KEGG   ORTHOLOGY: K06278
Entry
K06278                      KO                                     

Name
CAV1
Definition
caveolin 1
Pathway
ko04144  Endocytosis
ko04510  Focal adhesion
ko05020  Prion disease
ko05100  Bacterial invasion of epithelial cells
ko05205  Proteoglycans in cancer
ko05416  Viral myocarditis
ko05418  Fluid shear stress and atherosclerosis
Disease
H00419  Congenital generalized lipodystrophy
H01621  Pulmonary arterial hypertension
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K06278  CAV1; caveolin 1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06278  CAV1; caveolin 1
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K06278  CAV1; caveolin 1
  09164 Neurodegenerative disease
   05020 Prion disease
    K06278  CAV1; caveolin 1
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K06278  CAV1; caveolin 1
   05416 Viral myocarditis
    K06278  CAV1; caveolin 1
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    K06278  CAV1; caveolin 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06278  CAV1; caveolin 1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K06278  CAV1; caveolin 1
Genes
HSA: 857(CAV1)
PTR: 463670(CAV1)
PPS: 100992465(CAV1)
GGO: 101125469(CAV1)
PON: 100137027(CAV1)
NLE: 100595808(CAV1)
MCC: 704449(CAV1)
MCF: 101865646(CAV1)
CSAB: 103226770(CAV1)
RRO: 104682636(CAV1)
RBB: 108528700(CAV1)
CJC: 100407940(CAV1)
SBQ: 101039198(CAV1)
MMU: 12389(Cav1)
MCAL: 110296656(Cav1)
MPAH: 110315910(Cav1)
RNO: 25404(Cav1)
MUN: 110552608(Cav1)
CGE: 100753021(Cav1)
NGI: 103737442(Cav1)
HGL: 101726366(Cav1)
CCAN: 109689878(Cav1)
OCU: 100008837(CAV1)
TUP: 102486553(CAV1)
CFA: 403980(CAV1)
VVP: 112929872(CAV1)
AML: 100480993(CAV1)
UMR: 103676584(CAV1)
UAH: 113263202(CAV1)
ORO: 101366038(CAV1)
ELK: 111151954
FCA: 493668(CAV1)
PTG: 102953130(CAV1)
PPAD: 109248391(CAV1)
AJU: 106970671(CAV1)
BTA: 281040(CAV1)
BOM: 102285349(CAV1)
BIU: 109557414(CAV1)
BBUB: 102392479(CAV1)
CHX: 100860749(CAV1)
OAS: 445468(CAV1)
SSC: 404693(CAV1)
CFR: 102503556(CAV1)
CDK: 105085320(CAV1)
BACU: 103001646(CAV1)
LVE: 103091453(CAV1)
OOR: 101280391(CAV1)
DLE: 111179315(CAV1)
PCAD: 102978243(CAV1)
ECB: 100055975(CAV1)
EPZ: 103561370(CAV1)
EAI: 106829272(CAV1)
MYB: 102263659(CAV1)
MYD: 102756043(CAV1)
MNA: 107528537(CAV1)
HAI: 109389343(CAV1)
DRO: 112300423(CAV1)
PALE: 102886570(CAV1)
RAY: 107497470(CAV1)
MJV: 108399323(CAV1)
LAV: 100655995(CAV1)
TMU: 101345849
MDO: 100011809(CAV1)
SHR: 100916741(CAV1)
PCW: 110202945(CAV1)
OAA: 100079536(CAV1)
GGA: 373996(CAV1)
MGP: 100545970(CAV1)
CJO: 107309151(CAV1)
NMEL: 110392605(CAV1)
APLA: 101801891(CAV1)
ACYG: 106042074(CAV1)
TGU: 100220361(CAV1)
LSR: 110477140(CAV1)
SCAN: 103813464(CAV1)
GFR: 102035118(CAV1)
FAB: 101805834(CAV1)
PHI: 102100055(CAV1)
PMAJ: 107205027(CAV1)
CCAE: 111937042(CAV1)
CCW: 104698449(CAV1)
ETL: 114062362(CAV1)
FPG: 101923838(CAV1)
FCH: 102045976(CAV1)
CLV: 102091371(CAV1)
EGZ: 104133410(CAV1)
NNI: 104013626(CAV1)
ACUN: 113491225(CAV1)
PADL: 103917009(CAV1)
AAM: 106488973(CAV1)
ASN: 102368943(CAV1)
AMJ: 102564658(CAV1)
PSS: 102446686(CAV1)
CMY: 102946208(CAV1)
CPIC: 101953863(CAV1)
ACS: 100561047(cav1)
PVT: 110077030(CAV1)
PBI: 103067393
PMUR: 107287882(CAV1)
TSR: 106557422(CAV1)
PMUA: 114605528(CAV1)
GJA: 107113790(CAV1)
XLA: 398392(cav1.S) 399006(cav1.L)
XTR: 548467(cav1)
NPR: 108788996(CAV1)
DRE: 323695(cav1)
IPU: 108269231(Caveolin-1)
PHYP: 113546657
AMEX: 103028370
EEE: 113584982
TRU: 100137154(cav1)
LCO: 104931752(cav1)
NCC: 104956274
MZE: 101466056(cav1)
ONL: 100709711(cav1)
OLA: 101162818
XMA: 102217707(cav1)
XCO: 114142844(cav1)
CVG: 107083221(cav1)
NFU: 107388349(cav1)
KMR: 108248208
ALIM: 106535805
AOCE: 111572792(cav1)
CSEM: 103379588(cav1)
POV: 109624615(cav1)
LCF: 108893991(cav1)
SDU: 111220536(cav1)
SLAL: 111672162(cav1)
HCQ: 109530890(cav1)
MALB: 109956467(cav1)
SALP: 111962723
ELS: 105018292(cav1)
LCM: 102365573(CAV1)
CMK: 103179354(cav1)
RTP: 109912146
CIN: 100177697
TUT: 107363760
CSCU: 111633968
PTEP: 107443757
CEL: CELE_T13F2.8(cav-1)
CBR: CBG15010(Cbr-cav-1)
BMY: Bm1_36280
TSP: Tsp_03271
NVE: 5504524
AQU: 109585694
 » show all
Reference
  Authors
Vargas L, Nore BF, Berglof A, Heinonen JE, Mattsson PT, Smith CI, Mohamed AJ
  Title
Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx.
  Journal
J Biol Chem 277:9351-7 (2002)
DOI:10.1074/jbc.M108537200
  Sequence
[hsa:857]
Reference
PMID:1360410
  Authors
Glenney JR Jr
  Title
The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles.
  Journal
FEBS Lett 314:45-8 (1992)
DOI:10.1016/0014-5793(92)81458-X
  Sequence
[hsa:857]
LinkDB

KEGG   ORTHOLOGY: K12958
Entry
K12958                      KO                                     

Name
CAV2
Definition
caveolin 2
Pathway
ko04144  Endocytosis
ko04510  Focal adhesion
ko05020  Prion disease
ko05100  Bacterial invasion of epithelial cells
ko05205  Proteoglycans in cancer
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12958  CAV2; caveolin 2
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12958  CAV2; caveolin 2
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K12958  CAV2; caveolin 2
  09164 Neurodegenerative disease
   05020 Prion disease
    K12958  CAV2; caveolin 2
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K12958  CAV2; caveolin 2
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    K12958  CAV2; caveolin 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12958  CAV2; caveolin 2
Membrane trafficking [BR:ko04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K12958  CAV2; caveolin 2
Genes
HSA: 858(CAV2)
PTR: 736452(CAV2)
PPS: 100992816(CAV2)
GGO: 101124237(CAV2)
PON: 100137028(CAV2)
NLE: 100596151(CAV2)
MCC: 706980(CAV2)
MCF: 102122005(CAV2)
CSAB: 103226769(CAV2)
RRO: 104682637(CAV2)
RBB: 108528701(CAV2)
CJC: 100414174(CAV2) 103790609
SBQ: 101039961(CAV2)
MMU: 12390(Cav2)
MCAL: 110296653(Cav2)
MPAH: 110315911(Cav2)
RNO: 363425(Cav2)
MUN: 110552609(Cav2)
CGE: 100751645(Cav2)
NGI: 103737451(Cav2)
HGL: 101696479(Cav2)
CCAN: 109689881(Cav2)
OCU: 100126563(CAV2)
TUP: 102486965(CAV2)
CFA: 475294(CAV2)
VVP: 112929900(CAV2)
AML: 100481243(CAV2)
UMR: 103676671(CAV2)
UAH: 113263196(CAV2)
ORO: 101366509(CAV2)
ELK: 111151976
FCA: 493667(CAV2)
PTG: 102952837(CAV2)
PPAD: 109248392(CAV2)
AJU: 106970672(CAV2)
BTA: 493642(CAV2)
BOM: 102284893(CAV2)
BIU: 109557415(CAV2)
BBUB: 102391932(CAV2)
CHX: 102176581(CAV2)
OAS: 100126571(CAV2)
SSC: 100125375(CAV2)
CFR: 102524490(CAV2)
CDK: 105085318(CAV2)
BACU: 103001094(CAV2)
LVE: 103068687(CAV2)
OOR: 101280988(CAV2)
DLE: 111179321(CAV2)
PCAD: 102977968(CAV2)
ECB: 100071136(CAV2)
EPZ: 103561371(CAV2)
EAI: 106829266(CAV2)
MYB: 102264168(CAV2)
MYD: 102756981(CAV2)
MNA: 107528527(CAV2)
HAI: 109389345(CAV2)
DRO: 112300182(CAV2)
PALE: 102887161(CAV2)
RAY: 107497469(CAV2)
MJV: 108399324(CAV2)
LAV: 100655716(CAV2)
TMU: 101347312
MDO: 100011724(CAV2)
SHR: 100916483(CAV2)
PCW: 110202942(CAV2)
OAA: 100091379 114814756(CAV2)
GGA: 417772(CAV2)
MGP: 104909643(CAV2)
CJO: 107309156(CAV2)
NMEL: 110392606(CAV2)
APLA: 101805307(CAV2)
ACYG: 106042050(CAV2)
TGU: 101234223(CAV2)
LSR: 110477138(CAV2)
SCAN: 103813681(CAV2)
GFR: 102040661(CAV2)
FAB: 101810092(CAV2)
PHI: 102100230(CAV2)
PMAJ: 107205109(CAV2)
CCAE: 111922633(CAV2)
CCW: 104698291(CAV2)
ETL: 114062359(CAV2)
FPG: 101912583(CAV2)
FCH: 102050239(CAV2)
EGZ: 104133418(CAV2)
NNI: 104013627(CAV2)
ACUN: 113491224(CAV2)
PADL: 103917010(CAV2)
AAM: 106488129(CAV2)
ASN: 102368692(CAV2)
AMJ: 102564889(CAV2)
PSS: 102447339(CAV2)
CMY: 102932255(CAV2)
CPIC: 101953479(CAV2)
ACS: 100560849(cav2) 100562999
PVT: 110077035(CAV2) 110078663
PMUR: 107284239 107287881(CAV2)
TSR: 106557421(CAV2)
PMUA: 114587875 114605517(CAV2)
GJA: 107113782(CAV2)
XTR: 100496423 548480(cav2)
NPR: 108784481 108788741(CAV2)
DRE: 100136849(zgc:172270) 415240(cav2) 791212(zgc:158296)
TRU: 100137153(cav2) 101069917
HCQ: 109530889(cav2) 109531487
CMK: 103176736 103179353(cav2)
CEL: CELE_C56A3.7(cav-2)
CBR: CBG06676(Cbr-cav-2)
MYI: 110465941
 » show all
Reference
  Authors
Kwon H, Jeong K, Hwang EM, Park JY, Hong SG, Choi WS, Pak Y
  Title
Caveolin-2 regulation of STAT3 transcriptional activation in response to insulin.
  Journal
Biochim Biophys Acta 1793:1325-33 (2009)
DOI:10.1016/j.bbamcr.2009.04.015
  Sequence
[rno:363425]
Reference
PMID:8552590
  Authors
Scherer PE, Okamoto T, Chun M, Nishimoto I, Lodish HF, Lisanti MP
  Title
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.
  Journal
Proc Natl Acad Sci U S A 93:131-5 (1996)
DOI:10.1073/pnas.93.1.131
  Sequence
[hsa:858]
LinkDB

KEGG   ORTHOLOGY: K12959
Entry
K12959                      KO                                     

Name
CAV3
Definition
caveolin 3
Pathway
ko04144  Endocytosis
ko04510  Focal adhesion
ko05020  Prion disease
ko05100  Bacterial invasion of epithelial cells
ko05205  Proteoglycans in cancer
ko05418  Fluid shear stress and atherosclerosis
Disease
H00567  Limb-girdle muscular dystrophy 1C
H00594  Distal myopathy
H00720  Long QT syndrome
H02179  Rippling muscle disease
H02181  Idiopathic hyperCKemia
H02182  Distal myopathy, Tateyama type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12959  CAV3; caveolin 3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12959  CAV3; caveolin 3
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K12959  CAV3; caveolin 3
  09164 Neurodegenerative disease
   05020 Prion disease
    K12959  CAV3; caveolin 3
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K12959  CAV3; caveolin 3
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    K12959  CAV3; caveolin 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12959  CAV3; caveolin 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K12959  CAV3; caveolin 3
Genes
HSA: 859(CAV3)
PTR: 738786(CAV3)
PPS: 100987875(CAV3)
GGO: 101128051(CAV3)
PON: 100440174(CAV3)
NLE: 100591755(CAV3)
MCC: 702163(CAV3)
MCF: 102133753(CAV3)
CSAB: 103227961(CAV3)
RRO: 104667478(CAV3)
RBB: 108530950(CAV3)
CJC: 100405927(CAV3)
SBQ: 101051489(CAV3)
MMU: 12391(Cav3)
MCAL: 110296907(Cav3)
MPAH: 110317056(Cav3)
RNO: 29161(Cav3)
MUN: 110548321(Cav3)
CGE: 100773488(Cav3)
NGI: 103751406(Cav3)
HGL: 101716522(Cav3)
CCAN: 109697912(Cav3)
OCU: 100342999(CAV3)
TUP: 102481829(CAV3)
CFA: 484671(CAV3)
VVP: 112933680(CAV3)
AML: 100473119(CAV3)
UMR: 103669585(CAV3)
UAH: 113256564(CAV3)
ORO: 101367308(CAV3)
ELK: 111144224
FCA: 101081453(CAV3)
PTG: 102952406(CAV3)
PPAD: 109254405(CAV3)
AJU: 106972343(CAV3)
BTA: 615310(CAV3)
BOM: 102272328(CAV3)
BIU: 109576337(CAV3)
BBUB: 102402971(CAV3)
CHX: 102189719(CAV3)
OAS: 101107228(CAV3)
SSC: 641358(CAV3)
CFR: 102509085(CAV3)
CDK: 105093147(CAV3)
BACU: 103014158(CAV3)
LVE: 103082615(CAV3)
OOR: 101285456(CAV3)
DLE: 111169961(CAV3)
PCAD: 102991626
ECB: 100058881(CAV3)
EPZ: 103559029(CAV3)
EAI: 106841765(CAV3)
MYB: 102239844(CAV3)
MYD: 102754131(CAV3)
MNA: 107534781(CAV3)
HAI: 109387266(CAV3)
DRO: 112301291(CAV3)
PALE: 102879431(CAV3)
RAY: 107504953(CAV3)
MJV: 108401772(CAV3)
LAV: 100663316(CAV3)
TMU: 101344988
MDO: 100023521(CAV3)
SHR: 100922621(CAV3)
PCW: 110199079(CAV3)
OAA: 114806542(CAV3)
GGA: 378796(CAV3)
MGP: 100543378(CAV3)
CJO: 107320020(CAV3)
NMEL: 110404959(CAV3)
APLA: 101792227(CAV3)
ACYG: 106036683(CAV3)
TGU: 100230016(CAV3)
LSR: 110480413(CAV3)
SCAN: 103824133(CAV3)
GFR: 102031628(CAV3)
FAB: 101818067(CAV3)
PHI: 102107046(CAV3)
PMAJ: 107210086(CAV3)
CCAE: 111934858(CAV3)
CCW: 104683396(CAV3)
ETL: 114071677(CAV3)
FPG: 101917303(CAV3)
FCH: 102051891(CAV3)
CLV: 102098428(CAV3)
EGZ: 104121785(CAV3)
NNI: 104016951(CAV3)
ACUN: 113485026(CAV3)
PADL: 103913591(CAV3)
AAM: 106494828(CAV3)
ASN: 102375612(CAV3)
AMJ: 102560790(CAV3)
PSS: 102443696(CAV3)
CMY: 102937725(CAV3)
CPIC: 101940800(CAV3)
ACS: 100552705
PVT: 110078681
PBI: 103065936
PMUR: 107284237
TSR: 106554303
PMUA: 114587521
GJA: 107107655
XLA: 108698292 108714608 108714631(cav3.1.L) 379866(cav3.2.S)
XTR: 100124941(cav3.2) 100125124(cav3.1)
DRE: 449679(cav3)
IPU: 100528411(cav3)
PHYP: 113532600(cav3)
AMEX: 103034163(cav3)
EEE: 113569652(cav3)
TRU: 101073024(cav3) 115246796
LCO: 104920518 109139553(cav3)
NCC: 104966112(cav3)
MZE: 101484108(cav3)
ONL: 100693678
OLA: 101171655(cav3)
XMA: 102227510(cav3)
XCO: 114136035(cav3)
PRET: 103465216(cav3)
CVG: 107093348
NFU: 107385739(cav3)
KMR: 108235734(cav3)
ALIM: 106517985(cav3)
AOCE: 111575516(cav3)
CSEM: 103385740 103385901(cav3)
POV: 109628921(cav3)
LCF: 108886448(cav3)
SDU: 111222144(cav3) 111222817
HCQ: 109522675
BPEC: 110168681(cav3)
MALB: 109964419(cav3)
ELS: 105017029(cav3) 105026474
SFM: 108923405(cav3) 108936949
LCM: 102354564 102362893(CAV3)
CMK: 103176735(cav3)
RTP: 109918881
AME: 408310
BIM: 105681799
BTER: 105666290
CCAL: 108624100
OBB: 114872453
SOC: 105194358
MPHA: 105828986
AEC: 105151851
ACEP: 105623631
PBAR: 105426480
VEM: 105567484
HST: 105183579
DQU: 106746609
CFO: 105252499
LHU: 105676733
PGC: 109856472
OBO: 105288182
PCF: 106789272
NVI: 100113488
CSOL: 105365070
MDL: 103574490
ATD: 109608791
NVL: 108559981
BMOR: 101746801
BMAN: 114246049
PMAC: 106713388
PRAP: 110994991
HAW: 110383123
TNL: 113500964
ZNE: 110828891
FCD: 110862084
PVM: 113809670
CSCU: 111622705
PTEP: 107438457
OBI: 106879285
NVE: 5513598
ADF: 107351074
AMIL: 114957935
PHO: PH1330(PH1330)
 » show all
Reference
  Authors
Cai C, Weisleder N, Ko JK, Komazaki S, Sunada Y, Nishi M, Takeshima H, Ma J
  Title
Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin.
  Journal
J Biol Chem 284:15894-902 (2009)
DOI:10.1074/jbc.M109.009589
  Sequence
[mmu:12391]
Reference
PMID:9545514
  Authors
Biederer C, Ries S, Drobnik W, Schmitz G
  Title
Molecular cloning of human caveolin 3.
  Journal
Biochim Biophys Acta 1406:5-9 (1998)
DOI:10.1016/S0925-4439(97)00095-1
  Sequence
[hsa:859]
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