KEGG   ORTHOLOGY: K06274
Entry
K06274                      KO                                     

Name
VASP
Definition
vasodilator-stimulated phosphoprotein
Pathway
ko04015  Rap1 signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04611  Platelet activation
ko04666  Fc gamma R-mediated phagocytosis
ko04670  Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K06274  VASP; vasodilator-stimulated phosphoprotein
   04022 cGMP-PKG signaling pathway
    K06274  VASP; vasodilator-stimulated phosphoprotein
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06274  VASP; vasodilator-stimulated phosphoprotein
   04530 Tight junction
    K06274  VASP; vasodilator-stimulated phosphoprotein
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K06274  VASP; vasodilator-stimulated phosphoprotein
   04666 Fc gamma R-mediated phagocytosis
    K06274  VASP; vasodilator-stimulated phosphoprotein
   04670 Leukocyte transendothelial migration
    K06274  VASP; vasodilator-stimulated phosphoprotein
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K06274  VASP; vasodilator-stimulated phosphoprotein
   04147 Exosome
    K06274  VASP; vasodilator-stimulated phosphoprotein
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     K06274  VASP; vasodilator-stimulated phosphoprotein
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06274  VASP; vasodilator-stimulated phosphoprotein
Genes
HSA: 7408(VASP)
PTR: 107969760(VASP)
PPS: 100986884(VASP)
GGO: 101129795(VASP)
PON: 100462324(VASP)
NLE: 100597154(VASP)
MCC: 716022(VASP)
MCF: 102137208(VASP)
CSAB: 103234868(VASP)
RRO: 104673438(VASP)
RBB: 108531097(VASP)
CJC: 100407817(VASP)
SBQ: 101049548(VASP)
MMU: 22323(Vasp)
MCAL: 110297879(Vasp)
MPAH: 110336413(Vasp)
RNO: 361517(Vasp)
MUN: 110551519(Vasp)
CGE: 100756352(Vasp)
NGI: 103749195(Vasp)
HGL: 101708295(Vasp)
CCAN: 109692391(Vasp)
OCU: 100349467(VASP)
TUP: 102495919(VASP)
CFA: 403936(VASP)
VVP: 112931355(VASP)
AML: 100478770(VASP)
UMR: 103657189(VASP)
UAH: 113243424(VASP)
ORO: 101378347(VASP)
ELK: 111160553
FCA: 101094805(VASP)
PTG: 102948970(VASP)
PPAD: 109253231(VASP)
AJU: 106973593(VASP)
BTA: 514902(VASP)
BOM: 102281273(VASP)
BIU: 109571760(VASP)
BBUB: 102391250(VASP)
CHX: 102189153(VASP)
OAS: 101113616(VASP)
SSC: 110261011(VASP)
CFR: 102508023(VASP)
CDK: 105095447(VASP)
BACU: 103012549(VASP)
LVE: 103073514(VASP)
OOR: 101285857(VASP)
DLE: 111180731(VASP)
PCAD: 102982276(VASP)
ECB: 100070851(VASP)
EPZ: 103566352(VASP)
EAI: 106843740(VASP)
MYB: 102261163(VASP)
MYD: 102751694(VASP)
MNA: 107536769(VASP)
HAI: 109374736(VASP)
DRO: 112312938(VASP)
PALE: 102892921(VASP)
RAY: 107515989(VASP)
MJV: 108386882 108392084(VASP)
LAV: 100674787(VASP)
TMU: 101341927
MDO: 103099139(VASP)
SHR: 100931658(VASP)
PCW: 110203322(VASP)
OAA: 100092830(VASP)
GGA: 107057642(VASP)
TGU: 115493161
PHI: 102104793(VASP)
AMJ: 102573405(VASP)
CPIC: 101950103(VASP)
PVT: 110075672(VASP)
PBI: 103051270(VASP)
PMUR: 107291638(VASP)
TSR: 106546148(VASP)
PMUA: 114603130(VASP)
XLA: 108700560 443914(vasp.L)
XTR: 493455(vasp)
DRE: 550487(vaspb) 555805(vaspa)
SGH: 107557842(vasp) 107565535
IPU: 108264341(vasp) 108276935
AMEX: 103041878(vasp)
EEE: 113581169
TRU: 101062854
LCO: 104921124
MZE: 101474454(vasp)
ONL: 100691610(vasp)
OLA: 101158044(vasp)
XMA: 102232643(vasp)
XCO: 114161570(vasp)
PRET: 103474744
CVG: 107101889(vasp)
NFU: 107380682
KMR: 108238199
ALIM: 106522167(vasp)
AOCE: 111569536(vasp)
CSEM: 103377622(vasp)
POV: 109634500(vasp)
LCF: 108879403(vasp)
SDU: 111222556
SLAL: 111651337
HCQ: 109512864
BPEC: 110161968(vasp)
MALB: 109960303(vasp)
OTW: 112267174
SALP: 111960673
ELS: 105006439 105011030(vasp)
SFM: 108927249
PKI: 111850600(vasp) 111860927
LCM: 102351560(VASP)
RTP: 109937854
SPU: 576114
APLC: 110974196
SKO: 100376569
 » show all
Reference
  Authors
Barzik M, Kotova TI, Higgs HN, Hazelwood L, Hanein D, Gertler FB, Schafer DA
  Title
Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins.
  Journal
J Biol Chem 280:28653-62 (2005)
DOI:10.1074/jbc.M503957200
Reference
PMID:7828592
  Authors
Haffner C, Jarchau T, Reinhard M, Hoppe J, Lohmann SM, Walter U
  Title
Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP.
  Journal
EMBO J 14:19-27 (1995)
DOI:10.1002/j.1460-2075.1995.tb06971.x
  Sequence
[hsa:7408]
LinkDB

KEGG   ORTHOLOGY: K05746
Entry
K05746                      KO                                     

Name
ENAH, MENA
Definition
enabled
Pathway
ko04015  Rap1 signaling pathway
ko04360  Axon guidance
ko04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K05746  ENAH, MENA; enabled
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05746  ENAH, MENA; enabled
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K05746  ENAH, MENA; enabled
Genes
HSA: 55740(ENAH)
PTR: 737268(ENAH)
PPS: 100980853(ENAH)
GGO: 101129354(ENAH)
PON: 100439142(ENAH)
NLE: 100595216(ENAH)
MCC: 700559(ENAH)
MCF: 102134090(ENAH)
CSAB: 103230007(ENAH)
RRO: 104668571(ENAH)
RBB: 108538743(ENAH)
CJC: 100410899(ENAH)
SBQ: 101030214(ENAH)
MMU: 13800(Enah)
MCAL: 110291342(Enah)
MPAH: 110321771(Enah)
RNO: 360891(Enah)
MUN: 110546662(Enah)
CGE: 100752970(Enah)
NGI: 103726260(Enah)
HGL: 101714860
CCAN: 109695259(Enah)
OCU: 100351936(ENAH)
TUP: 102498679(ENAH)
CFA: 490390(ENAH)
VVP: 112923566(ENAH)
AML: 100470718(ENAH)
UMR: 103669072(ENAH)
UAH: 113262910(ENAH)
ORO: 101374644(ENAH)
ELK: 111150887
FCA: 101085263(ENAH)
PTG: 102949275(ENAH)
PPAD: 109250166(ENAH)
AJU: 106968616(ENAH)
BTA: 513095(ENAH)
BOM: 102275161(ENAH)
BIU: 109570451(ENAH)
BBUB: 102403436(ENAH)
CHX: 102182617(ENAH)
OAS: 101104593(ENAH)
SSC: 100525245(ENAH)
CFR: 102510942(ENAH)
CDK: 105099759(ENAH)
BACU: 103004067(ENAH)
LVE: 103079491(ENAH)
OOR: 101284498(ENAH)
DLE: 111177516(ENAH)
PCAD: 102982219(ENAH)
ECB: 100057358(ENAH)
EPZ: 103556271(ENAH)
EAI: 106844554(ENAH)
MYB: 102241745(ENAH)
MYD: 102767765(ENAH)
MNA: 107543606(ENAH)
HAI: 109391467(ENAH)
DRO: 112318754(ENAH)
PALE: 102884415(ENAH)
MJV: 108403502(ENAH)
LAV: 100662950(ENAH)
TMU: 101353308
MDO: 100025688(ENAH)
SHR: 100926399(ENAH)
PCW: 110205525(ENAH)
OAA: 100081889(ENAH)
GGA: 374180(ENAH)
MGP: 100547100(ENAH)
CJO: 107311026(ENAH)
NMEL: 110395626(ENAH)
APLA: 101800557(ENAH)
ACYG: 106031539(ENAH)
TGU: 100231590(ENAH)
LSR: 110477502(ENAH)
SCAN: 103819286(ENAH) 115484916
GFR: 102044360(ENAH)
FAB: 101807561(ENAH)
PHI: 102114053(ENAH)
PMAJ: 107201932(ENAH)
CCAE: 111926265(ENAH)
CCW: 104685564(ENAH)
ETL: 114073699(ENAH)
FPG: 101915112(ENAH)
FCH: 102059973(ENAH)
CLV: 102088154(ENAH)
EGZ: 104134608(ENAH)
NNI: 104019275(ENAH)
ACUN: 113478078(ENAH)
PADL: 103925016(ENAH)
AAM: 106482711(ENAH)
ASN: 102369353(ENAH)
AMJ: 102562456(ENAH)
PSS: 102454611(ENAH)
CMY: 102934885
CPIC: 101937162(ENAH)
ACS: 100555779(enah)
PVT: 110075355(ENAH)
PBI: 103061600(ENAH)
PMUR: 107299157(ENAH)
TSR: 106553010(ENAH)
PMUA: 114594619(ENAH)
GJA: 107117862
XLA: 444086(enah.L) 446221(enah.S)
XTR: 100144977(enah)
NPR: 108787069(ENAH)
DRE: 541394(enah)
SRX: 107732530
SANH: 107690049(enah)
SGH: 107601525
CCAR: 109080220
IPU: 108258096(enah)
PHYP: 113546814(enah)
AMEX: 103032123(enah)
EEE: 113585129(enah)
TRU: 101076998(enah)
LCO: 104918341(enah)
MZE: 101485320
ONL: 100701304(enah)
OLA: 105357991(enah)
XMA: 102228581(enah)
XCO: 114158483(enah)
PRET: 103458038(enah)
CVG: 107093274(enah)
NFU: 107396010(enah)
KMR: 108246523(enah)
ALIM: 106532954
AOCE: 111583490(enah)
POV: 109632448(enah)
LCF: 108901778
SDU: 111240437(enah)
SLAL: 111661555(enah)
HCQ: 109524912(enah)
BPEC: 110169363(enah)
MALB: 109968074
SASA: 106607863(enah)
OTW: 112217643
SALP: 111954259
ELS: 105017791(enah)
SFM: 108925165(enah)
PKI: 111854049(enah)
LCM: 102359615
CMK: 103181606(enah)
RTP: 109916919
BFO: 118414090
DME: Dmel_CG15112(ena)
DSI: Dsimw501_GD11431(Dsim_GD11431) Dsimw501_GD14454(Dsim_GD14454)
DSR: 110184058
DPE: 113565103
DWI: 6646206
DHE: 111597962
MDE: 101897814
LCQ: 111680804
AAG: 5573842
AME: 727235
BIM: 100744390
BTER: 100647911
CCAL: 108627897
OBB: 114875617
SOC: 105193655
MPHA: 105829203
AEC: 105149285
PBAR: 105427129
VEM: 105562961
HST: 105190090
DQU: 106748717
CFO: 105257553
LHU: 105670398
PGC: 109860149
OBO: 105285786
PCF: 106783891
NVI: 100118626
CSOL: 105368998
MDL: 103576524
TCA: 658784
DPA: 109544847
ATD: 109596269
NVL: 108565936
BMOR: 101735452
BMAN: 114241088
PRAP: 110999375
TNL: 113505047
PXY: 105393446
API: 100164896
DNX: 107167503
AGS: 114124859
RMD: 113556244
BTAB: 109038868
CLEC: 106668727
SHX: MS3_06679
EPA: 110246156
BRP: 108871900
TASA: A1Q1_04966
ABV: AGABI2DRAFT120426(AGABI2DRAFT_120426)
DFA: DFA_02239
CPV: cgd6_3940
SMIN: v1.2.012634.t1(symbB.v1.2.012634.t1)
 » show all
Reference
  Authors
Boeda B, Briggs DC, Higgins T, Garvalov BK, Fadden AJ, McDonald NQ, Way M
  Title
Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding.
  Journal
Mol Cell 28:1071-82 (2007)
DOI:10.1016/j.molcel.2007.10.033
  Sequence
[hsa:55740]
LinkDB

KEGG   ORTHOLOGY: K23487
Entry
K23487                      KO                                     

Name
EVL
Definition
Ena/VASP-like protein
Pathway
ko04015  Rap1 signaling pathway
ko04361  Axon regeneration
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K23487  EVL; Ena/VASP-like protein
 09150 Organismal Systems
  09158 Development and regeneration
   04361 Axon regeneration
    K23487  EVL; Ena/VASP-like protein
Genes
HSA: 51466(EVL)
PTR: 746207(EVL)
PPS: 100979361(EVL)
GGO: 101143446(EVL)
PON: 100173130(EVL)
NLE: 100605928(EVL)
MCC: 706316(EVL)
MCF: 101866983(EVL)
CSAB: 103229687(EVL)
RRO: 104654458(EVL)
RBB: 108542288(EVL)
CJC: 100408931(EVL)
SBQ: 101028904(EVL)
MMU: 14026(Evl)
MCAL: 110306431(Evl)
MPAH: 110324494(Evl)
RNO: 79115(Evl)
MUN: 110551783(Evl)
CGE: 100771012(Evl)
NGI: 103727651(Evl)
HGL: 101706785(Evl)
CCAN: 109694356(Evl)
OCU: 100352730
TUP: 102483727(EVL)
CFA: 480433(EVL)
VVP: 112930234(EVL)
AML: 100470084(EVL)
UMR: 103673585(EVL)
UAH: 113267273(EVL)
ORO: 101366352(EVL)
ELK: 111148488
FCA: 101080297(EVL)
PTG: 102958141(EVL)
PPAD: 109274393(EVL)
AJU: 106972184(EVL)
BTA: 506201(EVL)
BOM: 102271054(EVL)
BIU: 109575436(EVL)
BBUB: 102407862(EVL)
CHX: 102178774(EVL)
OAS: 101118138(EVL)
SSC: 100513162(EVL)
CFR: 102514390(EVL)
CDK: 105095385(EVL)
BACU: 103011158(EVL)
LVE: 103091382(EVL)
OOR: 101281034(EVL)
DLE: 111176087(EVL)
PCAD: 102997020(EVL)
ECB: 100049905(EVL)
EPZ: 103564050(EVL)
EAI: 106839664(EVL)
MYB: 102251543(EVL)
MYD: 102755389(EVL)
MNA: 107541613(EVL)
HAI: 109381066(EVL)
DRO: 112311196(EVL)
PALE: 102883029(EVL)
RAY: 107497562(EVL)
MJV: 108400773(EVL)
LAV: 100674145(EVL)
TMU: 101349543
MDO: 100022783(EVL)
SHR: 100934916(EVL)
PCW: 110222411(EVL)
OAA: 100082156(EVL)
GGA: 423453(EVL)
MGP: 100546249(EVL)
CJO: 107315307(EVL)
NMEL: 110401291(EVL)
APLA: 101791929(EVL)
ACYG: 106033460(EVL)
TGU: 100228735(EVL)
LSR: 110481199(EVL)
SCAN: 103826878(EVL)
GFR: 102044780(EVL)
FAB: 101821401(EVL)
PHI: 102114591(EVL)
PMAJ: 107205857(EVL)
CCAE: 111945314
CCW: 104688790(EVL)
ETL: 114064451(EVL)
FPG: 101915607(EVL)
FCH: 102053004(EVL)
CLV: 102086301(EVL)
EGZ: 104124529(EVL)
NNI: 104014817(EVL)
ACUN: 113480549(EVL)
PADL: 103920401(EVL)
AAM: 106483084(EVL)
ASN: 102372004(EVL)
AMJ: 102572326(EVL)
PSS: 102451112(EVL)
CMY: 102940975(EVL)
CPIC: 101953573(EVL)
ACS: 100551821(evl)
PVT: 110070302(EVL)
PBI: 103058467(EVL)
PMUR: 107291275(EVL)
TSR: 106543354(EVL)
PMUA: 114587456(EVL)
GJA: 107121538(EVL)
XLA: 496406(evl.L) 779377(evl.S)
XTR: 100124792(evl)
NPR: 108801751(EVL)
DRE: 402929(evlb) 58003(evla)
BPEC: 110155421(evl) 110168284
SFM: 108941453(evl)
PKI: 111833683 111852421(evl)
LCM: 102359380(EVL)
CMK: 103175330(evl)
RTP: 109913157
CEL: CELE_Y50D4C.1(unc-34)
CBR: CBG17885(Cbr-unc-34)
BMY: Bm1_50615
PCAN: 112570206
CRG: 105320101
MYI: 110450472
LAK: 106169606
EGL: EGR_01485
EPA: 110252820
ADF: 107357919
AMIL: 114956728
PDAM: 113668354
SPIS: 111327470
 » show all
Reference
PMID:8861907
  Authors
Gertler FB, Niebuhr K, Reinhard M, Wehland J, Soriano P
  Title
Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics.
  Journal
Cell 87:227-39 (1996)
DOI:10.1016/s0092-8674(00)81341-0
  Sequence
[mmu:14026]
LinkDB

DBGET integrated database retrieval system