KEGG   ORTHOLOGY: K06472
Entry
K06472                      KO                                     

Name
FCGR2A, CD32
Definition
low affinity immunoglobulin gamma Fc receptor II-a
Pathway
ko04145  Phagosome
ko04380  Osteoclast differentiation
ko04611  Platelet activation
ko04666  Fc gamma R-mediated phagocytosis
ko05130  Pathogenic Escherichia coli infection
ko05135  Yersinia infection
ko05140  Leishmaniasis
ko05150  Staphylococcus aureus infection
ko05152  Tuberculosis
ko05322  Systemic lupus erythematosus
Disease
H00080  Systemic lupus erythematosus
H01360  Allergic rhinitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   04666 Fc gamma R-mediated phagocytosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05135 Yersinia infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05150 Staphylococcus aureus infection
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
   05152 Tuberculosis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Fc receptors
    K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
CD molecules [BR:ko04090]
 Proteins
  K06472  CD32a, FCGR2A; Fc fragment of IgG, low affinity IIa, receptor for (CD32)
Other DBs
GO: 0019770
Genes
HSA: 2212(FCGR2A)
PTR: 107973075 450194(FCGR2A)
PPS: 100991644(FCGR2A)
GGO: 101130688(FCGR2A)
PON: 100455333(FCGR2A)
NLE: 101176530(FCGR2A)
MCC: 719996(FCGR2A)
MCF: 102143568(FCGR2A)
CSAB: 103223676(FCGR2A)
RRO: 104669518(FCGR2A)
RBB: 108542586(FCGR2A)
CJC: 100387574(FCGR2A)
SBQ: 101040113(FCGR2A)
MCAL: 110288995
MPAH: 110321588
RNO: 498276
MUN: 110554429(Fcgr2a)
CGE: 103161891
NGI: 103746769(Fcgr2a)
HGL: 101700630(Fcgr2a)
CCAN: 109693506(Fcgr2a)
OCU: 100338413(FCGR2A)
BOM: 102274112
BIU: 109578180
OAS: 101106730
PCAD: 112062432
EPZ: 103540857 103540858(FCGR2A)
EAI: 106831113 106831115(FCGR2A)
MYB: 102263991
PALE: 102879478
RAY: 107502475
LAV: 104846329(FCGR2A)
TMU: 101350744
SANH: 107686749
TRU: 101072820
OLA: 105356322
XMA: 111611255
KMR: 112449806
SDU: 111239865
BPEC: 110172767
SASA: 106571983
ELS: 109615278
 » show all
Reference
PMID:2824655
  Authors
Stuart SG, Trounstine ML, Vaux DJ, Koch T, Martens CL, Mellman I, Moore KW
  Title
Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).
  Journal
J Exp Med 166:1668-84 (1987)
DOI:10.1084/jem.166.6.1668
  Sequence
[hsa:2212]
Reference
  Authors
Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD
  Title
Structural recognition and functional activation of FcgammaR by innate pentraxins.
  Journal
Nature 456:989-92 (2008)
DOI:10.1038/nature07468
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