KEGG   ORTHOLOGY: K06225
Entry
K06225                      KO                                     

Name
PTCH1
Definition
patched 1
Pathway
map04024  cAMP signaling pathway
map04340  Hedgehog signaling pathway
map04341  Hedgehog signaling pathway - fly
map04360  Axon guidance
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05217  Basal cell carcinoma
Disease
H00039  Basal cell carcinoma
H00267  Holoprosencephaly
H00895  Basal cell nevus syndrome
H01667  Medulloblastoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    K06225  PTCH1; patched 1
   04341 Hedgehog signaling pathway - fly
    K06225  PTCH1; patched 1
   04024 cAMP signaling pathway
    K06225  PTCH1; patched 1
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K06225  PTCH1; patched 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06225  PTCH1; patched 1
   05205 Proteoglycans in cancer
    K06225  PTCH1; patched 1
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    K06225  PTCH1; patched 1
Other DBs
GO: 0005119 0008158
TC: 2.A.6.6.2 2.A.6.6.13
Genes
HSA: 5727(PTCH1)
PTR: 465254(PTCH1)
PPS: 100970040(PTCH1)
GGO: 101138988(PTCH1)
NLE: 100581789(PTCH1)
MCC: 718751(PTCH1)
MCF: 102121818(PTCH1)
CSAB: 103219825(PTCH1)
CATY: 105579525(PTCH1)
PANU: 101018770(PTCH1)
RRO: 104669119(PTCH1)
RBB: 108529288(PTCH1)
TFN: 117098271(PTCH1)
PTEH: 111521696(PTCH1)
CJC: 100410387(PTCH1)
SBQ: 101048276(PTCH1)
MMUR: 105862135(PTCH1)
MMU: 19206(Ptch1)
MCAL: 110307775(Ptch1)
MPAH: 110333595(Ptch1)
RNO: 89830(Ptch1)
MCOC: 116081424(Ptch1)
MUN: 110551759(Ptch1)
CGE: 100763926(Ptch1)
PLEU: 114708424(Ptch1)
NGI: 103751618
HGL: 101711146(Ptch1)
CCAN: 109683424(Ptch1)
OCU: 100345046(PTCH1)
TUP: 102471693(PTCH1)
CFA: 484137(PTCH1)
VVP: 112908731(PTCH1)
VLG: 121484106(PTCH1)
AML: 100475966(PTCH1)
UMR: 103682234(PTCH1)
UAH: 113269779(PTCH1)
ORO: 101379447(PTCH1)
ELK: 111139086
MPUF: 101680366(PTCH1)
EJU: 114223388(PTCH1)
MLX: 118023339(PTCH1)
FCA: 101085077(PTCH1)
PTG: 102972008(PTCH1)
PPAD: 109251660
AJU: 106971452(PTCH1)
HHV: 120240837(PTCH1)
BTA: 520994(PTCH1)
BOM: 102283867(PTCH1)
BIU: 109563237(PTCH1)
BBUB: 102389314(PTCH1)
CHX: 102187048(PTCH1)
OAS: 101112193(PTCH1)
ODA: 120867037(PTCH1)
SSC: 100627504(PTCH1)
CFR: 102517641(PTCH1)
CDK: 105084688(PTCH1)
BACU: 103004681(PTCH1)
LVE: 103086592(PTCH1)
OOR: 101284461(PTCH1)
DLE: 111166803(PTCH1)
PCAD: 102973233(PTCH1)
ECB: 100033936(PTCH1)
EPZ: 103551335(PTCH1)
EAI: 106841108(PTCH1)
MYB: 102254605(PTCH1)
MYD: 102770033(PTCH1)
MMYO: 118667639(PTCH1)
MNA: 107532314(PTCH1)
HAI: 109396730(PTCH1)
DRO: 112302742(PTCH1)
SHON: 118993710(PTCH1)
AJM: 119046072(PTCH1)
MMF: 118629803(PTCH1)
PALE: 102884350(PTCH1)
RAY: 107518086(PTCH1)
MJV: 108383415(PTCH1)
TOD: 119232087(PTCH1)
LAV: 100676123(PTCH1)
TMU: 101346502
MDO: 100014019(PTCH1)
SHR: 100934585(PTCH1)
PCW: 110197646(PTCH1)
OAA: 100079214(PTCH1)
GGA: 395806(PTCH1)
PCOC: 116238484(PTCH1)
CJO: 107306269(PTCH1)
NMEL: 110389731(PTCH1)
APLA: 101802613(PTCH1)
ACYG: 106047348(PTCH1)
TGU: 100224767(PTCH1)
LSR: 110471014(PTCH1)
SCAN: 103822966(PTCH1)
PMOA: 120511975(PTCH1)
GFR: 102033626(PTCH1)
FAB: 101813866(PTCH1)
PHI: 102104157(PTCH1)
PMAJ: 107198215(PTCH1)
CCAE: 111941810(PTCH1)
CCW: 104692014(PTCH1)
ETL: 114055235(PTCH1) 114071695
FPG: 101915344(PTCH1)
FCH: 102054107(PTCH1)
CLV: 102096921(PTCH1)
EGZ: 104125901(PTCH1)
NNI: 104011757(PTCH1) 104022796
ACUN: 113490118(PTCH1)
PADL: 103920407(PTCH1)
AAM: 106489077(PTCH1) 106492944
ASN: 102382615(PTCH1)
AMJ: 102570023(PTCH1)
CPOO: 109323424(PTCH1)
GGN: 109297535(PTCH1)
PSS: 102445339(PTCH1)
CMY: 102936563(PTCH1)
CPIC: 101942144(PTCH1)
TST: 117878979(PTCH1)
CABI: 116821162(PTCH1)
ACS: 100561354(ptch1)
PVT: 110084178(PTCH1)
PBI: 103057988(PTCH1)
PMUR: 107294604(PTCH1)
TSR: 106537500(PTCH1)
PGUT: 117661370(PTCH1)
PMUA: 114606550(PTCH1)
ZVI: 118076713(PTCH1)
GJA: 107111660(PTCH1)
XLA: 108714691(ptch1.L) 398215(ptch1.S)
XTR: 100492061(ptch1)
NPR: 108788147(PTCH1)
DRE: 30189(ptch1)
SGH: 107594528 107602819(ptch1)
IPU: 108265905(ptch1)
PHYP: 113526490(ptch1)
AMEX: 103030480(ptch1)
EEE: 113591305(ptch1)
TRU: 101065775(ptch1)
LCO: 104920679(ptch1)
NCC: 104961260
ELY: 117252668(ptch1)
PLEP: 121944402(ptch1)
SLUC: 116054025(ptch1)
ECRA: 117944979(ptch1)
PFLV: 114555949(ptch1)
GAT: 120830892(ptch1)
MSAM: 119891957(ptch1)
CUD: 121509987(ptch1)
MZE: 101469910(ptch1)
ONL: 100700194(ptch1)
OAU: 116311163(ptch1)
OLA: 101166055(ptch1)
OML: 112148505(ptch1)
XMA: 102216370(ptch1)
XCO: 114154713(ptch1)
XHE: 116729898(ptch1)
PRET: 103470155(ptch1)
CVG: 107098237(ptch1)
CTUL: 119781110(ptch1)
NFU: 107394090(ptch1)
KMR: 108244808(ptch1)
ALIM: 106534574(ptch1)
AOCE: 111576662(ptch1)
POV: 109639307(ptch1)
LCF: 108882648(ptch1)
SDU: 111236154(ptch1)
SLAL: 111644627(ptch1)
XGL: 120805768(ptch1)
HCQ: 109520682(ptch1)
BPEC: 110167016(ptch1)
MALB: 109956558(ptch1)
SASA: 106580561 106585152(ptch1)
OMY: 110525920(ptch1) 110535101
SALP: 111957566 111974363(ptch1)
ELS: 105014106(ptch1)
SFM: 108938420(ptch1)
PKI: 111836962(ptch2) 111839228(ptch1)
LOC: 102685711(ptch1)
LCM: 102356323(PTCH1)
CMK: 103182828(ptch1)
RTP: 109910728(ptch1)
CIN: 778726
SPU: 593924
APLC: 110987218
SKO: 100329100
DME: Dmel_CG2411(ptc)
DER: 6542563
DSE: 6608211
DSI: Dsimw501_GD15378(Dsim_GD15378)
DAN: 6495223
DSR: 110189362
DPE: 6590429
DMN: 108159751
DWI: 6640513
DAZ: 108616937
DNV: 115564864
DHE: 111597108
DVI: 6625655
MDE: 101891704
LCQ: 111683638
ACOZ: 120955324
AARA: 120902652
AAG: 5576239
CPII: 120431028
AME: 100576449
ACER: 108001413
BIM: 100744503
BTER: 100646247
CCAL: 108624051
OBB: 114876032
MGEN: 117228111
NMEA: 116426590
CGIG: 122398819
SOC: 105198669
MPHA: 105840112
AEC: 105150438
ACEP: 105627352
PBAR: 105425643
VEM: 105560263
HST: 105191688
DQU: 106743715
CFO: 105250911
FEX: 115243445
LHU: 105677457
PGC: 109854133
OBO: 105286843
PCF: 106789111
NVI: 100120760(Ptc)
CSOL: 105367356
MDL: 103572394
TCA: 656155(Ptc)
DPA: 109537974
ATD: 109595085
AGB: 108914707
NVL: 108558276
APLN: 108733784
PPYR: 116171922
OTU: 111419197
BMOR: 101743039
MSEX: 115443752
BANY: 112052161
PMAC: 106709248
PPOT: 106100393
PXU: 106124393
PRAP: 111003839
ZCE: 119829287
HAW: 110377759
TNL: 113501710
PXY: 105397535
API: 100158939
DNX: 107167310
AGS: 114121827
RMD: 113550312
BTAB: 109034039
DCI: 103524958
CLEC: 106663373
NLU: 111063259
ZNE: 110839560
CSEC: 111874295
FCD: 110846444
DPX: DAPPUDRAFT_40041(PTC)
PVM: 113816612
HAME: 121859739
EAF: 111713880
DSV: 119433524
RSAN: 119405022
RMP: 119181799
TUT: 107361254
DPTE: 113791049
PTEP: 107440240
SDM: 118192261
CEL: CELE_Y110A2AL.8(ptc-3) CELE_ZK675.1(ptc-1)
CBR: CBG03294 CBG19582(Cbr-ptc-3)
BMY: BM_BM12292(Bma-ptc-3) BM_BM3500(Bm3500)
TSP: Tsp_05634
PCAN: 112573863
BGT: 106065455
CRG: 105326154
MYI: 110466639
PMAX: 117325604
OBI: 106878151
LAK: 106165040
EGL: EGR_02418
NVE: 5520323
EPA: 110255116
ADF: 107357180
DGT: 114523314
HMG: 101240194
 » show all
Reference
PMID:8647801
  Authors
Hahn H, Christiansen J, Wicking C, Zaphiropoulos PG, Chidambaram A, Gerrard B, Vorechovsky I, Bale AE, Toftgard R, Dean M, Wainwright B
  Title
A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities.
  Journal
J Biol Chem 271:12125-8 (1996)
DOI:10.1074/jbc.271.21.12125
  Sequence
[hsa:5727] [mmu:19206]
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