KEGG   ORTHOLOGY: K07203
Entry
K07203                      KO                                     

Name
MTOR, FRAP, TOR
Definition
serine/threonine-protein kinase mTOR [EC:2.7.11.1]
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map04012  ErbB signaling pathway
map04066  HIF-1 signaling pathway
map04072  Phospholipase D signaling pathway
map04113  Meiosis - yeast
map04136  Autophagy - other
map04138  Autophagy - yeast
map04139  Mitophagy - yeast
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04211  Longevity regulating pathway
map04212  Longevity regulating pathway - worm
map04213  Longevity regulating pathway - multiple species
map04218  Cellular senescence
map04361  Axon regeneration
map04371  Apelin signaling pathway
map04613  Neutrophil extracellular trap formation
map04630  JAK-STAT signaling pathway
map04659  Th17 cell differentiation
map04714  Thermogenesis
map04910  Insulin signaling pathway
map04919  Thyroid hormone signaling pathway
map04920  Adipocytokine signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04935  Growth hormone synthesis, secretion and action
map05010  Alzheimer disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05163  Human cytomegalovirus infection
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05210  Colorectal cancer
map05212  Pancreatic cancer
map05214  Glioma
map05215  Prostate cancer
map05221  Acute myeloid leukemia
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05415  Diabetic cardiomyopathy
Disease
H01928  Smith-Kingsmore syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04371 Apelin signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04630 JAK-STAT signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04066 HIF-1 signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04072 Phospholipase D signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04151 PI3K-Akt signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04152 AMPK signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04150 mTOR signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04138 Autophagy - yeast
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04136 Autophagy - other
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04139 Mitophagy - yeast
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09143 Cell growth and death
   04113 Meiosis - yeast
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04218 Cellular senescence
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04659 Th17 cell differentiation
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04920 Adipocytokine signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04935 Growth hormone synthesis, secretion and action
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04919 Thyroid hormone signaling pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09158 Development and regeneration
   04361 Axon regeneration
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09149 Aging
   04211 Longevity regulating pathway
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04212 Longevity regulating pathway - worm
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04213 Longevity regulating pathway - multiple species
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09159 Environmental adaptation
   04714 Thermogenesis
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05206 MicroRNAs in cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05205 Proteoglycans in cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05207 Chemical carcinogenesis - receptor activation
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05230 Central carbon metabolism in cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05231 Choline metabolism in cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09162 Cancer: specific types
   05210 Colorectal cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05212 Pancreatic cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05225 Hepatocellular carcinoma
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05226 Gastric cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05214 Glioma
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05221 Acute myeloid leukemia
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05215 Prostate cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05224 Breast cancer
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05168 Herpes simplex virus 1 infection
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05163 Human cytomegalovirus infection
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05165 Human papillomavirus infection
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05014 Amyotrophic lateral sclerosis
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05016 Huntington disease
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05017 Spinocerebellar ataxia
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   05022 Pathways of neurodegeneration - multiple diseases
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   04931 Insulin resistance
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
   01522 Endocrine resistance
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  PIKK family [OT]
   K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR
Other DBs
COG: COG5032
Genes
HSA: 2475(MTOR)
PTR: 457945(MTOR)
PPS: 100980204(MTOR)
GGO: 101138990(MTOR)
PON: 100456786(MTOR)
NLE: 100594291(MTOR)
MCC: 106992736(MTOR)
MCF: 102128371(MTOR)
CSAB: 103225615(MTOR)
CATY: 105580870(MTOR)
PANU: 101015041(MTOR)
RRO: 104654362(MTOR)
RBB: 108539366(MTOR)
TFN: 117093322(MTOR)
PTEH: 111526309(MTOR)
CJC: 100406608(MTOR)
SBQ: 101047083(MTOR)
MMUR: 105886039(MTOR)
MMU: 56717(Mtor)
MCAL: 110292680(Mtor)
MPAH: 110323363(Mtor)
RNO: 56718(Mtor)
MCOC: 116097015(Mtor)
MUN: 110548161(Mtor)
CGE: 100755421(Mtor)
PLEU: 114709670(Mtor)
NGI: 103732897(Mtor)
HGL: 101725626(Mtor)
CCAN: 109689653 109689656(Mtor)
OCU: 100356164(MTOR)
TUP: 102485262(MTOR)
CFA: 478232(MTOR)
VVP: 112929738(MTOR)
VLG: 121496713(MTOR)
AML: 100471122(MTOR)
UMR: 103666660(MTOR)
UAH: 113270510(MTOR)
ORO: 101363844(MTOR)
ELK: 111154883
MPUF: 101676245(MTOR)
EJU: 114213180(MTOR)
MLX: 118020008(MTOR)
FCA: 101098152(MTOR)
PTG: 102967196(MTOR)
PPAD: 109274103(MTOR)
AJU: 106984907(MTOR)
HHV: 120233604(MTOR)
BTA: 100139219(MTOR)
BOM: 102281727(MTOR)
BIU: 109570401(MTOR)
BBUB: 102407977(MTOR)
CHX: 100860902(MTOR)
OAS: 100271659(MTOR)
ODA: 120880214(MTOR)
SSC: 100127359(MTOR)
CFR: 102510836(MTOR)
CDK: 105107024(MTOR)
BACU: 103004460(MTOR)
LVE: 103083889(MTOR)
OOR: 101284249(MTOR)
DLE: 111187265(MTOR)
PCAD: 102991493(MTOR)
ECB: 100051341(MTOR)
EPZ: 103552237(MTOR)
EAI: 106836676(MTOR)
MYB: 102241670(MTOR)
MYD: 102766933(MTOR)
MMYO: 118675322(MTOR)
MNA: 107540994(MTOR)
HAI: 109381262(MTOR)
DRO: 112299108(MTOR)
SHON: 118986352(MTOR)
AJM: 119064071(MTOR)
MMF: 118627075(MTOR)
PALE: 102885092(MTOR)
RAY: 107513109(MTOR)
MJV: 108390746(MTOR) 108399184
TOD: 119235686(MTOR)
LAV: 100660112(MTOR)
TMU: 101343808
MDO: 100619675(MTOR)
SHR: 100931480(MTOR)
PCW: 110199207(MTOR)
OAA: 100079751(MTOR)
GGA: 419455(MTOR)
PCOC: 116242610(MTOR)
MGP: 100547037(MTOR)
CJO: 107323407(MTOR)
NMEL: 110408585(MTOR)
APLA: 101802486(MTOR)
ACYG: 106040228(MTOR)
TGU: 100219695(MTOR)
LSR: 110474443(MTOR)
SCAN: 103820856(MTOR)
PMOA: 120496727(MTOR)
GFR: 102034190(MTOR)
FAB: 101820693(MTOR)
PHI: 102108233(MTOR)
PMAJ: 107213730(MTOR)
CCAE: 111938583(MTOR)
CCW: 104693234(MTOR)
ETL: 114056898(MTOR)
FPG: 101919512(MTOR)
FCH: 102051979(MTOR)
CLV: 102093827(MTOR)
EGZ: 104133077(MTOR)
NNI: 104008993(MTOR)
ACUN: 113487804(MTOR)
PADL: 103918043(MTOR)
AAM: 106482444(MTOR)
ASN: 102372197(MTOR)
AMJ: 102574334(MTOR)
CPOO: 109314475(MTOR)
GGN: 109293674(MTOR)
PSS: 102451030(MTOR)
CMY: 102947284(MTOR)
CPIC: 101949839(MTOR)
TST: 117867798(MTOR)
CABI: 116821919(MTOR)
ACS: 100565267(mtor)
PVT: 110073225(MTOR)
PBI: 103053332(MTOR)
PMUR: 107294607(MTOR)
TSR: 106548093(MTOR)
PGUT: 117673062(MTOR)
PMUA: 114602439(MTOR)
ZVI: 118085940(MTOR)
GJA: 107108920(MTOR)
XLA: 108696363
XTR: 100491970(mtor)
NPR: 108789092(MTOR) 108796319
DRE: 324254(mtor)
SANH: 107679101 107687131(mtor)
CCAR: 109052678 109094977(mtor)
CAUA: 113097237(mtor)
IPU: 108265039(mtor)
PHYP: 113533236(mtor)
AMEX: 103042377(mtor)
EEE: 113584326(mtor)
TRU: 101074470(mtor)
LCO: 104919512(mtor)
NCC: 104956725
ELY: 117258353(mtor)
PLEP: 121946537(mtor)
SLUC: 116040665(mtor)
ECRA: 117947276(mtor)
PFLV: 114558188(mtor)
GAT: 120829137(mtor)
MSAM: 119905919
CUD: 121517172(mtor)
MZE: 101471360(mtor)
ONL: 100700382(mtor)
OAU: 116317401(mtor)
OLA: 101156248(mtor)
OML: 112158714(mtor)
XMA: 102220301(mtor)
XCO: 114146827(mtor)
XHE: 116719879(mtor)
PRET: 103467091(mtor)
CVG: 107086709(mtor)
CTUL: 119786494(mtor)
NFU: 107391286(mtor)
KMR: 108233102(mtor)
ALIM: 106518905(mtor)
AOCE: 111567358(mtor)
CSEM: 103384900(mtor)
POV: 109630582(mtor)
LCF: 108882623(mtor)
SDU: 111227586(mtor)
SLAL: 111656119(mtor)
XGL: 120803615(mtor)
HCQ: 109511770(mtor)
BPEC: 110157966(mtor)
MALB: 109967123(mtor)
SASA: 100380849(mtor)
OMY: 100136723(mtor)
SALP: 112068245
ELS: 105013925(mtor)
PKI: 111834305(mtor)
LOC: 102692856(mtor)
LCM: 102360124(MTOR)
CMK: 103181362(mtor)
RTP: 109914403
BFO: 118430523
CIN: 100178479
SCLV: 120344265
SPU: 580879
APLC: 110982650
SKO: 100329005(TOR)
DME: Dmel_CG5092(Tor)
DER: 6541133
DSE: 6617786
DSI: Dsimw501_GD23862(Dsim_GD23862)
DAN: 6497044
DPE: 6602261
DMN: 108162417
DWI: 6642343
DAZ: 108611317
DNV: 108649829
DHE: 111592907
DVI: 6627365
MDE: 101893055
LCQ: 111683351
ACOZ: 120958476
AARA: 120901989
AAG: 5565894
AALB: 109429896
AME: 409393
ACER: 107995862
BIM: 100749875
BTER: 100649664
CCAL: 108631239
OBB: 114873371
MGEN: 117230032
NMEA: 116434696
CGIG: 122397130
SOC: 105193564
MPHA: 105830377
AEC: 105152845
ACEP: 105624966
PBAR: 105424520
VEM: 105566956
HST: 105190144
DQU: 106747690
CFO: 105256945
FEX: 115242561
LHU: 105679357
PGC: 109859730
OBO: 105276125
PCF: 106789371
NVI: 100118360
CSOL: 105365573
MDL: 103576490
TCA: 660499
DPA: 109544499
ATD: 109608742
AGB: 108911584
NVL: 108556975
APLN: 108742376
PPYR: 116177660
OTU: 111419246
BMOR: 100431180(TOR2)
PXY: 105390151
API: 100163481
DNX: 107162479
AGS: 114123865
RMD: 113555205
BTAB: 109043116
DCI: 103508150
CLEC: 106669228
NLU: 111055114
ZNE: 110840625
CSEC: 111869020
FCD: 110851607
PVM: 113820097
HAME: 121869067
EAF: 111702618
DSV: 119446821
RMP: 119183826
VDE: 111250846
VJA: 111258678
TUT: 107359769
DPTE: 113791191
CSCU: 111620923
PTEP: 107439010
SDM: 118200492
CEL: CELE_B0261.2(let-363)
CBR: CBG12850(Cbr-let-363)
BMY: BM_BM1727(Bm1727)
TSP: Tsp_04731
PCAN: 112557789
BGT: 106074018
GAE: 121390027
CRG: 105331599
MYI: 110448263
PMAX: 117314650
OBI: 106870424
EGL: EGR_00240
NVE: 5517009
EPA: 110251691
ATEN: 116299226
AMIL: 114959968
PDAM: 113680191
SPIS: 111343488
DGT: 114516375
HMG: 100197178
AQU: 100633443
ATH: AT1G50030(TOR)
ALY: 9330289
CRB: 17897805
CSAT: 104777927
THJ: 104826500
CPAP: 110821135
CIT: 102618367
PVY: 116132315
TCC: 18608126
DZI: 111309034
EGR: 104419800
VRA: 106777509
VAR: 108319939
VUN: 114173244
CCAJ: 109800697
APRC: 113869948
CAM: 101499541
LJA: Lj1g3v0052210.1(Lj1g3v0052210.1) Lj1g3v0052210.2(Lj1g3v0052210.2) Lj1g3v0052210.3(Lj1g3v0052210.3)
ADU: 107488658
AIP: 107643288
FVE: 101310491
RCN: 112168819
PPER: 18766256
PMUM: 103335031
PAVI: 110760196
PDUL: 117636375
PXB: 103928072
ZJU: 107427093
MNT: 21387265
CSV: 101212051
CMO: 103495325
BHJ: 120069804
MCHA: 111017367
CMAX: 111471047
CMOS: 111454906
CPEP: 111811251
RCU: 8258060
HBR: 110648417
MESC: 110618927
QLO: 115968055
TWL: 119982056
VVI: 100249713
VRI: 117910833
SLY: 101259295
SPEN: 107002769
SOT: 102604383
CANN: 107879481
NTA: 107776741(TOR) 107799667
NSY: 104242814
NTO: 104118002
NAU: 109208101
INI: 109178500
ITR: 116013600
SIND: 105169347
EGT: 105957460
LSV: 111891370
CCAV: 112515141
CSIN: 114265111
BVG: 104904834
NNU: 104589114
MING: 122091291
NCOL: 116251225
OSA: 4338174
DOSA: Os05t0235300-01(Os05g0235300)
OBR: 102706940
BDI: 100835842
ATS: 109783936
SBI: 8084725
ZMA: 542211(cl3114_1(600))
SITA: 101780377
PHAI: 112886367
PDA: 103698521
EGU: 105056261
MUS: 103980358
DCT: 110111565
PEQ: 110022180
AOF: 109833837
ATR: 18423738
PPP: 112284079
APRO: F751_1983
MIS: MICPUN_88899(TOR)
SCE: YJR066W(TOR1) YKL203C(TOR2)
ERC: Ecym_3152
KMX: KLMA_30046(TOR2)
NCS: NCAS_0G03440(NCAS0G03440)
NDI: NDAI_0D01470(NDAI0D01470)
TPF: TPHA_0F03570(TPHA0F03570)
TBL: TBLA_0D03670(TBLA0D03670)
TDL: TDEL_0F00460(TDEL0F00460)
KAF: KAFR_0A08100(KAFR0A08100) KAFR_0E00310(KAFR0E00310)
PIC: PICST_33151(TOR2)
CAL: CAALFM_C207330WA(TOR1)
SLB: AWJ20_2811(TOR1)
NCR: NCU05608
NTE: NEUTE1DRAFT148627(NEUTE1DRAFT_148627)
MGR: MGG_15156
SSCK: SPSK_06845
MAW: MAC_01551
MAJ: MAA_02388
CMT: CCM_04900
MBE: MBM_05946
ANI: AN5982.2
ANG: ANI_1_672144(An16g04720)
ABE: ARB_05798
TVE: TRV_04550
PNO: SNOG_08246(SNOG_08245)
PTE: PTT_08717
ZTR: MYCGRDRAFT_67795(TOR1)
PFJ: MYCFIDRAFT_205476(TOR2)
SPO: SPBC216.07c(tor2) SPBC30D10.10c(tor1)
TASA: A1Q1_03117
ABP: AGABI1DRAFT126075(AGABI1DRAFT_126075) AGABI1DRAFT35543(AGABI1DRAFT_35543)
ABV: AGABI2DRAFT151451(AGABI2DRAFT_151451) AGABI2DRAFT151460(AGABI2DRAFT_151460)
MGL: MGL_2920
MRT: MRET_3521
DDI: DDB_G0281569(tor)
DFA: DFA_09983(tor)
EHI: EHI_169320(177.t00028)
SPAR: SPRG_13345
EHX: EMIHUDRAFT_99823(TOR1)
LMA: LMJF_34_3940(TOR3) LMJF_34_4530(TOR2) LMJF_36_6320(TOR1)
LIF: LINJ_34_3750(TOR3) LINJ_34_4160(TOR2) LINJ_36_6580(TOR1)
LBZ: LBRM_20_3550(TOR3) LBRM_20_3990(TOR2) LBRM_35_6620(TOR1)
 » show all
Reference
PMID:8008069
  Authors
Brown EJ, Albers MW, Shin TB, Ichikawa K, Keith CT, Lane WS, Schreiber SL
  Title
A mammalian protein targeted by G1-arresting rapamycin-receptor complex.
  Journal
Nature 369:756-8 (1994)
DOI:10.1038/369756a0
  Sequence
[hsa:2475]
Reference
  Authors
Jiang Y, Broach JR
  Title
Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.
  Journal
EMBO J 18:2782-92 (1999)
DOI:10.1093/emboj/18.10.2782
LinkDB

KEGG   ORTHOLOGY: K07204
Entry
K07204                      KO                                     

Name
RAPTOR
Definition
regulatory associated protein of mTOR
Pathway
map04136  Autophagy - other
map04138  Autophagy - yeast
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04714  Thermogenesis
map04910  Insulin signaling pathway
map05131  Shigellosis
map05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K07204  RAPTOR; regulatory associated protein of mTOR
   04152 AMPK signaling pathway
    K07204  RAPTOR; regulatory associated protein of mTOR
   04150 mTOR signaling pathway
    K07204  RAPTOR; regulatory associated protein of mTOR
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K07204  RAPTOR; regulatory associated protein of mTOR
   04138 Autophagy - yeast
    K07204  RAPTOR; regulatory associated protein of mTOR
   04136 Autophagy - other
    K07204  RAPTOR; regulatory associated protein of mTOR
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07204  RAPTOR; regulatory associated protein of mTOR
  09149 Aging
   04211 Longevity regulating pathway
    K07204  RAPTOR; regulatory associated protein of mTOR
   04213 Longevity regulating pathway - multiple species
    K07204  RAPTOR; regulatory associated protein of mTOR
  09159 Environmental adaptation
   04714 Thermogenesis
    K07204  RAPTOR; regulatory associated protein of mTOR
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K07204  RAPTOR; regulatory associated protein of mTOR
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K07204  RAPTOR; regulatory associated protein of mTOR
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07204  RAPTOR; regulatory associated protein of mTOR
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    K07204  RAPTOR; regulatory associated protein of mTOR
Other DBs
COG: COG2319
Genes
HSA: 57521(RPTOR)
PTR: 454949(RPTOR)
PPS: 100976440(RPTOR)
GGO: 101137206(RPTOR)
PON: 100434731(RPTOR)
NLE: 100587259(RPTOR)
MCC: 712848(RPTOR)
MCF: 102116460(RPTOR)
CSAB: 103243701(RPTOR)
CATY: 105588623(RPTOR)
PANU: 101022424(RPTOR)
RRO: 104654941(RPTOR)
RBB: 108534267(RPTOR)
TFN: 117066804(RPTOR)
PTEH: 111542542(RPTOR)
CJC: 100413313(RPTOR)
SBQ: 101039601(RPTOR)
MMUR: 105884979(RPTOR)
MMU: 74370(Rptor)
MCAL: 110304213(Rptor)
MPAH: 110331504(Rptor)
RNO: 287871(Rptor)
MCOC: 116077504(Rptor)
MUN: 110550003(Rptor)
CGE: 100761529(Rptor)
PLEU: 114680595(Rptor)
NGI: 103730533(Rptor)
HGL: 101724257(Rptor)
CCAN: 109689889(Rptor)
OCU: 103346553
TUP: 102470795(RPTOR)
CFA: 608378(RPTOR)
VVP: 112920880(RPTOR)
VLG: 121472564(RPTOR)
AML: 100478081(RPTOR)
UMR: 103665983(RPTOR)
UAH: 113244532(RPTOR)
ORO: 101384799(RPTOR)
ELK: 111160429
MPUF: 101685477(RPTOR)
EJU: 114216073(RPTOR)
MLX: 118024187(RPTOR)
FCA: 101086862(RPTOR)
PTG: 102958566(RPTOR)
PPAD: 109276800(RPTOR)
AJU: 106981870(RPTOR)
HHV: 120228136(RPTOR)
BTA: 507056(RPTOR)
BOM: 102285390(RPTOR)
BIU: 109573755(RPTOR)
BBUB: 102412399(RPTOR)
CHX: 102173122(RPTOR)
OAS: 101119321(RPTOR)
ODA: 120866846(RPTOR)
SSC: 100512677(RPTOR)
CFR: 102512403(RPTOR)
CDK: 105106263(RPTOR)
BACU: 103001225(RPTOR)
LVE: 103088660(RPTOR)
OOR: 101290397(RPTOR)
DLE: 111182724(RPTOR)
PCAD: 102990076(RPTOR)
ECB: 100056244(RPTOR)
EPZ: 103547320(RPTOR)
EAI: 106845645(RPTOR)
MYB: 102240594(RPTOR)
MYD: 102754661(RPTOR)
MMYO: 118671632(RPTOR)
MNA: 107532063(RPTOR)
HAI: 109393012(RPTOR)
DRO: 112298706(RPTOR)
SHON: 119002425(RPTOR)
AJM: 119058513(RPTOR)
MMF: 118633821(RPTOR)
PALE: 102885334(RPTOR)
RAY: 107510093(RPTOR)
MJV: 108398121(RPTOR)
TOD: 119232762(RPTOR)
LAV: 100657753
TMU: 101343081
MDO: 100026103(RPTOR)
SHR: 100930970(RPTOR)
PCW: 110218186(RPTOR)
GGA: 428674(RPTOR)
PCOC: 116232521(RPTOR)
MGP: 100549898(RPTOR)
CJO: 107322223(RPTOR)
NMEL: 110407207(RPTOR)
ACYG: 106046774(RPTOR)
TGU: 100225993(RPTOR)
LSR: 110472422(RPTOR)
SCAN: 103819746(RPTOR)
PMOA: 120505455(RPTOR)
GFR: 102035893(RPTOR)
FAB: 101813847(RPTOR)
PHI: 102110286(RPTOR)
PMAJ: 107212280(RPTOR)
CCAE: 111937466(RPTOR)
CCW: 104698217(RPTOR)
ETL: 114068210(RPTOR)
FPG: 101914030(RPTOR)
FCH: 102056258(RPTOR)
CLV: 102083854(RPTOR)
EGZ: 104130570(RPTOR)
NNI: 104014273(RPTOR)
ACUN: 113486697(RPTOR)
PADL: 103917403(RPTOR)
AAM: 106485995(RPTOR)
ASN: 102388292(RPTOR)
AMJ: 102566392(RPTOR)
CPOO: 109314901(RPTOR)
GGN: 109296289(RPTOR)
PSS: 102450550(RPTOR)
CMY: 102940371(RPTOR)
CPIC: 101943607(RPTOR)
TST: 117887235(RPTOR)
CABI: 116834885(RPTOR)
ACS: 100560434(rptor)
PVT: 110090060(RPTOR)
PBI: 103048711(RPTOR)
PMUR: 107286684(RPTOR)
TSR: 106545772
PGUT: 117663109(RPTOR)
PMUA: 114588922(RPTOR)
ZVI: 118079695(RPTOR)
GJA: 107108212(RPTOR)
XLA: 108700989
XTR: 100170605(rptor)
NPR: 108795291(RPTOR)
DRE: 560455(rptor)
SRX: 107710275(rptor) 107728013
SANH: 107669526 107701211(rptor)
SGH: 107553319 107591918(rptor)
CCAR: 109080016
CAUA: 113071303(rptor)
IPU: 108272627(rptor)
PHYP: 113523684(rptor)
AMEX: 103025211(rptor)
EEE: 113578854(rptor)
TRU: 115253237(rptor)
LCO: 104921544(rptor)
ELY: 117255147(rptor)
PLEP: 121941941(rptor)
SLUC: 116039645(rptor)
ECRA: 117956134(rptor)
PFLV: 114547407(rptor)
GAT: 120824991(rptor)
MSAM: 119899739(rptor)
CUD: 121508202(rptor)
MZE: 101472178(rptor)
ONL: 100703173(rptor)
OAU: 116331481(rptor)
OLA: 101156464(rptor)
OML: 112156982(rptor)
XMA: 102218020(rptor)
XCO: 114144230(rptor)
XHE: 116719966(rptor)
PRET: 103463551(rptor)
CVG: 107085497(rptor)
CTUL: 119779336(rptor)
NFU: 107390202(rptor)
KMR: 108248226(rptor)
ALIM: 106526906
AOCE: 111567444(rptor)
CSEM: 103384286(rptor)
POV: 109627313(rptor)
LCF: 108884551(rptor)
SDU: 111217934(rptor)
SLAL: 111655458(rptor)
XGL: 120799911(rptor)
HCQ: 109527445(rptor)
BPEC: 110173825(rptor)
MALB: 109956793(rptor)
SALP: 111982470(rptor) 112080951
ELS: 105021612(rptor)
SFM: 108940088(rptor)
PKI: 111832912(rptor)
LOC: 102682722(rptor)
LCM: 102347131(RPTOR)
CMK: 103175567(rptor)
RTP: 109929749(rptor)
BFO: 118429076
CIN: 100176030
SCLV: 120340724
SPU: 586135
APLC: 110980200
SKO: 100329056(Rptor)
DME: Dmel_CG4320(raptor)
DER: 26526319
DSE: 116801997
DSI: Dsimw501_GD16213(Dsim_GD16213)
DAN: 26513892
DSR: 110182073
DPE: 113566507
DMN: 108158608
DWI: 26529589
DNV: 115562295
MDE: 109611603
LCQ: 111677467
ACOZ: 120955315
AARA: 120899917
AALB: 109622875
AME: 551668
ACER: 108002381
BIM: 100747046
BTER: 100646513
CCAL: 108625095
OBB: 114875182
MGEN: 117225495
NMEA: 116425775
CGIG: 122404916
SOC: 105205268
AEC: 105143266
ACEP: 105622426
PBAR: 105427154
VEM: 105560656
HST: 105188175
DQU: 106743346
CFO: 105255545
FEX: 115235920
LHU: 105671423
PGC: 109858433
OBO: 105279550
PCF: 106792114
NVI: 100121829
CSOL: 105362360
MDL: 103574178
TCA: 658299
DPA: 109544960
ATD: 109608878
AGB: 108907262
NVL: 108567042
APLN: 108737257
PPYR: 116178059
OTU: 111426217
BMOR: 100463495(rptor)
BMAN: 114244624
MSEX: 115448755
BANY: 112051461
PMAC: 106721370
PXU: 106119010
PRAP: 111002364
ZCE: 119832407
HAW: 110381466
TNL: 113508095
PXY: 105383216
API: 100167375
DNX: 107168561
AGS: 114120868
RMD: 113550891
BTAB: 109037964
CLEC: 106673798
NLU: 111047193
ZNE: 110832472
CSEC: 111873291
FCD: 110848463
PVM: 113809344
HAME: 121868544
EAF: 111695617
VDE: 111248206
VJA: 111271908
TUT: 107368329
DPTE: 113798080
CSCU: 111634668
PTEP: 107450389
SDM: 118191731
CEL: CELE_C10C5.6(daf-15)
CBR: CBG21644(Cbr-daf-15)
BMY: BM_BM2128(Bma-daf-15)
PCAN: 112558153
BGT: 106055319
CRG: 105317543
MYI: 110448552
PMAX: 117338746
OBI: 106869827
EGL: EGR_07620
NVE: 5520151
EPA: 110238896
ATEN: 116288948
ADF: 107355961
AMIL: 114957656
PDAM: 113667746
SPIS: 111325425
DGT: 114519261
HMG: 100213041
AQU: 100638632
ATH: AT3G08850(RAPTOR1) AT5G01770(RAPTOR2)
CRB: 17890879
CPAP: 110811611
CIT: 102614941
PVY: 116125960
TCC: 18602269
VRA: 106759187
VAR: 108328977
VUN: 114183537
APRC: 113861026
CAM: 101514864
LJA: Lj1g3v2442920.1(Lj1g3v2442920.1) Lj1g3v2442920.2(Lj1g3v2442920.2) Lj1g3v2442920.4(Lj1g3v2442920.4)
FVE: 101302666
RCN: 112192223
PPER: 18774912
PMUM: 103343577
PAVI: 110768387
PDUL: 117631841
ZJU: 107431283
MNT: 21404824
CSV: 101210550
BHJ: 120073011
MCHA: 111013788
JCU: 105648064
QLO: 115953816
VVI: 100261889
VRI: 117919659
SPEN: 107031079
CANN: 107842546
INI: 109181636
ITR: 116006523
OEU: 111407995
EGT: 105953157
LSV: 111898220
CCAV: 112518569
BVG: 104898214
SOE: 110790221
NCOL: 116248113
DOSA: Os11t0109933-01(Os11g0109933) Os12t0110000-00(Os12g0110000)
OBR: 102700397
BDI: 100844309
ATS: 109780879
PEQ: 110035938
ATR: 18433549
MNG: MNEG_4146
APRO: F751_5412
SCE: YHR186C(KOG1)
KMX: KLMA_10476(KOG1)
NCS: NCAS_0F02050(NCAS0F02050)
NDI: NDAI_0C03540(NDAI0C03540)
TPF: TPHA_0L02130(TPHA0L02130)
TBL: TBLA_0B04680(TBLA0B04680)
TDL: TDEL_0G00730(TDEL0G00730)
KAF: KAFR_0B01580(KAFR0B01580)
PIC: PICST_74320(KOG1)
CAL: CAALFM_C105460WA(KOG1)
SLB: AWJ20_4695(KOG1)
NCR: NCU00621
NTE: NEUTE1DRAFT74339(NEUTE1DRAFT_74339)
MGR: MGG_02874
SSCK: SPSK_08295
MAW: MAC_00869
MAJ: MAA_07359
CMT: CCM_03247
BFU: BCIN_06g02850(Bckog1)
MBE: MBM_09848
ANI: AN4639.2
ANG: ANI_1_1874064(An07g06130)
ABE: ARB_03447
TVE: TRV_06101
PNO: SNOG_00356(SNOG_00357)
PTE: PTT_09949
SPO: SPAC57A7.11(mip1)
TASA: A1Q1_02297
ABP: AGABI1DRAFT67693(AGABI1DRAFT_67693)
ABV: AGABI2DRAFT147275(AGABI2DRAFT_147275)
MGL: MGL_3387
MRT: MRET_1849
DDI: DDB_G0270398(raptor)
DFA: DFA_05671(raptor)
EHI: EHI_040260(144.t00022)
NGD: NGA_0699600(RAPTOR)
 » show all
Reference
  Authors
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM
  Title
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
  Journal
Cell 110:163-75 (2002)
DOI:10.1016/S0092-8674(02)00808-5
  Sequence
[hsa:57521]
Reference
  Authors
Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K
  Title
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.
  Journal
Cell 110:177-89 (2002)
DOI:10.1016/S0092-8674(02)00833-4
  Sequence
[hsa:57521]
LinkDB

KEGG   ORTHOLOGY: K16184
Entry
K16184                      KO                                     

Name
AKT1S1, PRAS40
Definition
proline-rich AKT1 substrate 1
Pathway
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04152  AMPK signaling pathway
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04714  Thermogenesis
map05131  Shigellosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
   04150 mTOR signaling pathway
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
   04213 Longevity regulating pathway - multiple species
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
Genes
HSA: 84335(AKT1S1)
PTR: 456218(AKT1S1)
PPS: 100981524(AKT1S1)
GGO: 101151809(AKT1S1)
PON: 100449244(AKT1S1)
NLE: 100606336(AKT1S1)
MCC: 719101(AKT1S1)
MCF: 102139860(AKT1S1)
CSAB: 103235060(AKT1S1)
CATY: 105595312(AKT1S1)
PANU: 101022446(AKT1S1)
RRO: 104667216(AKT1S1)
RBB: 108535813(AKT1S1)
TFN: 117091606(AKT1S1)
PTEH: 111519922(AKT1S1)
CJC: 100385926(AKT1S1)
SBQ: 101035426(AKT1S1)
MMUR: 105865626(AKT1S1)
MMU: 67605(Akt1s1)
MCAL: 110299208(Akt1s1)
MPAH: 110324411(Akt1s1)
RNO: 292887(Akt1s1)
MCOC: 116102150(Akt1s1)
CGE: 100768286(Akt1s1)
PLEU: 114684368(Akt1s1)
NGI: 103743684(Akt1s1)
HGL: 101712955(Akt1s1)
CCAN: 109683918(Akt1s1)
TUP: 102485528(AKT1S1)
CFA: 610130(AKT1S1)
VVP: 112931404(AKT1S1)
VLG: 121484108(AKT1S1)
AML: 109489401(AKT1S1)
UMR: 103657265(AKT1S1)
UAH: 113243278(AKT1S1)
ORO: 101366130(AKT1S1)
ELK: 111160809
MPUF: 101683323(AKT1S1)
EJU: 114199635(AKT1S1)
MLX: 117998320(AKT1S1)
FCA: 101100932(AKT1S1)
PPAD: 109253038(AKT1S1)
AJU: 106983118(AKT1S1)
HHV: 120240444(AKT1S1)
BTA: 514859(AKT1S1)
BOM: 102264796(AKT1S1)
BIU: 109572134(AKT1S1)
BBUB: 102395301(AKT1S1)
CHX: 102186333(AKT1S1)
OAS: 101109114(AKT1S1)
ODA: 120872112(AKT1S1)
SSC: 100519715(AKT1S1)
CFR: 102515969(AKT1S1)
CDK: 105100186(AKT1S1)
BACU: 103005941(AKT1S1)
LVE: 103075856(AKT1S1)
OOR: 101289949(AKT1S1)
DLE: 111180592(AKT1S1)
PCAD: 102990917(AKT1S1)
ECB: 100052282(AKT1S1)
EPZ: 103558294(AKT1S1)
EAI: 106824154(AKT1S1)
MYB: 102243802(AKT1S1)
MYD: 102758931(AKT1S1)
MMYO: 118655365(AKT1S1)
MNA: 107531871(AKT1S1)
HAI: 109391032(AKT1S1)
DRO: 112310069(AKT1S1)
AJM: 119050615(AKT1S1) 119059915
MMF: 118638271(AKT1S1)
PALE: 102897877(AKT1S1)
RAY: 107498836(AKT1S1)
MJV: 108383352(AKT1S1)
TOD: 119249606(AKT1S1)
LAV: 100671446(AKT1S1)
TMU: 101345300
MDO: 100030158(AKT1S1)
SHR: 100928550(AKT1S1)
PCW: 110219791(AKT1S1)
OAA: 114814792(AKT1S1)
ASN: 102367984(AKT1S1)
AMJ: 102558199(AKT1S1)
CPIC: 101938133(AKT1S1)
ACS: 100557925(akt1s1)
PVT: 110078574(AKT1S1)
PBI: 103049186(AKT1S1)
TSR: 106549271(AKT1S1) 106556088
PGUT: 117669131(AKT1S1)
PMUA: 114608013(AKT1S1)
ZVI: 118094468(AKT1S1)
GJA: 107116605(AKT1S1)
XLA: 431814(akt1s1.S) 495075(akt1s1.L)
XTR: 496515(akt1s1)
NPR: 108792627(AKT1S1)
DRE: 566559(akt1s1)
CCAR: 109109154
IPU: 108280807(akt1s1)
PHYP: 113528230(akt1s1)
AMEX: 111193360(akt1s1)
EEE: 113587138(akt1s1)
LCO: 104939070(akt1s1)
NCC: 104954396(akt1s1)
ELY: 117268340(akt1s1)
PLEP: 121957065(akt1s1)
SLUC: 116063717(akt1s1)
ECRA: 117957591(akt1s1)
PFLV: 114570346(akt1s1)
GAT: 120827382(akt1s1)
MSAM: 119894016(akt1s1)
CUD: 121529436(akt1s1)
MZE: 101481934(akt1s1)
ONL: 100689736(akt1s1)
OAU: 116328999(akt1s1)
OLA: 101169289(akt1s1)
OML: 112146580(akt1s1)
XMA: 102221079(akt1s1)
XCO: 114159983(akt1s1)
XHE: 116735590(akt1s1)
PRET: 103468981(akt1s1)
CVG: 107097127(akt1s1)
CTUL: 119791295(akt1s1)
NFU: 107378483(akt1s1)
KMR: 108237767(akt1s1)
AOCE: 111572742(akt1s1)
CSEM: 103392853(akt1s1)
POV: 109634335(akt1s1)
LCF: 108880633(akt1s1)
SDU: 111217583(akt1s1)
SLAL: 111660518(akt1s1)
XGL: 120787846(akt1s1)
HCQ: 109527791(akt1s1)
BPEC: 110161314(akt1s1)
MALB: 109963177(akt1s1)
OTW: 112258995
ELS: 105012938(akt1s1)
SFM: 108941800(akt1s1)
PKI: 111836870(akt1s1)
LOC: 102683567(akt1s1)
PSPA: 121306008(akt1s1)
LCM: 102354837(AKT1S1)
CMK: 103173667(akt1s1)
RTP: 109923030(akt1s1)
BFO: 118412296
CIN: 100176540
APLC: 110975487
SKO: 100379062
AME: 551512
BIM: 100746742
BTER: 100645428
CCAL: 108622323
OBB: 114874712
MGEN: 117218460
NMEA: 116428693
SOC: 105198761
ACEP: 105618850
PBAR: 105427247
HST: 105189811
DQU: 106747449
CFO: 105249652
LHU: 105673603
PGC: 109853289
NVI: 100217361(Lobe)
CSOL: 105365101
NVL: 108559757
BTAB: 109043844
CLEC: 106669992
NLU: 111046277
EAF: 111706424
DSV: 119450935
RSAN: 119384158
VDE: 111252077
VJA: 111272888
TUT: 107362660
PTEP: 107444734
SDM: 118200099
GAE: 121381273
MYI: 110449090
PMAX: 117336208
OBI: 106873180
NVE: 5508361
EPA: 110245043
ATEN: 116286345
AMIL: 114958534
SPIS: 111326006
DGT: 114533702
HMG: 100206382
 » show all
Reference
  Authors
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM
  Title
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
  Journal
Mol Cell 25:903-15 (2007)
DOI:10.1016/j.molcel.2007.03.003
Reference
  Authors
Kovacina KS, Park GY, Bae SS, Guzzetta AW, Schaefer E, Birnbaum MJ, Roth RA
  Title
Identification of a proline-rich Akt substrate as a 14-3-3 binding partner.
  Journal
J Biol Chem 278:10189-94 (2003)
DOI:10.1074/jbc.M210837200
  Sequence
[hsa:84335]
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