KEGG   ORTHOLOGY: K07370Help
Entry
K07370                      KO                                     

Name
BTK
Definition
Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
Pathway
ko04064  NF-kappa B signaling pathway
ko04380  Osteoclast differentiation
ko04611  Platelet activation
ko04662  B cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko05169  Epstein-Barr virus infection
ko05340  Primary immunodeficiency
Disease
H00085  Agammaglobulinemias
H00254  Growth hormone deficiency
H02035  Isolated growth hormone deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
   04662 B cell receptor signaling pathway
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
   04664 Fc epsilon RI signaling pathway
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
 09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  TEC family
   K07370  BTK; Bruton agammaglobulinemia tyrosine kinase
BRITE hierarchy
Other DBs
GO: 0004715
Genes
HSA: 695(BTK)
PTR: 465759(BTK)
PPS: 100992723(BTK)
GGO: 101141049(BTK)
PON: 100443503(BTK)
NLE: 100594539(BTK)
MCC: 703000(BTK)
MCF: 102123534(BTK)
CSAB: 103232359(BTK)
RRO: 104659579(BTK)
RBB: 108544993(BTK)
CJC: 100406337(BTK)
SBQ: 101054345(BTK)
MMU: 12229(Btk)
MCAL: 110286488(Btk)
MPAH: 110313310(Btk)
RNO: 367901(Btk)
MUN: 110541656(Btk) 110543536
CGE: 100772144(Btk)
NGI: 103746197(Btk)
HGL: 101715242(Btk)
CCAN: 109692203(Btk)
OCU: 100354225(BTK)
TUP: 102472301(BTK)
CFA: 492019(BTK)
VVP: 112925763(BTK)
AML: 100472303(BTK)
UMR: 103672987(BTK)
UAH: 113244303(BTK)
ORO: 101368233(BTK)
FCA: 101088062(BTK) 111559190
PTG: 102948492(BTK)
AJU: 106984233(BTK)
BTA: 533459(BTK)
BOM: 102284433(BTK)
BIU: 109555469(BTK)
BBUB: 102397606(BTK)
PHD: 102323728(BTK)
CHX: 102176204(BTK)
OAS: 101105725(BTK)
SSC: 100627308(BTK)
CFR: 102521853(BTK)
CDK: 105085487(BTK)
BACU: 103007481(BTK)
LVE: 103086425(BTK)
OOR: 101282522(BTK)
DLE: 111178233(BTK)
PCAD: 102991038(BTK)
ECB: 100057626(BTK)
EPZ: 103542797(BTK) 103544689
EAI: 106823084(BTK)
MYB: 102248642(BTK)
MYD: 102758552(BTK)
MNA: 107524029(BTK)
HAI: 109374529(BTK) 109391632(TIMM29)
RSS: 109437438(BTK)
DRO: 112321325(BTK)
PALE: 102878592(BTK)
RAY: 107503613(BTK)
LAV: 100670387(BTK)
TMU: 101356880
MDO: 100022891(BTK)
SHR: 100929183(BTK)
PCW: 110192312(BTK)
OAA: 100080912(BTK)
GGA: 374075(BTK)
MGP: 100540531(BTK)
CJO: 107312560(BTK)
NMEL: 110403020(BTK)
APLA: 101801225(BTK)
ACYG: 106037664(BTK)
TGU: 100219452
LSR: 110472678(BTK)
SCAN: 103824231(BTK)
GFR: 102034670(BTK)
FAB: 101820538(BTK)
PHI: 102110408(BTK)
PMAJ: 107203971(BTK)
CCAE: 111929395(BTK)
CCW: 104691647(BTK)
ETL: 114066193(BTK)
FPG: 101911050(BTK)
FCH: 102050747(BTK)
CLV: 102089403(BTK)
EGZ: 104135432(BTK)
NNI: 104015352(BTK)
ACUN: 113479932(BTK)
PADL: 103923328(BTK)
AAM: 106484985(BTK)
ASN: 102379774(BTK)
AMJ: 102562876(BTK)
PSS: 102452612(BTK)
CMY: 102945423(BTK)
CPIC: 101931069(BTK)
ACS: 100561192(btk)
PVT: 110084914(BTK)
PBI: 103065824(BTK)
PMUR: 107291582(BTK)
GJA: 107123933(BTK)
XLA: 108698274(btk.L)
XTR: 100170477(btk)
NPR: 108799566(BTK)
DRE: 568653(btk)
SANH: 107680332 107680953(btk)
IPU: 108269130(btk)
PHYP: 113542865(btk)
AMEX: 103034846(btk)
EEE: 113573405(btk)
TRU: 101073533(btk)
LCO: 104925368(btk)
NCC: 104964530(btk)
MZE: 101467854(btk)
OLA: 101168549(btk)
XMA: 102229275(btk)
XCO: 114139713(btk)
PRET: 103471526(btk)
NFU: 107377689(btk)
KMR: 108231212(btk)
AOCE: 111577298(btk)
CSEM: 103390584(btk)
POV: 109627038(btk)
LCF: 108895374(btk)
SDU: 111232725(btk)
HCQ: 109515846(btk)
BPEC: 110158863
MALB: 109956117(btk)
SASA: 100194909(btk)
OTW: 112221095(btk)
SALP: 111965886(btk)
ELS: 105025807(btk)
SFM: 108922820(btk) 108931000
PKI: 111833669(btk) 111835079
LCM: 102346267(BTK)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bradshaw JM
  Title
The Src, Syk, and Tec family kinases: distinct types of molecular switches.
  Journal
Cell Signal 22:1175-84 (2010)
DOI:10.1016/j.cellsig.2010.03.001
  Sequence
[hsa:695]
Reference
PMID:8380905
  Authors
Vetrie D, Vorechovsky I, Sideras P, Holland J, Davies A, Flinter F, Hammarstrom L, Kinnon C, Levinsky R, Bobrow M, et al.
  Title
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases.
  Journal
Nature 361:226-33 (1993)
DOI:10.1038/361226a0
  Sequence
[hsa:695]
LinkDB All DBs

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