KEGG   ORTHOLOGY: K05411
Entry
K05411                      KO                                     

Name
IRF3
Definition
interferon regulatory factor 3
Pathway
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko05131  Shigellosis
ko05133  Pertussis
ko05135  Yersinia infection
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05411  IRF3; interferon regulatory factor 3
   04621 NOD-like receptor signaling pathway
    K05411  IRF3; interferon regulatory factor 3
   04622 RIG-I-like receptor signaling pathway
    K05411  IRF3; interferon regulatory factor 3
   04623 Cytosolic DNA-sensing pathway
    K05411  IRF3; interferon regulatory factor 3
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K05411  IRF3; interferon regulatory factor 3
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05411  IRF3; interferon regulatory factor 3
   05135 Yersinia infection
    K05411  IRF3; interferon regulatory factor 3
   05133 Pertussis
    K05411  IRF3; interferon regulatory factor 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05411  IRF3; interferon regulatory factor 3
   05161 Hepatitis B
    K05411  IRF3; interferon regulatory factor 3
   05160 Hepatitis C
    K05411  IRF3; interferon regulatory factor 3
   05171 Coronavirus disease - COVID-19
    K05411  IRF3; interferon regulatory factor 3
   05164 Influenza A
    K05411  IRF3; interferon regulatory factor 3
   05162 Measles
    K05411  IRF3; interferon regulatory factor 3
   05168 Herpes simplex virus 1 infection
    K05411  IRF3; interferon regulatory factor 3
   05163 Human cytomegalovirus infection
    K05411  IRF3; interferon regulatory factor 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05411  IRF3; interferon regulatory factor 3
   05169 Epstein-Barr virus infection
    K05411  IRF3; interferon regulatory factor 3
   05165 Human papillomavirus infection
    K05411  IRF3; interferon regulatory factor 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K05411  IRF3; interferon regulatory factor 3
   04131 Membrane trafficking
    K05411  IRF3; interferon regulatory factor 3
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    K05411  IRF3; interferon regulatory factor 3
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    K05411  IRF3; interferon regulatory factor 3
Genes
HSA: 3661(IRF3)
PTR: 747565(IRF3)
PPS: 100977114(IRF3)
GGO: 101144709(IRF3)
PON: 100441280(IRF3)
NLE: 100603099(IRF3)
MCC: 718970(IRF3)
MCF: 102132745(IRF3)
CSAB: 103235050(IRF3)
RRO: 104667206(IRF3)
RBB: 108535826(IRF3)
CJC: 100414132(IRF3)
SBQ: 101033122(IRF3)
MMU: 54131(Irf3)
MCAL: 110298322(Irf3)
MPAH: 110332836(Irf3)
RNO: 292892(Irf3)
CGE: 100765676(Irf3)
NGI: 103743674(Irf3)
HGL: 101722762(Irf3)
CCAN: 109683903(Irf3)
OCU: 103346571(IRF3)
TUP: 102489835(IRF3)
CFA: 476412(IRF3)
VVP: 112931284(IRF3)
AML: 100471184(IRF3)
UMR: 103657131(IRF3)
UAH: 113243290(IRF3)
ORO: 101386524(IRF3)
ELK: 111160645
FCA: 101095934(IRF3)
PTG: 102956602(IRF3)
PPAD: 109253050(IRF3)
AJU: 106983140(IRF3)
BTA: 516979(IRF3)
BOM: 102279593(IRF3)
BIU: 109572224(IRF3)
BBUB: 102396674(IRF3)
CHX: 102171811(IRF3)
OAS: 780485(IRF3)
SSC: 396656(IRF3)
CFR: 102506077(IRF3)
CDK: 105100198(IRF3)
BACU: 103004904(IRF3)
LVE: 103070943(IRF3)
OOR: 101272168(IRF3)
DLE: 111180609(IRF3)
PCAD: 102986279(IRF3)
ECB: 100055868(IRF3)
EPZ: 103541756(IRF3)
EAI: 106824161(IRF3)
MYB: 102241188(IRF3)
MYD: 102760165(IRF3)
MNA: 107531880(IRF3)
HAI: 109391076(IRF3)
DRO: 112310089(IRF3)
PALE: 102878862(IRF3)
RAY: 107498821(IRF3)
MJV: 108400317(IRF3)
LAV: 100667571(IRF3)
TMU: 101348880
MDO: 100030239(IRF3)
SHR: 100933650
PCW: 110219913(IRF3)
OAA: 114814621(IRF3)
ASN: 102368478(IRF3)
AMJ: 102560503(IRF3)
CPIC: 101938664(IRF3)
ACS: 100561376(irf3)
PVT: 110079174(IRF3)
PBI: 103059405(IRF3)
PMUR: 107282419(IRF3)
TSR: 106553402(IRF3)
PMUA: 114582063(IRF3)
GJA: 107108113(IRF3)
XLA: 108695903 108697781 379275(irf3.L)
XTR: 101734275(irf3)
DRE: 564854(irf3)
IPU: 108273898(IRF3)
PHYP: 113527080
AMEX: 103032028
EEE: 113590849
TRU: 101071639
LCO: 104935901(irf3)
NCC: 104948891
MZE: 101466323
ONL: 100702954
OLA: 101158892
XMA: 102228854
XCO: 114156047
PRET: 103481249
CVG: 107097205
NFU: 107387991
KMR: 108237204
ALIM: 106517444
AOCE: 111584600
CSEM: 103382011
POV: 109642328
LCF: 108884442
SDU: 111219805
SLAL: 111658714
HCQ: 109523980
BPEC: 110159564
MALB: 109963625
SASA: 100337625(irf-3)
OTW: 112235560
SALP: 111978255
ELS: 105026239
SFM: 108925144(irf3)
PKI: 111851276(irf3)
LCM: 102348631(IRF3)
 » show all
Reference
PMID:8524823
  Authors
Au WC, Moore PA, Lowther W, Juang YT, Pitha PM
  Title
Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes.
  Journal
Proc Natl Acad Sci U S A 92:11657-61 (1995)
DOI:10.1073/pnas.92.25.11657
  Sequence
[hsa:3661]
LinkDB

KEGG   ORTHOLOGY: K09447
Entry
K09447                      KO                                     

Name
IRF7
Definition
interferon regulatory factor 7
Pathway
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K09447  IRF7; interferon regulatory factor 7
   04621 NOD-like receptor signaling pathway
    K09447  IRF7; interferon regulatory factor 7
   04622 RIG-I-like receptor signaling pathway
    K09447  IRF7; interferon regulatory factor 7
   04623 Cytosolic DNA-sensing pathway
    K09447  IRF7; interferon regulatory factor 7
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K09447  IRF7; interferon regulatory factor 7
  09172 Infectious disease: viral
   05161 Hepatitis B
    K09447  IRF7; interferon regulatory factor 7
   05160 Hepatitis C
    K09447  IRF7; interferon regulatory factor 7
   05164 Influenza A
    K09447  IRF7; interferon regulatory factor 7
   05162 Measles
    K09447  IRF7; interferon regulatory factor 7
   05168 Herpes simplex virus 1 infection
    K09447  IRF7; interferon regulatory factor 7
   05167 Kaposi sarcoma-associated herpesvirus infection
    K09447  IRF7; interferon regulatory factor 7
   05169 Epstein-Barr virus infection
    K09447  IRF7; interferon regulatory factor 7
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09447  IRF7; interferon regulatory factor 7
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    K09447  IRF7; interferon regulatory factor 7
Genes
HSA: 3665(IRF7)
PTR: 450927(IRF7)
PPS: 100991659(IRF7)
GGO: 101138881(IRF7)
PON: 100460542(IRF7)
NLE: 100605304(IRF7)
MCC: 699578(IRF7)
MCF: 102130894(IRF7)
CSAB: 103226003(IRF7)
RRO: 104682894(IRF7)
RBB: 108543524(IRF7)
CJC: 100405036(IRF7)
SBQ: 101034616(IRF7)
MMU: 54123(Irf7)
MCAL: 110297922(Irf7)
MPAH: 110333471(Irf7)
RNO: 293624(Irf7)
MUN: 110553918(Irf7)
CGE: 100755889(Irf7)
NGI: 103751080(Irf7)
HGL: 101710824(Irf7)
CCAN: 109698071(Irf7)
OCU: 100358763(IRF7)
TUP: 102487659(IRF7)
VVP: 112914606(IRF7)
AML: 100474086(IRF7)
UMR: 103671092(IRF7)
UAH: 113248784(IRF7)
ORO: 101374020(IRF7)
ELK: 111150049
FCA: 101084060(IRF7)
PPAD: 109259807(IRF7)
AJU: 106988905(IRF7)
BTA: 100125591(IRF7)
BOM: 102275978(IRF7)
BBUB: 102399283(IRF7)
CHX: 106503773(IRF7)
OAS: 101103683(IRF7)
SSC: 100037289(IRF7)
CFR: 116666573(IRF7)
CDK: 105105431(IRF7)
BACU: 102999216(IRF7)
LVE: 103077222(IRF7)
OOR: 101277458(IRF7)
DLE: 111170280(IRF7)
PCAD: 102996452(IRF7)
ECB: 100055087(IRF7)
EPZ: 103567336(IRF7)
EAI: 106824966(IRF7)
MNA: 107542325(IRF7)
HAI: 109375630(IRF7)
DRO: 112317444(IRF7)
PALE: 102897349(IRF7)
RAY: 107507145(IRF7)
MJV: 108408637(IRF7)
LAV: 100655418(IRF7)
TMU: 101352078
PCW: 110202995(IRF7)
OAA: 103167211(IRF7)
GGA: 396330(IRF7)
MGP: 100545324(IRF7)
CJO: 107314507(IRF7)
NMEL: 110402123(IRF7)
APLA: 101795904
ACYG: 106031780(IRF7)
TGU: 100222919(IRF7)
LSR: 110484492(IRF7)
SCAN: 103824089(IRF7)
GFR: 102042226(IRF7)
FAB: 101807197(IRF7)
PHI: 102105004(IRF7)
PMAJ: 107205854(IRF7)
CCAE: 111930730(IRF7)
CCW: 104690931(IRF7)
ETL: 114068489(IRF7)
FPG: 101922355(IRF7)
FCH: 102060208(IRF7)
CLV: 102095157(IRF7)
EGZ: 104127102(IRF7)
NNI: 104017322(IRF7)
ACUN: 113480983(IRF7)
PADL: 103916457(IRF7)
AAM: 106494854(IRF7)
ASN: 102387082(IRF7)
AMJ: 102564189(IRF7)
PSS: 102462917(IRF7)
CMY: 102929901
CPIC: 101952035(IRF7)
ACS: 103278516(irf7)
PVT: 110074187(IRF7)
PBI: 103050794(IRF7)
PMUR: 107292762
TSR: 106546498(IRF7)
PMUA: 114599743(IRF7)
GJA: 107116862
XLA: 108713897(irf7.L)
XTR: 100496395(irf7)
NPR: 108786686
DRE: 393650(irf7)
CCAR: 109070803(irf7) 109074487
IPU: 108275163(irf7)
PHYP: 113529482(irf7)
AMEX: 103045043(irf7)
EEE: 113581332(irf7)
TRU: 101069060(irf7)
LCO: 104920456(irf7)
NCC: 104945359
MZE: 101476656(irf7)
ONL: 100706192(irf7)
XMA: 102220023(irf7)
XCO: 114135642(irf7)
PRET: 103466137(irf7)
CVG: 107085418(irf7)
NFU: 107388997(irf7)
KMR: 108239926(irf7)
ALIM: 106515646(irf7)
AOCE: 111584372(irf7)
CSEM: 103380393(irf7)
POV: 109624406(irf7)
LCF: 108875433(irf7)
SDU: 111228393(irf7)
SLAL: 111661782(irf7)
HCQ: 109530495
BPEC: 110169308
MALB: 109970775
SASA: 100192336(irf7) 100329194(irf7b)
ELS: 105018339(irf7)
SFM: 108942108
PKI: 111859397(irf7)
LCM: 102367315(IRF7)
CMK: 103189086(irf7)
RTP: 109935038
 » show all
Reference
  Authors
Marie I, Smith E, Prakash A, Levy DE
  Title
Phosphorylation-induced dimerization of interferon regulatory factor 7 unmasks DNA binding and a bipartite transactivation domain.
  Journal
Mol Cell Biol 20:8803-14 (2000)
DOI:10.1128/MCB.20.23.8803-8814.2000
Reference
PMID:9315633
  Authors
Zhang L, Pagano JS
  Title
IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency.
  Journal
Mol Cell Biol 17:5748-57 (1997)
DOI:10.1128/MCB.17.10.5748
  Sequence
[hsa:3665]
LinkDB

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