KEGG   ORTHOLOGY: K07299
Entry
K07299                      KO                                     

Name
SLC2A1, GLUT1
Definition
MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
Pathway
map04066  HIF-1 signaling pathway
map04911  Insulin secretion
map04919  Thyroid hormone signaling pathway
map04920  Adipocytokine signaling pathway
map04922  Glucagon signaling pathway
map04931  Insulin resistance
map04976  Bile secretion
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05211  Renal cell carcinoma
map05230  Central carbon metabolism in cancer
map05415  Diabetic cardiomyopathy
Disease
H00232  Hereditary stomatocytosis
H00808  Idiopathic generalized epilepsies
H00831  Primary dystonia
H00836  GLUT1 deficiency syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
   04922 Glucagon signaling pathway
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
   04920 Adipocytokine signaling pathway
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
   04919 Thyroid hormone signaling pathway
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
  09154 Digestive system
   04976 Bile secretion
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
   05230 Central carbon metabolism in cancer
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC2: Facilitative GLUT transporter
   K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
 Major facilitator superfamily (MFS)
  Sugar transporters
   Sugar porter (SP) family
    K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
Other DBs
GO: 0005355
TC: 2.A.1.1.28
Genes
HSA: 6513(SLC2A1)
PTR: 100613619(SLC2A1)
PPS: 100991584(SLC2A1)
GGO: 101145851(SLC2A1)
PON: 100173447(SLC2A1)
NLE: 100594511(SLC2A1)
MCC: 698931(SLC2A1)
MCF: 102144217(SLC2A1)
CSAB: 103224987(SLC2A1)
CATY: 105594650(SLC2A1)
PANU: 100381181(SLC2A1)
RRO: 104669015(SLC2A1)
RBB: 108535710(SLC2A1)
TFN: 117092745(SLC2A1)
PTEH: 111548717(SLC2A1)
CJC: 100404544(SLC2A1)
SBQ: 101049410(SLC2A1)
MMUR: 105862274(SLC2A1)
MMU: 20525(Slc2a1)
MCAL: 110292203(Slc2a1)
MPAH: 110323020(Slc2a1)
RNO: 24778(Slc2a1)
MCOC: 116096528(Slc2a1)
MUN: 110547453(Slc2a1)
CGE: 100753506(Slc2a1)
PLEU: 114704945(Slc2a1)
NGI: 103741911(Slc2a1)
HGL: 101697875(Slc2a1)
CCAN: 109674851(Slc2a1)
OCU: 100125988(SLC2A1)
TUP: 102472725(SLC2A1)
CFA: 482437(SLC2A1)
VVP: 112908208(SLC2A1)
VLG: 121481063(SLC2A1)
AML: 100476930(SLC2A1)
UMR: 103670822(SLC2A1)
UAH: 113254800(SLC2A1)
ORO: 101365014(SLC2A1)
ELK: 111143335
MPUF: 101680003(SLC2A1)
EJU: 114224204(SLC2A1)
MLX: 118019532(SLC2A1)
FCA: 100127104(SLC2A1)
PTG: 102957363(SLC2A1)
PPAD: 109254908(SLC2A1)
AJU: 106970163(SLC2A1)
HHV: 120236080(SLC2A1)
BTA: 282356(SLC2A1)
BOM: 102278454(SLC2A1)
BIU: 109556419(SLC2A1)
BBUB: 102392377(SLC2A1)
CHX: 102174800(SLC2A1)
OAS: 443461(SLC2A1)
ODA: 120856308(SLC2A1)
SSC: 102164419(SLC2A1)
CFR: 102516476(SLC2A1)
CDK: 105090921(SLC2A1)
BACU: 103013089
LVE: 103080387(SLC2A1)
OOR: 101272071(SLC2A1)
DLE: 111175689(SLC2A1)
PCAD: 102979224(SLC2A1)
ECB: 100034080(SLC2A1)
EPZ: 103563236(SLC2A1)
EAI: 106847800(SLC2A1)
MYB: 102250015(SLC2A1)
MYD: 102766250(SLC2A1)
MMYO: 118675371(SLC2A1)
MNA: 107544367(SLC2A1)
HAI: 109383412(SLC2A1)
DRO: 112299413(SLC2A1)
SHON: 118977686(SLC2A1)
AJM: 119052239(SLC2A1)
MMF: 118626041(SLC2A1)
PALE: 102885620(SLC2A1)
RAY: 107508288(SLC2A1)
MJV: 108406715(SLC2A1)
TOD: 119235258(SLC2A1)
LAV: 100677089(SLC2A1)
TMU: 101346113
MDO: 100026702(SLC2A1)
SHR: 100915589(SLC2A1)
PCW: 110206215(SLC2A1)
OAA: 100074548(SLC2A1)
GGA: 396130(SLC2A1)
PCOC: 116238363(SLC2A1)
MGP: 100548312(SLC2A1)
CJO: 107323491(SLC2A1)
NMEL: 110408739(SLC2A1)
APLA: 101792621(SLC2A1)
ACYG: 106049732(SLC2A1)
TGU: 100222572(SLC2A1)
LSR: 110474449(SLC2A1)
SCAN: 103820862(SLC2A1)
PMOA: 120496778(SLC2A1)
GFR: 102045097(SLC2A1)
FAB: 101806135(SLC2A1)
PHI: 102105889(SLC2A1)
PMAJ: 107213771(SLC2A1)
CCAE: 111938548(SLC2A1)
CCW: 104698570(SLC2A1)
ETL: 114070824
FPG: 101918461(SLC2A1)
FCH: 102055078(SLC2A1)
CLV: 102092800(SLC2A1)
EGZ: 104134707(SLC2A1)
NNI: 104011197(SLC2A1)
ACUN: 113487946(SLC2A1)
PADL: 103926383(SLC2A1)
AAM: 106484476
ASN: 102374059(SLC2A1)
AMJ: 102569733(SLC2A1)
CPOO: 109314289(SLC2A1)
GGN: 109293573(SLC2A1)
PSS: 102461992(SLC2A1)
CMY: 102938870(SLC2A1)
CPIC: 101936562(SLC2A1) 103306487
TST: 117867868(SLC2A1)
CABI: 116835571
PVT: 110072700(SLC2A1)
PBI: 103056430(SLC2A1)
PMUR: 107291389(SLC2A1)
TSR: 106552972(SLC2A1)
PGUT: 117669651(SLC2A1)
PMUA: 114602328(SLC2A1)
ZVI: 118085891(SLC2A1)
GJA: 107121334(SLC2A1)
XLA: 108697841(slc2a1.S) 494763(slc2a1.L)
XTR: 779913(slc2a1)
NPR: 108802930
DRE: 100321338(slc2a1b) 100334818 555778(slc2a1a)
NCC: 104945183(slc2a1)
PLEP: 121947150 121953794 121959571(slc2a1b)
SLUC: 116051491(slc2a1b) 116057301 116058858
ECRA: 117935686 117943642(slc2a1b) 117948285
LCM: 102360358(SLC2A1)
RTP: 109917220(slc2a1)
APLC: 110986531
DME: Dmel_CG43946(Glut1)
DER: 6545127
DSI: Dsimw501_GD13586(Dsim_GD13586)
DSR: 110178592
DPE: 6603312
DMN: 108152190
MDE: 101889977
ACOZ: 120949832
AARA: 120898101
AAG: 5575494
CPII: 120418991
ACER: 107999331
AGB: 108908804
PPYR: 116181017
DPTE: 113797666
CEL: CELE_H17B01.1(fgt-1) CELE_R09B5.11(R09B5.11)
BMY: BM_BM6945(Bm6945) BM_BM8362(Bm8362)
PCAN: 112557166
GAE: 121373844
EGL: EGR_01567
AMIL: 114976350
SPIS: 111321499
DGT: 114520406
HMG: 100207539
AQU: 100631385
ERC: Ecym_2262
TPF: TPHA_0N01090(TPHA0N01090)
KAF: KAFR_0G03530(KAFR0G03530)
CNE: CNC02600
SPAR: SPRG_20110
 » show all
Reference
  Authors
Zhao FQ, Keating AF
  Title
Functional properties and genomics of glucose transporters.
  Journal
Curr Genomics 8:113-28 (2007)
DOI:10.2174/138920207780368187
Reference
  Authors
Wood IS, Trayhurn P
  Title
Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.
  Journal
Br J Nutr 89:3-9 (2003)
DOI:10.1079/BJN2002763
Reference
PMID:3839598
  Authors
Mueckler M, Caruso C, Baldwin SA, Panico M, Blench I, Morris HR, Allard WJ, Lienhard GE, Lodish HF
  Title
Sequence and structure of a human glucose transporter.
  Journal
Science 229:941-5 (1985)
DOI:10.1126/science.3839598
  Sequence
[hsa:6513]
LinkDB

KEGG   ORTHOLOGY: K07593
Entry
K07593                      KO                                     

Name
SLC2A2, GLUT2
Definition
MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Pathway
map04911  Insulin secretion
map04917  Prolactin signaling pathway
map04922  Glucagon signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04950  Maturity onset diabetes of the young
map04973  Carbohydrate digestion and absorption
map05230  Central carbon metabolism in cancer
Disease
H00069  Glycogen storage disease
H01947  Fanconi-Bickel syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04922 Glucagon signaling pathway
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04917 Prolactin signaling pathway
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04950 Maturity onset diabetes of the young
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04931 Insulin resistance
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC2: Facilitative GLUT transporter
   K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
 Major facilitator superfamily (MFS)
  Sugar transporters
   Sugar porter (SP) family
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Other DBs
GO: 0005355
TC: 2.A.1.1.29
Genes
HSA: 6514(SLC2A2)
PTR: 460848(SLC2A2)
PPS: 100983878(SLC2A2)
GGO: 101126141(SLC2A2)
PON: 100437366(SLC2A2)
NLE: 100603133(SLC2A2)
MCC: 695538(SLC2A2)
MCF: 102130700(SLC2A2)
CSAB: 103221255(SLC2A2)
CATY: 105586069(SLC2A2)
PANU: 101022043(SLC2A2)
RRO: 104660535(SLC2A2)
RBB: 108515004(SLC2A2)
TFN: 117083729(SLC2A2)
PTEH: 111543526(SLC2A2)
CJC: 100397713(SLC2A2)
SBQ: 101053596(SLC2A2)
MMUR: 105855416(SLC2A2)
MMU: 20526(Slc2a2)
MCAL: 110291094(Slc2a2)
MPAH: 110320473(Slc2a2)
RNO: 25351(Slc2a2)
MCOC: 116095027(Slc2a2)
MUN: 110545687(Slc2a2)
CGE: 100750908(Slc2a2)
PLEU: 114697557(Slc2a2)
NGI: 103731696(Slc2a2)
HGL: 101699012(Slc2a2)
CCAN: 109682261(Slc2a2)
OCU: 100338918(SLC2A2)
TUP: 102497006(SLC2A2)
CFA: 488165(SLC2A2)
VVP: 112926672(SLC2A2)
VLG: 121477379(SLC2A2)
AML: 100475889(SLC2A2)
UMR: 103676147(SLC2A2)
UAH: 113255119(SLC2A2)
ORO: 101367009(SLC2A2)
ELK: 111150341
MPUF: 101670937(SLC2A2)
EJU: 114207055(SLC2A2)
MLX: 118000275(SLC2A2)
FCA: 100142681(SLC2A2)
PTG: 102961271(SLC2A2)
PPAD: 109275126(SLC2A2)
AJU: 106990050(SLC2A2)
HHV: 120234618(SLC2A2)
BTA: 282357(SLC2A2)
BOM: 102277237(SLC2A2)
BIU: 109558192(SLC2A2)
BBUB: 102400959(SLC2A2)
CHX: 102176460(SLC2A2)
OAS: 443205(SLC2A2)
ODA: 120869759(SLC2A2)
SSC: 397429(SLC2A2)
CFR: 102524363(SLC2A2)
CDK: 105086009(SLC2A2)
BACU: 103000646(SLC2A2)
LVE: 103086850(SLC2A2)
OOR: 101285939(SLC2A2)
DLE: 111174077(SLC2A2)
PCAD: 102984344(SLC2A2)
ECB: 100033974(SLC2A2)
EPZ: 103546363(SLC2A2)
EAI: 106847542(SLC2A2)
MYB: 102257921(SLC2A2)
MYD: 102773357(SLC2A2)
MMYO: 118677395(SLC2A2)
MNA: 107529525(SLC2A2)
HAI: 109383439(SLC2A2)
DRO: 112304870(SLC2A2)
SHON: 118987406(SLC2A2)
AJM: 119043438(SLC2A2)
MMF: 118617351(SLC2A2)
PALE: 102883555(SLC2A2)
RAY: 107501411(SLC2A2)
MJV: 108398018(SLC2A2)
TOD: 119257284(SLC2A2)
LAV: 100669209(SLC2A2)
TMU: 101356489
MDO: 100010342(SLC2A2)
SHR: 100923865(SLC2A2)
PCW: 110203994(SLC2A2)
OAA: 100086793(SLC2A2)
GGA: 396272(SLC2A2)
PCOC: 116243383(SLC2A2)
MGP: 100539563(SLC2A2)
CJO: 107318334(SLC2A2)
NMEL: 110398099(SLC2A2)
APLA: 101803907(SLC2A2)
ACYG: 106031994(SLC2A2)
TGU: 100218276(SLC2A2)
LSR: 110480353(SLC2A2)
SCAN: 103815293(SLC2A2)
PMOA: 120504366(SLC2A2)
GFR: 102038277(SLC2A2)
FAB: 101820821(SLC2A2)
PHI: 102102379(SLC2A2)
PMAJ: 107208774(SLC2A2)
CCAE: 111933593(SLC2A2)
CCW: 104688041(SLC2A2)
ETL: 114061180(SLC2A2)
FPG: 101924748(SLC2A2)
FCH: 102053009(SLC2A2)
CLV: 102090795(SLC2A2)
EGZ: 104132471(SLC2A2)
NNI: 104022055(SLC2A2)
ACUN: 113483593(SLC2A2)
PADL: 103924962(SLC2A2)
AAM: 106486598(SLC2A2)
ASN: 102372548(SLC2A2)
AMJ: 102573725(SLC2A2)
CPOO: 109308434(SLC2A2)
GGN: 109287981(SLC2A2)
PSS: 102451172
CMY: 102940285(SLC2A2)
CPIC: 101951250(SLC2A2)
TST: 117882596(SLC2A2)
CABI: 116826731(SLC2A2)
ACS: 100553701(slc2a2)
PVT: 110079055(SLC2A2)
PBI: 103063859(SLC2A2)
PMUR: 107296419(SLC2A2)
PGUT: 117678191(SLC2A2)
PMUA: 114597978(SLC2A2)
ZVI: 118093772(SLC2A2)
GJA: 107111899(SLC2A2)
XLA: 108718098(slc2a2.S) 432042(slc2a2.L)
XTR: 496943(slc2a2)
NPR: 108784826(SLC2A2)
DRE: 322493(slc2a2)
SANH: 107680265
IPU: 108278343(slc2a2)
PHYP: 113524403
AMEX: 103022443(slc2a2)
EEE: 113576487(slc2a2)
TRU: 101065501(slc2a2)
LCO: 104920046
NCC: 104958942
ELY: 117267619(slc2a2)
PLEP: 121953232(slc2a2)
SLUC: 116057458(slc2a2)
ECRA: 117936006(slc2a2)
PFLV: 114546584(slc2a2)
GAT: 120833405(slc2a2)
MSAM: 119910326(slc2a2)
CUD: 121526087(slc2a2)
MZE: 101482471(slc2a2)
ONL: 100534484
OAU: 116318068(slc2a2)
OLA: 101166670(slc2a2)
OML: 112149193(slc2a2)
XMA: 102220025(slc2a2)
XCO: 114133742(slc2a2)
XHE: 116708659(slc2a2)
PRET: 103458415(slc2a2)
CVG: 107085104(slc2a2)
CTUL: 119788182(slc2a2)
NFU: 107392074(slc2a2)
KMR: 108249199(slc2a2)
ALIM: 106534351(slc2a2)
AOCE: 111569440(slc2a2)
CSEM: 103378916(slc2a2)
POV: 109636361(slc2a2)
LCF: 108874900(slc2a2)
SDU: 111225928
SLAL: 111665821(slc2a2)
XGL: 120795143(slc2a2)
HCQ: 109517287(slc2a2)
BPEC: 110157356(slc2a2)
MALB: 109969620(slc2a2)
OTW: 112239038
ELS: 105019809
SFM: 108935126(slc2a2)
PKI: 111850509
LOC: 102694631(slc2a2)
PSPA: 121326393(slc2a2)
LCM: 102359756(SLC2A2)
CMK: 103189327(slc2a2)
RTP: 109928470
PPOT: 106108220
PXU: 106121335
 » show all
Reference
PMID:3399500
  Authors
Fukumoto H, Seino S, Imura H, Seino Y, Eddy RL, Fukushima Y, Byers MG, Shows TB, Bell GI
  Title
Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein.
  Journal
Proc Natl Acad Sci U S A 85:5434-8 (1988)
DOI:10.1073/pnas.85.15.5434
  Sequence
[hsa:6514]
Reference
  Authors
Kellett GL, Brot-Laroche E, Mace OJ, Leturque A
  Title
Sugar absorption in the intestine: the role of GLUT2.
  Journal
Annu Rev Nutr 28:35-54 (2008)
DOI:10.1146/annurev.nutr.28.061807.155518
Reference
  Authors
Zhao FQ, Keating AF
  Title
Functional properties and genomics of glucose transporters.
  Journal
Curr Genomics 8:113-28 (2007)
DOI:10.2174/138920207780368187
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