KEGG   ORTHOLOGY: K06863
Entry
K06863                      KO                                     

Name
purP
Definition
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
Pathway
ko00230  Purine metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.23  formate---phosphoribosylaminoimidazolecarboxamide ligase
     K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
Other DBs
RN: R06975
COG: COG1759
Genes
PRF: PeribacterA2_0725 PeribacterA2_0726
MJA: MJ_0136
MFE: Mefer_0308
MVU: Metvu_0168
MFS: MFS40622_1004
MIF: Metin_0767
MJH: JH146_0737
MIG: Metig_0553
MMP: MMP1373
MMQ: MmarC5_0205
MMD: GYY_07695(purP)
MMAK: MMKA1_15970(purP)
MMAO: MMOS7_14780(purP)
MMAD: MMJJ_14660
MAE: Maeo_1327
MVO: Mvol_0265
METF: CFE53_06120(purP)
MTH: MTH_1201
MMG: MTBMA_c15790(purP)
METC: MTCT_1094
MWO: MWSIV6_1594(purP)
METE: tca_01158
MST: Msp_0240
METB: AW729_05985(purP)
MRU: mru_0595(purP)
MSI: Msm_0506
MEB: Abm4_1385(purP)
MMIL: sm9_0511(purP)
MEYE: TL18_02305(purP)
MOL: YLM1_0256
METH: MBMB1_0083(purP)
MFC: BRM9_0147(purP)
MFI: DSM1535_1470(purP)
MCUB: MCBB_2033(purP)
MSUB: BK009_10205(purP)
METN: BK008_05830(purP)
METT: CIT01_03875(purP)
METO: CIT02_06600(purP)
MFV: Mfer_0393
MKA: MK0588
MEAR: Mpt1_c09180(purP1) Mpt1_c13110(purP2)
PFI: PFC_01190 PFC_06820(purP)
PHO: PH0324(PH0324) PH1348(PH1348)
THE: GQS_02000(purP) GQS_05740(purP) GQS_05765
MBU: Mbur_1029(purP) Mbur_1626(purP)
MPY: Mpsy_0967(purP) Mpsy_1916
MPD: MCP_2462(purP-1) MCP_2481(purP-2) MCP_2482(purP-3)
MEZ: Mtc_2399(purP)
RCI: RCIX2374(purP)
SMR: Smar_1525
STO: STK_02890(purP) STK_02900(purP)
NCT: NMSP_0725(purP_1) NMSP_0856(purP_2)
NGA: Ngar_c02760(purP1) Ngar_c27450(purP2)
NVN: NVIE_014230(purP1) NVIE_015540(purP2)
NFN: NFRAN_0263(purP) NFRAN_1004(purP)
NCV: NCAV_0743(purP) NCAV_1281(purP)
NDV: NDEV_1117(purP) NDEV_1244(purP)
BARB: AOA66_0604(purP)
 » show all
Reference
  Authors
Ownby K, Xu H, White RH
  Title
A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis.
  Journal
J Biol Chem 280:10881-7 (2005)
DOI:10.1074/jbc.M413937200
  Sequence
[mja:MJ_0136]
Reference
  Authors
Zhang Y, White RH, Ealick SE
  Title
Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
  Journal
Biochemistry 47:205-17 (2008)
DOI:10.1021/bi701406g
  Sequence
[mja:MJ_0136] [pfu:PF1517]
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