KEGG   ORTHOLOGY: K06450
Entry
K06450                      KO                                     

Name
CD3D
Definition
T-cell surface glycoprotein CD3 delta chain
Pathway
ko04640  Hematopoietic cell lineage
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko05142  Chagas disease
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05340  Primary immunodeficiency
Disease
H00091  T-B+Severe combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   04660 T cell receptor signaling pathway
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   04658 Th1 and Th2 cell differentiation
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   04659 Th17 cell differentiation
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
  09163 Immune disease
   05340 Primary immunodeficiency
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   05170 Human immunodeficiency virus 1 infection
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   05162 Measles
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
   05169 Epstein-Barr virus infection
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
CD molecules [BR:ko04090]
 Proteins
  K06450  CD3d; CD3D antigen, delta polypeptide (TiT3 complex)
Genes
HSA: 915(CD3D)
PTR: 451584(CD3D)
PPS: 100979946(CD3D)
GGO: 101150395(CD3D)
PON: 100440740(CD3D)
NLE: 100603907(CD3D)
MCC: 699582(CD3D)
MCF: 102133701(CD3D)
CSAB: 103248585(CD3D)
RRO: 104665574(CD3D)
RBB: 108536385(CD3D)
CJC: 100404313(CD3D)
SBQ: 101029738(CD3D)
MMU: 12500(Cd3d)
MCAL: 110302262(Cd3d)  
MPAH: 110328514(Cd3d)
RNO: 25710(Cd3d)
MUN: 110549118(Cd3d)
CGE: 100756906(Cd3d)
NGI: 103748303(Cd3d)
HGL: 101712534(Cd3d)
CCAN: 109699106(Cd3d)
OCU: 100356153(CD3D)
TUP: 102498607(CD3D)
CFA: 479419(CD3D)
VVP: 112920226(CD3D)  
AML: 100484718(CD3D)
UMR: 103662337(CD3D)
UAH: 113260002(CD3D)
ORO: 101385969(CD3D)
ELK: 111153823
FCA: 101083107(CD3D)
PTG: 102969057(CD3D)  
PPAD: 109278564(CD3D)
AJU: 106966153(CD3D)
BTA: 281053(CD3D)
BOM: 102272573(CD3D)
BIU: 109569960(CD3D)
BBUB: 102390133(CD3D)
CHX: 102191154(CD3D)
OAS: 443397(CD3D)
SSC: 396661(CD3D)
CFR: 102505672(CD3D)
CDK: 105090171(CD3D)
BACU: 103003761(CD3D)
LVE: 103069825(CD3D)
OOR: 101279567(CD3D)
DLE: 111166923(CD3D)
PCAD: 102979567(CD3D)
ECB: 100062931(CD3D)
EPZ: 103546675(CD3D)
EAI: 106840277(CD3D)
MYB: 102240563(CD3D)
MYD: 102753304(CD3D)
MNA: 107530792(CD3D)
HAI: 109385283(CD3D)
DRO: 112314228(CD3D)
PALE: 102894486(CD3D)  
RAY: 107516062(CD3D)
MJV: 108385099(CD3D)
LAV: 100661471(CD3D)
TMU: 101353008
MDO: 100031472(CD3D)
SHR: 100925080
PCW: 110207189(CD3D)
OAA: 100090811
GGA: 396518(CD3D)
MGP: 100543119
CJO: 107324150
APLA: 101792606
ACYG: 106039849(CD3D)
TGU: 100222416
LSR: 110470410
SCAN: 103822979
GFR: 102042200
FAB: 101820502
PHI: 102106764(CD3D)
PMAJ: 107214324
CCAE: 111939276
CCW: 104692179
FPG: 101916542(CD3D)
FCH: 102052093(CD3D)
CLV: 102092403(CD3D)
EGZ: 104124562
NNI: 104019039(CD3D)
ACUN: 113488514
PADL: 103921538(CD3D)
AAM: 106491545(CD3D)
ASN: 102382203(CD3D)
AMJ: 102572479(CD3D)
CPIC: 101940477
ACS: 103281391
GJA: 107112603(CD3G)
SRX: 107710511
SGH: 107557647
IPU: 100305122 108278320(cd3g)
TRU: 654302(cd3g/d)
MZE: 101473769(cd3g)
XMA: 111611912
XCO: 114133423
ALIM: 106521072
CSEM: 103377691
SDU: 111232852
SALP: 111957658
CMK: 103191344(cd3g)  
RTP: 109926251
 » show all
Reference
PMID:3488209
  Authors
Tunnacliffe A, Sims JE, Rabbitts TH
  Title
T3 delta pre-mRNA is transcribed from a non-TATA promoter and is alternatively spliced in human T cells.
  Journal
EMBO J 5:1245-52 (1986)
DOI:10.1002/j.1460-2075.1986.tb04353.x
  Sequence
[hsa:915]
Reference
  Authors
de Saint Basile G, Geissmann F, Flori E, Uring-Lambert B, Soudais C, Cavazzana-Calvo M, Durandy A, Jabado N, Fischer A, Le Deist F
  Title
Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3.
  Journal
J Clin Invest 114:1512-7 (2004)
DOI:10.1172/JCI22588
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