KEGG   ORTHOLOGY: K05829Help
Entry
K05829                      KO                                     

Name
lysY, argC
Definition
LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase [EC:1.2.1.-]
Pathway
ko00220  Arginine biosynthesis
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
   00220 Arginine biosynthesis
    K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.-  
     K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
BRITE hierarchy
Other DBs
RN: R09777 R10931
COG: COG0002
Genes
MSD: MYSTI_01367
CCX: COCOR_02066(argC)
SSX: SACTE_1738
SFA: Sfla_0120
STRP: F750_6904
SFI: SFUL_3351
SCZ: ABE83_19105
SCX: AS200_22010
SRW: TUE45_06897(argC_2)
SPAV: Spa2297_32275
SLAU: SLA_3044
SALJ: SMD11_6707(lysY)
SESP: BN6_56700
PLK: CIK06_18385(argC)
CAI: Caci_6304
RCA: Rcas_3468
CAU: Caur_0335
CAG: Cagg_3596
HAU: Haur_3307
TRO: trd_1518(argC)
STI: Sthe_0216
ATM: ANT_12400(argC)
CAP: CLDAP_41080(argC)
DRA: DR_0963(argC)
DGE: Dgeo_0685
DGO: DGo_CA1602(argC)
DFC: DFI_07605
TRA: Trad_1395
TTH: TT_C1542
TTJ: TTHA1904(argC)
TSC: TSC_c01930(argC1)
TAQ: TO73_0099
TBC: A0O31_00869(argC_1)
MRB: Mrub_2723
MRE: K649_08920(argC)
TTR: Tter_0319
TAI: Taci_0448
TLI: Tlie_1470
MRO: MROS_0164
CABY: Cabys_3149(argC)
PTO: PTO1472
FAI: FAD_0505(lysY)
CDIV: CPM_0548
PHO: PH1720(PH1720)
PAB: PAB0291(argC)
PFU: PF1683
PFI: PFC_10190(argC)
PYN: PNA2_0328
PYS: Py04_1635
TKO: TK0277
THS: TES1_0508
HHB: Hhub_3649(argC)
HJE: HacjB3_00985(argC)
HALH: HTSR_0665(argC)
HHSR: HSR6_0691(argC)
HSU: HLASF_2138(argC)
HSF: HLASA_2172(argC)
HMA: rrnAC2678(argC)
HHI: HAH_3082(argC)
NPH: NP_5260A(argC)
NMO: Nmlp_1242(argC)
HUT: Huta_1501
HTI: HTIA_1540
HMU: Hmuk_0773
HWA: HQ_3715A(argC)
HWC: Hqrw_4130(argC)
HVO: HVO_0045(argC)
HME: HFX_0045(argC)
HLA: Hlac_2615
HTU: Htur_0327
NMG: Nmag_1760(argC)
NAT: NJ7G_0262
SALI: L593_07890(argC)
APE: APE_1462(lysY)
ACJ: ACAM_0921
IHO: Igni_0728
IIS: EYM_02375
IAG: Igag_1754
STO: STK_01950(argC_lysY)
SSO: SSO0155(argC)
SOL: Ssol_1133
SSOA: SULA_1169
SSOL: SULB_1170
SSOF: SULC_1168
SAI: Saci_0750(argC)
SACN: SacN8_03645(argC)
SACR: SacRon12I_03630(argC)
SID: M164_1990
SII: LD85_2245
SIH: SiH_1928
SIR: SiRe_1855
SIC: SiL_1837
MSE: Msed_0164
MCN: Mcup_1909
AHO: Ahos_0883
PAI: PAE2881
PIS: Pisl_0276
PCL: Pcal_0373
PAS: Pars_0966
PYR: P186_1636
POG: Pogu_1380
TNE: Tneu_1837
CMA: Cmaq_1301
TUZ: TUZN_1285
TTN: TTX_0120(lysY_argC)
VDI: Vdis_0193
VMO: VMUT_1533
NMR: Nmar_1289
NIR: NSED_07155(argC)
NKR: NKOR_07275(argC)
NID: NPIRD3C_0835(argC)
NIN: NADRNF5_0667(argC)
NCT: NMSP_0399
NGA: Ngar_c29960(argC)
NVN: NVIE_016490(argC)
NEV: NTE_00734
TAA: NMY3_02222(argC2)
NFN: NFRAN_2984(lysY)
NCV: NCAV_1251(lysY)
NBV: T478_1044(argC)
NDV: NDEV_1624(argC)
KCR: Kcr_0809
BARB: AOA66_0020
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
  Sequence
[tth:TT_C1542]
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0750]
LinkDB All DBs

KEGG   REACTION: R09777Help
Entry
R09777                      Reaction                               

Name
LysW-gamma-L-alpha-aminoadipate 6-semialdehyde:NADP+ 6-oxidoreductase (phosphorylating)
Definition
LysW-gamma-L-alpha-aminoadipyl 6-phosphate + NADPH + H+ <=> LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + NADP+ + Orthophosphate
Equation
Reaction class
RC00001  C00005_C00006
RC00684  C19887_C19888
Enzyme
1.2.1.-
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
Orthology
K05829  LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase [EC:1.2.1.-]
Other DBs
RHEA: 41951
LinkDB All DBs

DBGET integrated database retrieval system