KEGG   ORTHOLOGY: K05871
Entry
K05871                      KO                                     

Name
PTK2B, FAK2
Definition
focal adhesion kinase 2 [EC:2.7.10.2]
Pathway
map04020  Calcium signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04670  Leukocyte transendothelial migration
map04912  GnRH signaling pathway
map05135  Yersinia infection
map05161  Hepatitis B
map05163  Human cytomegalovirus infection
map05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   04072 Phospholipase D signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   04670 Leukocyte transendothelial migration
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   04062 Chemokine signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
  09152 Endocrine system
   04912 GnRH signaling pathway
    K05871  PTK2B, FAK2; focal adhesion kinase 2
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   05161 Hepatitis B
    K05871  PTK2B, FAK2; focal adhesion kinase 2
   05163 Human cytomegalovirus infection
    K05871  PTK2B, FAK2; focal adhesion kinase 2
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05871  PTK2B, FAK2; focal adhesion kinase 2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05871  PTK2B, FAK2; focal adhesion kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K05871  PTK2B, FAK2; focal adhesion kinase 2
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  FAK family
   K05871  PTK2B, FAK2; focal adhesion kinase 2
Other DBs
GO: 0004715
Genes
HSA: 2185(PTK2B)
PTR: 464073(PTK2B)
PPS: 100991936(PTK2B)
GGO: 101135800(PTK2B)
PON: 100174613(PTK2B)
NLE: 100599503(PTK2B)
MCC: 712787(PTK2B)
MCF: 102130539(PTK2B)
CSAB: 103215524(PTK2B)
CATY: 105579176(PTK2B)
PANU: 101023887(PTK2B)
RRO: 104673947(PTK2B)
RBB: 108537591(PTK2B)
TFN: 117093809(PTK2B)
PTEH: 111545732(PTK2B)
CJC: 100404210(PTK2B)
SBQ: 101032561(PTK2B)
MMUR: 105877126(PTK2B)
MMU: 19229(Ptk2b)
MCAL: 110308944(Ptk2b)
MPAH: 110325924(Ptk2b)
RNO: 50646(Ptk2b)
MCOC: 116085323(Ptk2b)
MUN: 110559230(Ptk2b)
CGE: 100758086(Ptk2b)
PLEU: 114707316(Ptk2b)
NGI: 103730003(Ptk2b)
HGL: 101714384(Ptk2b)
CCAN: 109698054(Ptk2b)
OCU: 100342358(PTK2B)
TUP: 102481841(PTK2B)
CFA: 486102(PTK2B)
VVP: 112926788(PTK2B)
VLG: 121497328(PTK2B)
AML: 100478801(PTK2B)
UMR: 103675966(PTK2B)
UAH: 113269957(PTK2B)
ORO: 101373391(PTK2B)
ELK: 111153692
MPUF: 101688546(PTK2B)
EJU: 114217420(PTK2B)
MLX: 118022110(PTK2B)
FCA: 101091691(PTK2B)
PTG: 102955963(PTK2B)
PPAD: 109262338(PTK2B)
AJU: 106973108(PTK2B)
HHV: 120220289(PTK2B)
BTA: 541008(PTK2B)
BOM: 102266592(PTK2B)
BIU: 109563157(PTK2B)
BBUB: 102411722(PTK2B)
CHX: 102184810(PTK2B)
OAS: 101106906(PTK2B)
SSC: 100157507(PTK2B)
CFR: 102520664(PTK2B)
CDK: 105102240(PTK2B)
BACU: 103016023(PTK2B)
LVE: 103083166(PTK2B)
OOR: 101281402(PTK2B)
DLE: 111185408(PTK2B)
PCAD: 102995810(PTK2B)
ECB: 100054547(PTK2B)
EPZ: 103550428(PTK2B)
EAI: 106832511(PTK2B)
MYB: 102256791(PTK2B)
MYD: 102756394(PTK2B)
MMYO: 118659060(PTK2B)
MNA: 107538557(PTK2B)
HAI: 109379535(PTK2B)
DRO: 112312413(PTK2B)
SHON: 118984359(PTK2B)
AJM: 119044625(PTK2B)
MMF: 118615360(PTK2B)
PALE: 102886432(PTK2B)
RAY: 107515459(PTK2B)
MJV: 108394326(PTK2B)
TOD: 119258011(PTK2B)
LAV: 100667505(PTK2B)
TMU: 101354947
MDO: 100025175(PTK2B)
SHR: 100923387(PTK2B)
PCW: 110206529(PTK2B)
OAA: 100085161(PTK2B)
GGA: 421998(PTK2B)
PCOC: 116235641(PTK2B)
MGP: 100549921(PTK2B)
CJO: 107312386(PTK2B)
NMEL: 110395785(PTK2B)
APLA: 101792285(PTK2B)
ACYG: 106049520(PTK2B)
LSR: 110477410(PTK2B)
PMOA: 120503435(PTK2B)
FAB: 101806020(PTK2B)
PHI: 102099730(PTK2B)
PMAJ: 107199198
CCAE: 111927477(PTK2B)
FPG: 101919541(PTK2B)
FCH: 102058792(PTK2B)
CLV: 102085172(PTK2B)
EGZ: 104132028(PTK2B)
NNI: 104014715(PTK2B)
ACUN: 113478314(PTK2B)
AAM: 106486362(PTK2B)
ASN: 102383255(PTK2B)
AMJ: 102569140(PTK2B)
CPOO: 109311565(PTK2B)
PSS: 102461932(PTK2B)
CMY: 102944545(PTK2B)
CPIC: 101946809(PTK2B)
TST: 117875441(PTK2B)
CABI: 116830885(PTK2B)
ACS: 100563957(ptk2b)
PVT: 110089495(PTK2B)
PBI: 103053129(PTK2B)
PMUR: 107293495(PTK2B)
TSR: 106543337
PGUT: 117667683(PTK2B)
PMUA: 114594952(PTK2B)
ZVI: 118082945(PTK2B)
GJA: 107111937(PTK2B)
XLA: 108717254(ptk2b.L) 108718305(ptk2b.S)
XTR: 496459(ptk2b)
NPR: 108801309
DRE: 245950(ptk2bb) 557258(ptk2ba)
SRX: 107707077 107733482(ptk2b)
PHYP: 113538681(ptk2b) 113545212
AMEX: 103031863 103036889(ptk2b)
EEE: 113572664(ptk2b) 113573003
TRU: 101066596(ptk2b) 101067972
LCO: 104922431(ptk2b) 104929121
NCC: 104964448(ptk2b)
ELY: 117255568 117270872(ptk2bb)
SLUC: 116044716 116066076(ptk2bb)
ECRA: 117939207 117961384(ptk2bb)
PFLV: 114550829 114572960(ptk2b)
GAT: 120808070(ptk2bb) 120824977
CUD: 121506250 121521567(ptk2bb)
MZE: 101466145 101469888(ptk2b)
ONL: 100691138(ptk2b) 100702843
OAU: 116314090(ptk2bb) 116327901
OLA: 101166779 101168007(ptk2b)
OML: 112138372 112157942(ptk2bb)
XMA: 102220254(ptk2b) 102237728
XCO: 114137677 114158618(ptk2b)
CVG: 107083800(ptk2b) 107092212
CTUL: 119785101(ptk2bb) 119793630
NFU: 107380902 107397038(ptk2b)
KMR: 108242464(ptk2bb) 108244129
ALIM: 106525285(ptk2b) 106529652
AOCE: 111585687 111587153(ptk2b)
XGL: 120788723(ptk2bb) 120798377
HCQ: 109520887 109524920(ptk2b)
BPEC: 110166006 110175523(ptk2b)
OTW: 112262237
LOC: 102695443(ptk2b)
PSPA: 121316233 121317355(ptk2ba)
LCM: 102364762(PTK2B)
EPA: 110254117
 » show all
Reference
PMID:7544443
  Authors
Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J
  Title
Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions.
  Journal
Nature 376:737-45 (1995)
DOI:10.1038/376737a0
  Sequence
[hsa:2185]
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