KEGG   ORTHOLOGY: K05831Help
Entry
K05831                      KO                                     

Name
lysK, argE
Definition
[amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
Pathway
ko00220  Arginine biosynthesis
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
   00220 Arginine biosynthesis
    K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.130  [amino group carrier protein]-lysine hydrolase
     K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
    3.5.1.132  [amino group carrier protein]-ornithine hydrolase
     K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
BRITE hierarchy
Other DBs
RN: R09779 R10933
COG: COG0624
Genes
ENF: AKI40_3667
SERA: Ser39006_009310
SERQ: CWC46_09305
MSD: MYSTI_01363
CCX: COCOR_02071(lysK)
SAUC: CA347_95
PMS: KNP414_04935
PMQ: PM3016_4337
PMW: B2K_22470
PIH: UB51_14590
PSWU: SY83_08895
SFA: Sfla_0118
STRP: F750_6906
SPRI: SPRI_3642
SALJ: SMD11_6705
SESP: BN6_56690
ASE: ACPL_7489(lysK)
ACTS: ACWT_7359
CAI: Caci_6288
RCA: Rcas_3459
CAU: Caur_1204
CAG: Cagg_2180
HAU: Haur_3310
TRO: trd_1520
STI: Sthe_0214
ATM: ANT_12370(lysK)
CAP: CLDAP_41050(lysK)
DRA: DR_1413
DGE: Dgeo_1391
DDR: Deide_17960(lysK)
DFC: DFI_03165
TRA: Trad_1404
TTH: TT_C1396
TTJ: TTHA1757
TAQ: TO73_0259
MRB: Mrub_0027
TTR: Tter_0317
TAI: Taci_0451
TLI: Tlie_1473
PTO: PTO1468
FAI: FAD_0509(lysK)
CDIV: CPM_0544
PHO: PH1715(PH1715)
PAB: PAB0294(argE)
PFU: PF1686
PFI: PFC_10175
PYN: PNA2_0325
PYS: Py04_1632
TKO: TK0274
THS: TES1_0511
HHB: Hhub_3652(argE)
HALH: HTSR_0668(argE)
HHSR: HSR6_0694(argE)
HSU: HLASF_2141(argE2)
HSF: HLASA_2175(argE2)
HMA: rrnAC2674(gltCP)
HHI: HAH_3079(argE1)
NPH: NP_5266A(argE)
NMO: Nmlp_1239(argE)
HUT: Huta_1498
HTI: HTIA_1543
HMU: Hmuk_0776
HWA: HQ_3718A(argE2)
HWC: Hqrw_4133(argE2)
HVO: HVO_0042(argE)
HME: HFX_0042(argE)
HLA: Hlac_2612
HTU: Htur_0324
NMG: Nmag_1757(argE)
NAT: NJ7G_0259
SALI: L593_07905
APE: APE_1467.1(lysK)
ACJ: ACAM_0925(lysK)
IHO: Igni_0664
IIS: EYM_06525
IAG: Igag_1750
STO: STK_01900(lysK)
SSO: SSO0162
SOL: Ssol_1139
SSOA: SULA_1175
SSOL: SULB_1176
SSOF: SULC_1174
SAI: Saci_0756
SID: M164_1984
SII: LD85_2239
SIH: SiH_1922
SIR: SiRe_1849
SIC: SiL_1831
MSE: Msed_0170
MCN: Mcup_1903
AHO: Ahos_0889
PAI: PAE2798
PIS: Pisl_1394
PCL: Pcal_1259
PAS: Pars_0867
PYR: P186_1739
POG: Pogu_1471
TNE: Tneu_1861
CMA: Cmaq_1676
TUZ: TUZN_1280
TTN: TTX_0118(lysK_argE)
VDI: Vdis_0199
VMO: VMUT_1537
NMR: Nmar_1296
NCT: NMSP_0392
NGA: Ngar_c14550(lysK)
NVN: NVIE_002650(lysK)
NEV: NTE_01581
TAA: NMY3_02229(dapE_2)
NFN: NFRAN_2991(dapE)
NCV: NCAV_1408
NBV: T478_1051
NDV: NDEV_1631
KCR: Kcr_0814
BARB: AOA66_0023
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miyazaki J, Kobashi N, Fujii T, Nishiyama M, Yamane H
  Title
Characterization of a lysK gene as an argE homolog in Thermus thermophilus HB27.
  Journal
FEBS Lett 512:269-74 (2002)
DOI:10.1016/S0014-5793(02)02290-1
  Sequence
[tth:TT_C1396]
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0756]
LinkDB All DBs

KEGG   REACTION: R09779Help
Entry
R09779                      Reaction                               

Name
LysW-gamma-L-lysine carboxypeptidase
Definition
LysW-gamma-L-lysine + H2O <=> L-Lysine + alpha-Aminoadipate carrier protein LysW
Equation
Comment
acetyl-lysine deacetylase, lysK
Reaction class
RC00064  C00047_C19889
RC00090  C19885_C19889
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
Orthology
K05831  [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
Other DBs
RHEA: 48687
LinkDB All DBs

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