KEGG   ORTHOLOGY: K05147
Entry
K05147                      KO                                     

Name
TNFRSF11A, RANK, CD265
Definition
tumor necrosis factor receptor superfamily member 11A
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04064  NF-kappa B signaling pathway
ko04380  Osteoclast differentiation
ko04917  Prolactin signaling pathway
ko05323  Rheumatoid arthritis
Disease
H00436  Osteopetrosis
H00437  Paget disease of bone
H02042  Familial expansile osteolysis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
 09160 Human Diseases
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
   04090 CD molecules
    K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
Cytokine receptors [BR:ko04050]
 Tumor necrosis factor receptors
  TNF receptor superfamily
   K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
CD molecules [BR:ko04090]
 Proteins
  K05147  CD265, TNFRSF11A; tumor necrosis factor receptor superfamily, member 11a, activator of NFKB
Other DBs
GO: 0005031
Genes
HSA: 8792(TNFRSF11A)
PTR: 468560(TNFRSF11A)
PPS: 100991913(TNFRSF11A)
GGO: 101133276(TNFRSF11A)
PON: 100433235(TNFRSF11A)
NLE: 100600585(TNFRSF11A)
MCC: 100424175(TNFRSF11A)
MCF: 102128119(TNFRSF11A)
CSAB: 103244174(TNFRSF11A)
RRO: 104682263(TNFRSF11A)
RBB: 108526386(TNFRSF11A)
CJC: 100393710(TNFRSF11A)
SBQ: 101052330(TNFRSF11A)
MMU: 21934(Tnfrsf11a)
MCAL: 110303160(Tnfrsf11a)
MPAH: 110322494(Tnfrsf11a)
RNO: 498206(Tnfrsf11a)
MUN: 110539357(Tnfrsf11a)
CGE: 100753416(Tnfrsf11a)
NGI: 103740116(Tnfrsf11a)
HGL: 101718050(Tnfrsf11a)
CCAN: 109685497(Tnfrsf11a)
OCU: 100358260(TNFRSF11A)
TUP: 102482158(TNFRSF11A)
CFA: 483957(TNFRSF11A)
VVP: 112919200(TNFRSF11A)
AML: 100483336(TNFRSF11A)
UMR: 103676207(TNFRSF11A)
UAH: 113253483(TNFRSF11A)
ORO: 101379212(TNFRSF11A)
ELK: 111154251
FCA: 101090651(TNFRSF11A)
PTG: 102957203(TNFRSF11A)
PPAD: 109275640
AJU: 113602289(TNFRSF11A)
BTA: 530884(TNFRSF11A)
BOM: 102286841(TNFRSF11A)
BIU: 109577693(TNFRSF11A)
BBUB: 102395034(TNFRSF11A)
CHX: 102182930(TNFRSF11A)
OAS: 101118842(TNFRSF11A)
SSC: 100521706(TNFRSF11A)
CFR: 102523321(TNFRSF11A)
CDK: 105088996(TNFRSF11A)
BACU: 103010843(TNFRSF11A)
LVE: 103084330(TNFRSF11A)
OOR: 101270027(TNFRSF11A)
DLE: 111180204(TNFRSF11A)
PCAD: 102988430(TNFRSF11A)
ECB: 100056617(TNFRSF11A)
EPZ: 103562575(TNFRSF11A)
EAI: 106832859(TNFRSF11A)
MYB: 102249492(TNFRSF11A)
MYD: 102768589(TNFRSF11A)
MNA: 107545409(TNFRSF11A)
HAI: 109390774(TNFRSF11A)
DRO: 112322858(TNFRSF11A)
PALE: 102886170(TNFRSF11A)
RAY: 107501393(TNFRSF11A)
MJV: 108391455(TNFRSF11A)
LAV: 100661891(TNFRSF11A)
TMU: 101355445
MDO: 100024621(TNFRSF11A)
SHR: 100914694(TNFRSF11A)
PCW: 110214743(TNFRSF11A)
OAA: 100084001(TNFRSF11A)
GGA: 769909(TNFRSF11A)
MGP: 100545473(TNFRSF11A)
CJO: 107309599(TNFRSF11A)
NMEL: 110393862(TNFRSF11A)
APLA: 101797241(TNFRSF11A)
TGU: 100232567(TNFRSF11A)
LSR: 110470694(TNFRSF11A)
SCAN: 103815299(TNFRSF11A)
GFR: 102032337(TNFRSF11A)
FAB: 101817392(TNFRSF11A)
PHI: 102100864(TNFRSF11A)
PMAJ: 107200749(TNFRSF11A)
CCAE: 111923866(TNFRSF11A)
CCW: 104698173(TNFRSF11A)
ETL: 114070086(TNFRSF11A)
FPG: 101915765(TNFRSF11A)
FCH: 102053918(TNFRSF11A)
CLV: 102095161(TNFRSF11A)
EGZ: 104123471(TNFRSF11A)
NNI: 104021923(TNFRSF11A)
ACUN: 113477373(TNFRSF11A)
PADL: 103919228(TNFRSF11A)
AAM: 106500204(TNFRSF11A)
ASN: 102381076(TNFRSF11A)
AMJ: 102575500(TNFRSF11A)
PSS: 102446357(TNFRSF11A)
CMY: 102947144(TNFRSF11A)
CPIC: 101939664(TNFRSF11A)
ACS: 100559342(tnfrsf11a)
PVT: 110075410(TNFRSF11A)
PBI: 103067162(TNFRSF11A)
PMUR: 107283579(TNFRSF11A)
TSR: 106551816(TNFRSF11A)
PMUA: 114600983(TNFRSF11A)
GJA: 107124868
XLA: 108719099 108720089
XTR: 100101765(tnfrsf11a)
NPR: 108798474
DRE: 100333821(tnfrsf11a)
SRX: 107727236 107758279
SANH: 107686692 107695382
SGH: 107584986 107595139
CCAR: 109049938
IPU: 108256716(tnfrsf11a)
PHYP: 113541325(tnfrsf11a)
AMEX: 103038583
EEE: 113591902
TRU: 101073524
TNG: GSTEN00015465G001
LCO: 104922590
NCC: 104957084
MZE: 101466954(tnfrsf11a)
ONL: 100690186
OLA: 101164015(tnfrsf11a)
XMA: 102229493
XCO: 114136920
PRET: 103456530(tnfrsf11a)
CVG: 107094196(tnfrsf11a)
NFU: 107382986(tnfrsf11a)
KMR: 108243135(tnfrsf11a)
ALIM: 106517555(tnfrsf11a)
AOCE: 111565920
CSEM: 103376899(tnfrsf11a)
POV: 109629514(tnfrsf11a)
LCF: 108900798
SDU: 111237298
SLAL: 111662986
HCQ: 109515585(tnfrsf11a)
BPEC: 110160990(tnfrsf11a)
MALB: 109963718(tnfrsf11a)
SASA: 106578407(tnfrsf11a) 106590556
OTW: 112215490 112227660
SALP: 111973456 112080814
ELS: 105022048(tnfrsf11a)
SFM: 108919669 108935562
PKI: 111837168
LCM: 102354842
CMK: 103179959(tnfrsf11a)
 » show all
Reference
PMID:9367155
  Authors
Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L
  Title
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
  Journal
Nature 390:175-9 (1997)
DOI:10.1038/36593
  Sequence
[hsa:8792]
Reference
  Authors
Hanada R, Hanada T, Sigl V, Schramek D, Penninger JM
  Title
RANKL/RANK-beyond bones.
  Journal
J Mol Med (Berl) 89:647-56 (2011)
DOI:10.1007/s00109-011-0749-z
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