KEGG   ORTHOLOGY: K05403
Entry
K05403                      KO                                     

Name
TIRAP
Definition
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Pathway
ko04064  NF-kappa B signaling pathway
ko04620  Toll-like receptor signaling pathway
ko05130  Pathogenic Escherichia coli infection
ko05132  Salmonella infection
ko05133  Pertussis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
   05132 Salmonella infection
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
   05133 Pertussis
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
   05152 Tuberculosis
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  09172 Infectious disease: viral
   05161 Hepatitis B
    K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Genes
HSA: 114609(TIRAP)
PTR: 451654(TIRAP)
PPS: 100975220(TIRAP)
GGO: 101139748(TIRAP)
PON: 100440980(TIRAP)
NLE: 100601986(TIRAP)
MCC: 714377(TIRAP)
MCF: 102121169(TIRAP)
CSAB: 103248791(TIRAP)
RRO: 104653954(TIRAP)
RBB: 108542317(TIRAP)
CJC: 100409771(TIRAP)
SBQ: 101038715(TIRAP)
MMU: 117149(Tirap)
MCAL: 110301823(Tirap)
MPAH: 110328152(Tirap)
RNO: 680127(Tirap)
MUN: 110555283(Tirap)
CGE: 100757985(Tirap)
NGI: 103735409(Tirap)
HGL: 101715320(Tirap)
CCAN: 109698469(Tirap)
OCU: 100338708(TIRAP)
TUP: 102471752(TIRAP)
CFA: 609544(TIRAP)
VVP: 112920266(TIRAP)
AML: 100470794(TIRAP)
UMR: 103660655(TIRAP)
UAH: 113259882(TIRAP)
ORO: 101375779(TIRAP)
ELK: 111153868
FCA: 101088688(TIRAP)
PTG: 102970131(TIRAP)
PPAD: 109250350(TIRAP)
AJU: 106974926(TIRAP)
BTA: 531079(TIRAP)
BOM: 102278504(TIRAP)
BIU: 109554591(TIRAP)
BBUB: 102404626(TIRAP)
CHX: 102184789(TIRAP)
OAS: 101118490(TIRAP)
SSC: 100514174(TIRAP)
CFR: 102524429(TIRAP)
CDK: 105094263(TIRAP)
BACU: 103009631(TIRAP)
LVE: 103078296(TIRAP)
OOR: 101284698(TIRAP)
DLE: 111165480(TIRAP)
PCAD: 102979480(TIRAP)
ECB: 100064503(TIRAP)
EPZ: 103549023(TIRAP)
EAI: 106825588 106834020(TIRAP)
MYB: 102260812(TIRAP)
MYD: 102767941 102774520(TIRAP)
MNA: 107530599(TIRAP)
HAI: 109391405(TIRAP)
DRO: 112301793(TIRAP)
PALE: 102879591(TIRAP)
RAY: 107507804(TIRAP)
MJV: 108399058(TIRAP)
LAV: 100660317(TIRAP)
TMU: 101355274
MDO: 100019477(TIRAP)
SHR: 100913329(TIRAP)
PCW: 110218147(TIRAP)
OAA: 100084424(TIRAP)
GGA: 419715(TIRAP)
MGP: 100544782(TIRAP)
CJO: 107324201(TIRAP)
NMEL: 110387703(TIRAP)
APLA: 106017129(TIRAP)
ACYG: 106040636(TIRAP)
TGU: 100220474(C28H19orf25) 105758827(TIRAP)
LSR: 110468189(TIRAP)
SCAN: 103822803(TIRAP)
GFR: 102039379(TIRAP)
FAB: 101813451(TIRAP)
PHI: 102111777(TIRAP)
PMAJ: 107214435(TIRAP)
CCAE: 111939372(TIRAP)
CCW: 104692146(TIRAP)
ETL: 114064610(TIRAP)
FPG: 101910723(TIRAP)
FCH: 102047793(TIRAP)
CLV: 102099033(TIRAP)
EGZ: 104129233(TIRAP)
NNI: 104016675(TIRAP)
ACUN: 113488468(TIRAP)
PADL: 103916420(TIRAP)
ASN: 106722059(TIRAP)
AMJ: 102563698(TIRAP) 102572807(CUNH19orf25)
PSS: 102447956(TIRAP)
CMY: 102947697(TIRAP)
CPIC: 101942636(TIRAP)
ACS: 100567157(tirap)
PVT: 110088814(TIRAP)
PBI: 103065850(TIRAP)
PMUR: 107298040(TIRAP)
TSR: 106548710(TIRAP)
PMUA: 114585471(TIRAP)
GJA: 107119895(TIRAP)
XLA: 108695816 108696876 446390(tirap.L)
XTR: 100491693 733541(tirap)
DRE: 403148(tirap)
SANH: 107692532
AMEX: 111190370(tirap)
TRU: 100134854(tirap)
LCO: 104940498(tirap)
NCC: 104942069(tirap)
MZE: 101483841(tirap)
ONL: 100710220(tirap)
OLA: 101157635(tirap)
XMA: 102237713(tirap)
XCO: 114161422(tirap)
PRET: 103474766(tirap)
CVG: 107083458(tirap)
NFU: 107380709(tirap)
KMR: 108238172(tirap)
ALIM: 106531962(tirap)
AOCE: 111569196(tirap)
POV: 109634523(tirap)
LCF: 108898789(tirap)
SDU: 111233420(tirap)
SLAL: 111665453(tirap)
BPEC: 110162041(tirap)
SASA: 106581078
OTW: 112265616(tirap)
ELS: 105023818(tirap)
LCM: 102359565(TIRAP)
CMK: 103180241(tirap)
RTP: 109924105(tirap)
 » show all
Reference
  Authors
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA
  Title
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.
  Journal
Nature 413:78-83 (2001)
DOI:10.1038/35092578
  Sequence
[hsa:114609]
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