KEGG   ORTHOLOGY: K07211
Entry
K07211                      KO                                     

Name
IKBKE, IKKE
Definition
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
Pathway
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04625  C-type lectin receptor signaling pathway
ko04657  IL-17 signaling pathway
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   04621 NOD-like receptor signaling pathway
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   04622 RIG-I-like receptor signaling pathway
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   04623 Cytosolic DNA-sensing pathway
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   04625 C-type lectin receptor signaling pathway
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   04657 IL-17 signaling pathway
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05160 Hepatitis C
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05171 Coronavirus disease - COVID-19
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05164 Influenza A
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05162 Measles
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05168 Herpes simplex virus 1 infection
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05169 Epstein-Barr virus infection
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
   05165 Human papillomavirus infection
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
Other DBs
GO: 0008384
Genes
HSA: 9641(IKBKE)
PTR: 742813(IKBKE)
PPS: 100992569(IKBKE)
GGO: 101125384(IKBKE)
PON: 100448480(IKBKE)
NLE: 100605137(IKBKE)
MCC: 695607(IKBKE)
MCF: 102126428(IKBKE)
CSAB: 103230198(IKBKE)
RRO: 104661734(IKBKE)
RBB: 108535149(IKBKE)
CJC: 100392518(IKBKE)
SBQ: 101027871(IKBKE)
MMU: 56489(Ikbke)
MCAL: 110301565(Ikbke)
MPAH: 110321718(Ikbke)
RNO: 363984(Ikbke)
MUN: 110550327(Ikbke)
CGE: 100761646(Ikbke)
NGI: 103725939(Ikbke)
HGL: 101697947(Ikbke)
CCAN: 109697216(Ikbke)
OCU: 100354455(IKBKE)
TUP: 102481203(IKBKE)
CFA: 478950(IKBKE)
VVP: 112914364(IKBKE)
AML: 100465112(IKBKE)
UMR: 103671004(IKBKE)
UAH: 113242466(IKBKE)
ORO: 101366827(IKBKE)
ELK: 111151174
FCA: 101086282(IKBKE)
PTG: 102963614(IKBKE)
PPAD: 109257640(IKBKE)
AJU: 106972924(IKBKE)
BTA: 533216(IKBKE)
BOM: 102271506(IKBKE)
BIU: 109570721(IKBKE)
BBUB: 102398659(IKBKE)
CHX: 102183809(IKBKE)
OAS: 101116923(IKBKE)
SSC: 100519508(IKBKE)
CFR: 102519234(IKBKE)
CDK: 105098613(IKBKE)
BACU: 103013616(IKBKE)
LVE: 103080924(IKBKE)
OOR: 101273673(IKBKE)
DLE: 111184753(IKBKE)
PCAD: 102994478(IKBKE)
ECB: 100055384(IKBKE)
EPZ: 103553835(IKBKE)
EAI: 106823378(IKBKE)
MYB: 102248515(IKBKE)
MYD: 102760291(IKBKE)
MNA: 107538891(IKBKE)
HAI: 109386512(IKBKE)
DRO: 112318201(IKBKE)
PALE: 102889768(IKBKE)
RAY: 107502229(IKBKE)
MJV: 108390202(IKBKE)
LAV: 100663886(IKBKE)
TMU: 101344779
MDO: 100019578(IKBKE)
SHR: 100934784(IKBKE)
PCW: 110219596(IKBKE)
OAA: 100077063(IKBKE)
GGA: 430480(IKBKE)
MGP: 100548215(IKBKE)
CJO: 107324928(IKBKE)
NMEL: 110388051(IKBKE)
APLA: 101800153(IKBKE)
ACYG: 106041301(IKBKE)
TGU: 100228860(IKBKE)
LSR: 110473091(IKBKE)
SCAN: 103822391(IKBKE)
GFR: 102043917(IKBKE)
FAB: 101814828(IKBKE)
PHI: 102105384(IKBKE)
PMAJ: 107214767(IKBKE)
CCAE: 111939780(IKBKE)
CCW: 104692514(IKBKE)
ETL: 114063148(IKBKE)
FPG: 101911668(IKBKE)
FCH: 102050482(IKBKE)
CLV: 102088357(IKBKE)
EGZ: 104134342(IKBKE)
NNI: 104013118(IKBKE)
ACUN: 113488792(IKBKE)
PADL: 103919787(IKBKE)
AAM: 106482786(IKBKE)
ASN: 102372815(IKBKE)
AMJ: 102560016(IKBKE)
PSS: 102464043(IKBKE)
CMY: 102930512(IKBKE)
CPIC: 101934458(IKBKE)
ACS: 100562496(ikbke)
PVT: 110088412(IKBKE)
PBI: 103055936(IKBKE)
PMUA: 114599921(IKBKE)
GJA: 107115324(IKBKE)
XLA: 108709484(ikbke.S) 734896(ikbke.L)
XTR: 100487744(ikbke)
DRE: 437024(ikbke)
SRX: 107728638 107739275
SANH: 107655948 107675825(ikbke)
SGH: 107555619 107590150
CCAR: 109087965
IPU: 108255225(ikbke)
PHYP: 113539673(ikbke)
AMEX: 103047687(ikbke)
EEE: 113579176
TRU: 101074146(ikbke)
TNG: GSTEN00014007G001
LCO: 104925246(ikbke)
NCC: 104959970(ikbke)
MZE: 101472997(ikbke)
ONL: 100695544(ikbke)
OLA: 101168283(ikbke)
XMA: 102228722
XCO: 114135317
PRET: 103464875(ikbke)
CVG: 107083313(ikbke)
NFU: 107385596(ikbke)
KMR: 108235567(ikbke)
ALIM: 106513309(ikbke)
AOCE: 111566565(ikbke)
CSEM: 103386082(ikbke)
POV: 109643466
LCF: 108890009(ikbke)
SDU: 111221468(ikbke)
SLAL: 111667666(ikbke)
HCQ: 109522194
BPEC: 110156014
MALB: 109956286
SASA: 106565715
SALP: 111969717 111969826
ELS: 105017402
SFM: 108938249(ikbke)
PKI: 111854439(ikbke)
LCM: 102364129(IKBKE)
CMK: 103182410(ikbke)
 » show all
Reference
  Authors
Shimada T, Kawai T, Takeda K, Matsumoto M, Inoue J, Tatsumi Y, Kanamaru A, Akira S
  Title
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases.
  Journal
Int Immunol 11:1357-62 (1999)
DOI:10.1093/intimm/11.8.1357
  Sequence
[hsa:9641]
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