KEGG   ORTHOLOGY: K05753
Entry
K05753                      KO                                     

Name
WASF1
Definition
WAS protein family, member 1
Pathway
ko04520  Adherens junction
ko04666  Fc gamma R-mediated phagocytosis
ko04810  Regulation of actin cytoskeleton
ko05100  Bacterial invasion of epithelial cells
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K05753  WASF1; WAS protein family, member 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05753  WASF1; WAS protein family, member 1
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05753  WASF1; WAS protein family, member 1
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K05753  WASF1; WAS protein family, member 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05753  WASF1; WAS protein family, member 1
   05131 Shigellosis
    K05753  WASF1; WAS protein family, member 1
   05100 Bacterial invasion of epithelial cells
    K05753  WASF1; WAS protein family, member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05753  WASF1; WAS protein family, member 1
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    WASP / WAVE
     K05753  WASF1; WAS protein family, member 1
Genes
HSA: 8936(WASF1)
PTR: 462935(WASF1)
PPS: 100967352(WASF1)
GGO: 101131112(WASF1)
PON: 100174148(WASF1)
NLE: 100607631(WASF1)
MCC: 699042(WASF1)
MCF: 102143377(WASF1)
CSAB: 103240591(WASF1)
RRO: 104664499(WASF1)
RBB: 108540547(WASF1)
CJC: 100403045(WASF1)
SBQ: 101046766(WASF1)
MMU: 83767(Wasf1)
MCAL: 110303189(Wasf1)
MPAH: 110326371(Wasf1)
RNO: 294568(Wasf1)
MUN: 110555444(Wasf1)
CGE: 100772707(Wasf1)
NGI: 103749551(Wasf1)
HGL: 101705685(Wasf1)
CCAN: 109685392(Wasf1)
TUP: 102489813(WASF1)
CFA: 475024(WASF1)
VVP: 112925169(WASF1)
AML: 100478002(WASF1)
UMR: 103677004(WASF1)
UAH: 113264744(WASF1)
ORO: 101381480(WASF1)
ELK: 111158284
FCA: 101083083(WASF1)
PTG: 102959553(WASF1)
PPAD: 109263534(WASF1)
AJU: 106968896(WASF1)
BTA: 531488(WASF1)
BOM: 102264451(WASF1)
BIU: 109563830(WASF1)
BBUB: 102393671(WASF1)
CHX: 102175103 102183793(WASF1)
OAS: 101112488(WASF1)
SSC: 100154562(WASF1) 110256054
CFR: 102510461(WASF1)
CDK: 105097105(WASF1)
BACU: 103004278(WASF1)
LVE: 103078061(WASF1)
OOR: 101283798(WASF1)
DLE: 111164540(WASF1)
PCAD: 102980332(WASF1)
ECB: 100066751(WASF1)
EPZ: 103551718(WASF1)
EAI: 106829752(WASF1)
MYB: 102249211(WASF1)
MYD: 102756548(WASF1)
MNA: 107540702(WASF1)
HAI: 109384767(WASF1)
DRO: 112297330(WASF1) 112317940
PALE: 102893633(WASF1)
RAY: 107519372(WASF1)
MJV: 108401289(WASF1)
LAV: 100654554(WASF1)
TMU: 101358300
MDO: 100022094(WASF1)
SHR: 100921263(WASF1)
PCW: 110222862(WASF1)
OAA: 100075943(WASF1)
GGA: 421761(WASF1)
MGP: 100544489(WASF1)
CJO: 107311898(WASF1)
NMEL: 110396515(WASF1)
APLA: 101790467(WASF1)
ACYG: 106032593(WASF1)
TGU: 100189950(WASF1)
LSR: 110483707(WASF1)
SCAN: 103818668(WASF1)
GFR: 102036578(WASF1)
FAB: 101818376(WASF1)
PHI: 102101508(WASF1)
PMAJ: 107201988(WASF1)
CCAE: 111927262(WASF1)
CCW: 104691438(WASF1)
ETL: 114065529(WASF1)
FPG: 101911128(WASF1)
FCH: 102058978(WASF1)
CLV: 102096819(WASF1)
EGZ: 104131560(WASF1)
NNI: 104011156(WASF1)
ACUN: 113478707(WASF1)
PADL: 103918994(WASF1)
AAM: 106489747(WASF1)
ASN: 102368676(WASF1)
AMJ: 102567234(WASF1)
PSS: 102459711(WASF1)
CMY: 102933869(WASF1)
CPIC: 101935787(WASF1)
ACS: 100558519(wasf1)
PVT: 110083153(WASF1)
PBI: 103066762(WASF1)
PMUR: 107297819(WASF1)
TSR: 106545875(WASF1)
PMUA: 114594035(WASF1)
GJA: 107106878(WASF1)
XLA: 108716834(wasf1.L) 444717(wasf1.S)
XTR: 100124768(wasf1)
NPR: 108797683(WASF1)
DRE: 100001221(wasf1)
SRX: 107739187
IPU: 108261263(wasf1)
PHYP: 113528956(wasf1)
AMEX: 103042428(wasf1)
EEE: 113572041(wasf1)
TRU: 101078856(wasf1)
LCO: 104922002(wasf1)
NCC: 104961975(wasf1)
MZE: 101463877(wasf1)
ONL: 100693709(wasf1)
OLA: 101159716(wasf1)
XMA: 102236940(wasf1)
XCO: 114158737(wasf1)
PRET: 103457538(wasf1)
CVG: 107086049(wasf1)
NFU: 107377624(wasf1)
KMR: 108240115(wasf1)
ALIM: 106519773(wasf1)
AOCE: 111580905
CSEM: 103380861(wasf1)
POV: 109636179(wasf1)
LCF: 108895639(wasf1)
SDU: 111239134(wasf1)
SLAL: 111650572(wasf1)
HCQ: 109518133(wasf1)
BPEC: 110153709(wasf1)
MALB: 109953612(wasf1)
SASA: 106571806 106607959(wasf1)
SALP: 111954517(wasf1)
ELS: 105017470(wasf1)
SFM: 108920433(wasf1)
PKI: 111856702(wasf1)
LCM: 102350618
CMK: 103178246(wasf1)
RTP: 109923603(wasf1)
SPU: 584545
EGL: EGR_10005
 » show all
Reference
  Authors
Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK
  Title
Structure and control of the actin regulatory WAVE complex.
  Journal
Nature 468:533-8 (2010)
DOI:10.1038/nature09623
  Sequence
[hsa:8936]
LinkDB

KEGG   ORTHOLOGY: K05748
Entry
K05748                      KO                                     

Name
WASF2
Definition
WAS protein family, member 2
Pathway
ko04520  Adherens junction
ko04666  Fc gamma R-mediated phagocytosis
ko04810  Regulation of actin cytoskeleton
ko05100  Bacterial invasion of epithelial cells
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05135  Yersinia infection
ko05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K05748  WASF2; WAS protein family, member 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05748  WASF2; WAS protein family, member 2
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05748  WASF2; WAS protein family, member 2
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K05748  WASF2; WAS protein family, member 2
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K05748  WASF2; WAS protein family, member 2
   05131 Shigellosis
    K05748  WASF2; WAS protein family, member 2
   05135 Yersinia infection
    K05748  WASF2; WAS protein family, member 2
   05100 Bacterial invasion of epithelial cells
    K05748  WASF2; WAS protein family, member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05748  WASF2; WAS protein family, member 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    WASP / WAVE
     K05748  WASF2; WAS protein family, member 2
Genes
HSA: 10163(WASF2)
PTR: 456675(WASF2) 473870
PPS: 100979214(WASF2) 100994236
GGO: 101139707 101154359(WASF2)
PON: 100437132 100447501(WASF2)
NLE: 100585497(WASF2)
MCC: 716082(WASF2)
MCF: 102120933(WASF2)
CSAB: 103225285(WASF2)
RRO: 104675723(WASF2)
RBB: 108518185(WASF2)
CJC: 100391469(WASF2)
SBQ: 101045414(WASF2)
MMU: 242687(Wasf2)
MCAL: 110292514(Wasf2)
MPAH: 110322998(Wasf2)
RNO: 313024(Wasf2)
MUN: 110552520(Wasf2)
CGE: 100759260(Wasf2)
NGI: 103737074(Wasf2)
HGL: 101701848(Wasf2)
CCAN: 109696055(Wasf2)
OCU: 100355636(WASF2)
TUP: 102501983(WASF2)
CFA: 487343(WASF2)
VVP: 112931646(WASF2)
AML: 100466792(WASF2)
UMR: 103666501(WASF2)
UAH: 113268437(WASF2)
ORO: 101367711(WASF2)
ELK: 111142836
FCA: 101082837(WASF2)
PTG: 102954999(WASF2)
PPAD: 109256761(WASF2)
AJU: 106977544(WASF2)
BTA: 504482(WASF2)
BOM: 102277401(WASF2)
BIU: 109573135(WASF2)
BBUB: 102405935(WASF2)
CHX: 102190345 106503491(WASF2)
OAS: 101107336(WASF2) 101120599
SSC: 100512789(WASF2)
CFR: 102519425(WASF2)
CDK: 105100710(WASF2)
BACU: 103016380(WASF2)
LVE: 103080596(WASF2)
OOR: 101270117(WASF2)
DLE: 111163450(WASF2)
PCAD: 102976265(WASF2)
EPZ: 103550524(WASF2)
EAI: 106839098(WASF2)
MYB: 102257954(WASF2)
MYD: 102752634(WASF2)
MNA: 107540073(WASF2)
HAI: 109386760(WASF2)
DRO: 112299263(WASF2)
PALE: 102886126(WASF2)
RAY: 107503537(WASF2)
MJV: 108406564(WASF2)
LAV: 100675212(WASF2)
TMU: 101340374
MDO: 100618879(WASF2)
SHR: 100927851(WASF2)
PCW: 110206152(WASF2)
OAA: 100681465(WASF2)
GGA: 426359(WASF2)
MGP: 100545294(WASF2)
CJO: 107324004(WASF2)
NMEL: 110387318(WASF2)
APLA: 101793411(WASF2)
ACYG: 106047916(WASF2)
TGU: 100226656(WASF2)
LSR: 110472852(WASF2)
SCAN: 103823598(WASF2)
GFR: 102032350(WASF2)
FAB: 101816860(WASF2)
PHI: 102102838(WASF2)
PMAJ: 107214034(WASF2)
CCAE: 111939071(WASF2)
CCW: 104694624(WASF2)
ETL: 114071330(WASF2)
FPG: 101922545(WASF2)
FCH: 102052077(WASF2)
CLV: 102085911(WASF2)
EGZ: 104134876(WASF2)
NNI: 104017704(WASF2)
ACUN: 113488382(WASF2)
PADL: 103912774(WASF2)
AAM: 106494550(WASF2)
ASN: 102369808(WASF2)
AMJ: 102574052(WASF2)
PSS: 102459291(WASF2)
CMY: 102945284(WASF2)
CPIC: 101940754(WASF2)
ACS: 100551568(wasf2)
PVT: 110088416(WASF2)
PBI: 103055853(WASF2)
PMUR: 107286750(WASF2)
TSR: 106554053(WASF2)
PMUA: 114601496(WASF2)
GJA: 107116649(WASF2)
XLA: 108709524(wasf2.S) 733146(wasf2.L)
XTR: 100125121(wasf2)
NPR: 108786650(WASF2)
DRE: 394056(wasf2)
CCAR: 109112303
IPU: 108257242(wasf2)
PHYP: 113536082(wasf2)
AMEX: 103038132(wasf2)
EEE: 113588356(wasf2)
TRU: 101064106(wasf2)
LCO: 104922104(wasf2)
MZE: 101482993(wasf2)
ONL: 100697143(wasf2)
OLA: 101175491(wasf2)
XMA: 102217914(wasf2)
XCO: 114156204(wasf2)
PRET: 103472306(wasf2)
CVG: 107083297(wasf2)
NFU: 107394778(wasf2)
KMR: 108237969(wasf2)
ALIM: 106515749(wasf2)
AOCE: 111567761(wasf2)
CSEM: 103394337(wasf2)
POV: 109631777(wasf2)
LCF: 108897781(wasf2)
SDU: 111223491(wasf2)
SLAL: 111659362(wasf2)
HCQ: 109509859(wasf2)
BPEC: 110167344(wasf2)
MALB: 109963992(wasf2)
ELS: 105012518(wasf2)
SFM: 108931771(wasf2)
PKI: 111839710(wasf2)
LCM: 102347776(WASF2)
CMK: 103179451(wasf2)
RTP: 109930140
MYI: 110460262
DDI: DDB_G0285253(scrA)
DFA: DFA_08469(scrA)
 » show all
Reference
  Authors
Chereau D, Kerff F, Graceffa P, Grabarek Z, Langsetmo K, Dominguez R
  Title
Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly.
  Journal
Proc Natl Acad Sci U S A 102:16644-9 (2005)
DOI:10.1073/pnas.0507021102
  Sequence
[hsa:10163]
LinkDB

KEGG   ORTHOLOGY: K06083
Entry
K06083                      KO                                     

Name
WASF3
Definition
WAS protein family, member 3
Pathway
ko04520  Adherens junction
ko04666  Fc gamma R-mediated phagocytosis
ko05130  Pathogenic Escherichia coli infection
ko05132  Salmonella infection
ko05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K06083  WASF3; WAS protein family, member 3
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K06083  WASF3; WAS protein family, member 3
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K06083  WASF3; WAS protein family, member 3
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06083  WASF3; WAS protein family, member 3
   05132 Salmonella infection
    K06083  WASF3; WAS protein family, member 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K06083  WASF3; WAS protein family, member 3
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    WASP / WAVE
     K06083  WASF3; WAS protein family, member 3
Genes
HSA: 10810(WASF3)
PTR: 112204139(WASF3) 452502(WASF3)
PPS: 100983777(WASF3)
GGO: 101151762(WASF3)
PON: 100445243(WASF3)
NLE: 100587985(WASF3)
MCC: 709849(WASF3)
MCF: 102131834(WASF3)
CSAB: 103249043(WASF3)
RRO: 104671579(WASF3)
RBB: 108512939(WASF3)
CJC: 100388335(WASF3)
SBQ: 101041139(WASF3)
MMU: 245880(Wasf3)
MCAL: 110294629(Wasf3)
MPAH: 110312868(Wasf3)
RNO: 682937(Wasf3)
CGE: 100759001(Wasf3)
NGI: 103731011(Wasf3)
HGL: 101719051(Wasf3)
CCAN: 109678987(Wasf3)
OCU: 100353601(WASF3)
TUP: 102475767(WASF3)
CFA: 477331(WASF3)
VVP: 112918626(WASF3)
AML: 100467351(WASF3)
UMR: 103664308(WASF3)
UAH: 113251198(WASF3)
ORO: 101384867(WASF3)
ELK: 111159899
FCA: 101086527(WASF3)
PTG: 102958125(WASF3)
PPAD: 109266139(WASF3)
AJU: 106985548(WASF3)
BTA: 540674(WASF3)
BOM: 102277617(WASF3)
BIU: 109566837(WASF3)
BBUB: 102412434(WASF3)
CHX: 102190427(WASF3)
OAS: 101114880(WASF3)
SSC: 100155782(WASF3)
CFR: 102506363(WASF3)
CDK: 105106341(WASF3)
BACU: 103009919(WASF3)
LVE: 103083477(WASF3)
OOR: 101281198(WASF3)
DLE: 111175176(WASF3)
PCAD: 102978208(WASF3)
ECB: 100050895(WASF3)
EPZ: 103561699(WASF3)
EAI: 106832892(WASF3)
MYB: 102242858(WASF3)
MYD: 102753908(WASF3)
MNA: 107546408(WASF3)
HAI: 109387514(WASF3)
DRO: 112296215(WASF3)
PALE: 102893292(WASF3)
RAY: 107498593(WASF3)
MJV: 108394393(WASF3)
LAV: 100658868(WASF3)
TMU: 101345576
MDO: 100015800 100019501(WASF3)
SHR: 100924737(WASF3) 100934823
OAA: 100073372 100089353(WASF3)
GGA: 418934(WASF3) 422323(WASF3L)
MGP: 100545202(WASF3) 100548963
CJO: 107308308(WASF3) 107312862
NMEL: 110389036(WASF3) 110403383
APLA: 101797872 101802693(WASF3)
ACYG: 106038521 106041148(WASF3)
TGU: 100218623(WASF3) 100221700
LSR: 110467882 110476769(WASF3)
SCAN: 103816504 103827326(WASF3)
GFR: 102035199 102038946(WASF3)
FAB: 101809371(WASF3) 101821982
PHI: 102103986 102105898(WASF3)
PMAJ: 107204031 107212765(WASF3)
CCAE: 111923371(WASF3)
CCW: 104689884(WASF3) 104691720
ETL: 114068776 114070454(WASF3)
FPG: 101912273 101924043(WASF3)
FCH: 102050638 102056861(WASF3)
CLV: 102090076 102095877(WASF3)
EGZ: 104126072 104133704(WASF3)
NNI: 104023027(WASF3) 104023505
ACUN: 113479757(WASF3) 113479945
PADL: 103916354 103920100(WASF3)
AAM: 106489842 106500397(WASF3)
ASN: 102368224 102384701(WASF3)
AMJ: 102568457 106737150(WASF3)
PSS: 102449094 102453488(WASF3)
CMY: 102931297 102948125(WASF3)
CPIC: 101940193 101949887(WASF3)
ACS: 100552149(wasf3) 100564556
PVT: 110074267 110076468(WASF3)
PBI: 103060633(WASF3) 103060915
PMUR: 107282924 107288421(WASF3)
TSR: 106538639(WASF3) 106548636
PMUA: 114589133 114595746(WASF3)
GJA: 107112639(WASF3) 107124673
XLA: 108698377 108700078 108708712(wasf3.L) 108709964(wasf3.S)
XTR: 779716(wasf3)
NPR: 108790727(WASF3) 108791906
DRE: 553542(zgc:109889) 555437(si:ch73-362m14.4) 562750(wasf3a) 563632(wasf3b)
NCC: 104948808 104965996(wasf3)
LCM: 102362853 102363912(WASF3)
CMK: 103179519 103183261(wasf3)
CIN: 100181735
SKO: 102804925
BMY: Bm1_54690
NVE: 5504730
EPA: 110231809
ADF: 107342986
AMIL: 114959636
PDAM: 113672015
SPIS: 111334243
HMG: 100207708
 » show all
Reference
  Authors
Sossey-Alaoui K, Li X, Cowell JK
  Title
c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration.
  Journal
J Biol Chem 282:26257-65 (2007)
DOI:10.1074/jbc.M701484200
  Sequence
[hsa:10810]
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