KEGG   ORTHOLOGY: K06679
Entry
K06679                      KO                                     

Name
MAD1
Definition
mitotic spindle assembly checkpoint protein MAD1
Pathway
ko04110  Cell cycle
ko04111  Cell cycle - yeast
ko04113  Meiosis - yeast
ko04114  Oocyte meiosis
ko04914  Progesterone-mediated oocyte maturation
ko05166  Human T-cell leukemia virus 1 infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
   04111 Cell cycle - yeast
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
   04113 Meiosis - yeast
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
   04114 Oocyte meiosis
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
Genes
HSA: 8379(MAD1L1)
PTR: 463223(MAD1L1)
PPS: 100974341(MAD1L1)
GGO: 101144578(MAD1L1)
PON: 100454918(MAD1L1)
NLE: 100597403(MAD1L1)
MCC: 712947(MAD1L1)
MCF: 102147242(MAD1L1)
CSAB: 103246871(MAD1L1)
RRO: 104664955(MAD1L1)
RBB: 108543747(MAD1L1)
CJC: 100403983(MAD1L1)
SBQ: 101035986(MAD1L1)
MMU: 17120(Mad1l1)
MCAL: 110294349(Mad1l1)
MPAH: 110312757(Mad1l1)
RNO: 680006(Mad1l1)
MUN: 110554722(Mad1l1) 110557522
CGE: 100689352(Mad1l1)
NGI: 103748681(Mad1l1)
HGL: 101711604(Mad1l1)
OCU: 100348625(MAD1L1) 103347105
TUP: 102475523(MAD1L1)
CFA: 609673(MAD1L1)
VVP: 112929302(MAD1L1)
AML: 105234697(MAD1L1)
UMR: 103670064(MAD1L1)
UAH: 113247728(MAD1L1)
ORO: 101367895(MAD1L1)
ELK: 111145738
FCA: 101086024(MAD1L1)
PPAD: 109251121(MAD1L1)
AJU: 106984516(MAD1L1)
BTA: 517837(MAD1L1)
BOM: 102287083(MAD1L1)
BIU: 109578386(MAD1L1)
BBUB: 102413631(MAD1L1)
CHX: 102170846(MAD1L1)
OAS: 105605963(MAD1L1)
SSC: 102157652(MAD1L1)
CFR: 106729464(MAD1L1)
CDK: 105104789(MAD1L1)
BACU: 102999245(MAD1L1)
LVE: 103072712 103091432(MAD1L1)
OOR: 101283736(MAD1L1)
DLE: 111169381(MAD1L1)
PCAD: 102986764(MAD1L1)
ECB: 100058904(MAD1L1)
EPZ: 103551751(MAD1L1)
EAI: 106834769(MAD1L1)
MYB: 102262354(MAD1L1)
MYD: 102766642(MAD1L1)
MNA: 107537043(MAD1L1)
HAI: 109380140(MAD1L1)
DRO: 112319495(MAD1L1)
PALE: 102891468(MAD1L1)
RAY: 107497366(MAD1L1)
MJV: 108403423(MAD1L1)
LAV: 100675028(MAD1L1)
TMU: 101341859
MDO: 100029239(MAD1L1)
SHR: 100933550(MAD1L1)
PCW: 110200097(MAD1L1)
OAA: 100083012(MAD1L1)
GGA: 427658(MAD1L1)
MGP: 100548507(MAD1L1)
CJO: 107320743(MAD1L1)
NMEL: 110406085(MAD1L1)
APLA: 101795780(MAD1L1)
ACYG: 106033542(MAD1L1)
TGU: 100231865(MAD1L1)
LSR: 110475492(MAD1L1)
SCAN: 103817636(MAD1L1)
GFR: 102043620(MAD1L1)
FAB: 101818325(MAD1L1)
PHI: 102103130(MAD1L1)
PMAJ: 107211338(MAD1L1)
CCAE: 111936084(MAD1L1)
CCW: 104684819(MAD1L1)
ETL: 114054777(MAD1L1)
FPG: 101924864(MAD1L1)
FCH: 102057977(MAD1L1)
CLV: 102089676(MAD1L1)
EGZ: 104132612(MAD1L1)
NNI: 104015084(MAD1L1)
ACUN: 113485781(MAD1L1)
PADL: 103913527(MAD1L1)
AAM: 106499960(MAD1L1)
ASN: 102373658 102382343(MAD1L1)
AMJ: 102570055(MAD1L1)
PSS: 102462064(MAD1L1)
CMY: 102933206(MAD1L1)
CPIC: 101931462(MAD1L1)
ACS: 100552348(mad1l1)
PVT: 110084705(MAD1L1)
PMUR: 107290612(MAD1L1)
PMUA: 114584324(MAD1L1)
GJA: 107119572(MAD1L1)
XLA: 394307(mad1l1.L)
XTR: 448774(mad1l1)
NPR: 108790265(MAD1L1)
DRE: 393886(mad1l1)
CCAR: 109078424(mad1l1) 109083105
IPU: 108259051(mad1l1)
PHYP: 113535786(mad1l1)
AMEX: 103029264(mad1l1)
EEE: 113574943(mad1l1)
TRU: 101073394(mad1l1)
LCO: 104921158(mad1l1)
NCC: 104942857
MZE: 101470681(mad1l1)
ONL: 100697468(mad1l1)
OLA: 101175462(mad1l1)
XMA: 102233788(mad1l1)
XCO: 114145249(mad1l1)
PRET: 103457167(mad1l1)
CVG: 107088926(mad1l1)
NFU: 107389985(mad1l1)
KMR: 108242568(mad1l1)
ALIM: 106522719(mad1l1)
AOCE: 111566261(mad1l1)
CSEM: 103383455(mad1l1)
POV: 109639600(mad1l1)
LCF: 108886079 108901178(mad1l1)
SDU: 111216628(mad1l1)
SLAL: 111672999(mad1l1)
HCQ: 109511264(mad1l1)
BPEC: 110165233(mad1l1) 110172801
MALB: 109973311(mad1l1)
ELS: 105029858(mad1l1)
SFM: 108927531(mad1l1)
PKI: 111845484(mad1l1)
LCM: 102350418(MAD1L1)
CMK: 103186608(mad1l1)
RTP: 109930089(mad1l1)
BFO: 118429566
CIN: 100176070
SPU: 591426
APLC: 110976189
SKO: 102804614
DME: Dmel_CG2072(Mad1)
DER: 6540839
DSE: 6608334
DSI: Dsimw501_GD10086(Dsim_GD10086)
DAN: 6495931
DSR: 110177078
DPE: 6592673
DWI: 6640924
DAZ: 108615960
DNV: 108653076
DHE: 111604190
DVI: 6625709
MDE: 101895186
LCQ: 111675908
AAG: 5564411
AME: 724819
BIM: 100740877
BTER: 100645992
CCAL: 108632849
OBB: 114876868
SOC: 105207768
MPHA: 105834142
AEC: 105147145
ACEP: 105619284
PBAR: 105428049
VEM: 105570557
HST: 105190037
DQU: 106749602
CFO: 105252823
LHU: 105678216
PGC: 109857601
OBO: 105275677
PCF: 106793055
NVI: 100121045
CSOL: 105365526
MDL: 103580733
TCA: 656951
DPA: 109546667
NVL: 108566132
BMOR: 101746684
BMAN: 114243813
PMAC: 106711190
PRAP: 110991653
HAW: 110370535
TNL: 113504159
PXY: 105386038
API: 100160053
AGS: 114131844
RMD: 113551923
BTAB: 109031264
CLEC: 106663189
ZNE: 110836044
FCD: 110851311
PVM: 113820082
TUT: 107365178
DPTE: 113798534
CSCU: 111639148
PTEP: 107450844
BMY: Bm1_55635
PCAN: 112556420
CRG: 105329118
MYI: 110448590
SHX: MS3_05923
ADF: 107341588
AMIL: 114957616
PDAM: 113674204
SPIS: 111328280
HMG: 100215536
AQU: 109582179
ATH: AT5G49880(MAD1)
ALY: 9300095
CRB: 17874943
BRP: 103843885
BOE: 106319457
RSZ: 108828744
THJ: 104806651
CPAP: 110807388
CIT: 102619176
TCC: 18595210
GRA: 105772845
GAB: 108473556
DZI: 111278877
EGR: 104420029
VRA: 106769068
VAR: 108320215
VUN: 114175118
CCAJ: 109811373
CAM: 101495887
LJA: Lj4g3v0002130.1(Lj4g3v0002130.1) Lj4g3v0002130.2(Lj4g3v0002130.2)
ADU: 107465569
AIP: 107635826
LANG: 109352659
FVE: 101311286
RCN: 112179868
PPER: 18788348
PMUM: 103318955
PAVI: 110765748
PXB: 103946406
CSV: 101211260
CMO: 103499375
MCHA: 111022291
CMAX: 111492363
CMOS: 111439783
CPEP: 111792885
RCU: 8262563
JCU: 105629727
HBR: 110634728
JRE: 108988937
VVI: 100262667
SLY: 101256714
SPEN: 107006928
SOT: 102604068
CANN: 107839828
NSY: 104238547
NTO: 104117666
NAU: 109211160
INI: 109165276
SIND: 105169055
HAN: 110885611
LSV: 111878018
CCAV: 112516887
DCR: 108205176
BVG: 104897020
SOE: 110803577
NNU: 104593948
OSA: 4325085
DOSA: Os01t0877300-01(Os01g0877300)
OBR: 102715806
BDI: 100840306
ATS: 109752914(LOC109752914)
ZMA: 100285392(pco088261)
PDA: 103716630
EGU: 105036216
MUS: 103994283
DCT: 110110834
PEQ: 110037667
AOF: 109851213
ATR: 18427784
PPP: 112294880
APRO: F751_2940
SCE: YGL086W(MAD1)
KMX: KLMA_60359(MAD1)
NCS: NCAS_0D03670(NCAS0D03670)
NDI: NDAI_0I01220(NDAI0I01220)
TPF: TPHA_0J02260(TPHA0J02260)
TBL: TBLA_0B05160(TBLA0B05160)
TDL: TDEL_0G01570(TDEL0G01570)
KAF: KAFR_0C02150(KAFR0C02150)
PIC: PICST_53034(MAD1)
CAL: CAALFM_C112660WA(CaO19.6357)
NCR: NCU04428
NTE: NEUTE1DRAFT121192(NEUTE1DRAFT_121192)
MGR: MGG_04908
SSCK: SPSK_03055
MAW: MAC_00255
MAJ: MAA_08191
CMT: CCM_08765
BFU: BCIN_15g05340(Bcmad1)
MBE: MBM_01602
ANI: AN0696.2
ANG: ANI_1_944074(An08g06660)
ABE: ARB_07734
TVE: TRV_00479
PTE: PTT_16480
SPO: SPBC3D6.04c(mad1)
CNE: CNJ02500
CNB: CNBJ0960
TASA: A1Q1_07186
ABP: AGABI1DRAFT109561(AGABI1DRAFT_109561)
ABV: AGABI2DRAFT188863(AGABI2DRAFT_188863)
MGL: MGL_3198
MRT: MRET_2169
DDI: DDB_G0287755(mad1)
DFA: DFA_10664(mad1)
SPAR: SPRG_06144
 » show all
Reference
  Authors
Kim IG, Rhee DK, Jeong JW, Kim SC, Won M, Lee J, Song KW, Kim HB
  Title
Mad1p, a component of the spindle assembly checkpoint in fission yeast, suppresses a novel septation-defective mutant, sun1, in a cell-division cycle.
  Journal
FEMS Microbiol Lett 227:183-8 (2003)
DOI:10.1016/S0378-1097(03)00607-4
  Sequence
Reference
PMID:7593191
  Authors
Hardwick KG, Murray AW
  Title
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast.
  Journal
J Cell Biol 131:709-20 (1995)
DOI:10.1083/jcb.131.3.709
  Sequence
[sce:YGL086W]
Reference
  Authors
Sun SC, Kim NH
  Title
Spindle assembly checkpoint and its regulators in meiosis.
  Journal
Hum Reprod Update 18:60-72 (2012)
DOI:10.1093/humupd/dmr044
Reference
  Authors
Kruse T, Larsen MS, Sedgwick GG, Sigurdsson JO, Streicher W, Olsen JV, Nilsson J
  Title
A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment.
  Journal
EMBO Rep 15:282-90 (2014)
DOI:10.1002/embr.201338101
  Sequence
[hsa:8379]
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