KEGG   ORTHOLOGY: K06225Help
Entry
K06225                      KO                                     

Name
PTCH1
Definition
patched 1
Pathway
ko04024  cAMP signaling pathway
ko04340  Hedgehog signaling pathway
ko04341  Hedgehog signaling pathway - fly
ko04360  Axon guidance
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
Disease
H00039  Basal cell carcinoma
H00267  Holoprosencephaly
H00895  Basal cell nevus syndrome
H01667  Medulloblastoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    K06225  PTCH1; patched 1
   04341 Hedgehog signaling pathway - fly
    K06225  PTCH1; patched 1
   04024 cAMP signaling pathway
    K06225  PTCH1; patched 1
 09150 Organismal Systems
  09158 Development
   04360 Axon guidance
    K06225  PTCH1; patched 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06225  PTCH1; patched 1
   05205 Proteoglycans in cancer
    K06225  PTCH1; patched 1
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    K06225  PTCH1; patched 1
BRITE hierarchy
Other DBs
GO: 0005119 0008158
Genes
HSA: 5727(PTCH1)
PTR: 465254(PTCH1)
PPS: 100970040(PTCH1)
GGO: 101138988(PTCH1)
PON: 100432417(PTCH1)
NLE: 100581789(PTCH1)
MCC: 718751(PTCH1)
MCF: 102121818(PTCH1)
CSAB: 103219825(PTCH1)
RRO: 104669119(PTCH1)
RBB: 108529288(PTCH1)
CJC: 100410387(PTCH1)
SBQ: 101048276(PTCH1)
MMU: 19206(Ptch1)
MCAL: 110307775(Ptch1)
MPAH: 110333595(Ptch1)
RNO: 89830(Ptch1)
MUN: 110551759(Ptch1)
CGE: 100763926(Ptch1)
NGI: 103751618
HGL: 101711146(Ptch1)
CCAN: 109683424(Ptch1)
OCU: 100345046(PTCH1)
TUP: 102471693(PTCH1)
CFA: 484137(PTCH1)
VVP: 112908731(PTCH1)
AML: 100475966(PTCH1)
UMR: 103682234(PTCH1)
UAH: 113269779(PTCH1)
ORO: 101379447(PTCH1)
FCA: 101085077(PTCH1)
PTG: 102972008(PTCH1)
AJU: 106971452(PTCH1)
BTA: 520994(PTCH1)
BOM: 102283867(PTCH1)
BIU: 109563237(PTCH1)
BBUB: 102389314(PTCH1)
PHD: 102339762(PTCH1)
CHX: 102187048(PTCH1)
OAS: 101112193(PTCH1)
SSC: 100627504(PTCH1)
CFR: 102517641(PTCH1)
CDK: 105084688(PTCH1)
BACU: 103004681(PTCH1)
LVE: 103086592(PTCH1)
OOR: 101284461(PTCH1)
DLE: 111166803(PTCH1)
ECB: 100033936(PTCH1)
EPZ: 103551335(PTCH1)
EAI: 106841108(PTCH1)
MYB: 102254605(PTCH1)
MYD: 102770033(PTCH1)
MNA: 107532314(PTCH1)
HAI: 109396730(PTCH1)
RSS: 109434756(PTCH1)
DRO: 112302742(PTCH1)
PALE: 102884350(PTCH1)
LAV: 100676123(PTCH1)
TMU: 101346502
MDO: 100014019(PTCH1)
SHR: 100934585(PTCH1)
PCW: 110197646(PTCH1)
OAA: 100079214(PTCH1)
GGA: 395806(PTCH1)
CJO: 107306269(PTCH1)
APLA: 101802613(PTCH1)
ACYG: 106047348(PTCH1)
TGU: 100224767(PTCH1)
LSR: 110471014(PTCH1)
SCAN: 103822966(PTCH1)
GFR: 102033626(PTCH1) 102044667
FAB: 101813866(PTCH1)
PHI: 102104157(PTCH1)
PMAJ: 107198215(PTCH1)
CCAE: 111941810(PTCH1)
CCW: 104692014(PTCH1)
FPG: 101915344(PTCH1)
FCH: 102054107(PTCH1)
CLV: 102096921(PTCH1)
EGZ: 104125901(PTCH1)
NNI: 104011757(PTCH1) 104022796
ACUN: 113490118(PTCH1)
ASN: 102382615(PTCH1)
AMJ: 102570023(PTCH1)
PSS: 102445339(PTCH1)
CMY: 102936563(PTCH1)
CPIC: 101942144(PTCH1)
ACS: 100561354(ptch1)
PVT: 110084178(PTCH1)
PBI: 103057988(PTCH1)
PMUR: 107294604(PTCH1)
GJA: 107111660(PTCH1)
XLA: 100191013(ptch2.L) 108714691(Xptch-1') 398215(ptch1.L)
XTR: 100492061(ptch1) 100492958(ptch2)
NPR: 108788147(PTCH1) 108802368(PTCH2)
DRE: 30181(ptch2) 30189(ptch1)
IPU: 108265905(ptch1) 108267803(ptch2)
PHYP: 113526490(ptch1) 113540269(ptch2)
AMEX: 103021456 103030480(ptch1)
EEE: 113588043 113590220(ptch2) 113591305(ptch1)
TRU: 101065775(ptch1) 101078434(ptch2)
LCO: 104920679(ptch1) 104936684(ptch2)
MZE: 101469910(ptch1) 101474729(ptch2)
OLA: 101159383(ptch2) 101166055(ptch1)
XMA: 102216370(ptch1) 102217654(ptch2)
XCO: 114146891(ptch2) 114154713(ptch1)
PRET: 103470155(ptch1) 103479622(ptch2)
NFU: 107383993(ptch2) 107394090(ptch1)
KMR: 108239668(ptch2) 108244808(ptch1)
LCF: 108882648(ptch1) 108883493(ptch2)
SDU: 111228875(ptch2) 111236154(ptch1)
HCQ: 109516881(ptch2) 109520682(ptch1)
BPEC: 110159317(ptch2) 110167016(ptch1)
MALB: 109956558(ptch1) 109957709(ptch2)
ELS: 105014106(ptch1) 105022690(ptch2)
SFM: 108934948(ptch2) 108938420(ptch1)
PKI: 111836962(ptch2) 111839228(ptch1)
LCM: 102356323(PTCH1)
CMK: 103182823(ptch2) 103182828(ptch1)
BFO: BRAFLDRAFT_225229(PTCH1)
CIN: 778726
SPU: 593924
APLC: 110987218
SKO: 100329100
DME: Dmel_CG2411(ptc)
DER: 6542563
DSI: Dsimw501_GD15378(Dsim_GD15378)
DWI: 6640513
DAZ: 108616937
DHE: 111597108
MDE: 101891704
AAG: 5576239
AME: 100576449
BTER: 100646247
SOC: 105198669
MPHA: 105840112
AEC: 105150438
ACEP: 105627352
PBAR: 105425643
HST: 105191688
DQU: 106743715
CFO: 105250911
LHU: 105677457
PGC: 109854133
OBO: 105286843
PCF: 106789111
NVI: 100120760(Ptc)
MDL: 103572394
TCA: 656155(Ptc)
DPA: 109537974
NVL: 108558276
BMOR: 101743039
PMAC: 106709248
PRAP: 111003839
HAW: 110377759
TNL: 113501710
PXY: 105397535
API: 100158939
DNX: 107167310
AGS: 114121827
CLEC: 106663373
ZNE: 110839560
FCD: 110846444
DPX: DAPPUDRAFT_40041(PTC)
TUT: 107361254
DPTE: 113791049
CEL: CELE_F21H12.4(ptc-2) CELE_Y110A2AL.8(ptc-3) CELE_ZK675.1(ptc-1)
CBR: CBG03294 CBG19582(Cbr-ptc-3)
TSP: Tsp_05634
PCAN: 112573863
CRG: 105326154
MYI: 110466639
OBI: 106878151
LAK: 106165040
SHX: MS3_02424
EGL: EGR_02418
EPA: 110255116
HMG: 101240194
CRE: CHLREDRAFT_154085(SSD2)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8647801
  Authors
Hahn H, Christiansen J, Wicking C, Zaphiropoulos PG, Chidambaram A, Gerrard B, Vorechovsky I, Bale AE, Toftgard R, Dean M, Wainwright B
  Title
A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities.
  Journal
J Biol Chem 271:12125-8 (1996)
DOI:10.1074/jbc.271.21.12125
  Sequence
[hsa:5727] [mmu:19206]
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