KEGG   ORTHOLOGY: K05701
Entry
K05701                      KO                                     

Name
TJP1, ZO1
Definition
tight junction protein 1
Pathway
ko04520  Adherens junction
ko04530  Tight junction
ko04540  Gap junction
ko05110  Vibrio cholerae infection
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05130  Pathogenic Escherichia coli infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K05701  TJP1, ZO1; tight junction protein 1
   04530 Tight junction
    K05701  TJP1, ZO1; tight junction protein 1
   04540 Gap junction
    K05701  TJP1, ZO1; tight junction protein 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K05701  TJP1, ZO1; tight junction protein 1
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K05701  TJP1, ZO1; tight junction protein 1
   05130 Pathogenic Escherichia coli infection
    K05701  TJP1, ZO1; tight junction protein 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05701  TJP1, ZO1; tight junction protein 1
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     K05701  TJP1, ZO1; tight junction protein 1
Genes
HSA: 7082(TJP1)
PTR: 453253(TJP1)
PPS: 100986510(TJP1)
GGO: 101150313(TJP1)
PON: 100446271(TJP1)
NLE: 100589256(TJP1)
MCC: 720550(TJP1)
MCF: 102140934(TJP1)
CSAB: 103245955(TJP1)
RRO: 104678441(TJP1)
RBB: 108526799(TJP1)
CJC: 100395578(TJP1)
SBQ: 101045649(TJP1)
MMU: 21872(Tjp1)
MCAL: 110297425(Tjp1)
MPAH: 110313355(Tjp1)
RNO: 292994(Tjp1)
MUN: 110546439(Tjp1)
CGE: 100773110(Tjp1)
NGI: 103747201(Tjp1)
HGL: 101696637(Tjp1)
CCAN: 109695793(Tjp1)
OCU: 100346390(TJP1)
TUP: 102502102(TJP1)
CFA: 403752(TJP1)
VVP: 112922382(TJP1)
AML: 100479188(TJP1)
UMR: 103659975(TJP1)
UAH: 113263619(TJP1)
ORO: 101378687(TJP1)
ELK: 111152592
FCA: 101082238(TJP1)
PTG: 102971662(TJP1)
PPAD: 109273325(TJP1)
AJU: 106983747(TJP1)
BTA: 407102(TJP1)
BOM: 102277556(TJP1)
BIU: 109575369(TJP1)
BBUB: 102402627(TJP1)
CHX: 102178667(TJP1)
OAS: 443200(TJP1)
SSC: 100736682(TJP1)
CFR: 102504594(TJP1)
CDK: 105093462(TJP1)
BACU: 103014304
LVE: 103090553
OOR: 101270894(TJP1)
DLE: 111164686(TJP1)
PCAD: 102979621(TJP1)
ECB: 100050412(TJP1)
EPZ: 103559371(TJP1)
EAI: 106834042(TJP1)
MYB: 102240751(TJP1)
MYD: 102766760(TJP1)
MNA: 107527961(TJP1)
HAI: 109380376(TJP1)
DRO: 112306071(TJP1)
PALE: 102891825(TJP1)
RAY: 107515774(TJP1)
MJV: 108390850(TJP1)
LAV: 100654164(TJP1)
TMU: 101350122
MDO: 100021326(TJP1)
SHR: 100924427(TJP1)
PCW: 110192395(TJP1)
OAA: 100078517(TJP1)
GGA: 415388(TJP1)
MGP: 100542752(TJP1)
CJO: 107318600(TJP1)
NMEL: 110403631(TJP1)
APLA: 101791291(TJP1)
ACYG: 106033714(TJP1)
TGU: 100231257(TJP1)
LSR: 110471403(TJP1)
SCAN: 103815972(TJP1)
GFR: 102044956(TJP1)
FAB: 101816839(TJP1)
PHI: 102108685(TJP1)
PMAJ: 107209334(TJP1)
CCAE: 111934185(TJP1)
CCW: 104683818(TJP1)
ETL: 114064909(TJP1)
FPG: 101912031(TJP1)
FCH: 102053227(TJP1)
CLV: 102083865(TJP1)
EGZ: 104130878(TJP1)
NNI: 104016764(TJP1)
ACUN: 113483880(TJP1)
PADL: 103914850(TJP1)
AAM: 106496461(TJP1)
ASN: 102377249(TJP1)
AMJ: 102571498(TJP1)
PSS: 102444512(TJP1)
CMY: 102946392(TJP1)
CPIC: 101931168(TJP1)
ACS: 100562712(tjp1)
PVT: 110074496(TJP1)
PBI: 103065791(TJP1)
PMUR: 107293008(TJP1)
TSR: 106549310(TJP1)
PMUA: 114584155(TJP1)
GJA: 107117388(TJP1)
XLA: 108712948 496307(tjp1.S)
XTR: 100498413(tjp1)
NPR: 108790274(TJP1)
DRE: 378845(tjp1a) 565459(tjp1b)
IPU: 108259232(tjp1) 108274984
PHYP: 113530062(tjp1) 113540846
NCC: 104952246 104960119(tjp1)
CVG: 107087409 107090929(tjp1)
NFU: 107381456 107388620(tjp1)
ALIM: 106526830(tjp1) 106530660
CSEM: 103378762 103380472(tjp1)
ELS: 105015751(tjp1) 106024783
LCM: 102359541(TJP1)
CMK: 103188819(tjp1)
RTP: 109921249(tjp1) 109937982
BFO: 118412273
CIN: 100185856
SPU: 577362
APLC: 110984185
SKO: 100329064
DME: Dmel_CG43140(pyd)
DER: 6552588
DSE: 6607184
DSI: Dsimw501_GD20836(Dsim_GD20836)
DAN: 6500063
DSR: 110191808
DPE: 6591785
DMN: 108154591
DWI: 6647057
DAZ: 108621338
DNV: 108658179
DHE: 111601416
DVI: 6629352
MDE: 101889943
LCQ: 111678055
AAG: 5577336
AME: 725098
BIM: 100748005
BTER: 100649923
CCAL: 108631718
OBB: 114875687
SOC: 105202902
MPHA: 105832524
AEC: 105154166
ACEP: 105622783
PBAR: 105424882
VEM: 105562631
HST: 105187561
DQU: 106741818
CFO: 105255764
LHU: 105679780
PGC: 109860945
OBO: 105277177
PCF: 106789845
NVI: 100123379
CSOL: 105363159
MDL: 103571262
TCA: 655142
DPA: 109545296
ATD: 109608436
NVL: 108558496
BMOR: 101738587
BMAN: 114239378
PMAC: 106721145
PRAP: 110997335
HAW: 110376792
TNL: 113499368
PXY: 105382662
API: 100161207
DNX: 107173222
AGS: 114121897
RMD: 113550703
BTAB: 109035990
CLEC: 106671090
ZNE: 110830123
PVM: 113824346
TUT: 107369585
DPTE: 113799543
BMY: Bm1_09575
TSP: Tsp_11165
PCAN: 112556732
CRG: 105334159
MYI: 110458764
OBI: 106883544
LAK: 106170701
SHX: MS3_03567
NVE: 5513667
EPA: 110237846
ADF: 107339024
AMIL: 114956188
PDAM: 113668338
SPIS: 111338031
DGT: 114525320
 » show all
Reference
  Authors
Huo L, Wen W, Wang R, Kam C, Xia J, Feng W, Zhang M
  Title
Cdc42-dependent formation of the ZO-1/MRCKbeta complex at the leading edge controls cell migration.
  Journal
EMBO J 30:665-78 (2011)
DOI:10.1038/emboj.2010.353
Reference
PMID:8395056
  Authors
Willott E, Balda MS, Fanning AS, Jameson B, Van Itallie C, Anderson JM
  Title
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.
  Journal
Proc Natl Acad Sci U S A 90:7834-8 (1993)
DOI:10.1073/pnas.90.16.7834
  Sequence
[hsa:7082]
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