KEGG   ORTHOLOGY: K06051
Entry
K06051                      KO                                     

Name
DLL
Definition
delta
Pathway
ko01522  Endocrine resistance
ko04330  Notch signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko05200  Pathways in cancer
ko05224  Breast cancer
Disease
H00517  Spondylocostal dysostosis
H01413  Adams-Oliver syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    K06051  DLL; delta
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K06051  DLL; delta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06051  DLL; delta
  09162 Cancer: specific types
   05224 Breast cancer
    K06051  DLL; delta
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K06051  DLL; delta
Genes
HSA: 10683(DLL3) 28514(DLL1) 54567(DLL4)
PTR: 453344(DLL4) 465121(DLL1) 736571(DLL3)
PPS: 100973086(DLL1) 100981817(DLL4) 100989211(DLL3)
GGO: 101123716(DLL4) 101126422(DLL3) 101154591(DLL1)
PON: 100436112(DLL3) 100436254(DLL1) 100437589(DLL4)
NLE: 100587621(DLL4) 100592674(DLL3) 100606767(DLL1)
MCC: 697453(DLL3) 704898(DLL4) 714731(DLL1)
MCF: 102115332(DLL3) 102125764(DLL4) 102145271(DLL1)
CSAB: 103234675(DLL3) 103240985(DLL1) 103245808(DLL4)
RRO: 104666892(DLL4) 104674405(DLL1) 104676143(DLL3)
RBB: 108539082(DLL3) 108541284(DLL1) 108544357(DLL4)
CJC: 100398335(DLL3) 100403776(DLL1) 100408189(DLL4)
SBQ: 101036391(DLL3) 101041321(DLL1) 101044427(DLL4)
MMU: 13388(Dll1) 13389(Dll3) 54485(Dll4)
MCAL: 110283771(Dll1) 110284642(Dll4) 110298934(Dll3)
MPAH: 110318243(Dll4) 110326973(Dll3) 110338215(Dll1)
RNO: 114125(Dll3) 311332(Dll4) 84010(Dll1)
MUN: 110550579(Dll4) 110561125(Dll1) 110564728(Dll3)
CGE: 100750697(Dll1) 100763048(Dll4) 100773804(Dll3)
NGI: 103742345(Dll1) 103744923(Dll4) 103750746(Dll3)
HGL: 101698853(Dll1) 101721317(Dll4) 101725599(Dll3)
CCAN: 109694309(Dll4)
OCU: 100339893(DLL3) 100344124(DLL1) 100352191(DLL4)
TUP: 102468123(DLL1) 102479901(DLL3) 102480910(DLL4)
CFA: 100688936(DLL1) 484508(DLL3) 607575(DLL4)
VVP: 112919960(DLL4) 112925211(DLL1) 112928298(DLL3)
AML: 100468026(DLL3) 100472990(DLL4) 100484708(DLL1)
UMR: 103660784(DLL1) 103661087(DLL3) 103673543(DLL4)
UAH: 113242017(DLL4) 113243222(DLL3) 113247092(DLL1)
ORO: 101367445(DLL4) 101379005(DLL3) 101382088(DLL1)
FCA: 101083683(DLL1) 101086978(DLL4) 101095456(DLL3)
PTG: 102951103(DLL1) 102952034(DLL3) 102961766(DLL4)
PPAD: 109245470(DLL1) 109256657(DLL3) 109263136(DLL4)
AJU: 106968571(DLL4) 106978660(DLL1) 106979590(DLL3)
BTA: 505993(DLL3) 518746(DLL4) 788775(DLL1)
BOM: 102272154(DLL3) 102277712(DLL4) 102283833(DLL1)
BIU: 109564135(DLL1) 109564955(DLL4) 109572127(DLL3)
BBUB: 102396215(DLL3) 102396446 102409006(DLL4) 112587301(DLL1)
CHX: 102180396(DLL4) 102182594(DLL1) 102184186(DLL3)
OAS: 101116337(DLL3) 101117853(DLL1) 780478(DLL4)
SSC: 100152163(DLL4) 100520433(DLL3) 100620481(DLL1)
CFR: 102510495(DLL4) 102511280(DLL3) 102513087(DLL1)
CDK: 105093387(DLL3) 105093899(DLL1) 105096864(DLL4)
BACU: 103002651(DLL3) 103008745(DLL4) 103017665(DLL1)
LVE: 103070090(DLL3) 103072496(DLL4) 103082526(DLL1)
OOR: 101270732(DLL1) 101275938(DLL4) 101279638(DLL3)
DLE: 111167988(DLL1) 111180865(DLL3) 111181726(DLL4)
PCAD: 102978082(DLL1) 102993790(DLL4) 102994639(DLL3)
ECB: 100052876(DLL1) 100057073(DLL4) 100067648(DLL3)
EPZ: 103542262(DLL4) 103556273(DLL1) 103558860(DLL3)
EAI: 106841366(DLL4) 106843247(DLL3) 106846758(DLL1)
MYB: 102241481(DLL1) 102242880(DLL3) 102257976(DLL4)
MYD: 102752350(DLL4) 102756052(DLL3) 102758782(DLL1)
MNA: 107534146(DLL3) 107537014(DLL1) 107542965(DLL4)
HAI: 109383961(DLL4) 109391679(DLL1) 109395346(DLL3)
DRO: 112297307(DLL1) 112311496(DLL4) 112320023(DLL3)
PALE: 102882856(DLL3) 102891557(DLL4) 102892930(DLL1)
RAY: 107500164(DLL1) 107514489(DLL4) 107521802(DLL3)
MJV: 108392502(DLL4) 108394698(DLL3) 108395741(DLL1)
LAV: 100654838(DLL1) 100662144(DLL3) 100671694(DLL4)
MDO: 100014594(DLL3) 100032054(DLL4) 100032690(DLL1)
SHR: 100919868(DLL1) 100933691(DLL4)
PCW: 110197978(DLL1) 110198245(DLL3) 110223699(DLL4)
OAA: 100084879(DLL4) 100088465(DLL1) 100088980(DLL3)
GGA: 395820(DLL1) 423208(DLL4)
MGP: 100540793(DLL4) 100544223(DLL1)
CJO: 107311443(DLL1) 107314835(DLL4)
NMEL: 110389122(DLL3) 110395686(DLL1) 110401602(DLL4)
APLA: 101792399(DLL4) 101803503(DLL1)
ACYG: 106043235(DLL4) 106044560(DLL1)
TGU: 100221955(DLL4) 100230776(DLL1) 115493173
LSR: 110468920(DLL1) 110472092(DLL4)
SCAN: 103818491(DLL1) 103826666(DLL4)
GFR: 102044857(DLL1) 102045124(DLL4)
FAB: 101814466(DLL1) 101819885(DLL4)
PHI: 102103426(DLL4) 102104688(DLL1)
PMAJ: 107201971(DLL1) 107206354(DLL4)
CCAE: 111926906(DLL1) 111930070(DLL4)
CCW: 104684457(DLL1) 104688175(DLL4)
ETL: 114059321(DLL4) 114064635(DLL1)
FPG: 101921686(DLL1) 101924204(DLL4)
FCH: 102050284(DLL1) 102059352(DLL4)
CLV: 102085870(DLL1) 102096537(DLL4)
EGZ: 104127561(DLL4) 104131071(DLL1)
NNI: 104018286(DLL1) 104020455(DLL4)
ACUN: 113477890(DLL1) 113480800(DLL4)
PADL: 103912860(DLL4) 103921304(DLL1)
AAM: 106487338(DLL1) 106498111(DLL4)
ASN: 102385762(DLL4) 102388492(DLL1)
AMJ: 102558081(DLL4) 102570015(DLL1)
PSS: 102446756(DLL1) 102452410(DLL4) 102459507
CMY: 102940211(DLL4) 102940998(DLL1) 102941591
CPIC: 101934714(DLL1) 101947678(DLL3) 101947721(DLL4)
ACS: 100555876(dll4) 100562797(dll1) 100567881(dll3)
PVT: 110075677(DLL3) 110079034(DLL4) 110083057(DLL1)
PBI: 103049977(DLL3) 103054339(DLL4) 103059085(DLL1)
PMUR: 107282159(DLL4) 107290188(DLL1) 107291964
TSR: 106538555(DLL1) 106542323(DLL4)
PMUA: 114593989(DLL4) 114594359(DLL1) 114603098(DLL3)
GJA: 107106377 107113466(DLL1) 107126022(DLL4)
XLA: 100337564(dll1.L) 108699270(dll4.L) 108699846 108704436 108705808 108717842(dll1.S) 379238(dlc.L)
XTR: 100101697(dll1) 100124798(dlc) 100489166(dll4)
NPR: 108794905(DLL4) 108798958(DLL1) 108804956(DLL3)
DRE: 30120(dlc) 30131(dla) 30138(dld) 30141(dlb) 563920(dll4)
SFM: 108919649(dll4) 108928772(dll3) 108932854(dll1)
LCM: 102346486(DLL1) 102347129(DLL3) 102366714(DLL4)
CMK: 103171859(dll1) 103190052
CIN: 778573(delta)
SPU: 373299(delta)
APLC: 110975145
SKO: 100303546(delta)
DME: Dmel_CG3619(Dl)
DER: 6553813
DSE: 6619086
DSI: Dsimw501_GD20120(Dsim_Dl)
DAN: 6501241
DSR: 110188576
DPE: 6594106
DMN: 108156309
DWI: 6651668
DAZ: 108609050
DNV: 108660337
DHE: 111596203
DVI: 6630536
MDE: 101891014
LCQ: 111678722
AAG: 5580156
AALB: 109411919
AME: 410351
BIM: 100746813
BTER: 100648761
CCAL: 108624094
OBB: 114873921
SOC: 105201510
MPHA: 105835536
AEC: 105146842
ACEP: 105625269
PBAR: 105431145
VEM: 105563731
HST: 105191219
DQU: 106747935
CFO: 105256389
LHU: 105671450
PGC: 109851708
OBO: 105287804
PCF: 106784596
NVI: 100118327
CSOL: 105367938
MDL: 103578783
TCA: 658619
DPA: 109538020
ATD: 109608377
NVL: 108567092
BMOR: 100188969(Dl)
BMAN: 114247036
PMAC: 106707723
PRAP: 110992463
HAW: 110373726
TNL: 113499279
API: 100160703
DNX: 107161344
AGS: 114129086
RMD: 113553158
BTAB: 109039052
CLEC: 106669577
ZNE: 110839762
FCD: 110843110
PVM: 113815864
TUT: 107365922
DPTE: 113792182
PCAN: 112559995
OBI: 106868910
LAK: 106161319
SHX: MS3_02770
EPA: 110250715
ADF: 107357841
AMIL: 114962868
PDAM: 113681489
SPIS: 111329102
AQU: 100638185(Delta5)
 » show all
Reference
  Authors
Shutter JR, Scully S, Fan W, Richards WG, Kitajewski J, Deblandre GA, Kintner CR, Stark KL
  Title
Dll4, a novel Notch ligand expressed in arterial endothelium.
  Journal
Genes Dev 14:1313-8 (2000)
DOI:10.1101/gad.14.11.1313
  Sequence
[hsa:54567]
Reference
  Authors
Yoneya T, Tahara T, Nagao K, Yamada Y, Yamamoto T, Osawa M, Miyatani S, Nishikawa M
  Title
Molecular cloning of delta-4, a new mouse and human Notch ligand.
  Journal
J Biochem 129:27-34 (2001)
DOI:10.1093/oxfordjournals.jbchem.a002832
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