KEGG   ORTHOLOGY: K06272
Entry
K06272                      KO                                     

Name
ILK
Definition
integrin-linked kinase [EC:2.7.11.1]
Pathway
ko03320  PPAR signaling pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko05100  Bacterial invasion of epithelial cells
ko05131  Shigellosis
ko05213  Endometrial cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06272  ILK; integrin-linked kinase
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K06272  ILK; integrin-linked kinase
  09158 Development and regeneration
   04360 Axon guidance
    K06272  ILK; integrin-linked kinase
 09160 Human Diseases
  09162 Cancer: specific types
   05213 Endometrial cancer
    K06272  ILK; integrin-linked kinase
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K06272  ILK; integrin-linked kinase
   05100 Bacterial invasion of epithelial cells
    K06272  ILK; integrin-linked kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06272  ILK; integrin-linked kinase
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06272  ILK; integrin-linked kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06272  ILK; integrin-linked kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: TKL group
  MLK family
   K06272  ILK; integrin-linked kinase
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    K06272  ILK; integrin-linked kinase
Genes
HSA: 3611(ILK)
PTR: 748941(ILK)
PPS: 100968361(ILK)
GGO: 101148955(ILK)
PON: 100173674(ILK)
NLE: 100598379(ILK)
MCC: 709944(ILK)
MCF: 102126017(ILK)
CSAB: 103241301(ILK)
RRO: 104678304(ILK)
RBB: 108543237(ILK)
CJC: 100406751(ILK)
SBQ: 101029493(ILK)
MMU: 16202(Ilk)
MCAL: 110299376(Ilk)
MPAH: 110335784(Ilk)
RNO: 170922(Ilk)
MUN: 110559582(Ilk)
CGE: 100689388(Ilk)
NGI: 103737567(Ilk)
HGL: 101706216(Ilk)
CCAN: 109696308(Ilk)
OCU: 100355759(ILK)
TUP: 102473651(ILK)
CFA: 476836(ILK)
VVP: 112910864(ILK)
AML: 100473650(ILK)
UMR: 103681403(ILK)
UAH: 113245818(ILK)
ORO: 101363175(ILK) 101375473
FCA: 101092790(ILK)
PTG: 102967313(ILK)
PPAD: 109261635 109271076(ILK)
AJU: 106981151(ILK)
BTA: 540207(ILK)
BOM: 102280066(ILK)
BIU: 109569757(ILK)
BBUB: 102403164(ILK)
CHX: 102177259(ILK)
OAS: 100913157(ILK)
SSC: 100623256(ILK)
CFR: 102511818(ILK)
CDK: 105097907(ILK)
BACU: 103018082(ILK)
LVE: 103083507(ILK)
OOR: 101289017(ILK)
DLE: 111169176(ILK)
PCAD: 102995328(ILK)
ECB: 100070066(ILK)
EPZ: 103553532(ILK)
EAI: 106838181(ILK)
MYB: 102248130(ILK)
MYD: 102764668(ILK)
MNA: 107540507(ILK)
HAI: 109376531(ILK)
DRO: 112312782(ILK)
PALE: 102887513(ILK)
RAY: 107504363(ILK)
MJV: 108384232(ILK)
LAV: 100666830(ILK)
TMU: 101346618
MDO: 100023322(ILK)
SHR: 100915068(ILK)
PCW: 110200481(ILK)
OAA: 114807332(ILK)
GGA: 374018(ILK)
MGP: 100548319(ILK)
CJO: 107308571(ILK)
NMEL: 110391748(ILK)
APLA: 101790559(ILK)
ACYG: 106049775(ILK)
TGU: 100228455(ILK)
LSR: 110474957(ILK)
SCAN: 103824410(ILK)
GFR: 102034600(ILK)
FAB: 101806205(ILK)
PHI: 102104711(ILK)
PMAJ: 107198962(ILK)
CCAE: 111943737(ILK)
CCW: 104698082(ILK)
ETL: 114069902(ILK)
FPG: 101919060(ILK)
FCH: 102050186(ILK)
CLV: 102094280(ILK)
EGZ: 104130615(ILK)
NNI: 104014876(ILK)
PADL: 103924867(ILK)
AAM: 106497742 106497745(ILK)
ASN: 102378418(ILK)
AMJ: 102559647(ILK)
PSS: 102443361(ILK)
CMY: 102931035(ILK)
CPIC: 101952498(ILK)
ACS: 100556484(ilk)
PVT: 110078157(ILK)
PBI: 103059609(ILK)
PMUR: 107288657(ILK)
TSR: 106541883(ILK)
PMUA: 114595166(ILK)
GJA: 107116953(ILK)
XLA: 444414 446640(ilk.S)
XTR: 100145644(ilk)
NPR: 108799886(ILK)
DRE: 393543(ilk)
SANH: 107685015 107701121(ilk)
SGH: 107556859(ilk)
IPU: 108277251(ilk)
PHYP: 113543442(ilk)
AMEX: 103042782(ilk)
EEE: 113581672(ilk)
TRU: 101064916(ilk) 101074511
NCC: 104947434 104952256(ilk)
MZE: 101477640 101485551(ilk)
XMA: 102225759(ilk) 102231522
XCO: 114133688(ilk) 114152747
PRET: 103474125 103475517(ilk)
CVG: 107087916 107099544(ilk)
ALIM: 106514119(ilk) 106529737
CSEM: 103378043(ilk) 103395087
LCF: 108876077(ilk) 108893604
SLAL: 111653646(ilk) 111666302
HCQ: 109509738 109527221(ilk)
SASA: 100194973(ilk) 106581335
ELS: 105023567(ilk)
SFM: 108921298(ilk) 108938337
PKI: 111838003 111856818(ilk)
LCM: 102365370(ILK)
CMK: 103172827(ilk)
BFO: 118419011
CIN: 100184368
APLC: 110979821
SKO: 100376887
DME: Dmel_CG10504(Ilk)
DER: 6546273
DSE: 6616413
DSI: Dsimw501_GD14943(Dsim_GD14943)
DAN: 6506935
DSR: 110189984
DPE: 6601164
DMN: 108153196
DWI: 6639079
DAZ: 108613105
DNV: 108651892
DHE: 111594364
DVI: 6623860
MDE: 101895541
LCQ: 111683614
AAG: 5575137
AALB: 109400747
AME: 413354
BIM: 100740129
BTER: 100646980
CCAL: 108631300
OBB: 114878048
SOC: 105200508
MPHA: 105831508
AEC: 105145197
ACEP: 105617817
PBAR: 105424315
VEM: 105568674
HST: 105184315
DQU: 106745964
CFO: 105256339
LHU: 105680032
PGC: 109857075
OBO: 105284326
PCF: 106790583
NVI: 100116422
CSOL: 105362293
MDL: 103572637
TCA: 655116
DPA: 109544881
ATD: 109599023
NVL: 108565932
BMOR: 101744627
PMAC: 106718907
PRAP: 110995055
HAW: 110373704
TNL: 113497766
API: 100163230
AGS: 114132415
RMD: 113551346
BTAB: 109040825
CLEC: 106664613
ZNE: 110836773
FCD: 110851117
PVM: 113807347
TUT: 107364041
DPTE: 113788984
CSCU: 111640873
PTEP: 107453285
CEL: CELE_C29F9.7(pat-4)
CBR: CBG00460 CBG15792(Cbr-pat-4)
BMY: Bm1_20815
PCAN: 112558900
CRG: 105340380
MYI: 110440402
OBI: 106868884
LAK: 106165827
SHX: MS3_10188
EGL: EGR_02061
ADF: 107342551
AMIL: 114965495
PDAM: 113670668
SPIS: 111339027
HMG: 100210366
AQU: 100634569
CPAP: 110807510
CIT: 102618062
TCC: 18590140
GRA: 105797919
GAB: 108455533
DZI: 111284273
EGR: 104423692
FVE: 101311832
RCN: 112165997
PPER: 18782708
PMUM: 103328659
PAVI: 110772024
MDM: 103405799
PXB: 103933348
ZJU: 107417087
RCU: 8265009
JCU: 105650432
HBR: 110658997
MESC: 110608500
POP: 18099408
PEU: 105123450
VVI: 100852545
SLY: 101249145
SPEN: 107009611
SOT: 102602873
NSY: 104245839
NTO: 104095079
NAU: 109234245
INI: 109151235
SIND: 105176138
OEU: 111367371
HAN: 110887685
LSV: 111909966
CCAV: 112515719
DCR: 108210573
AOF: 109829103
ATR: 105420183
SPAR: SPRG_21119
 » show all
Reference
PMID:8538749
  Authors
Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S
  Title
Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.
  Journal
Nature 379:91-6 (1996)
DOI:10.1038/379091a0
  Sequence
[hsa:3611]
Reference
  Authors
Fielding AB, Dobreva I, Dedhar S
  Title
Beyond focal adhesions: integrin-linked kinase associates with tubulin and regulates mitotic spindle organization.
  Journal
Cell Cycle 7:1899-906 (2008)
DOI:10.4161/cc.7.13.6204
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