KEGG   ORTHOLOGY: K05704
Entry
K05704                      KO                                     

Name
SRC
Definition
tyrosine-protein kinase Src [EC:2.7.10.2]
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map04012  ErbB signaling pathway
map04013  MAPK signaling pathway - fly
map04015  Rap1 signaling pathway
map04062  Chemokine signaling pathway
map04137  Mitophagy - animal
map04144  Endocytosis
map04360  Axon guidance
map04370  VEGF signaling pathway
map04510  Focal adhesion
map04520  Adherens junction
map04530  Tight junction
map04540  Gap junction
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04625  C-type lectin receptor signaling pathway
map04727  GABAergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04810  Regulation of actin cytoskeleton
map04912  GnRH signaling pathway
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04921  Oxytocin signaling pathway
map04926  Relaxin signaling pathway
map05100  Bacterial invasion of epithelial cells
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05135  Yersinia infection
map05152  Tuberculosis
map05161  Hepatitis B
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05219  Bladder cancer
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H00978  Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04013 MAPK signaling pathway - fly
    K05704  SRC; tyrosine-protein kinase Src
   04012 ErbB signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04015 Rap1 signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04370 VEGF signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05704  SRC; tyrosine-protein kinase Src
   04137 Mitophagy - animal
    K05704  SRC; tyrosine-protein kinase Src
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K05704  SRC; tyrosine-protein kinase Src
   04520 Adherens junction
    K05704  SRC; tyrosine-protein kinase Src
   04530 Tight junction
    K05704  SRC; tyrosine-protein kinase Src
   04540 Gap junction
    K05704  SRC; tyrosine-protein kinase Src
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05704  SRC; tyrosine-protein kinase Src
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K05704  SRC; tyrosine-protein kinase Src
   04613 Neutrophil extracellular trap formation
    K05704  SRC; tyrosine-protein kinase Src
   04625 C-type lectin receptor signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04062 Chemokine signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
  09152 Endocrine system
   04912 GnRH signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04915 Estrogen signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04917 Prolactin signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04921 Oxytocin signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04926 Relaxin signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
   04919 Thyroid hormone signaling pathway
    K05704  SRC; tyrosine-protein kinase Src
  09156 Nervous system
   04727 GABAergic synapse
    K05704  SRC; tyrosine-protein kinase Src
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K05704  SRC; tyrosine-protein kinase Src
  09158 Development and regeneration
   04360 Axon guidance
    K05704  SRC; tyrosine-protein kinase Src
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K05704  SRC; tyrosine-protein kinase Src
   05207 Chemical carcinogenesis - receptor activation
    K05704  SRC; tyrosine-protein kinase Src
   05208 Chemical carcinogenesis - reactive oxygen species
    K05704  SRC; tyrosine-protein kinase Src
   05203 Viral carcinogenesis
    K05704  SRC; tyrosine-protein kinase Src
  09162 Cancer: specific types
   05219 Bladder cancer
    K05704  SRC; tyrosine-protein kinase Src
  09172 Infectious disease: viral
   05161 Hepatitis B
    K05704  SRC; tyrosine-protein kinase Src
   05168 Herpes simplex virus 1 infection
    K05704  SRC; tyrosine-protein kinase Src
   05163 Human cytomegalovirus infection
    K05704  SRC; tyrosine-protein kinase Src
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05704  SRC; tyrosine-protein kinase Src
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K05704  SRC; tyrosine-protein kinase Src
   05130 Pathogenic Escherichia coli infection
    K05704  SRC; tyrosine-protein kinase Src
   05131 Shigellosis
    K05704  SRC; tyrosine-protein kinase Src
   05135 Yersinia infection
    K05704  SRC; tyrosine-protein kinase Src
   05152 Tuberculosis
    K05704  SRC; tyrosine-protein kinase Src
   05100 Bacterial invasion of epithelial cells
    K05704  SRC; tyrosine-protein kinase Src
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05704  SRC; tyrosine-protein kinase Src
   05418 Fluid shear stress and atherosclerosis
    K05704  SRC; tyrosine-protein kinase Src
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K05704  SRC; tyrosine-protein kinase Src
   01522 Endocrine resistance
    K05704  SRC; tyrosine-protein kinase Src
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05704  SRC; tyrosine-protein kinase Src
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05704  SRC; tyrosine-protein kinase Src
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05704  SRC; tyrosine-protein kinase Src
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  SRC family
   K05704  SRC; tyrosine-protein kinase Src
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    K05704  SRC; tyrosine-protein kinase Src
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    K05704  SRC; tyrosine-protein kinase Src
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K05704  SRC; tyrosine-protein kinase Src
  Macropinocytosis
   Kinases
    K05704  SRC; tyrosine-protein kinase Src
Other DBs
GO: 0004715
Genes
HSA: 6714(SRC)
PTR: 458229(SRC)
PPS: 100986423(SRC)
GGO: 101153251(SRC)
PON: 100436498(SRC)
NLE: 100602214(SRC)
MCC: 701057(SRC)
MCF: 102116225(SRC)
CSAB: 103246384(SRC)
CATY: 105582359(SRC)
PANU: 101025530(SRC)
RRO: 104655840(SRC) 115895854
RBB: 108519844(SRC)
TFN: 117068749(SRC)
PTEH: 111553268(SRC)
CJC: 100386165(SRC)
SBQ: 101051959(SRC)
MMUR: 105866030(SRC)
MMU: 20779(Src)
MCAL: 110310031(Src)
MPAH: 110317793(Src)
RNO: 83805(Src)
MCOC: 116091289(Src)
MUN: 110566227(Src)
CGE: 100757188(Src)
PLEU: 114681835(Src)
NGI: 103752029(Src)
HGL: 101703827(Src)
CCAN: 109702281
OCU: 100341599(SRC)
TUP: 102491807(SRC)
CFA: 485864(SRC)
VVP: 112928171(SRC)
VLG: 121478063(SRC)
AML: 100474271(SRC)
UMR: 103669776(SRC)
UAH: 113258578(SRC)
ORO: 101368668(SRC)
ELK: 111141563
MPUF: 106003305(SRC)
MLX: 118011463(SRC)
FCA: 101100378(SRC)
PTG: 102968822(SRC)
PPAD: 109272472(SRC)
AJU: 106974507(SRC)
HHV: 120228611(SRC)
BTA: 535742(SRC)
BOM: 102284506(SRC)
BIU: 109567428(SRC)
BBUB: 102410133(SRC)
CHX: 102182890(SRC)
OAS: 101103084(SRC)
ODA: 120868632(SRC)
SSC: 100154503(SRC)
CFR: 102520048(SRC)
CDK: 105084996(SRC)
BACU: 103001801(SRC)
LVE: 103072342(SRC)
OOR: 101275089(SRC)
DLE: 111184199(SRC)
PCAD: 102983882(SRC)
ECB: 100069870(SRC)
EPZ: 103560907(SRC)
EAI: 106835088(SRC)
MYB: 102247553(SRC)
MYD: 102769511(SRC)
MMYO: 118662917(SRC)
MNA: 107542143(SRC)
HAI: 109377191(SRC)
DRO: 112303920(SRC)
SHON: 118985454(SRC)
AJM: 119063248(SRC)
MMF: 118618720(SRC)
PALE: 102891249(SRC)
RAY: 107512598(SRC)
MJV: 108401592(SRC)
TOD: 119233001(SRC)
LAV: 100675475(SRC)
TMU: 101342555
MDO: 100029391(SRC)
SHR: 100926529(SRC)
PCW: 110211455(SRC)
OAA: 107547224(SRC)
GGA: 396442(SRC)
PCOC: 116228039
MGP: 100547597(SRC)
CJO: 107322939(SRC)
NMEL: 110408003(SRC)
APLA: 101797249(SRC)
ACYG: 106040941(SRC)
TGU: 100227812(SRC)
LSR: 110469279(SRC)
SCAN: 103818614(SRC)
PMOA: 120511334(SRC)
GFR: 102044186(SRC)
FAB: 101809008(SRC)
PHI: 102105012(SRC)
PMAJ: 107213277(SRC)
CCAE: 111938254(SRC)
CCW: 104687766(SRC)
ETL: 114058090(SRC)
FPG: 101917743(SRC)
FCH: 102052372(SRC)
CLV: 102091546(SRC)
EGZ: 104132176(SRC)
NNI: 104009559(SRC)
ACUN: 113487500(SRC)
PADL: 103912412(SRC)
AAM: 106493368
ASN: 102371874(SRC)
AMJ: 102567804(SRC)
CPOO: 109313187(SRC)
GGN: 109292405(SRC)
PSS: 102462669(SRC)
CMY: 102939716(SRC)
CPIC: 101933235(SRC)
TST: 117885642(SRC)
CABI: 116817358(SRC)
ACS: 100558035(src)
PVT: 110076767(SRC)
PBI: 103068084(SRC)
PMUR: 107287254(SRC)
TSR: 106551377(SRC)
PGUT: 117663550(SRC)
PMUA: 114599561(SRC)
ZVI: 118088466(SRC)
GJA: 107109696(SRC)
XLA: 373647(src.S) 380430(src.L)
XTR: 496893(src)
NPR: 108787987(SRC)
DRE: 325084(src)
IPU: 108255075 108276199(src)
PHYP: 113530503
TRU: 101065281 101078636(src)
NCC: 104942589 104966359(src)
ELY: 117256813 117258173(src)
PLEP: 121946548(src) 121956703
SLUC: 116043666(src) 116051428
ECRA: 117943574 117947225(src)
GAT: 120828725(src) 120835124
MSAM: 119886292 119905139(src)
CUD: 121504662 121517323(src)
OAU: 116319432 116321992(src)
OLA: 101164480 101173856(src)
OML: 112144970 112158705(src)
CVG: 107083711 107097107(src)
CTUL: 119777224(src) 119788640
KMR: 108231632 108237634(src)
ALIM: 106512030 106533680(src)
POV: 109635513(src)
SLAL: 111644184 111660679(src)
XGL: 120803678(src) 120807328
HCQ: 109507451(src) 109513573
LOC: 102697324
LCM: 102360542(SRC)
CMK: 103171906(src)
RTP: 109921818
CIN: 113474091
SCLV: 120336903
SPU: 590498(SFK5)
DME: Dmel_CG7524(Src64B)
DER: 6544189
DSE: 6610805
DSI: Dsimw501_GD13245(Dsim_Src64B)
DAN: 6507355
DSR: 110189978
DPE: 6599673
DMN: 108152166
DWI: 6638649
DAZ: 108613961
DNV: 108651774
DHE: 111599411
DVI: 6636599
MDE: 101901281
LCQ: 111677239
ACOZ: 120947475
AARA: 120894687
AAG: 5565105
AALB: 109399285
CPII: 120429275
AME: 413464
ACER: 108004380
BIM: 100750118
BTER: 100644180
OBB: 114878262
MGEN: 117217416
NMEA: 116426237
CGIG: 122402031
SOC: 105197191
MPHA: 105829413
AEC: 105154274
ACEP: 105619285
PBAR: 105433933
VEM: 105570150
HST: 105191289
DQU: 106744483
CFO: 105252079
FEX: 115240812
LHU: 105679049
PGC: 109856027
OBO: 105284904
PCF: 106785189
NVI: 100120276
CSOL: 105365761
MDL: 103579737
TCA: 656565
DPA: 109541750
AGB: 108909802
NVL: 108560093
APLN: 108732445
PPYR: 116173214
OTU: 111414186
BMOR: 101739984
BMAN: 114243307
MSEX: 115443804
BANY: 112051516
PMAC: 106713731
PPOT: 106104648
PXU: 106121419
PRAP: 111003061
ZCE: 119840742
HAW: 110371981
TNL: 113497265
PXY: 105388402
API: 100160649
DNX: 107167712
AGS: 114131361
RMD: 113558058
BTAB: 109043668
DCI: 103518579
CLEC: 106663205
NLU: 111047541
ZNE: 110831651
CSEC: 111868627
FCD: 110842479
HAME: 121873283
DSV: 119432011
RMP: 119163644
VDE: 111245032
VJA: 111265985
TUT: 107361797
DPTE: 113795885
CEL: CELE_Y92H12A.1(src-1)
CBR: CBG22259(Cbr-src-1)
BMY: BM_BM7182(Bma-src-1)
TSP: Tsp_11907
BGT: 106064370
CRG: 105329816
PMAX: 117324630
LAK: 106155308
EGL: EGR_10536
SPAR: SPRG_09612
 » show all
Reference
PMID:2440106
  Authors
Martinez R, Mathey-Prevot B, Bernards A, Baltimore D
  Title
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart.
  Journal
Science 237:411-5 (1987)
DOI:10.1126/science.2440106
  Sequence
[mmu:20779]
LinkDB

DBGET integrated database retrieval system