KEGG   ORTHOLOGY: K05438
Entry
K05438                      KO                                     

Name
GH
Definition
growth hormone
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04935  Growth hormone synthesis, secretion and action
Disease
H00254  Growth hormone deficiency
H02035  Isolated growth hormone deficiency
H02039  Kowarski syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05438  GH; growth hormone
   04151 PI3K-Akt signaling pathway
    K05438  GH; growth hormone
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05438  GH; growth hormone
   04060 Cytokine-cytokine receptor interaction
    K05438  GH; growth hormone
 09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    K05438  GH; growth hormone
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05438  GH; growth hormone
Cytokines and growth factors [BR:ko04052]
 Cytokines
  CSF and other factors
   K05438  GH; growth hormone
Genes
HSA: 1442(CSH1) 1443(CSH2) 2688(GH1) 2689(GH2)
PTR: 100505396(GH2) 112206073 449574(PL-D) 454774(GH1)
PPS: 100971425(GH1) 100972442(GH2) 100973020 100983900 100985912
GGO: 101124194(GH1) 101125803 101126399(GH2) 101126984 115934631 115934632
PON: 100446663 100447767 100448861(GH1) 103892869
NLE: 100579700 100580921 100582356 100585742 115830369 115830462
MCC: 114669732 114669819 114673168 114673169 700885(GHV) 717562(CSH2) 718116(CSH4) 718135(CSH3) 718156(GH1) 718474 735307
MCF: 102139443(CSH2) 102141100(CSH4) 102143728(GH1) 102973054(CSH3) 102973055(GHV)
CSAB: 103243211 103243213 103243214 103243843 108449889
RRO: 104675453 104675456 104675458 104675500 104675501 104675502
CJC: 100392546(GH1) 100412128(GH1P5) 100412471(GH1P6)
MMU: 14599(Gh)
MCAL: 110305672(Gh1)
MPAH: 110332223
RNO: 24391(Gh1)
MUN: 110547057
CGE: 100770534(Gh1)
NGI: 103744748
HGL: 101712254(Gh1)
CCAN: 109700526(Gh1)
OCU: 100356068(GH1)
CFA: 403795(GH1)
VVP: 112920600
AML: 100471532(GH1)
UMR: 103665901
UAH: 113265156
ORO: 101371706
ELK: 111158084
FCA: 493931(GH1)
PTG: 102954011(GH1)
PPAD: 109277181
AJU: 106978672
BTA: 280804(GH1)
BOM: 102271788
BIU: 109574543
BBUB: 102406287(GH)
CHX: 100861230(GH1) 108638229(GH)
OAS: 114116958 443329(GH)
SSC: 396884(GH1)
CFR: 102518081
CDK: 105090400
BACU: 103018096(GH1)
LVE: 103077460(GH1)
OOR: 101289821
DLE: 111182618
PCAD: 102979127
ECB: 100034180(GH1)
EPZ: 103549756
EAI: 106835535
MYB: 102242921
MYD: 102761658
MNA: 107531064
HAI: 109380250
DRO: 112316514
PALE: 102888823
RAY: 107502287(GH1)
MJV: 108403155
LAV: 100662962
TMU: 101353229
MDO: 554243(GH1)
SHR: 100922992
PCW: 110215837
OAA: 114815005(GH1)
GGA: 378781(GH)
MGP: 100303681
CJO: 107325039
NMEL: 110388393
APLA: 101790997(GH1)
LSR: 110471658 110479562(GH1)
FAB: 101810386(GH1) 101816810
ETL: 114069211 114070629(GH1)
FPG: 101911583(GH1)
FCH: 102050341(GH1)
EGZ: 104131083
NNI: 104012273
ACUN: 113489170
PADL: 103926084
AAM: 106486447
ASN: 102387497(GH1)
AMJ: 102576793
PSS: 102460820
CMY: 102937830(GH1)
CPIC: 101940316(GH1)
ACS: 100555670
PVT: 110081378
PBI: 103053760
PMUR: 114923910
TSR: 106550136
PMUA: 114582042(GH1)
GJA: 107114953(GH1)
XLA: 373617(gh1.S) 378580(gh1-like.L) 399154(gh1.L)
XTR: 100490878(gh2) 100492540(gh1)
NPR: 108790547
DRE: 407639(gh1) 572522(smtla)
IPU: 100304502(sl) 100305005(gh)
EEE: 113587837
NCC: 104960967
CMK: 103187720
RTP: 109910501
 » show all
Reference
  Authors
Clayton PE, Banerjee I, Murray PG, Renehan AG
  Title
Growth hormone, the insulin-like growth factor axis, insulin and cancer risk.
  Journal
Nat Rev Endocrinol 7:11-24 (2011)
DOI:10.1038/nrendo.2010.171
Reference
PMID:3379057
  Authors
Cooke NE, Ray J, Emery JG, Liebhaber SA
  Title
Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins.
  Journal
J Biol Chem 263:9001-6 (1988)
  Sequence
[hsa:2688 2689]
LinkDB

KEGG   ORTHOLOGY: K05439
Entry
K05439                      KO                                     

Name
PRL
Definition
prolactin
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04917  Prolactin signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05439  PRL; prolactin
   04151 PI3K-Akt signaling pathway
    K05439  PRL; prolactin
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05439  PRL; prolactin
   04060 Cytokine-cytokine receptor interaction
    K05439  PRL; prolactin
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05439  PRL; prolactin
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05439  PRL; prolactin
Cytokines and growth factors [BR:ko04052]
 Cytokines
  CSF and other factors
   K05439  PRL; prolactin
Genes
HSA: 5617(PRL)
PTR: 462468(PRL)
PPS: 100970831(PRL)
GGO: 101141749(PRL)
PON: 100450466(PRL)
NLE: 100596407(PRL)
MCC: 707052(PRL)
MCF: 102133150(PRL)
CSAB: 103222073(PRL)
RRO: 104654795(PRL)
RBB: 108530294(PRL)
CJC: 100413643(PRL)
SBQ: 101037800(PRL)
MMU: 19109(Prl) 19111(Prl6a1) 28078(Prl5a1)
RNO: 171556(Prl5a1) 24657(Prl6a1) 24683(Prl)
OCU: 100009394(PRL)
TUP: 102500251(PRL)
CFA: 488241(PRL)
VVP: 112920503(PRL)
AML: 100481524(PRL)
UMR: 103678373(PRL)
UAH: 113264523(PRL)
ORO: 101378550(PRL)
ELK: 111138630
FCA: 751517(PRL)
PTG: 102970648(PRL)
PPAD: 109252661(PRL)
AJU: 106987609(PRL)
BTA: 100298767 280901(PRL) 281097(CSH2) 281429(PRP1) 281430(PRP3) 282007(PRP14) 404081(PRP6) 406200(PRP4) 497206(PRP-VII) 519859(PRP9) 613971(PRP8) 790470(PRP2)
SSC: 396965(PRL)
CFR: 102513256(PRL)
CDK: 105089122(PRL)
BACU: 103005353(PRL)
LVE: 103068298
OOR: 101289965(PRL)
DLE: 111181274(PRL)
PCAD: 102976160(PRL)
ECB: 100034034(PRL)
EPZ: 103555098(PRL)
EAI: 106847015(PRL)
MYB: 102261680(PRL)
MYD: 102773602(PRL)
MNA: 107533698(PRL)
HAI: 109381635(PRL)
DRO: 112309295(PRL)
PALE: 102887064(PRL)
RAY: 107514304(PRL)
MJV: 108385400(PRL)
LAV: 100654812(PRL)
TMU: 101346160
MDO: 100017831(PRL)
SHR: 100932842(PRL)
PCW: 110208793(PRL)
OAA: 100083427(PRL)
GGA: 396453(PRL) 417800(PRLL)
MGP: 100303694(PRL) 100539893
CJO: 107309721 107309735(PRL)
NMEL: 110392634 110394973(PRL)
APLA: 101793561 101793643(PRL)
ACYG: 106038354(PRL) 106045491
TGU: 100228929(PRL) 101232981
SCAN: 103819399(PRL) 103820421
GFR: 102032711(PRL) 102040600
FAB: 101807433(PRL) 101820588
PHI: 102099089(PRL) 102100779
PMAJ: 107198339(PRL) 107204650
CCAE: 111923970(PRL) 111932116
CCW: 104691439(PRL) 104698455
ETL: 114061970 114068494(PRL)
FPG: 101917226(PRL) 101923021
FCH: 102047707 102051915(PRL)
CLV: 102090354(PRL) 102092998
EGZ: 104125480(PRL)
NNI: 104021796(PRL)
ACUN: 113476487(PRL)
PADL: 103919057(PRL)
AAM: 106483309(PRL)
ASN: 102380918(PRL)
AMJ: 102574258(PRL)
PSS: 102450009(PRL) 102456053
CMY: 102931458 102944759(Prolactin)
CPIC: 101940655 101943700(PRL)
ACS: 100561954(prl)
PVT: 110072918(PRL) 110079980
PBI: 103057526(PRL)
PMUR: 107289607(PRL)
TSR: 106547056(PRL)
PMUA: 114601367(PRL) 114605534
GJA: 107125531(PRL)
XLA: 100310824(prl.2.L) 108695906 108697263 446320(prl.1.L) 734391(prl.1.S)
NPR: 108792905(PRL) 108801639
DRE: 799612(prl2)
IPU: 108279639 108280547(prl)
TRU: 101062490(prl) 101065978 778002(prl)
OLA: 101172582 101174239(prl)
PRET: 103459740(prl) 103468295
MALB: 109951456
CMK: 103176856(prl)
RTP: 109933217(prl)
 » show all
Reference
  Authors
Trott JF, Schennink A, Petrie WK, Manjarin R, VanKlompenberg MK, Hovey RC
  Title
Triennial Lactation Symposium: Prolactin: The multifaceted potentiator of mammary growth and function.
  Journal
J Anim Sci 90:1674-86 (2012)
DOI:10.2527/jas.2011-4682
LinkDB

KEGG   ORTHOLOGY: K05418
Entry
K05418                      KO                                     

Name
OSM
Definition
oncostatin M
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05418  OSM; oncostatin M
   04151 PI3K-Akt signaling pathway
    K05418  OSM; oncostatin M
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05418  OSM; oncostatin M
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05418  OSM; oncostatin M
Cytokines and growth factors [BR:ko04052]
 Cytokines
  CSF and other factors
   K05418  OSM; oncostatin M
Other DBs
GO: 0005147
Genes
HSA: 5008(OSM)
PTR: 736338(OSM)
PPS: 100971653(OSM)
GGO: 101138490(OSM)
PON: 100448170(OSM)
NLE: 100603259(OSM)
MCC: 717994(OSM)
MCF: 102128264(OSM)
CSAB: 103223157(OSM)
RRO: 104659494(OSM)
RBB: 108517598(OSM)
CJC: 100387903(OSM)
SBQ: 101043909(OSM)
MMU: 18413(Osm)
MCAL: 110306250(Osm)
MPAH: 110330998(Osm)
RNO: 289747(Osm)
MUN: 110557889(Osm)
CGE: 100758591(Osm)
NGI: 103740483(Osm)
HGL: 101705496(Osm)
CCAN: 109697282(Osm)
OCU: 100342491(OSM)
TUP: 102469110(OSM)
CFA: 611921(OSM)
VVP: 112909849(OSM)
AML: 100483167(OSM)
UMR: 103681110(OSM)
UAH: 113245027(OSM)
ORO: 101366093(OSM)
ELK: 111160020
FCA: 101094379(OSM)
PTG: 102967884(OSM)
PPAD: 109253577(OSM)
AJU: 106983325(OSM)
BTA: 319086(OSM)
BOM: 102271854(OSM)
BIU: 109570838(OSM)
BBUB: 102390598(OSM)
CHX: 102188790(OSM)
OAS: 101122466(OSM)
SSC: 100152038(OSM)
CFR: 102518444(OSM)
CDK: 105099450(OSM)
BACU: 103016655(OSM)
LVE: 103072416(OSM)
OOR: 101277557(OSM)
DLE: 111162704(OSM)
PCAD: 102974009(OSM)
ECB: 100064031(OSM)
EPZ: 103548080(OSM)
EAI: 106827183(OSM)
MYB: 102259125(OSM)
MYD: 102767198(OSM)
MNA: 107526227(OSM)
HAI: 109383043(OSM)
DRO: 112310359(OSM)
PALE: 102889450(OSM)
RAY: 107505411(OSM)
MJV: 108396879(OSM)
LAV: 100660616(OSM)
TMU: 101357379
MDO: 103094214(OSM)
SHR: 105749464
PCW: 110215344(OSM)
OAA: 114806198
PHI: 102114426(OSM)
PMAJ: 107211524
FCH: 114017528(OSM)
PVT: 110069935
PMUR: 114922669
ONL: 100695333
HCQ: 109517151
ELS: 105014914
SFM: 108932857
 » show all
Reference
  Authors
Okaya A, Kitanaka J, Kitanaka N, Satake M, Kim Y, Terada K, Sugiyama T, Takemura M, Fujimoto J, Terada N, Miyajima A, Tsujimura T
  Title
Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes.
  Journal
Am J Pathol 166:709-19 (2005)
DOI:10.1016/S0002-9440(10)62292-4
  Sequence
[rno:289747]
Reference
  Authors
White UA, Stephens JM
  Title
The gp130 receptor cytokine family: regulators of adipocyte development and function.
  Journal
Curr Pharm Des 17:340-6 (2011)
DOI:10.2174/138161211795164202
LinkDB

KEGG   ORTHOLOGY: K05429
Entry
K05429                      KO                                     

Name
IL2
Definition
interleukin 2
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04151  PI3K-Akt signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04672  Intestinal immune network for IgA production
ko04940  Type I diabetes mellitus
ko05135  Yersinia infection
ko05142  Chagas disease
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
ko05320  Autoimmune thyroid disease
ko05321  Inflammatory bowel disease
ko05330  Allograft rejection
ko05332  Graft-versus-host disease
Disease
H00084  Graft-versus-host disease
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05429  IL2; interleukin 2
   04151 PI3K-Akt signaling pathway
    K05429  IL2; interleukin 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05429  IL2; interleukin 2
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05429  IL2; interleukin 2
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K05429  IL2; interleukin 2
   04660 T cell receptor signaling pathway
    K05429  IL2; interleukin 2
   04658 Th1 and Th2 cell differentiation
    K05429  IL2; interleukin 2
   04659 Th17 cell differentiation
    K05429  IL2; interleukin 2
   04672 Intestinal immune network for IgA production
    K05429  IL2; interleukin 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05429  IL2; interleukin 2
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K05429  IL2; interleukin 2
   05321 Inflammatory bowel disease
    K05429  IL2; interleukin 2
   05330 Allograft rejection
    K05429  IL2; interleukin 2
   05332 Graft-versus-host disease
    K05429  IL2; interleukin 2
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K05429  IL2; interleukin 2
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05429  IL2; interleukin 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05429  IL2; interleukin 2
   05171 Coronavirus disease - COVID-19
    K05429  IL2; interleukin 2
   05162 Measles
    K05429  IL2; interleukin 2
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K05429  IL2; interleukin 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05429  IL2; interleukin 2
   00536 Glycosaminoglycan binding proteins
    K05429  IL2; interleukin 2
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K05429  IL2; interleukin 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K05429  IL2; interleukin 2
Other DBs
GO: 0005134
Genes
HSA: 3558(IL2)
PTR: 461472(IL2)
PPS: 100984780(IL2)
GGO: 101132394(IL2)
PON: 100455248(IL2)
NLE: 100591126(IL2)
MCC: 708017(IL2)
MCF: 102129830(IL2)
CSAB: 103236209(IL2)
RRO: 104661748(IL2)
RBB: 108515581(IL2)
CJC: 100386848(IL2)
SBQ: 101028427(IL2)
MMU: 16183(Il2)
MCAL: 110291180(Il2)
MPAH: 110320556(Il2)
RNO: 116562(Il2)
MUN: 110545874(Il2) 110560079
CGE: 100755773(Il2)
NGI: 103746951(Il2)
HGL: 101720581(Il2)
CCAN: 109691916(Il2)
OCU: 100302458(IL2)
TUP: 102478615(IL2)
CFA: 403989(IL2)
VVP: 112933619(IL2)
AML: 100480862(IL2)
UMR: 103661804(IL2)
UAH: 113255635(IL2)
ORO: 101386196(IL2)
ELK: 111154869
FCA: 751114(IL2)
PTG: 102957506(IL2)
PPAD: 109248906(IL2)
AJU: 106977102(IL2)
BTA: 280822(IL2)
BOM: 102272426(IL2)
BIU: 109571028(IL2)
BBUB: 102395421(IL2)
CHX: 102183089(IL2)
OAS: 443401(IL2)
SSC: 396868(IL2)
CFR: 102514894(IL2)
CDK: 105093664(IL2)
BACU: 103017896(IL2)
LVE: 103071508(IL2)
OOR: 101274648(IL2)
DLE: 111186150(IL2)
PCAD: 102990654(IL2)
ECB: 100034204(IL2)
EPZ: 103557874(IL2)
EAI: 106834088(IL2)
MYB: 102246940(IL2)
MYD: 102773629(IL2)
MNA: 107529760(IL2)
HAI: 109395924(IL2)
DRO: 112312503(IL2)
PALE: 102895516(IL2)
RAY: 107505383(IL2)
MJV: 108383567(IL2)
LAV: 100656398(IL2)
TMU: 101360180
MDO: 100619184(IL2)
SHR: 100935068
PCW: 110223001
OAA: 114815476
GGA: 373958(IL2)
MGP: 100303688
APLA: 101794925(IL-2)
FAB: 101807567(IL2)
CLV: 102091580
 » show all
Reference
PMID:6312994
  Authors
Maeda S, Nishino N, Obaru K, Mita S, Nomiyama H, Shimada K, Fujimoto K, Teranishi T, Hirano T, Onoue K
  Title
Cloning of interleukin 2 mRNAs from human tonsils.
  Journal
Biochem Biophys Res Commun 115:1040-7 (1983)
DOI:10.1016/S0006-291X(83)80040-0
  Sequence
[hsa:3558]
LinkDB

KEGG   ORTHOLOGY: K04736
Entry
K04736                      KO                                     

Name
IL3
Definition
interleukin 3
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04210  Apoptosis
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04664  Fc epsilon RI signaling pathway
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05221  Acute myeloid leukemia
ko05310  Asthma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K04736  IL3; interleukin 3
   04151 PI3K-Akt signaling pathway
    K04736  IL3; interleukin 3
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04736  IL3; interleukin 3
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04736  IL3; interleukin 3
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04736  IL3; interleukin 3
   04664 Fc epsilon RI signaling pathway
    K04736  IL3; interleukin 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04736  IL3; interleukin 3
   05202 Transcriptional misregulation in cancer
    K04736  IL3; interleukin 3
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K04736  IL3; interleukin 3
  09163 Immune disease
   05310 Asthma
    K04736  IL3; interleukin 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K04736  IL3; interleukin 3
   00536 Glycosaminoglycan binding proteins
    K04736  IL3; interleukin 3
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K04736  IL3; interleukin 3
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K04736  IL3; interleukin 3
Other DBs
GO: 0005135
Genes
HSA: 3562(IL3)
PTR: 471626(IL3)
PPS: 100967294(IL3)
GGO: 101132913(IL3)
PON: 100447057(IL3)
NLE: 100593178(IL3)
MCC: 706946(IL3)
MCF: 102118362(IL3)
CSAB: 103244501(IL3)
RRO: 104659849(IL3)
RBB: 108521978(IL3)
CJC: 100410529(IL3)
SBQ: 101043897(IL3)
MMU: 16187(Il3)
MCAL: 110306329
MPAH: 110332758
RNO: 24495(Il3)
MUN: 110561719
CFA: 481497(IL3)
AML: 100473242
UMR: 103670504(IL3)
UAH: 113261704
ELK: 111140799
FCA: 111560806
PTG: 107180157
PPAD: 109250815(IL3)
AJU: 113604567(IL3)
BTA: 280823(IL3)
BOM: 102275760(IL3)
BIU: 109561219
BBUB: 102413882(IL3)
CHX: 102190507(IL3)
OAS: 443438(IL3)
BACU: 103019984(IL3)
LVE: 103088921(IL3)
OOR: 101275202
DLE: 111182348
PCAD: 102973496
EPZ: 103556577(IL3)
EAI: 106841027(IL3)
HAI: 109382577(IL3)
DRO: 112301616(IL3)
PALE: 102896574
RAY: 107497018
MJV: 108392856
LAV: 111750521
 » show all
Reference
  Authors
Barreda DR, Hanington PC, Belosevic M
  Title
Regulation of myeloid development and function by colony stimulating factors.
  Journal
Dev Comp Immunol 28:509-54 (2004)
DOI:10.1016/j.dci.2003.09.010
Reference
  Authors
He WY, Lan Y, Yao HY, Li Z, Wang XY, Li XS, Zhang JY, Zhang Y, Liu B, Mao N
  Title
Interleukin-3 promotes hemangioblast development in mouse aorta-gonad-mesonephros region.
  Journal
Haematologica 95:875-83 (2010)
DOI:10.3324/haematol.2009.014241
  Sequence
[mmu:16187]
LinkDB

KEGG   ORTHOLOGY: K05405
Entry
K05405                      KO                                     

Name
IL6
Definition
interleukin 6
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko01523  Antifolate resistance
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04066  HIF-1 signaling pathway
ko04068  FoxO signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04625  C-type lectin receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04657  IL-17 signaling pathway
ko04659  Th17 cell differentiation
ko04668  TNF signaling pathway
ko04672  Intestinal immune network for IgA production
ko04931  Insulin resistance
ko04932  Non-alcoholic fatty liver disease
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05010  Alzheimer disease
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05130  Pathogenic Escherichia coli infection
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05135  Yersinia infection
ko05142  Chagas disease
ko05143  African trypanosomiasis
ko05144  Malaria
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05321  Inflammatory bowel disease
ko05323  Rheumatoid arthritis
ko05332  Graft-versus-host disease
ko05410  Hypertrophic cardiomyopathy
Disease
H00084  Graft-versus-host disease
H01479  Castleman disease
H01672  Juvenile idiopathic arthritis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05405  IL6; interleukin 6
   04668 TNF signaling pathway
    K05405  IL6; interleukin 6
   04066 HIF-1 signaling pathway
    K05405  IL6; interleukin 6
   04068 FoxO signaling pathway
    K05405  IL6; interleukin 6
   04151 PI3K-Akt signaling pathway
    K05405  IL6; interleukin 6
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05405  IL6; interleukin 6
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05405  IL6; interleukin 6
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    K05405  IL6; interleukin 6
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05405  IL6; interleukin 6
   04620 Toll-like receptor signaling pathway
    K05405  IL6; interleukin 6
   04621 NOD-like receptor signaling pathway
    K05405  IL6; interleukin 6
   04623 Cytosolic DNA-sensing pathway
    K05405  IL6; interleukin 6
   04625 C-type lectin receptor signaling pathway
    K05405  IL6; interleukin 6
   04659 Th17 cell differentiation
    K05405  IL6; interleukin 6
   04657 IL-17 signaling pathway
    K05405  IL6; interleukin 6
   04672 Intestinal immune network for IgA production
    K05405  IL6; interleukin 6
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05405  IL6; interleukin 6
   05202 Transcriptional misregulation in cancer
    K05405  IL6; interleukin 6
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05405  IL6; interleukin 6
   05321 Inflammatory bowel disease
    K05405  IL6; interleukin 6
   05332 Graft-versus-host disease
    K05405  IL6; interleukin 6
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05405  IL6; interleukin 6
   05020 Prion disease
    K05405  IL6; interleukin 6
   05022 Pathways of neurodegeneration - multiple diseases
    K05405  IL6; interleukin 6
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K05405  IL6; interleukin 6
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K05405  IL6; interleukin 6
   04931 Insulin resistance
    K05405  IL6; interleukin 6
   04933 AGE-RAGE signaling pathway in diabetic complications
    K05405  IL6; interleukin 6
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05405  IL6; interleukin 6
   05132 Salmonella infection
    K05405  IL6; interleukin 6
   05135 Yersinia infection
    K05405  IL6; interleukin 6
   05133 Pertussis
    K05405  IL6; interleukin 6
   05134 Legionellosis
    K05405  IL6; interleukin 6
   05152 Tuberculosis
    K05405  IL6; interleukin 6
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05405  IL6; interleukin 6
   05161 Hepatitis B
    K05405  IL6; interleukin 6
   05171 Coronavirus disease - COVID-19
    K05405  IL6; interleukin 6
   05164 Influenza A
    K05405  IL6; interleukin 6
   05162 Measles
    K05405  IL6; interleukin 6
   05168 Herpes simplex virus 1 infection
    K05405  IL6; interleukin 6
   05163 Human cytomegalovirus infection
    K05405  IL6; interleukin 6
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05405  IL6; interleukin 6
   05169 Epstein-Barr virus infection
    K05405  IL6; interleukin 6
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K05405  IL6; interleukin 6
   05144 Malaria
    K05405  IL6; interleukin 6
   05142 Chagas disease
    K05405  IL6; interleukin 6
   05143 African trypanosomiasis
    K05405  IL6; interleukin 6
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05405  IL6; interleukin 6
   01523 Antifolate resistance
    K05405  IL6; interleukin 6
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05405  IL6; interleukin 6
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K05405  IL6; interleukin 6
Other DBs
GO: 0005138
Genes
HSA: 3569(IL6)
PTR: 463288(IL6)
PPS: 100967827(IL6)
GGO: 101151687(IL6)
PON: 100453941(IL6)
NLE: 100586527(IL6)
MCC: 705819(IL6)
MCF: 102138971(IL6)
CSAB: 103226390(IL6)
RRO: 104675233(IL6)
RBB: 108529326(IL6)
CJC: 100393440(IL6)
SBQ: 101034757(IL6)
MMU: 16193(Il6)
MCAL: 110295330(Il6)
MPAH: 110317140(Il6)
RNO: 24498(Il6)
MUN: 110539463(Il6)
CGE: 100689186(Il6)
NGI: 103740849(Il6)
HGL: 101702602(Il6)
CCAN: 109679557(Il6)
OCU: 100008733(IL6)
CFA: 403985(IL6)
VVP: 112915865(IL6)
AML: 100477151(IL6)
UMR: 103658871(IL6)
UAH: 113261280(IL6)
ORO: 101377851(IL6)
ELK: 111147365
FCA: 493687(IL6)
PTG: 102968780(IL6)
PPAD: 109263814(IL6)
AJU: 106982277(IL6)
BTA: 280826(IL6)
BOM: 102287919(IL6)
BIU: 109558077(IL6)
BBUB: 102415101(IL6)
CHX: 100860785(IL6)
OAS: 443406(IL6)
SSC: 399500(IL6)
CFR: 102515320(IL6)
CDK: 105095065(IL6)
BACU: 103008558(IL6)
LVE: 103081545(IL6)
OOR: 101281783(IL6)
DLE: 111181978(IL6)
PCAD: 102980126(IL6)
ECB: 100034196(IL6)
EPZ: 103561141(IL6)
EAI: 106824372(IL6)
MYB: 102243367(IL6)
MYD: 102760336(IL6)
MNA: 107540295(IL6)
HAI: 109387871(IL6)
DRO: 112306851(IL6)
PALE: 102895746(IL6)
RAY: 107518120(IL6)
MJV: 108398622(IL6)
LAV: 100660846(IL6)
TMU: 101351590
MDO: 103104339(IL6)
SHR: 105750762(IL6)
PCW: 110213115(IL6)
OAA: 100083298(IL6)
GGA: 395337(IL6)
MGP: 100548599(IL6)
CJO: 107309150(IL6)
NMEL: 110394224(IL6)
APLA: 101798321(IL6)
ACYG: 106030150(IL6)
TGU: 100220682(IL6)
LSR: 110474585(IL6)
SCAN: 103813132(IL6)
GFR: 102040265(IL6)
FAB: 101806545(IL6)
PHI: 102109522(IL6)
PMAJ: 107215587(IL6)
CCAE: 111924309(IL6)
CCW: 104689316(IL6)
ETL: 114063967(IL6)
FPG: 101911163(IL6)
FCH: 102047657(IL6)
CLV: 102097240(IL6)
EGZ: 104126108(IL6)
NNI: 104013985(IL6)
ACUN: 113476314(IL6)
PADL: 103918452(IL6)
AAM: 106483538(IL6)
ASN: 102377828(IL6)
AMJ: 102567649(IL6)
PSS: 102450313(IL6)
CMY: 102935916(IL6)
CPIC: 101951588(IL6)
ACS: 103279135(il6)
PVT: 110073207(IL6)
PBI: 103067562(IL6)
PMUR: 107282781(IL6)
GJA: 107116125(IL6)
XLA: 108718487
XTR: 100493927(il6)
NPR: 108797293
DRE: 100885851(il6)
SRX: 107755962
CCAR: 109055884
IPU: 108257494(il6)
AMEX: 111191914
TRU: 503562(il-6)
NCC: 104965305
MZE: 101476515
ONL: 102077017
NFU: 107383629
AOCE: 111573783
CSEM: 103394639
POV: 109631714
LCF: 108897837
SDU: 111223243
SLAL: 111659317
HCQ: 109513551
BPEC: 110167338
MALB: 109963919
SASA: 106570581(IL6) 106588787
OTW: 112235861
ELS: 105012469
SFM: 108933304(il6)
PKI: 111846921(il6)
LCM: 102347088(IL6)
CMK: 103185302 103185303(il6)
RTP: 109925317(il6) 109925335
 » show all
Reference
  Authors
Fonseca JE, Santos MJ, Canhao H, Choy E
  Title
Interleukin-6 as a key player in systemic inflammation and joint destruction.
  Journal
Autoimmun Rev 8:538-42 (2009)
DOI:10.1016/j.autrev.2009.01.012
Reference
PMID:3500852
  Authors
Yasukawa K, Hirano T, Watanabe Y, Muratani K, Matsuda T, Nakai S, Kishimoto T
  Title
Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.
  Journal
EMBO J 6:2939-45 (1987)
DOI:10.1002/j.1460-2075.1987.tb02598.x
  Sequence
[hsa:3569]
LinkDB

KEGG   ORTHOLOGY: K05430
Entry
K05430                      KO                                     

Name
IL4
Definition
interleukin 4
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04657  IL-17 signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko04672  Intestinal immune network for IgA production
ko05140  Leishmaniasis
ko05200  Pathways in cancer
ko05310  Asthma
ko05320  Autoimmune thyroid disease
ko05321  Inflammatory bowel disease
ko05330  Allograft rejection
Disease
H00079  Asthma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05430  IL4; interleukin 4
   04151 PI3K-Akt signaling pathway
    K05430  IL4; interleukin 4
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05430  IL4; interleukin 4
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05430  IL4; interleukin 4
   04660 T cell receptor signaling pathway
    K05430  IL4; interleukin 4
   04658 Th1 and Th2 cell differentiation
    K05430  IL4; interleukin 4
   04659 Th17 cell differentiation
    K05430  IL4; interleukin 4
   04657 IL-17 signaling pathway
    K05430  IL4; interleukin 4
   04664 Fc epsilon RI signaling pathway
    K05430  IL4; interleukin 4
   04672 Intestinal immune network for IgA production
    K05430  IL4; interleukin 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05430  IL4; interleukin 4
  09163 Immune disease
   05310 Asthma
    K05430  IL4; interleukin 4
   05320 Autoimmune thyroid disease
    K05430  IL4; interleukin 4
   05321 Inflammatory bowel disease
    K05430  IL4; interleukin 4
   05330 Allograft rejection
    K05430  IL4; interleukin 4
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K05430  IL4; interleukin 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05430  IL4; interleukin 4
   00536 Glycosaminoglycan binding proteins
    K05430  IL4; interleukin 4
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K05430  IL4; interleukin 4
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K05430  IL4; interleukin 4
Other DBs
GO: 0005136
Genes
HSA: 3565(IL4)
PTR: 449565(IL4)
PPS: 100988878(IL4)
GGO: 101140015(IL4)
PON: 100451705(IL4)
NLE: 100597165(IL4)
MCC: 574281(IL4)
MCF: 107130068(IL4)
CSAB: 103244520(IL4)
RRO: 104659834(IL4)
RBB: 108529583(IL4)
CJC: 100406536(IL4)
SBQ: 101038267(IL4)
MMU: 16189(Il4)
MCAL: 110306003(Il4)
MPAH: 110332760(Il4)
RNO: 287287(Il4)
MUN: 110548759(Il4)
CGE: 100755642(Il4)
NGI: 103747047(Il4)
HGL: 101706414(Il4)
CCAN: 109694185(Il4)
OCU: 100302454(IL4)
TUP: 102483778(IL4)
CFA: 403785(IL4)
VVP: 112917033(IL4)
AML: 100482473(IL4)
UMR: 103663832(IL4)
UAH: 113261716(IL4)
ORO: 101384443(IL4)
ELK: 111141099
FCA: 751514(IL4)
PTG: 102963113(IL4)
PPAD: 109250887(IL4)
AJU: 106970698(IL4)
BTA: 280824(IL4)
BOM: 102272045(IL4)
BIU: 109561213(IL4)
BBUB: 102397131(IL4)
CHX: 100860814(IL4)
OAS: 101122781(IL4)
SSC: 397225(IL4)
CFR: 102515500(IL4)
CDK: 105090136(IL4)
BACU: 103010027(IL4)
LVE: 103069012(IL4)
OOR: 101290331(IL4)
DLE: 111182418(IL4)
PCAD: 102983897(IL4)
ECB: 100034225(IL4)
EPZ: 103563367(IL4)
EAI: 106841015(IL4)
MYB: 102243627(IL4)
MYD: 102773980(IL4)
MNA: 107525027(IL4)
HAI: 109382592(IL4)
DRO: 112318159(IL4)
PALE: 102890025(IL4)
RAY: 107497063(IL4)
MJV: 108390065(IL4)
LAV: 100674484(IL4)
TMU: 101341010
SHR: 100914681(IL4)
PCW: 110211817(IL4)
GGA: 416330(IL4)
NMEL: 110405326(IL4)
TGU: 100231557
FAB: 101822266(IL4)
ETL: 114070738(IL4)
FPG: 101920907(IL4)
FCH: 102059582
EGZ: 104133729(IL4)
NNI: 104012053
ACUN: 113485357(IL4)
PADL: 103915856(IL4)
ASN: 102374890(IL4)
DRE: 100188894(il4)
CMK: 103184173
 » show all
Reference
PMID:2535858
  Authors
Arai N, Nomura D, Villaret D, DeWaal Malefijt R, Seiki M, Yoshida M, Minoshima S, Fukuyama R, Maekawa M, Kudoh J, et al.
  Title
Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.
  Journal
J Immunol 142:274-82 (1989)
  Sequence
[hsa:3565]
LinkDB

KEGG   ORTHOLOGY: K05431
Entry
K05431                      KO                                     

Name
IL7
Definition
interleukin 7
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
Disease
H00842  Epidermodysplasia verruciformis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05431  IL7; interleukin 7
   04151 PI3K-Akt signaling pathway
    K05431  IL7; interleukin 7
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05431  IL7; interleukin 7
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05431  IL7; interleukin 7
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05431  IL7; interleukin 7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05431  IL7; interleukin 7
   00536 Glycosaminoglycan binding proteins
    K05431  IL7; interleukin 7
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K05431  IL7; interleukin 7
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K05431  IL7; interleukin 7
Other DBs
GO: 0005139
Genes
HSA: 3574(IL7)
PTR: 464245(IL7)
PPS: 100986540(IL7)
GGO: 101138372(IL7)
PON: 100447454(IL7)
NLE: 100606680(IL7)
MCC: 574168(IL7)
MCF: 102135001(IL7)
CSAB: 103237005(IL7)
RRO: 104665836(IL7)
RBB: 108526207(IL7)
CJC: 100387798(IL7)
SBQ: 101048813(IL7)
MMU: 16196(Il7)
MCAL: 110290996(Il7)
MPAH: 110321006(Il7)
RNO: 25647(Il7)
MUN: 110556314(Il7)
CGE: 100756443(Il7)
NGI: 103727963(Il7)
HGL: 101713773(Il7)
CCAN: 109698220(Il7)
OCU: 100345409(IL7)
TUP: 102487954(IL7)
CFA: 751768(IL7)
VVP: 112930472(IL7)
AML: 100481194(IL7)
UMR: 103661362(IL7)
UAH: 113253022(IL7)
ORO: 101374293(IL7)
ELK: 111156814
FCA: 101084597(IL7)
PTG: 102960296(IL7)
PPAD: 109269381(IL7)
AJU: 106984935(IL7)
BTA: 280827(IL7)
BOM: 102286767(IL7)
BIU: 109568650(IL7)
BBUB: 102393345(IL7)
CHX: 102182054(IL7)
OAS: 443341(IL7)
SSC: 397253(IL7)
CFR: 102504417(IL7)
CDK: 105088534(IL7)
BACU: 103000105(IL7)
LVE: 103075444(IL7)
OOR: 101276026(IL7)
DLE: 111164935(IL7)
PCAD: 102976783(IL7)
ECB: 100059131(IL7)
EPZ: 103547400(IL7)
EAI: 106839170(IL7)
MYB: 102263096(IL7)
MYD: 102751370(IL7)
MNA: 107539481(IL7)
HAI: 109387835(IL7)
DRO: 112320869(IL7)
PALE: 112472586(IL7)
RAY: 107514111(IL7)
MJV: 108398928(IL7)
LAV: 100658284(IL7)
TMU: 101345060
MDO: 103106447(IL7)
SHR: 116420560(IL7)
PCW: 110199192(IL7)
OAA: 114813216(IL7)
GGA: 420193(IL7)
CJO: 116652977
APLA: 106015872
ACYG: 106030637
TGU: 101234120(IL7)
LSR: 110481797(IL7)
SCAN: 103816360(IL7)
PHI: 102102794(IL7)
PMAJ: 107200924(IL7)
ETL: 114058655(IL7)
FCH: 114017616
EGZ: 104122342
ACUN: 113476147
PADL: 103926225
AAM: 106484576
PSS: 102452006(IL7)
CMY: 102945832(IL7)
CPIC: 101942941(IL7)
ACS: 103278502
LCM: 102353780(IL7)
CMK: 103180773
RTP: 109937090
NVE: 116618886
 » show all
Reference
  Authors
Liao W, Lin JX, Leonard WJ
  Title
IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation.
  Journal
Curr Opin Immunol 23:598-604 (2011)
DOI:10.1016/j.coi.2011.08.003
LinkDB

KEGG   ORTHOLOGY: K05414
Entry
K05414                      KO                                     

Name
IFNA
Definition
interferon alpha
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
ko05320  Autoimmune thyroid disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05414  IFNA; interferon alpha
   04151 PI3K-Akt signaling pathway
    K05414  IFNA; interferon alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05414  IFNA; interferon alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05414  IFNA; interferon alpha
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04621 NOD-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04622 RIG-I-like receptor signaling pathway
    K05414  IFNA; interferon alpha
   04623 Cytosolic DNA-sensing pathway
    K05414  IFNA; interferon alpha
   04650 Natural killer cell mediated cytotoxicity
    K05414  IFNA; interferon alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05414  IFNA; interferon alpha
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K05414  IFNA; interferon alpha
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05414  IFNA; interferon alpha
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05414  IFNA; interferon alpha
   05161 Hepatitis B
    K05414  IFNA; interferon alpha
   05160 Hepatitis C
    K05414  IFNA; interferon alpha
   05171 Coronavirus disease - COVID-19
    K05414  IFNA; interferon alpha
   05164 Influenza A
    K05414  IFNA; interferon alpha
   05162 Measles
    K05414  IFNA; interferon alpha
   05168 Herpes simplex virus 1 infection
    K05414  IFNA; interferon alpha
   05163 Human cytomegalovirus infection
    K05414  IFNA; interferon alpha
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05414  IFNA; interferon alpha
   05169 Epstein-Barr virus infection
    K05414  IFNA; interferon alpha
   05165 Human papillomavirus infection
    K05414  IFNA; interferon alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05414  IFNA; interferon alpha
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interferons
   K05414  IFNA; interferon alpha
Other DBs
GO: 0005132
Genes
HSA: 3439(IFNA1) 3440(IFNA2) 3441(IFNA4) 3442(IFNA5) 3443(IFNA6) 3444(IFNA7) 3445(IFNA8) 3446(IFNA10) 3447(IFNA13) 3448(IFNA14) 3449(IFNA16) 3451(IFNA17) 3452(IFNA21)
PTR: 473185(IFNA21) 473191 473193(IFNA14) 473195(IFNA5) 473196(IFNA6) 473197 473198(IFNA2) 473199(IFNA8) 741660 741747 741797 741978 742651 744748
PPS: 100967539 100968231 100968579 100968923 100969275 100969624 100970300 100970658(IFNA14) 100971675(IFNA6) 100972005 100972354(IFNA2) 100972691(IFNA8) 100973049 100995734(IFNA5)
GGO: 101137870(IFNA21) 101138981 101139336 101139713 101140412 101141176(IFNA6) 101141543 101141916(IFNA2) 101142301(IFNA8) 101142673 115935827 115935828 115935829 115935831 115935832 115935833 115935834
PON: 100432153 100432532(IFNA8) 100432906(IFNA2) 100433301 100434036(IFNA6) 100434796 100435169 100437034 100438149 100438871 100439978(IFNA21) 100443523 100445711 100459543 112134962
NLE: 100594907 100595254(IFNA8) 100595585(IFNA2) 100595932 100596272(IFNA6) 100596946 100597288 100597620 100597957 100598307
MCC: 106992322 106995851(IFNA6) 114672663 114672664 694631 709559(IFNA13) 709755(IFNA8) 709948(IFNA2) 710487 710528 710568 710654(IFNA10) 710751 710848 711088 711252(IFNA21)
MCF: 102115289(IFNA21) 102140303(IFNA1) 102140954(IFNA8) 102141352 102141744(IFNA13) 102142148(IFNA2) 102143043(IFNA6) 102144479(IFNA14) 102144833 102145208 102145962 102146717(IFNA4)
CSAB: 103219366 103219367(IFNA8) 103219368(IFNA2) 103219370 103219372 103219377 103219378 103219379 103219381
RRO: 104670273 104670275(IFNA8) 104670276 104670278(IFNA6) 104670280 104670290 104670292 104680728 115893964 115893973
MMU: 15962(Ifna1) 15964(Ifna11) 15965(Ifna2) 15967(Ifna4) 15968(Ifna5) 15969(Ifna6) 15970(Ifna7) 15972(Ifna9) 15974(Ifnab) 230396(Ifna13) 230398(Ifna16) 242517(Ifna15) 242519(Ifna12) 404549(Ifna14)
RNO: 100912314 298205(Ifna4) 298210(Ifna1) 298211(Ifna11) 298213(Ifna2) 500491(Ifna16l1) 502961(RGD1559679) 690894(Ifna5)
HGL: 101697163
FCA: 101081371 101088440 111557596 493648(IFNA8) 493653(IFNA7) 493840(IFNA5)
PTG: 102956750
BTA: 100329204(IFNAD) 100329206(IFNAG) 100329207(IFNAH) 100329210(INFAF) 100335490 281236(IFNAC) 510726(IFNA16) 515951(IFNAA) 517108 523244 618947 783912 787343
SSC: 100152100(IFN-ALPHA-13) 100152504(IFN-ALPHA-15) 100153325 100153661 100153724(IFN-ALPHA-8) 100154938(IFN-ALPHA-17) 100156561(IFN-ALPHA-10) 100156936 100157352(IFN-ALPHA-1) 100157735(IFN-ALPHA-16) 100157766(IFN-ALPHA-9) 100303758(IFN-ALPHA-5) 100310806(IFN-ALPHAOMEGA) 100737904 397686(IFNA1)
MYB: 106724769
MYD: 102766079
HAI: 109374670
OAA: 100075323(IFN3)
GGA: 100857744(IFNAL4) 100857947(IFNAL5) 100858177 100859032(IFNAL6) 101750245(IFNKL1) 396398(IFNA3) 768614(IFA3L)
MGP: 104915046
CJO: 107306162
NMEL: 110390131
ACYG: 106043723(IFNK) 106044139
LSR: 110470691
SCAN: 103819513 115485133(IFNK)
FAB: 101811547(IFNW1) 101815751
CCW: 104685212
FPG: 101915699(IFNW1)
FCH: 102059593 114016448(IFNK)
CLV: 102092004
ACUN: 113490068 113490202(IFNK)
PMUR: 107293819
TSR: 106542110
PMUA: 114588052(IFNK)
GJA: 107108155
DRE: 100126803(ifnphi3) 360134(ifnphi1)
PRET: 108167267
ALIM: 106535558
SDU: 111220091
BPEC: 110154330
 » show all
Reference
PMID:6157600
  Authors
Mantei N, Schwarzstein M, Streuli M, Panem S, Nagata S, Weissmann C
  Title
The nucleotide sequence of a cloned human leukocyte interferon cDNA.
  Journal
Gene 10:1-10 (1980)
DOI:10.1016/0378-1119(80)90137-7
  Sequence
[hsa:3439]
LinkDB

KEGG   ORTHOLOGY: K05415
Entry
K05415                      KO                                     

Name
IFNB
Definition
interferon beta
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04668  TNF signaling pathway
ko05131  Shigellosis
ko05135  Yersinia infection
ko05142  Chagas disease
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05415  IFNB; interferon beta
   04668 TNF signaling pathway
    K05415  IFNB; interferon beta
   04151 PI3K-Akt signaling pathway
    K05415  IFNB; interferon beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05415  IFNB; interferon beta
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05415  IFNB; interferon beta
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04621 NOD-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04622 RIG-I-like receptor signaling pathway
    K05415  IFNB; interferon beta
   04623 Cytosolic DNA-sensing pathway
    K05415  IFNB; interferon beta
   04650 Natural killer cell mediated cytotoxicity
    K05415  IFNB; interferon beta
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05415  IFNB; interferon beta
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05415  IFNB; interferon beta
   05135 Yersinia infection
    K05415  IFNB; interferon beta
   05152 Tuberculosis
    K05415  IFNB; interferon beta
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05415  IFNB; interferon beta
   05161 Hepatitis B
    K05415  IFNB; interferon beta
   05160 Hepatitis C
    K05415  IFNB; interferon beta
   05171 Coronavirus disease - COVID-19
    K05415  IFNB; interferon beta
   05164 Influenza A
    K05415  IFNB; interferon beta
   05162 Measles
    K05415  IFNB; interferon beta
   05168 Herpes simplex virus 1 infection
    K05415  IFNB; interferon beta
   05163 Human cytomegalovirus infection
    K05415  IFNB; interferon beta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05415  IFNB; interferon beta
   05169 Epstein-Barr virus infection
    K05415  IFNB; interferon beta
   05165 Human papillomavirus infection
    K05415  IFNB; interferon beta
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K05415  IFNB; interferon beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05415  IFNB; interferon beta
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interferons
   K05415  IFNB; interferon beta
Other DBs
GO: 0005132
Genes
HSA: 3456(IFNB1)
PTR: 473183(IFNB1)
PPS: 100995851(IFNB1)
GGO: 101137136(IFNB1)
PON: 100441074(IFNB1)
NLE: 100598986(IFNB1)
MCC: 711414(IFNB1)
MCF: 102115670(IFNB1)
CSAB: 103219383(IFNB1)
RRO: 104670295(IFNB1)
RBB: 108538565(IFNB1)
CJC: 100388391(IFNB1)
SBQ: 101035681(IFNB1)
MMU: 15977(Ifnb1)
MCAL: 110293791(Ifnb1)
MPAH: 110323346(Ifnb1)
RNO: 24481(Ifnb1)
MUN: 110541303(Ifnb1)
CGE: 103160615(Ifnb1)
NGI: 103743951(Ifnb1) 103746144
HGL: 101699042(Ifnb1) 101723869
OCU: 100342931(IFNB1)
TUP: 102493858(IFNB1)
CFA: 481558(IFNB1)
VVP: 112921940(IFNB1)
AML: 100476556(IFNB1)
UMR: 103662150(IFNB1)
UAH: 113260295(IFNB1)
ORO: 101374900(IFNB1)
ELK: 111156577
FCA: 493849(IFNB1)
PTG: 102960421(IFNB1)
PPAD: 109247124(IFNB1)
AJU: 106971145(IFNB1)
SSC: 445459(IFNB1)
CFR: 102513411(IFNB1)
CDK: 105095933(IFNB1)
BACU: 103011926
LVE: 103073772
OOR: 101289058(IFNB1)
DLE: 111174560(IFNB1)
PCAD: 102990155(IFNB1)
MYB: 102261905(IFNB1)
MYD: 102765800(IFNB1)
MNA: 107531433(IFNB1)
HAI: 109396418(IFNB1)
DRO: 112300024(IFNB1)
PALE: 102890512(IFNB1)
RAY: 107518589(IFNB1)
MJV: 108402531(IFNB1)
LAV: 100666438(IFNB1)
TMU: 101349610
MDO: 100021258(IFNB1)
SHR: 100914443
OAA: 100082925(IFNB1)
GGA: 554219(IFNW1)
MGP: 109363864
NMEL: 110390553
ACYG: 106045178
LSR: 110484216
SCAN: 108962800
FPG: 101921672
NNI: 104017595
 » show all
Reference
  Authors
Ohno S, Taniguchi T
  Title
Structure of a chromosomal gene for human interferon beta.
  Journal
Proc Natl Acad Sci U S A 78:5305-9 (1981)
DOI:10.1073/pnas.78.9.5305
  Sequence
[hsa:3456]
LinkDB

KEGG   ORTHOLOGY: K05437
Entry
K05437                      KO                                     

Name
EPO
Definition
erythropoietin
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
Disease
H01360  Allergic rhinitis
H01457  Diabetic retinopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05437  EPO; erythropoietin
   04066 HIF-1 signaling pathway
    K05437  EPO; erythropoietin
   04151 PI3K-Akt signaling pathway
    K05437  EPO; erythropoietin
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05437  EPO; erythropoietin
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05437  EPO; erythropoietin
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05437  EPO; erythropoietin
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05437  EPO; erythropoietin
Cytokines and growth factors [BR:ko04052]
 Cytokines
  CSF and other factors
   K05437  EPO; erythropoietin
Other DBs
GO: 0005128
Genes
HSA: 2056(EPO)
PTR: 463609(EPO)
PPS: 100981507(EPO)
GGO: 101141654(EPO)
PON: 100459890(EPO)
NLE: 100607433(EPO)
MCC: 719294(EPO)
MCF: 101925524(EPO)
CSAB: 103246719(EPO)
RRO: 104673627(EPO)
RBB: 108538126(EPO)
CJC: 100394313(EPO)
SBQ: 101049694(EPO)
MMU: 13856(Epo)
MCAL: 110295387(Epo)
MPAH: 110313227(Epo)
RNO: 24335(Epo)
MUN: 110556771(Epo)
CGE: 100753960(Epo)
NGI: 103733506(Epo)
OCU: 100008786(EPO)
TUP: 102477477(EPO)
CFA: 404002(EPO)
VVP: 112935664(EPO)
AML: 100483785(EPO)
UMR: 103670120(EPO)
UAH: 113267523(EPO)
ORO: 101379507(EPO)
ELK: 111145625
FCA: 493801(EPO)
PTG: 102949527(EPO)
PPAD: 109251316(EPO)
AJU: 106987441(EPO)
BTA: 280784(EPO)
BOM: 102279821(EPO)
BIU: 109578290(EPO)
BBUB: 102397778(EPO)
CHX: 102180175(EPO)
OAS: 443302(EPO)
SSC: 397249(EPO)
CFR: 102508972(EPO)
CDK: 105088586(EPO)
BACU: 102998833(EPO)
LVE: 103071263(EPO)
OOR: 101276756(EPO)
DLE: 111182312(EPO)
PCAD: 102981762(EPO)
ECB: 100033849(EPO)
EPZ: 103555655(EPO)
EAI: 106839355(EPO)
MYB: 102247780(EPO)
MYD: 102762912(EPO)
MNA: 107540896(EPO)
HAI: 109374918(EPO)
DRO: 112315050(EPO)
PALE: 102883166(EPO)
RAY: 107499984(EPO)
MJV: 108409376(EPO)
TMU: 101346088
MDO: 100018159(EPO)
SHR: 100924490(EPO)
PCW: 110202831(EPO)
OAA: 114808091(EPO)
TGU: 115492646(EPO)
PHI: 102100643(EPO)
ASN: 106722510(EPO)
AMJ: 106738663(EPO)
PSS: 102459445(EPO)
CMY: 102937326
PVT: 110082356(EPO)
PBI: 103064242(EPO)
PMUR: 107284999(EPO)
TSR: 106542214(EPO)
PMUA: 114581697(EPO)
XLA: 100505445(epo.S) 108711827(epo.L)
XTR: 100494034(epo)
NPR: 108799511(EPO)
DRE: 100002479(epob) 100004455(epoa)
IPU: 108267596(epo)
PHYP: 113539904(epo)
AMEX: 103031828(epo) 103032190
EEE: 113589005(epo)
TRU: 115250748(epo)
LCO: 104932935(epo)
NCC: 104946298(epo)
MZE: 101486684 112429818(epo)
ONL: 100707671(epo)
OLA: 101161513(epo)
XMA: 102224825(epo)
XCO: 114158019(epo)
PRET: 103480575(epo)
CVG: 107084110(epo)
NFU: 107376930(epo)
KMR: 108229014
ALIM: 106532371(epo)
AOCE: 111571580(epo)
CSEM: 103391052(epo)
POV: 109639698(epo)
LCF: 108902165(epo)
SDU: 111231340(epo)
SLAL: 111646990(epo)
HCQ: 109515099(epo)
BPEC: 110163897(epo)
MALB: 109971919(epo)
SFM: 108929711 108934275(epo)
LCM: 102362147(EPO)
CMK: 103184413(thpo) 103190420 103191442(epo)
RTP: 109910523(epo)
 » show all
Reference
  Authors
Chu CY, Cheng CH, Chen GD, Chen YC, Hung CC, Huang KY, Huang CJ
  Title
The zebrafish erythropoietin: functional identification and biochemical characterization.
  Journal
FEBS Lett 581:4265-71 (2007)
DOI:10.1016/j.febslet.2007.07.073
  Sequence
[dre:100004455]
Reference
  Authors
Chateauvieux S, Grigorakaki C, Morceau F, Dicato M, Diederich M
  Title
Erythropoietin, erythropoiesis and beyond.
  Journal
Biochem Pharmacol 82:1291-303 (2011)
DOI:10.1016/j.bcp.2011.06.045
LinkDB

KEGG   ORTHOLOGY: K05423
Entry
K05423                      KO                                     

Name
CSF3, GCSF
Definition
granulocyte colony-stimulating factor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04657  IL-17 signaling pathway
ko05144  Malaria
ko05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
   04151 PI3K-Akt signaling pathway
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
   04657 IL-17 signaling pathway
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
  09174 Infectious disease: parasitic
   05144 Malaria
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05423  CSF3, GCSF; granulocyte colony-stimulating factor
Cytokines and growth factors [BR:ko04052]
 Cytokines
  CSF and other factors
   K05423  CSF3, GCSF; granulocyte colony-stimulating factor
Genes
HSA: 1440(CSF3)
PTR: 454641(CSF3)
PPS: 100972250(CSF3)
GGO: 101145303(CSF3)
PON: 100442480(CSF3)
NLE: 100582005(CSF3)
MCC: 698961(CSF3)
MCF: 102123087(CSF3)
CSAB: 103243524(CSF3)
RRO: 104655117(CSF3)
RBB: 108527794(CSF3)
SBQ: 101040223(CSF3)
MMU: 12985(Csf3)
MCAL: 110306088(Csf3)
MPAH: 110332564(Csf3)
RNO: 25610(Csf3)
MUN: 110558489(Csf3)
CGE: 100755744(Csf3)
NGI: 103731111(Csf3)
HGL: 101698554(Csf3)
CCAN: 109694433(Csf3)
OCU: 100356652(CSF3)
TUP: 102493161(CSF3)
CFA: 608246(CSF3)
VVP: 112918043(CSF3)
AML: 100481290(CSF3)
UMR: 103661676(CSF3)
UAH: 113265687(CSF3)
ORO: 101385858(CSF3)
ELK: 111151817
FCA: 493700(CSF3)
PTG: 102965612(CSF3)
PPAD: 109247436(CSF3)
AJU: 106980570(CSF3)
BTA: 281096(CSF3)
BOM: 102272188(CSF3)
BIU: 109573417(CSF3)
BBUB: 102406002(CSF3)
CHX: 102185602(CSF3)
OAS: 443523(CSF3)
SSC: 396839(CSF3)
CFR: 102515818(CSF3)
CDK: 105099031(CSF3)
BACU: 103005814(CSF3)
LVE: 103078877(CSF3)
OOR: 101286580(CSF3)
DLE: 111166403(CSF3)
PCAD: 102988264(CSF3)
ECB: 100033922(CSF3)
EPZ: 103550169(CSF3)
EAI: 106826390(CSF3)
MYB: 102248205(CSF3)
MYD: 102760106(CSF3)
MNA: 107528961(CSF3)
HAI: 109380729(CSF3)
DRO: 112316577(CSF3)
PALE: 102882020(CSF3)
RAY: 107520668(CSF3)
MJV: 108385153(CSF3)
LAV: 100657655(CSF3)
TMU: 101359464
MDO: 100016618(CSF3)
SHR: 100925445(CSF3)
PCW: 110215806(CSF3)
OAA: 114815000(CSF3)
GGA: 396216(CSF3)
MGP: 100545706(CSF3)
CJO: 107325065(CSF3)
NMEL: 110388696(CSF3)
TGU: 115490767(CSF3)
LSR: 110471906(CSF3)
SCAN: 103821754(CSF3)
GFR: 102033139(CSF3)
FAB: 101821159(CSF3)
PHI: 102111735(CSF3)
PMAJ: 107215076(CSF3)
CCAE: 111940009(CSF3)
CCW: 104697792(CSF3)
ETL: 114071720(CSF3)
FPG: 101913361(CSF3)
FCH: 102056382(CSF3)
CLV: 102095109(CSF3)
NNI: 104012528(CSF3)
ASN: 102380087(CSF3)
AMJ: 102564831(CSF3)
PSS: 102459061(CSF3)
CMY: 102929617
CPIC: 101952755(CSF3)
ACS: 103279240
PVT: 110085575
PBI: 103067892
PMUR: 114923957
TSR: 106554986
PMUA: 114582801
GJA: 107120752
XLA: 108700769(csf3.L) 108702485(csf3.S)
XTR: 100497396(csf3)
LCO: 104931899(csf3)
MZE: 111500852
XMA: 102218830
XCO: 114151281
PRET: 103481991
NFU: 107390300
KMR: 108237154(csf3)
CSEM: 103393428
POV: 109641811
SLAL: 111656104
HCQ: 109513755
SASA: 106579381
OTW: 112258531
ELS: 105024547
PKI: 111848635(csf3)
 » show all
Reference
PMID:3484805
  Authors
Nagata S, Tsuchiya M, Asano S, Kaziro Y, Yamazaki T, Yamamoto O, Hirata Y, Kubota N, Oheda M, Nomura H, et al.
  Title
Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor.
  Journal
Nature 319:415-8 (1986)
DOI:10.1038/319415a0
  Sequence
[hsa:1440]
Reference
  Authors
Santos MD, Yasuike M, Hirono I, Aoki T
  Title
The granulocyte colony-stimulating factors (CSF3s) of fish and chicken.
  Journal
Immunogenetics 58:422-32 (2006)
DOI:10.1007/s00251-006-0106-5
LinkDB

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