KEGG   ORTHOLOGY: K05414
Entry
K05414                      KO                                     

Name
IFNA
Definition
interferon alpha
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
ko05320  Autoimmune thyroid disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05414  IFNA; interferon alpha
   04151 PI3K-Akt signaling pathway
    K05414  IFNA; interferon alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05414  IFNA; interferon alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05414  IFNA; interferon alpha
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04621 NOD-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04622 RIG-I-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04623 Cytosolic DNA-sensing pathway
    K05414  IFNA; interferon alpha
   04650 Natural killer cell mediated cytotoxicity
    K05414  IFNA; interferon alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05414  IFNA; interferon alpha
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K05414  IFNA; interferon alpha
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05414  IFNA; interferon alpha
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05414  IFNA; interferon alpha
   05162 Measles
    K05414  IFNA; interferon alpha
   05164 Influenza A
    K05414  IFNA; interferon alpha
   05161 Hepatitis B
    K05414  IFNA; interferon alpha
   05160 Hepatitis C
    K05414  IFNA; interferon alpha
   05168 Herpes simplex virus 1 infection
    K05414  IFNA; interferon alpha
   05163 Human cytomegalovirus infection
    K05414  IFNA; interferon alpha
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05414  IFNA; interferon alpha
   05169 Epstein-Barr virus infection
    K05414  IFNA; interferon alpha
   05165 Human papillomavirus infection
    K05414  IFNA; interferon alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05414  IFNA; interferon alpha
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interferons
   K05414  IFNA; interferon alpha
Other DBs
GO: 0005132
Genes
HSA: 3439(IFNA1) 3440(IFNA2) 3441(IFNA4) 3442(IFNA5) 3443(IFNA6) 3444(IFNA7) 3445(IFNA8) 3446(IFNA10) 3447(IFNA13) 3448(IFNA14) 3449(IFNA16) 3451(IFNA17) 3452(IFNA21)
PTR: 473185(IFNA21) 473191 473193(IFNA14) 473195(IFNA5) 473196(IFNA6) 473197 473198(IFNA2) 473199(IFNA8) 741660 741747 741797 741978 742651 744748
PPS: 100967539 100968231 100968579 100968923 100969275 100969624 100970300 100970658(IFNA14) 100971675(IFNA6) 100972005 100972354(IFNA2) 100972691(IFNA8) 100973049 100995734(IFNA5)
GGO: 101137870(IFNA21) 101138981 101139336 101139713 101140412 101141176(IFNA6) 101141543 101141916(IFNA2) 101142301(IFNA8) 101142673 115935827 115935828 115935829 115935831 115935832 115935833 115935834
PON: 100432153 100432532(IFNA8) 100432906(IFNA2) 100433301 100434036(IFNA6) 100434796 100435169 100437034 100438149 100438871 100439978(IFNA21) 100443523 100445711 100459543 112134962
NLE: 100594907 100595254(IFNA8) 100595585(IFNA2) 100595932 100596272(IFNA6) 100596946 100597288 100597620 100597957 100598307
MCC: 106992322 106995851(IFNA6) 114672663 114672664 694631 709559(IFNA13) 709755(IFNA8) 709948(IFNA2) 710487 710528 710568 710654(IFNA10) 710751 710848 711088 711252(IFNA21)
MCF: 102115289(IFNA21) 102140303(IFNA1) 102140954(IFNA8) 102141352 102141744(IFNA13) 102142148(IFNA2) 102143043(IFNA6) 102144479(IFNA14) 102144833 102145208 102145962 102146717(IFNA4)
CSAB: 103219366 103219367(IFNA8) 103219368(IFNA2) 103219370 103219372 103219377 103219378 103219379 103219381
RRO: 104670273 104670275(IFNA8) 104670276 104670278(IFNA6) 104670280 104670290 104670292 104680728 115893964 115893973
MMU: 15962(Ifna1) 15964(Ifna11) 15965(Ifna2) 15967(Ifna4) 15968(Ifna5) 15969(Ifna6) 15970(Ifna7) 15972(Ifna9) 15974(Ifnab) 230396(Ifna13) 230398(Ifna16) 242517(Ifna15) 242519(Ifna12) 404549(Ifna14)
RNO: 100912314 298205(Ifna4) 298210(Ifna1) 298211(Ifna11) 298213(Ifna2) 500491(Ifna16l1) 502961(RGD1559679) 690894(Ifna5)
HGL: 101697163
FCA: 101081371 101088440 111557596 493648(IFNA8) 493653(IFNA7) 493840(IFNA5)
PTG: 102956750
BTA: 100329204(IFNAD) 100329206(IFNAG) 100329207(IFNAH) 100329210(INFAF) 100335490 281236(IFNAC) 510726(IFNA16) 515951(IFNAA) 517108 523244 618947 783912 787343
SSC: 100152100(IFN-ALPHA-13) 100152504(IFN-ALPHA-15) 100153325 100153661 100153724(IFN-ALPHA-8) 100154938(IFN-ALPHA-17) 100156561(IFN-ALPHA-10) 100156936 100157352(IFN-ALPHA-1) 100157735(IFN-ALPHA-16) 100157766(IFN-ALPHA-9) 100303758(IFN-ALPHA-5) 100310806(IFN-ALPHAOMEGA) 100737904 397686(IFNA1)
MYB: 106724769
MYD: 102766079
HAI: 109374670
OAA: 100075323(IFN3)
GGA: 100857744(IFNAL4) 100857947(IFNAL5) 100858177 100859032(IFNAL6) 101750245(IFNKL1) 396398(IFNA3) 768614(IFA3L)
MGP: 104915046
CJO: 107306162
NMEL: 110390131
ACYG: 106043723(IFNK) 106044139
LSR: 110470691
SCAN: 103819513 115485133(IFNK)
FAB: 101811547(IFNW1) 101815751
CCW: 104685212
FPG: 101915699(IFNW1)
FCH: 102059593 114016448(IFNK)
CLV: 102092004
ACUN: 113490068 113490202(IFNK)
PMUR: 107293819
TSR: 106542110
PMUA: 114588052(IFNK)
GJA: 107108155
DRE: 100126803(ifnphi3) 360134(ifnphi1)
PRET: 108167267
ALIM: 106535558
SDU: 111220091
BPEC: 110154330
 » show all
Reference
PMID:6157600
  Authors
Mantei N, Schwarzstein M, Streuli M, Panem S, Nagata S, Weissmann C
  Title
The nucleotide sequence of a cloned human leukocyte interferon cDNA.
  Journal
Gene 10:1-10 (1980)
DOI:10.1016/0378-1119(80)90137-7
  Sequence
[hsa:3439]
LinkDB

KEGG   ORTHOLOGY: K05415
Entry
K05415                      KO                                     

Name
IFNB
Definition
interferon beta
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04668  TNF signaling pathway
ko05131  Shigellosis
ko05135  Yersinia infection
ko05142  Chagas disease
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05415  IFNB; interferon beta
   04668 TNF signaling pathway
    K05415  IFNB; interferon beta
   04151 PI3K-Akt signaling pathway
    K05415  IFNB; interferon beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05415  IFNB; interferon beta
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05415  IFNB; interferon beta
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04621 NOD-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04622 RIG-I-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04623 Cytosolic DNA-sensing pathway
    K05415  IFNB; interferon beta
   04650 Natural killer cell mediated cytotoxicity
    K05415  IFNB; interferon beta
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05415  IFNB; interferon beta
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05415  IFNB; interferon beta
   05135 Yersinia infection
    K05415  IFNB; interferon beta
   05152 Tuberculosis
    K05415  IFNB; interferon beta
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05415  IFNB; interferon beta
   05162 Measles
    K05415  IFNB; interferon beta
   05164 Influenza A
    K05415  IFNB; interferon beta
   05161 Hepatitis B
    K05415  IFNB; interferon beta
   05160 Hepatitis C
    K05415  IFNB; interferon beta
   05168 Herpes simplex virus 1 infection
    K05415  IFNB; interferon beta
   05163 Human cytomegalovirus infection
    K05415  IFNB; interferon beta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05415  IFNB; interferon beta
   05169 Epstein-Barr virus infection
    K05415  IFNB; interferon beta
   05165 Human papillomavirus infection
    K05415  IFNB; interferon beta
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K05415  IFNB; interferon beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05415  IFNB; interferon beta
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interferons
   K05415  IFNB; interferon beta
Other DBs
GO: 0005132
Genes
HSA: 3456(IFNB1)
PTR: 473183(IFNB1)
PPS: 100995851(IFNB1)
GGO: 101137136(IFNB1)
PON: 100441074(IFNB1)
NLE: 100598986(IFNB1)
MCC: 711414(IFNB1)
MCF: 102115670(IFNB1)
CSAB: 103219383(IFNB1)
RRO: 104670295(IFNB1)
RBB: 108538565(IFNB1)
CJC: 100388391(IFNB1)
SBQ: 101035681(IFNB1)
MMU: 15977(Ifnb1)
MCAL: 110293791(Ifnb1)
MPAH: 110323346(Ifnb1)
RNO: 24481(Ifnb1)
MUN: 110541303(Ifnb1)
CGE: 103160615(Ifnb1)
NGI: 103743951(Ifnb1) 103746144
HGL: 101699042(Ifnb1) 101723869
OCU: 100342931(IFNB1)
TUP: 102493858(IFNB1)
CFA: 481558(IFNB1)
VVP: 112921940(IFNB1)
AML: 100476556(IFNB1)
UMR: 103662150(IFNB1)
UAH: 113260295(IFNB1)
ORO: 101374900(IFNB1)
ELK: 111156577
FCA: 493849(IFNB1)
PTG: 102960421(IFNB1)
PPAD: 109247124(IFNB1)
AJU: 106971145(IFNB1)
SSC: 445459(IFNB1)
CFR: 102513411(IFNB1)
CDK: 105095933(IFNB1)
BACU: 103011926
LVE: 103073772
OOR: 101289058(IFNB1)
DLE: 111174560(IFNB1)
PCAD: 102990155(IFNB1)
MYB: 102261905(IFNB1)
MYD: 102765800(IFNB1)
MNA: 107531433(IFNB1)
HAI: 109396418(IFNB1)
DRO: 112300024(IFNB1)
PALE: 102890512(IFNB1)
RAY: 107518589(IFNB1)
MJV: 108402531(IFNB1)
LAV: 100666438(IFNB1)
TMU: 101349610
MDO: 100021258(IFNB1)
SHR: 100914443
OAA: 100082925(IFNB1)
GGA: 554219(IFNW1)
MGP: 109363864
NMEL: 110390553
ACYG: 106045178
LSR: 110484216
SCAN: 108962800
FPG: 101921672
NNI: 104017595
 » show all
Reference
  Authors
Ohno S, Taniguchi T
  Title
Structure of a chromosomal gene for human interferon beta.
  Journal
Proc Natl Acad Sci U S A 78:5305-9 (1981)
DOI:10.1073/pnas.78.9.5305
  Sequence
[hsa:3456]
LinkDB

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