KEGG   ORTHOLOGY: K05830Help
Entry
K05830                      KO                                     

Name
lysJ, argD
Definition
LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase [EC:2.6.1.-]
Pathway
ko00220  Arginine biosynthesis
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01130  Biosynthesis of antibiotics
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05830  lysJ, argD; LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase
   00220 Arginine biosynthesis
    K05830  lysJ, argD; LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K05830  lysJ, argD; LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.-  
     K05830  lysJ, argD; LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class III
   K05830  lysJ, argD; LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase
BRITE hierarchy
Other DBs
RN: R09778 R10932
COG: COG0160 COG4992
Genes
RRS: RoseRS_2722
RCA: Rcas_3460
CAU: Caur_3656
CHL: Chy400_3943
CAG: Cagg_0221
HAU: Haur_3309
TRO: trd_1515
STI: Sthe_0219
ATM: ANT_12380(argD)
PSUB: Pelsub_P1477
CAP: CLDAP_41060(argD)
DRA: DR_0794
DGE: Dgeo_1416
DDR: Deide_16910(argD)
DFC: DFI_08425
TRA: Trad_1401
TTH: TT_C1393
TTJ: TTHA1755
TSC: TSC_c03550(rocD)
TAQ: TO73_0260
TTR: Tter_0321
TAI: Taci_0450
TLI: Tlie_1472
MRO: MROS_0161
CABY: Cabys_1935 Cabys_3152(argD)
PTO: PTO1470
FAI: FAD_0507(lysJ)
CDIV: CPM_0546
PHO: PH1716(PH1716)
PAB: PAB2440(argD)
PFU: PF1685
PYN: PNA2_0326
PYS: Py04_1633
TKO: TK0275
THS: TES1_0510
HHB: Hhub_3651(argD)
HALH: HTSR_0667(argD)
HHSR: HSR6_0693(argD)
HSU: HLASF_2140(argD)
HSF: HLASA_2174(argD)
HMA: rrnAC2675(argD)
HHI: HAH_3080(argD)
NPH: NP_5264A(argD)
NMO: Nmlp_1240(argD)
HUT: Huta_1499
HTI: HTIA_1542
HMU: Hmuk_0775
HWA: HQ_3717A(argD)
HWC: Hqrw_4132(argD)
HVO: HVO_0043(argD)
HME: HFX_0043(argD)
HLA: Hlac_2613
HTU: Htur_0325
NMG: Nmag_1758(argD)
NAT: NJ7G_0260
SALI: L593_07900
APE: APE_1464(lysJ)
ACJ: ACAM_0924(lysJ)
IHO: Igni_0944
IIS: EYM_01870
IAG: Igag_1751
STO: STK_01910(argD_lysJ)
SSO: SSO0160(argD)
SOL: Ssol_1138
SSOA: SULA_1174
SSOL: SULB_1175
SSOF: SULC_1173
SAI: Saci_0755(argD)
SID: M164_1985
SII: LD85_2240
SIH: SiH_1923
SIR: SiRe_1850
SIC: SiL_1832
MSE: Msed_0169
MCN: Mcup_1904
AHO: Ahos_0888
PAI: PAE2515
PIS: Pisl_1923
PCL: Pcal_0283
PAS: Pars_1404
PYR: P186_1106
POG: Pogu_0801
TNE: Tneu_1167
CMA: Cmaq_0767
TUZ: TUZN_0263
TTN: TTX_0623(lysJ_argD)
VDI: Vdis_0197
NMR: Nmar_1291
NID: NPIRD3C_0833(argD)
NIN: NADRNF5_0665(argD)
NCT: NMSP_0397(hemL_1)
NGA: Ngar_c29940(argD2)
NVN: NVIE_016480(argD1)
NEV: NTE_00736
TAA: NMY3_02224(argD)
NFN: NFRAN_2986(argD)
NCV: NCAV_1249(argD)
NBV: T478_1046(argD)
NDV: NDEV_1626(argD)
KCR: Kcr_0813
BARB: AOA66_0022(hemL_1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miyazaki J, Kobashi N, Nishiyama M, Yamane H
  Title
Functional and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate.
  Journal
J Bacteriol 183:5067-73 (2001)
DOI:10.1128/JB.183.17.5067-5073.2001
  Sequence
[tth:TT_C1393]
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0755]
LinkDB All DBs

KEGG   REACTION: R09778Help
Entry
R09778                      Reaction                               

Name
LysW-gamma-L-lysine:2-oxoglutarate 6-aminotransferase
Definition
LysW-gamma-L-alpha-aminoadipate 6-semialdehyde + L-Glutamate <=> LysW-gamma-L-lysine + 2-Oxoglutarate
Equation
Reaction class
RC00006  C00025_C00026
RC00062  C19888_C19889
Enzyme
2.6.1.-
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
Orthology
K05830  LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase [EC:2.6.1.-]
Other DBs
RHEA: 41955
LinkDB All DBs

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