
PCAD: 102989482(IFNAR2)
ECB: 100052489(IFNAR2)
EPZ: 103549136(IFNAR2)
EAI: 106832843(IFNAR2)
MYB: 102259457(IFNAR2)
MYD: 102772901(IFNAR2)
HAI: 109373246(IFNAR2)
DRO: 112305536(IFNAR2)
PALE: 102891485(IFNAR2)
RAY: 107519578(IFNAR2)
MJV: 108409505(IFNAR2)
LAV: 100672898(IFNAR2)
TMU: 101354122
MDO: 103092556(IFNAR2)
SHR: 105750087(IFNAR2)
PCW: 110214853(IFNAR2)
OAA: 103170687(IFNAR2)
GGA: 395664(IFNAR2)
MGP: 100539587(IFNAR2)
CJO: 107322936(IFNAR2)
NMEL: 110402433(IFNAR2)
APLA: 101804315(IFNAR2)
ACYG: 106043436(IFNAR2)
TGU: 115497673(IFNAR2)
LSR: 110474946(IFNAR2)
SCAN: 103824806(IFNAR2)
GFR: 102042202(IFNAR2)
FAB: 101814062(IFNAR2)
PHI: 102101660(IFNAR2)
PMAJ: 107198545
CCAE: 111928947(IFNAR2)
CCW: 104698065
ETL: 114071273(IFNAR2)
FPG: 101919412(IFNAR2)
FCH: 102055258(IFNAR2)
CLV: 102097241(IFNAR2)
EGZ: 104128224(IFNAR2)
NNI: 104020172(IFNAR2)
ACUN: 113477658(IFNAR2)
PADL: 103920254(IFNAR2)
AAM: 106494988(IFNAR2)
ASN: 102381921(IFNAR2)
AMJ: 102566586(IFNAR2)
PSS: 102462520(IFNAR2)
CMY: 102945561(IFNAR2)
CPIC: 101941521(IFNAR2)
ACS: 103281133(ifnar2)
PVT: 110080371(IFNAR2)
PBI: 103063466(IFNAR2)
PMUR: 107290611(IFNAR2)
TSR: 106550452
GJA: 107110548(IFNAR2)
XTR: 100496877(ifnar2.2) 779845(ifnar2.1)
DRE: 777653(crfb2)
SRX: 107746586
SANH: 107653241
SGH: 107569726
CCAR: 109105674
IPU: 108266953
AMEX: 103046016
LCO: 104932498
XMA: 102219036
XCO: 114147537
PRET: 103461789
NFU: 107374287
KMR: 108251686
ALIM: 106530220
CSEM: 103392359
SDU: 111228083
SLAL: 111663409
HCQ: 109519251
BPEC: 110162048
MALB: 109951988
SALP: 111959819
ELS: 105031504
SFM: 108922254
PKI: 111860691
CMK: 103186765
RTP: 109928467
 » show all
Reference
PMID:8181059
  Authors
Novick D, Cohen B, Rubinstein M
  Title
The human interferon alpha/beta receptor: characterization and molecular cloning.
  Journal
Cell 77:391-400 (1994)
DOI:10.1016/0092-8674(94)90154-6
  Sequence
[hsa:3455]
LinkDB

KEGG   ORTHOLOGY: K05079
Entry
K05079                      KO                                     

Name
EPOR
Definition
erythropoietin receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
Disease
H00236  Congenital polycythemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05079  EPOR; erythropoietin receptor
   04151 PI3K-Akt signaling pathway
    K05079  EPOR; erythropoietin receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05079  EPOR; erythropoietin receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05079  EPOR; erythropoietin receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05079  EPOR; erythropoietin receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05079  EPOR; erythropoietin receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  Prolactin receptor family
   K05079  EPOR; erythropoietin receptor
Other DBs
GO: 0004900
Genes
HSA: 2057(EPOR)
PTR: 455728(EPOR)
PPS: 100980274(EPOR)
GGO: 101147948(EPOR)
PON: 100452294(EPOR)
NLE: 100593505(EPOR)
MCC: 714546(EPOR)
MCF: 102138718(EPOR)
CSAB: 103233928(EPOR)
RRO: 104670444(EPOR)
RBB: 108527906(EPOR)
CJC: 100389634(EPOR)
SBQ: 101035236(EPOR)
MMU: 13857(Epor)
MCAL: 110301928(Epor)
MPAH: 110328285(Epor)
RNO: 24336(Epor)
MUN: 110552478(Epor)
CGE: 100769376(Epor)
NGI: 103734578(Epor)
HGL: 101710668(Epor)
CCAN: 109692570(Epor)
OCU: 100355350(EPOR)
TUP: 102479112(EPOR)
CFA: 484943(EPOR)
VVP: 112908152(EPOR)
AML: 100484014(EPOR)
UMR: 103678709(EPOR)
UAH: 113243022(EPOR)
ORO: 101385485(EPOR)
ELK: 111162487
FCA: 101081364(EPOR)
PTG: 102948529(EPOR)
PPAD: 109254070(EPOR)
AJU: 106983947(EPOR)
BTA: 281144(EPOR)
BOM: 102265298(EPOR)
BIU: 109561621(EPOR)
BBUB: 102412286(EPOR)
CHX: 102191790(EPOR)
OAS: 443227(EPOR)
SSC: 397554(EPOR)
CFR: 102509678(EPOR)
CDK: 105087606(EPOR)
BACU: 103003915(EPOR)
LVE: 103090844(EPOR)
OOR: 101286556(EPOR)
PCAD: 102980451(EPOR)
ECB: 100057022(EPOR)
EPZ: 103542573(EPOR)
EAI: 106846605(EPOR)
MYB: 102240499(EPOR)
MYD: 102772788(EPOR)
MNA: 107533235(EPOR)
HAI: 109391584(EPOR)
DRO: 112301517(EPOR)
PALE: 102886625(EPOR)
RAY: 107515102(EPOR)
MJV: 108398989(EPOR)
LAV: 100666267(EPOR)
TMU: 101349119
MDO: 100010880(EPOR)
SHR: 100922441(EPOR)
PCW: 110214315(EPOR)
OAA: 100088007(EPOR)
ASN: 102383787(EPOR)
AMJ: 102559844(EPOR)
PSS: 102454146(EPOR)
CMY: 102940437(EPOR)
CPIC: 101950739(EPOR)
ACS: 103277735(epor)
PVT: 110078014(EPOR)
PBI: 103059889(EPOR)
PMUR: 107283453(MPL) 107285119(EPOR)
TSR: 106537750(EPOR)
PMUA: 114587841(EPOR)
GJA: 107115309(EPOR)
XLA: 734211(epor.L)
XTR: 100498534(epor)
NPR: 108799818(EPOR)
DRE: 751109(epor)
IPU: 108259690(epor)
PHYP: 113527855(epor)
AMEX: 103040492(epor)
EEE: 113575240(epor)
TRU: 101071352
LCO: 104934504(epor)
NCC: 104963530
MZE: 101464440
ONL: 100706201
OLA: 101163579
XMA: 102228367
XCO: 114147823(epor)
PRET: 103468330(epor)
CVG: 107096550
NFU: 107376180(epor)
KMR: 108247493
ALIM: 106517823(epor)
AOCE: 111586038
CSEM: 103393663
POV: 109644517
LCF: 108898639
SDU: 111223701
SLAL: 111662520
HCQ: 109530021
BPEC: 110172149
MALB: 109973511(epor)
SASA: 100195206(epor) 106601362(EPOR)
SALP: 111981260(epor)
ELS: 105013431
SFM: 108925969(epor) 108939965
LCM: 102346018(EPOR)
RTP: 109920561(epor)
 » show all
Reference
  Authors
Aizawa Y, Nogawa N, Kosaka N, Maeda Y, Watanabe T, Miyazaki H, Kato T
  Title
Expression of erythropoietin receptor-like molecule in Xenopus laevis and erythrocytopenia upon administration of its recombinant soluble form.
  Journal
J Biochem 138:167-75 (2005)
DOI:10.1093/jb/mvi113
  Sequence
[xla:734211]
Reference
  Authors
Grotzinger J
  Title
Molecular mechanisms of cytokine receptor activation.
  Journal
Biochim Biophys Acta 1592:215-23 (2002)
DOI:10.1016/S0167-4889(02)00316-6
LinkDB

KEGG   ORTHOLOGY: K05061
Entry
K05061                      KO                                     

Name
CSF3R, CD114
Definition
granulocyte colony-stimulating factor receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
Disease
H02410  Myelodysplastic/myeloproliferative neoplasms
H02412  Atypical chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
   04151 PI3K-Akt signaling pathway
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
   04090 CD molecules
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  Prolactin receptor family
   K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
CD molecules [BR:ko04090]
 Proteins
  K05061  CD114, CSF3R; colony stimulating factor 3 receptor (granulocyte)
Genes
HSA: 1441(CSF3R)
PTR: 456756(CSF3R)
PPS: 100974292(CSF3R)
GGO: 101128750(CSF3R)
PON: 100433338(CSF3R)
NLE: 100594510(CSF3R)
MCC: 713485(CSF3R)
MCF: 102132219(CSF3R)
CSAB: 103225104(CSF3R)
RRO: 104660161(CSF3R)
RBB: 108537272(CSF3R)
CJC: 100393434(CSF3R)
SBQ: 101042318(CSF3R)
MMU: 12986(Csf3r)
MCAL: 110293219(Csf3r)
MPAH: 110323626(Csf3r)
RNO: 298518(Csf3r)
MUN: 110540287(Csf3r)
CGE: 100760185(Csf3r)
NGI: 103733325(Csf3r)
HGL: 101723599(Csf3r)
CCAN: 109690426(Csf3r)
OCU: 100342746(CSF3R)
TUP: 102471059(CSF3R)
CFA: 607605(CSF3R)
VVP: 112914671(CSF3R)
AML: 100464681(CSF3R)
UMR: 103666378(CSF3R)
UAH: 113268281(CSF3R)
ORO: 101377969(CSF3R)
ELK: 111143352
FCA: 101089787(CSF3R)
PTG: 102961715(CSF3R)
PPAD: 109255488(CSF3R)
AJU: 106973256(CSF3R)
BOM: 102274942(CSF3R)
BIU: 109556495(CSF3R)
BBUB: 102410273(CSF3R)
CHX: 102175546(CSF3R)
OAS: 101118070(CSF3R)
SSC: 100622336(CSF3R)
CFR: 102505807(CSF3R)
CDK: 105086937(CSF3R)
BACU: 103000462(CSF3R)
LVE: 103075275(CSF3R)
OOR: 101275322(CSF3R)
DLE: 111175589(CSF3R)
PCAD: 102980945(CSF3R)
ECB: 100069253(CSF3R)
EPZ: 103549278(CSF3R)
EAI: 106830549(CSF3R)
MYB: 102241961(CSF3R)
MYD: 102764425(CSF3R)
MNA: 107542574(CSF3R)
HAI: 109390482(CSF3R)
DRO: 112299557(CSF3R)
PALE: 102897878(CSF3R)
RAY: 107512067(CSF3R)
MJV: 108400801(CSF3R)
LAV: 100665706(CSF3R)
TMU: 101343066
MDO: 100031592(CSF3R)
SHR: 100928707(CSF3R)
PCW: 110206350(CSF3R)
OAA: 100080173(CSF3R)
GGA: 419620(CSF3R)
MGP: 100542145(CSF3R)
CJO: 107324075(CSF3R)
NMEL: 110387487(CSF3R)
APLA: 101791747(CSF3R)
ACYG: 106038086(CSF3R)
TGU: 100229496(CSF3R)
LSR: 110484278(CSF3R)
SCAN: 103822640(CSF3R)
GFR: 102033859(CSF3R)
FAB: 101807604(CSF3R)
PHI: 102101360(CSF3R)
PMAJ: 107214013(CSF3R)
CCAE: 111938933(CSF3R)
CCW: 104694794(CSF3R)
ETL: 114058886(CSF3R)
FPG: 106112048(CSF3R)
FCH: 106630793(CSF3R)
CLV: 106145641(CSF3R)
NNI: 104017904
AAM: 106490870(CSF3R)
AMJ: 102560832(CSF3R)
PSS: 102460143(CSF3R)
CMY: 102931914(CSF3R)
CPIC: 101942477(CSF3R)
PVT: 110082761(CSF3R)
PBI: 112542138(CSF3R)
PMUR: 114922295(CSF3R)
TSR: 106543650(CSF3R)
PMUA: 114601738(CSF3R)
GJA: 107110150(CSF3R)
XLA: 108704665 446770(csf3r.L)
XTR: 100498116(csf3r)
NPR: 108804707(CSF3R)
DRE: 100134935(csf3r)
CCAR: 109104913
IPU: 108269562(csf3r)
PHYP: 113533987(csf3r)
AMEX: 103033065(csf3r)
EEE: 113578072(csf3r)
TRU: 101072170(csf3r)
LCO: 104919598(csf3r)
NCC: 104941919
MZE: 101478204(csf3r)
ONL: 100703184(csf3r)
OLA: 101166496(csf3r)
XMA: 102231746(csf3r)
XCO: 114142021(csf3r)
PRET: 103477807(csf3r)
CVG: 107084721
NFU: 107396619
KMR: 108235335(csf3r)
ALIM: 106524680(csf3r)
AOCE: 111572351(csf3r)
CSEM: 103387876(csf3r)
POV: 109633009(csf3r)
LCF: 108899580(csf3r)
SDU: 111235806(csf3r)
SLAL: 111661606(csf3r)
HCQ: 109513114(csf3r)
BPEC: 110174290(csf3r)
MALB: 109954603(csf3r)
SASA: 100137055(csf3r)
ELS: 105028375
SFM: 108927808(csf3r)
PKI: 111848842(csf3r)
LCM: 102353589(CSF3R)
 » show all
Reference
PMID:2147944
  Authors
Larsen A, Davis T, Curtis BM, Gimpel S, Sims JE, Cosman D, Park L, Sorensen E, March CJ, Smith CA
  Title
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
  Journal
J Exp Med 172:1559-70 (1990)
DOI:10.1084/jem.172.6.1559
  Sequence
[hsa:1441]
Reference
PMID:1717255
  Authors
Fukunaga R, Ishizaka-Ikeda E, Pan CX, Seto Y, Nagata S
  Title
Functional domains of the granulocyte colony-stimulating factor receptor.
  Journal
EMBO J 10:2855-65 (1991)
DOI:10.1002/j.1460-2075.1991.tb07835.x
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