KEGG   ORTHOLOGY: K07513
Entry
K07513                      KO                                     

Name
ACAA1
Definition
acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
Pathway
ko00071  Fatty acid degradation
ko00280  Valine, leucine and isoleucine degradation
ko00592  alpha-Linolenic acid metabolism
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04146  Peroxisome
Module
M00087  beta-Oxidation
M00113  Jasmonic acid biosynthesis
M00861  beta-Oxidation, peroxisome, VLCFA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K07513  ACAA1; acetyl-CoA acyltransferase 1
   00592 alpha-Linolenic acid metabolism
    K07513  ACAA1; acetyl-CoA acyltransferase 1
   01040 Biosynthesis of unsaturated fatty acids
    K07513  ACAA1; acetyl-CoA acyltransferase 1
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K07513  ACAA1; acetyl-CoA acyltransferase 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    K07513  ACAA1; acetyl-CoA acyltransferase 1
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K07513  ACAA1; acetyl-CoA acyltransferase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.16  acetyl-CoA C-acyltransferase
     K07513  ACAA1; acetyl-CoA acyltransferase 1
Other DBs
RN: R00238 R00927 R01177 R03778 R03858 R03991 R04546 R04742 R04747 R07891 R07895 R07899 R07937 R07953
GO: 0003988
Genes
HSA: 30(ACAA1)
PTR: 460268(ACAA1)
PPS: 100994212(ACAA1)
GGO: 101141231(ACAA1)
PON: 100461213(ACAA1)
NLE: 100597596(ACAA1)
MCC: 696743(ACAA1)
MCF: 102143849(ACAA1)
CSAB: 103221068(ACAA1)
RRO: 104657451(ACAA1)
RBB: 108512243(ACAA1)
CJC: 100412554(ACAA1)
SBQ: 101052252(ACAA1)
MMU: 113868(Acaa1a) 235674(Acaa1b)
MPAH: 110327492(Acaa1) 110328451
RNO: 24157(Acaa1a) 501072(Acaa1b)
HGL: 101713505(Acaa1) 101714191
OCU: 100340554(ACAA1)
TUP: 102470441(ACAA1)
CFA: 477023(ACAA1)
VVP: 112921659(ACAA1)
AML: 100475784(ACAA1)
UMR: 103682196(ACAA1)
UAH: 113253780(ACAA1)
ORO: 101363464(ACAA1)
ELK: 111159048
FCA: 101087343(ACAA1)
PTG: 102967023(ACAA1)
PPAD: 109248748(ACAA1)
AJU: 106966644(ACAA1)
BTA: 508324(ACAA1)
BOM: 102280228(ACAA1)
BIU: 109576258(ACAA1)
BBUB: 102396359(ACAA1)
CHX: 102184764(ACAA1)
OAS: 101110625(ACAA1)
SSC: 100515577(ACAA1)
CFR: 102506838(ACAA1)
CDK: 105090693(ACAA1)
BACU: 103013122(ACAA1)
LVE: 103088661(ACAA1)
OOR: 101278829(ACAA1)
DLE: 111164349(ACAA1)
PCAD: 102974484(ACAA1)
ECB: 100050082(ACAA1)
EPZ: 103553900(ACAA1)
EAI: 106834267(ACAA1)
MYB: 102247718(ACAA1)
MYD: 102759768(ACAA1)
MNA: 107524306
HAI: 109393490(ACAA1)
DRO: 112309850(ACAA1)
PALE: 102890231(ACAA1)
RAY: 107499599(ACAA1)
MJV: 108401028(ACAA1)
LAV: 100667518(ACAA1)
TMU: 101341576
MDO: 100021694(ACAA1)
SHR: 100932858(ACAA1)
PCW: 110192929(ACAA1)
OAA: 100090526(ACAA1)
GGA: 770094(ACAA1)
MGP: 100542533(ACAA1)
CJO: 107308790(ACAA1)
NMEL: 110394676(ACAA1)
APLA: 101797981(ACAA1)
ACYG: 106036840(ACAA1)
TGU: 100232310(ACAA1)
LSR: 110484539(ACAA1)
SCAN: 103812699(ACAA1)
GFR: 102044074(ACAA1)
FAB: 101816553(ACAA1)
PHI: 102108642(ACAA1)
PMAJ: 107200236(ACAA1)
CCAE: 111925455(ACAA1)
CCW: 104686412(ACAA1)
ETL: 114065135(ACAA1)
FPG: 101923424(ACAA1)
FCH: 102050522(ACAA1)
CLV: 102088336(ACAA1)
EGZ: 104130983(ACAA1)
NNI: 104021752(ACAA1)
ACUN: 113476335(ACAA1)
AAM: 106494846(ACAA1)
ASN: 102368605(ACAA1)
AMJ: 102562558(ACAA1)
PSS: 102455625(ACAA1)
CMY: 102932084
CPIC: 101943221(ACAA1)
ACS: 100567075(acaa1)
PVT: 110085831(ACAA1)
PBI: 103056268
PMUR: 107284371(ACAA1)
TSR: 106554068(ACAA1)
PMUA: 114606975(ACAA1)
GJA: 107107954(ACAA1)
XLA: 380296(acaa1.L)
XTR: 780143(acaa1)
NPR: 108797614(ACAA1)
DRE: 431754(acaa1)
IPU: 100528276(acaa1)
PHYP: 113541245(acaa1)
AMEX: 103044652(acaa1)
EEE: 113581209(acaa1)
TRU: 101063902(acaa1)
LCO: 104927325(acaa1)
NCC: 104959411(acaa1)
MZE: 101465882(acaa1)
ONL: 100709821(acaa1)
OLA: 101173322(acaa1)
XMA: 102223074(acaa1)
XCO: 114144298(acaa1)
PRET: 103473178(acaa1)
CVG: 107094433(acaa1)
NFU: 107394222(acaa1)
KMR: 108251775(acaa1)
ALIM: 106535425(acaa1)
AOCE: 111563089(acaa1)
CSEM: 103383387(acaa1)
LCF: 108888719(acaa1)
SDU: 111232969(acaa1)
SLAL: 111651959(acaa1)
BPEC: 110175545(acaa1)
MALB: 109971785(acaa1)
SASA: 106579756
OTW: 112235894(acaa1)
SALP: 112076835(acaa1)
ELS: 105007694(acaa1)
SFM: 108934024(acaa1)
PKI: 111837860(acaa1)
LCM: 102348225(ACAA1)
CMK: 103191285(acaa1)
RTP: 109921355(acaa1)
BFO: 118424439
APLC: 110989318
SKO: 100372855
PCAN: 112564571
CRG: 105319875
MYI: 110452917
LAK: 106157535
ATH: AT1G04710(PKT4) AT2G33150(PKT3) AT5G48880(KAT5)
VRA: 106772635
VAR: 108326422
LJA: Lj0g3v0197249.1(Lj0g3v0197249.1) Lj0g3v0197249.2(Lj0g3v0197249.2) Lj0g3v0259119.1(Lj0g3v0259119.1)
NNU: 104587903
DOSA: Os02t0817700-02(Os02g0817700) Os10t0457600-01(Os10g0457600)
ATS: 109779883(LOC109779883) 109787002(LOC109787002)
ZMA: 100192501 100193233 100274263(pco082145)
ATR: 18444168
CRE: CHLREDRAFT_138637(ATO1)
APRO: F751_5597
SCE: YIL160C(POT1)
ERC: Ecym_4003
KMX: KLMA_20220(POT1)
NDI: NDAI_0C02520(NDAI0C02520)
TPF: TPHA_0E00110(TPHA0E00110)
TBL: TBLA_0E01830(TBLA0E01830)
TDL: TDEL_0F05590(TDEL0F05590)
KAF: KAFR_0H00110(KAFR0H00110)
PIC: PICST_55180(POT13) PICST_79854(POT11)
SLB: AWJ20_1140(POT1) AWJ20_2360(POT1)
NTE: NEUTE1DRAFT68512(NEUTE1DRAFT_68512) NEUTE1DRAFT77879(NEUTE1DRAFT_77879) NEUTE1DRAFT87502(NEUTE1DRAFT_87502)
CMT: CCM_01627
ANG: ANI_1_452024(An02g03320) ANI_1_76114(An13g00590) ANI_1_770074(An08g05400) ANI_1_942184(An04g05720)
CNE: CNA04700
CNB: CNBA4520
ABP: AGABI1DRAFT112317(AGABI1DRAFT_112317) AGABI1DRAFT32206(AGABI1DRAFT_32206) AGABI1DRAFT51517(AGABI1DRAFT_51517)
ABV: AGABI2DRAFT175902(AGABI2DRAFT_175902) AGABI2DRAFT193507(AGABI2DRAFT_193507) AGABI2DRAFT239518(AGABI2DRAFT_239518)
MGL: MGL_3510
MRT: MRET_0926
SMIN: v1.2.036595.t1(symbB.v1.2.036595.t1) v1.2.036596.t1(symbB.v1.2.036596.t1) v1.2.036597.t1(symbB.v1.2.036597.t1)
PTI: PHATRDRAFT_41969(KCT1)
TPS: THAPSDRAFT_36742(KCT2)
SPAR: SPRG_04484
 » show all
Reference
PMID:9490742
  Authors
Hayashi M, Toriyama K, Kondo M, Nishimura M
  Title
2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation.
  Journal
Plant Cell 10:183-95 (1998)
DOI:10.1105/tpc.10.2.183
  Sequence
[ath:AT2G33150]
Reference
  Authors
GOLDMAN DS
  Title
Studies on the fatty acid oxidizing system of animal tissues. VII. The beta-ketoacyl coenzyme A cleavage enzyme.
  Journal
J Biol Chem 208:345-57 (1954)
Reference
  Authors
Sordillo JE, Sharma S, Poon A, Lasky-Su J, Belanger K, Milton DK, Bracken MB, Triche EW, Leaderer BP, Gold DR, Litonjua AA
  Title
Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1.
  Journal
BMC Med Genet 12:158 (2011)
DOI:10.1186/1471-2350-12-158
LinkDB

KEGG   ORTHOLOGY: K08764
Entry
K08764                      KO                                     

Name
SCP2, SCPX
Definition
sterol carrier protein 2 [EC:2.3.1.176]
Pathway
ko00120  Primary bile acid biosynthesis
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04146  Peroxisome
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
M00861  beta-Oxidation, peroxisome, VLCFA
M00862  beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Disease
H00407  Peroxisomal beta-oxidation enzyme deficiency
H00874  Leukoencephalopathy with dystonia and motor neuropathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    K08764  SCP2, SCPX; sterol carrier protein 2
   01040 Biosynthesis of unsaturated fatty acids
    K08764  SCP2, SCPX; sterol carrier protein 2
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    K08764  SCP2, SCPX; sterol carrier protein 2
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K08764  SCP2, SCPX; sterol carrier protein 2
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.176  propanoyl-CoA C-acyltransferase
     K08764  SCP2, SCPX; sterol carrier protein 2
Other DBs
RN: R03719 R04811 R07937 R07953
GO: 0033814
Genes
HSA: 6342(SCP2)
PTR: 456862(SCP2)
PPS: 100986541(SCP2)
GGO: 101143883(SCP2)
PON: 100173072(SCP2)
NLE: 100597097(SCP2)
MCC: 715765(SCP2)
MCF: 102140312(SCP2)
CSAB: 103224800(SCP2)
RRO: 104669256(SCP2)
RBB: 108531191(SCP2)
CJC: 100388218(SCP2)
SBQ: 101036680(SCP2)
MMU: 20280(Scp2)
MCAL: 110292209(Scp2)
MPAH: 110323135(Scp2)
RNO: 25541(Scp2)
MUN: 110563883(Scp2)
CGE: 100757558(Scp2)
NGI: 103730241(Scp2)
HGL: 101705283(Scp2)
CCAN: 109693360(Scp2)
OCU: 100008683(SCP2)
TUP: 102487249(SCP2)
CFA: 479564(SCP2)
VVP: 112926124(SCP2)
AML: 100469567(SCP2)
UMR: 103670702(SCP2)
UAH: 113254655(SCP2)
ORO: 101367151(SCP2)
ELK: 111143445
FCA: 101093036(SCP2)
PTG: 102951550(SCP2)
PPAD: 109266864(SCP2)
AJU: 106987886(SCP2)
BTA: 508918(SCP2)
BOM: 102281973
BIU: 109556283(SCP2)
BBUB: 102409865(SCP2)
CHX: 102182369(SCP2)
OAS: 101117285(SCP2)
SSC: 397439(SCP2)
CFR: 102516689(SCP2)
CDK: 105090773(SCP2)
BACU: 103008562(SCP2)
LVE: 103081853
OOR: 101279314(SCP2)
DLE: 111175824(SCP2)
PCAD: 102988699(SCP2)
ECB: 100061338(SCP2)
EPZ: 103558615(SCP2)
EAI: 106833182(SCP2)
MYB: 102242920(SCP2)
MYD: 102765227(SCP2)
MNA: 107535398(SCP2)
DRO: 112314454(SCP2)
PALE: 102884769(SCP2)
RAY: 107497927(SCP2)
MJV: 108403979(SCP2)
LAV: 100666078
TMU: 101347488
MDO: 100017946(SCP2)
SHR: 100922562(SCP2)
PCW: 110209359(SCP2)
OAA: 100084202(SCP2)
GGA: 396550(SCP2)
MGP: 100541979(SCP2)
CJO: 107317654(SCP2)
NMEL: 110402526(SCP2)
APLA: 101803933(SCP2)
ACYG: 106032940(SCP2)
TGU: 100218387(SCP2)
LSR: 110470146(SCP2)
SCAN: 103815029(SCP2)
GFR: 102042799(SCP2)
FAB: 101820874(SCP2)
PHI: 102105546(SCP2)
PMAJ: 107208151(SCP2)
CCAE: 111933041(SCP2)
CCW: 104695523(SCP2)
ETL: 114062766(SCP2)
FPG: 101913645(SCP2)
FCH: 102053527(SCP2)
CLV: 102087499(SCP2)
EGZ: 104131500(SCP2)
ACUN: 113483071(SCP2)
PADL: 103913664(SCP2)
AAM: 106491062(SCP2)
AMJ: 102570791(SCP2)
PSS: 102461487(SCP2)
CMY: 102931842
CPIC: 101937963(SCP2)
ACS: 100559527(scp2)
PVT: 110082239(SCP2)
PBI: 103053379(SCP2)
PMUR: 107283044(SCP2)
TSR: 106546053(SCP2)
PMUA: 114598987(SCP2)
GJA: 107120559(SCP2)
XLA: 108715604 494715(scp2.L)
XTR: 548512(scp2)
NPR: 108783818(SCP2)
DRE: 393839(scp2a)
SRX: 107719264(scp2) 107722381
SANH: 107681719(scp2)
SGH: 107593851(scp2)
CCAR: 109091477
IPU: 108267621(scp2)
PHYP: 113540595
AMEX: 103022159(scp2)
EEE: 113570128(scp2)
TRU: 101069006(scp2)
LCO: 104936979(scp2)
NCC: 104949681(scp2)
MZE: 101481799(scp2)
ONL: 100711328
OLA: 101175107(scp2)
XMA: 102226285
XCO: 114145905(scp2)
PRET: 103479011(scp2)
CVG: 107083609(scp2)
NFU: 107384403
KMR: 108238206(scp2)
ALIM: 106527182(scp2)
AOCE: 111587618(scp2)
CSEM: 103395834(scp2)
POV: 109646608(scp2)
LCF: 108883814(scp2)
SDU: 111228861(scp2)
SLAL: 111670554(scp2)
HCQ: 109521343(scp2)
BPEC: 110173449(scp2) 110173461
MALB: 109970643(scp2)
SASA: 106569705(scp2)
OTW: 112260891(scp2)
SALP: 112069550
ELS: 105022798(scp2)
SFM: 108935159(scp2)
PKI: 111847545(scp2)
LCM: 102354489
CMK: 103185291(scp2)
RTP: 109913670(scp2)
BFO: 118431877
APLC: 110986063
SKO: 100368127(SCP2) 100368276
DME: Dmel_CG17320(ScpX) Dmel_CG17597(CG17597)
DSI: Dsimw501_GD21807(Dsim_GD21807)
MDE: 101899830
LCQ: 111680181
AAG: 5575668
AME: 408904
BIM: 100748275
BTER: 100647066
CCAL: 108628439
OBB: 114870987
SOC: 105201416
MPHA: 105840706
AEC: 105153563
ACEP: 105618569
PBAR: 105432859
VEM: 105559618
HST: 105189995
DQU: 106742407
CFO: 105251216
LHU: 105675589
PGC: 109861339
OBO: 105274767
PCF: 106788866
NVI: 100123951
CSOL: 105363609
MDL: 103571215
TCA: 657233(Scpx)
DPA: 109539789
ATD: 109602926
NVL: 108556749
BMOR: 692782(Scpx)
BMAN: 114242327
PRAP: 110993930
HAW: 110373174
TNL: 113497353
PXY: 105382506
API: 100161454
DNX: 107161308
AGS: 114122268
RMD: 113555937
BTAB: 109035142
CLEC: 106670708
ZNE: 110831910
FCD: 110850871
PVM: 113823286
TUT: 107367461
CSCU: 111639045
CEL: CELE_Y57A10C.6(daf-22)
CBR: CBG20965
BMY: Bm1_53275
MYI: 110461537
OBI: 106877352
AMIL: 114970597
DGT: 114526215
AQU: 100638133
NCR: NCU03372
NTE: NEUTE1DRAFT84532(NEUTE1DRAFT_84532)
MGR: MGG_02409
SSCK: SPSK_02507
MAW: MAC_03561
MAJ: MAA_02626
MBE: MBM_04974
ANG: ANI_1_216184(An04g00740)
PBL: PAAG_11860(PAAG_04374)
ABE: ARB_01676
TVE: TRV_00032
PTE: PTT_11137
TASA: A1Q1_03740
ABP: AGABI1DRAFT110046(AGABI1DRAFT_110046)
ABV: AGABI2DRAFT190063(AGABI2DRAFT_190063)
SFR: Sfri_0743
CPS: CPS_0669
PSEO: OM33_12585
PSPO: PSPO_a2037
ADI: B5T_02065
APAC: S7S_16300
AXE: P40_09880
GPB: HDN1F_17110(tioL)
AAA: Acav_2987
HPSE: HPF_13290(paaJ2)
EBA: ebA306(tioL) ebA5797
TCL: Tchl_1577
PLA: Plav_0155
BRS: S23_06920
RPB: RPB_4078
RPD: RPD_3814
XAU: Xaut_4071
CAK: Caul_0450
SPSE: SULPSESMR1_04594(fadA)
SWI: Swit_4119
SMIC: SmB9_09260
AZL: AZL_a11110(fadA)
TMO: TMO_0975
MJL: Mjls_1512
MVQ: MYVA_4960
MCHT: MCHIJ_01810(ltp1_1)
ASD: AS9A_0934
NSR: NS506_04193(scp2)
GOR: KTR9_3195
 » show all
Reference
  Authors
Russell DW
  Title
The enzymes, regulation, and genetics of bile acid synthesis.
  Journal
Annu Rev Biochem 72:137-74 (2003)
DOI:10.1146/annurev.biochem.72.121801.161712
Reference
  Authors
Stanley WA, Filipp FV, Kursula P, Schuller N, Erdmann R, Schliebs W, Sattler M, Wilmanns M
  Title
Recognition of a functional peroxisome type 1 target by the dynamic import receptor pex5p.
  Journal
Mol Cell 24:653-63 (2006)
DOI:10.1016/j.molcel.2006.10.024
  Sequence
[hsa:6342]
Reference
  Authors
Ferdinandusse S, Denis S, Mooijer PA, Zhang Z, Reddy JK, Spector AA, Wanders RJ
  Title
Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid.
  Journal
J Lipid Res 42:1987-95 (2001)
LinkDB

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