KEGG   ORTHOLOGY: K05863
Entry
K05863                      KO                                     

Name
SLC25A4S, ANT
Definition
solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04217  Necroptosis
ko04218  Cellular senescence
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
ko05017  Spinocerebellar ataxia
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05164  Influenza A
ko05166  Human T-cell leukemia virus 1 infection
Disease
H00469  Mitochondrial DNA depletion syndrome
H01118  Progressive external ophthalmoplegia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   04022 cGMP-PKG signaling pathway
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   04218 Cellular senescence
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05012 Parkinson disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05016 Huntington disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05017 Spinocerebellar ataxia
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05020 Prion disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05022 Pathways of neurodegeneration - multiple diseases
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05164 Influenza A
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Other mitochondrial DNA transcription and translation factors
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC25: Mitochondrial carrier
   K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Other DBs
GO: 0015207
TC: 2.A.29.1
Genes
HSA: 291(SLC25A4) 292(SLC25A5) 293(SLC25A6) 83447(SLC25A31)
PTR: 101057286 107972834 112206875(SLC25A6) 461632(SLC25A4) 736938(SLC25A5) 742937(SLC25A31)
PPS: 100971042(SLC25A4) 100981051 100984012(SLC25A31) 100991246(SLC25A5)
GGO: 101132025(SLC25A4) 101138376(SLC25A5) 101143704(SLC25A31)
PON: 100173820(SLC25A5) 100432368(SLC25A31) 100437258(SLC25A4) 100445977(SLC25A6) 100445983
NLE: 100582353(SLC25A5) 100599131(SLC25A31) 100601532(SLC25A4)
MCC: 693502(SLC25A5) 695102(SLC25A4) 710042(SLC25A31) 719811
MCF: 102120762(SLC25A4) 102129825(SLC25A6) 102138876(SLC25A5) 102143674(SLC25A31)
CSAB: 103220507 103236238(SLC25A31) 103236621(SLC25A4) 103247334(SLC25A5) 103247519(SLC25A6)
RRO: 104661254 104663348(SLC25A6) 104673801(SLC25A4) 104673881(SLC25A5) 115899258
CJC: 100387000(SLC25A5) 100397220(SLC25A31) 100403424(SLC25A6) 100405844(SLC25A6) 100411371(SLC25A4) 100415405 108588056
MMU: 11739(Slc25a4) 11740(Slc25a5) 73333(Slc25a31)
MCAL: 110286753(Slc25a5) 110291352(Slc25a31) 110300115(Slc25a4)
MPAH: 110313362(Slc25a5) 110320569(Slc25a31) 110336417(Slc25a4)
RNO: 100909799 25176(Slc25a5) 689108(Slc25a31) 85333(Slc25a4)
MUN: 110556812(Slc25a4) 110566446(Slc25a5) 110566972(Slc25a31)
CGE: 100751779(Slc25a4) 100761654 100769087(Slc25a5) 100773145(Slc25a31)
NGI: 103726219(Slc25a31) 103742868(Slc25a5) 103750115(Slc25a6) 103750480(Slc25a4)
HGL: 101697130(Slc25a5) 101698774(Slc25a31) 101703823(Slc25a6) 101706144(Slc25a4)
CCAN: 109675843 109681419(Slc25a31) 109684937(Slc25a4) 109688777(Slc25a6)
OCU: 100009414(SLC25A4) 100337764(SLC25A5) 100346477(SLC25A31) 100349768 100356326
TUP: 102469729 102470597(SLC25A5) 102475617(SLC25A6) 102480098 102488121(SLC25A31) 102493892(SLC25A4)
CFA: 475630(SLC25A4) 480830(SLC25A6) 483832(SLC25A31) 492093(SLC25A5)
VVP: 112908953(SLC25A6) 112910590(SLC25A5) 112931611(SLC25A31) 112934741(SLC25A4)
AML: 100464085(SLC25A31) 100469507(SLC25A6) 100473508(SLC25A4) 100476732(SLC25A5)
UMR: 103656991(SLC25A31) 103666331(SLC25A6) 103677737(SLC25A5) 103681007(SLC25A4)
UAH: 113240791(SLC25A6) 113241271(SLC25A5) 113255470(SLC25A31) 113262270(SLC25A4)
ORO: 101366629(SLC25A31) 101367537 101371414 101372733(SLC25A4) 101374224 101384049(SLC25A6)
FCA: 101082635(SLC25A5) 101086294(SLC25A31) 101096309(SLC25A4) 101100868(SLC25A6) 111558717
PTG: 102960718(SLC25A4) 102962163 102966182(SLC25A6) 102971432(SLC25A31) 102972215(SLC25A5)
PPAD: 109249044(SLC25A31) 109250770(SLC25A5) 109251009(SLC25A4) 109256146(SLC25A6)
AJU: 106970899(SLC25A5) 106982044(SLC25A6) 106982226(SLC25A4) 106988175(SLC25A31)
BTA: 282478(SLC25A4) 282479(SLC25A5) 282480(SLC25A6) 541168(SLC25A31) 787122
BOM: 102275932(SLC25A5) 102280125(SLC25A6) 102286445(SLC25A4) 102287077(SLC25A31)
BIU: 109553455(SLC25A4) 109561148 109571027(SLC25A31)
BBUB: 102400898(SLC25A6) 102405012(SLC25A31) 102413768(SLC25A4) 102415498(SLC25A5)
CHX: 100861351(SLC25A4) 102173075(SLC25A5) 102176546(SLC25A31) 102178813(SLC25A6)
OAS: 100147787(SLC25A4) 100147789(SLC25A6) 101122465(SLC25A31)
SSC: 100158185(SLC25A5) 100517196(SLC25A4) 100518564(SLC25A31) 403155(SLC25A6)
CFR: 102503644(SLC25A31) 102512378(SLC25A6) 102513318(SLC25A4) 102516285(SLC25A5) 102520419
CDK: 105084439(SLC25A4) 105087057(SLC25A31) 105093951(SLC25A5) 105103090(SLC25A6)
BACU: 102999263(SLC25A4) 103009487(SLC25A6) 103012312(SLC25A5) 103012461(SLC25A31)
LVE: 103068650(SLC25A31) 103075399(SLC25A4) 103083138(SLC25A6) 103091053(SLC25A5)
OOR: 101275776(SLC25A5) 101278211(SLC25A31) 101279540(SLC25A6) 101288695(SLC25A4)
DLE: 111165889(SLC25A31) 111168263(SLC25A6) 111169059(SLC25A5) 111173410(SLC25A4)
PCAD: 102975203(SLC25A5) 102978018(SLC25A31) 102985148(SLC25A6) 102990817(SLC25A4) 102996437
ECB: 100050762(SLC25A4) 100059103(SLC25A5) 100071908(SLC25A31) 100146128(SLC25A6)
EPZ: 103540840 103545106 103549138(SLC25A4) 103562821(SLC25A31)
EAI: 106829894(SLC25A31) 106830087(SLC25A4) 106841502(SLC25A5) 106842512(SLC25A6)
MYB: 102239133(SLC25A31) 102246203 102255058(SLC25A4) 102256266 102256951(SLC25A5)
MNA: 107529320(SLC25A5) 107529763(SLC25A31) 107535760(SLC25A4) 107542290 107543961
HAI: 109374086 109375563(SLC25A6) 109390884 109394950(SLC25A31) 109395862(SLC25A4)
DRO: 112301943 112306713(SLC25A4) 112310580(SLC25A5) 112312642(SLC25A31) 112313387(SLC25A6)
PALE: 102878001(SLC25A4) 102885895 102896364(SLC25A6) 102896575(SLC25A5) 102897294(SLC25A31)
RAY: 107498648 107506524(SLC25A5) 107510449(SLC25A4) 107512501(SLC25A31) 107512547(SLC25A6)
MJV: 108386810(SLC25A5) 108389683(SLC25A6) 108396047(SLC25A31) 108410160(SLC25A4)
LAV: 100655324(SLC25A6) 100662489(SLC25A4) 100664844(SLC25A5) 100669563(SLC25A31)
SHR: 100920060(SLC25A4) 100929945(SLC25A31) 116422319(SLC25A6)
PCW: 110209837(SLC25A31) 110212779(SLC25A6) 110220099 110222593(SLC25A4)
OAA: 100080434(SLC25A5) 100087351(SLC25A4) 114812883(SLC25A31)
GGA: 374072(SLC25A6) 422546(SLC25A4) 772225(SLC25A5)
MGP: 100545489(SLC25A5) 100547105(SLC25A4) 100547970(SLC25A6)
CJO: 107305856(SLC25A6) 107312944(SLC25A5) 107313279(SLC25A4)
NMEL: 110398592(SLC25A4) 110403250(SLC25A5) 110405908(SLC25A6)
APLA: 101791414(SLC25A5) 101794225(SLC25A4) 101799034(SLC25A6)
ACYG: 106035124(SLC25A4) 106035685(SLC25A6) 106037651(SLC25A5) 106042436(SLC25A31)
TGU: 100190145(SLC25A5) 100190146(SLC25A6) 100227980(SLC25A4)
LSR: 110476947(SLC25A4) 110479392(SLC25A6) 110480478(SLC25A5)
SCAN: 103812627(SLC25A6) 103816532(SLC25A5) 103825605(SLC25A4)
GFR: 102031695(SLC25A4) 102038498(SLC25A6) 102039001(SLC25A5)
FAB: 101810172(SLC25A4) 101815466(SLC25A5) 101818491(SLC25A6)
PHI: 102105225(SLC25A4) 102110337(SLC25A5) 102112843(SLC25A6)
PMAJ: 107201509(SLC25A6) 107203619(SLC25A4) 107203940(SLC25A5)
CCAE: 111928433(SLC25A4) 111944386 111944525(SLC25A6)
CCW: 104686297(SLC25A6) 104690855(SLC25A4) 104694471(SLC25A5)
ETL: 114055574(SLC25A4) 114065037(SLC25A5) 114066994(SLC25A6)
FPG: 101911995(SLC25A5) 101917366(SLC25A6) 101917374(SLC25A4) 101923649(SLC25A31)
FCH: 102052754(SLC25A5) 102056660(SLC25A4) 102057129(SLC25A6) 102058611(SLC25A31)
CLV: 102090099(SLC25A5) 102094223(SLC25A6) 102096475(SLC25A4)
EGZ: 104124066(SLC25A5) 104125138(SLC25A6) 104129313(SLC25A31) 104129432(SLC25A4)
NNI: 104009846(SLC25A6) 104015971(SLC25A31) 104019084(SLC25A5) 104021290(SLC25A4)
ACUN: 113478665(SLC25A6) 113479234(SLC25A4) 113480143(SLC25A5)
PADL: 103922565(SLC25A4) 103923034(SLC25A5) 103923051(SLC25A6) 103926144(SLC25A31)
AAM: 106483997 106487533(SLC25A5) 106490690(SLC25A6) 106491850(SLC25A31)
ASN: 102371094(SLC25A4) 102376128(SLC25A5) 102384953 102387986(SLC25A31)
AMJ: 102562521(SLC25A6) 102565969(SLC25A31) 102576169(SLC25A4) 106736959(SLC25A5)
PSS: 102444939(SLC25A31) 102446093(SLC25A5) 102458327(SLC25A6) 102461807(SLC25A4)
CMY: 102930600(SLC25A4) 102940968(SLC25A6) 102941037(SLC25A5) 102943274(SLC25A31)
CPIC: 101935127(SLC25A31) 101937873(SLC25A6) 101947225(SLC25A5) 101952179(SLC25A4)
ACS: 100554158(slc25a6) 100557696(slc25a31) 100558779(slc25a5) 100563345(slc25a4)
PVT: 110072866(SLC25A31) 110083822(SLC25A4) 110089751 110090254(SLC25A5)
PMUR: 107289684 107290576(SLC25A31) 107301632 107302668(SLC25A4)
TSR: 106540012(SLC25A4) 106546231(SLC25A31) 106547817 106552730
PMUA: 114589016(SLC25A5) 114596329(SLC25A6) 114604061(SLC25A31) 114604671(SLC25A4)
GJA: 107108997(SLC25A31) 107116719(SLC25A4) 107120378(SLC25A6) 107123722(SLC25A5)
XLA: 100126647(slc25a31.L) 108700136 108705979 380187(slc25a5.L) 432212(slc25a4.L)
XTR: 394504(slc25a4) 394508(slc25a5)
NPR: 108790928(SLC25A4) 108798305(SLC25A5)
DRE: 100038774(si:dkey-251i10.1) 192321(slc25a5) 327067(slc25a4) 566370(slc25a6)
IPU: 100528279(adt3) 100528860(slc25a5) 108260169 108260845(slc25a4) 108266970(SLC25A5) 108273102(SLC25A4)
TRU: 743354(ants6) 751094(slc25a5) 751095(slc25a4)
PRET: 103466173(slc25a4) 103471639 103471640(slc25a5) 103475848
AOCE: 111575325(slc25a4) 111578216 111587178
BPEC: 110158394 110158852 110165268(slc25a4)
SASA: 100194655 106563614(ADT2) 106602726(slc25a4) 106603043 106604721(ADT2) 106611749(ADT2)
ELS: 105010883 105021093(slc25a4) 105029427(adt2) 105031340
LCM: 102347011(SLC25A5) 102349731 102350158(SLC25A31) 102356552(SLC25A4)
CMK: 103178208(slc25a4) 103178409(slc25a5) 103190058(slc25a31)
RTP: 109914009 109924065 109928789(slc25a31)
DME: Dmel_CG1683(Ant2) Dmel_CG16944(sesB)
DSI: Dsimw501_GD16013(Dsim_GD16013) Dsimw501_GD16014(Dsim_GD16014)
DYA: Dyak_GE15371(Dyak_sesB) Dyak_GE15372
DPO: Dpse_GA14170 Dpse_GA14229(Dpse_sesB)
MDE: 101889408
AGA: AgaP_AGAP002358(ADT2_ANOGA) AgaP_AGAP006782(ADT1_ANOGA)
AME: 107964398 406075(Ant)
HST: 105185646
LHU: 105675415
NVI: 100117058
MDL: 103577361
BMOR: 101738591(BmANTI2) 101742523(BmANTI1) 692626(Ant)
BTAB: 109037679
ZNE: 110836319
DPTE: 113792844
CEL: CELE_C47E12.2(C47E12.2) CELE_F25B4.7(F25B4.7) CELE_K01H12.2(ant-1.3) CELE_R07E3.4(R07E3.4) CELE_T01B11.4(ant-1.4) CELE_T27E9.1(ant-1.1) CELE_W02D3.6(ant-1.2)
CBR: CBG03436 CBG03723(Cbr-tag-316) CBG09342 CBG17210 CBG20451 CBG21201(Cbr-tag-61)
TSP: Tsp_01983
MYI: 110465105
OBI: 106870577
SHX: MS3_03206
EGL: EGR_03392
DGT: 114520366
HMG: 105843221
ATH: AT3G08580(AAC1) AT4G28390(AAC3) AT5G13490(AAC2) AT5G17400(ER-ANT1) AT5G56450(PM-ANT)
LJA: Lj0g3v0065999.1(Lj0g3v0065999.1) Lj0g3v0073249.1(Lj0g3v0073249.1) Lj0g3v0251339.1(Lj0g3v0251339.1) Lj0g3v0251339.2(Lj0g3v0251339.2) Lj0g3v0251339.3(Lj0g3v0251339.3) Lj0g3v0350069.1(Lj0g3v0350069.1) Lj1g3v1786120.1(Lj1g3v1786120.1) Lj2g3v0661560.1(Lj2g3v0661560.1) Lj3g3v0840550.1(Lj3g3v0840550.1) Lj3g3v2809810.1(Lj3g3v2809810.1) Lj4g3v3114850.1(Lj4g3v3114850.1)
DOSA: Os02t0718900-01(Os02g0718900) Os05t0302700-01(Os05g0302700) Os05t0539600-01(Os05g0539600) Os11t0661300-01(Os11g0661300)
ATS: 109744107(LOC109744107) 109745669(LOC109745669) 109770094(LOC109770094) 109776847(LOC109776847) 109778805(LOC109778805)
ZMA: 100274442 100282898 100284305(gpm280a) 103630666 542386(ANT1) 542389(ANT2)
SCE: YBL030C(PET9) YBR085W(AAC3) YMR056C(AAC1)
ERC: Ecym_7441
KMX: KLMA_70354(AAC)
NCS: NCAS_0A08210(NCAS0A08210) NCAS_0A10880(NCAS0A10880) NCAS_0I01330(NCAS0I01330)
NDI: NDAI_0A05420(NDAI0A05420) NDAI_0A07670(NDAI0A07670) NDAI_0G04660(NDAI0G04660)
TPF: TPHA_0M01360(TPHA0M01360) TPHA_0N01580(TPHA0N01580)
TBL: TBLA_0G03560(TBLA0G03560)
TDL: TDEL_0B07140(TDEL0B07140) TDEL_0F02010(TDEL0F02010)
KAF: KAFR_0B05170(KAFR0B05170) KAFR_0C00210(KAFR0C00210)
PIC: PICST_45104(PET9) PICST_85436(ADT1)
CAL: CAALFM_C500590WA(PET9)
SLB: AWJ20_4572(PET9)
NCR: NCU09477(aac)
NTE: NEUTE1DRAFT130134(NEUTE1DRAFT_130134)
MGR: MGG_16149
SSCK: SPSK_01245
MAW: MAC_03644
MAJ: MAA_02544
CMT: CCM_00240
MBE: MBM_07006
ANI: AN4064.2
ANG: ANI_1_558164(An18g04220)
ABE: ARB_05611
TVE: TRV_07210
PTE: PTT_16860
SPO: SPBC530.10c(anc1)
TASA: A1Q1_01637
ABP: AGABI1DRAFT110533(AGABI1DRAFT_110533)
ABV: AGABI2DRAFT189567(AGABI2DRAFT_189567)
MGL: MGL_3651
MRT: MRET_2596
DDI: DDB_G0267454(ancA)
PCB: PCHAS_052040(PC000019.01.0)
TPV: TP02_0141
BBO: BBOV_III010060(17.m07874)
CPV: cgd8_1210
SMIN: v1.2.036479.t1(symbB.v1.2.036479.t1) v1.2.042182.t1(symbB.v1.2.042182.t1)
TPS: THAPSDRAFT_39143(ANT1)
LMA: LMJF_19_0200(ANC1) LMJF_19_0210(ANC2)
LIF: LINJ_19_0190(ANC1) LINJ_19_0200(ANC2)
LPAN: LPMP_190170(ANC1) LPMP_190180(ANC2)
 » show all
Reference
PMID:2823266
  Authors
Neckelmann N, Li K, Wade RP, Shuster R, Wallace DC
  Title
cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.
  Journal
Proc Natl Acad Sci U S A 84:7580-4 (1987)
DOI:10.1073/pnas.84.21.7580
  Sequence
[hsa:291]
Reference
  Authors
Kim YH, Haidl G, Schaefer M, Egner U, Mandal A, Herr JC
  Title
Compartmentalization of a unique ADP/ATP carrier protein SFEC (Sperm Flagellar Energy Carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece.
  Journal
Dev Biol 302:463-76 (2007)
DOI:10.1016/j.ydbio.2006.10.004
  Sequence
[hsa:83447] [mmu:73333]
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