KEGG   ORTHOLOGY: K08524Help
Entry
K08524                      KO                                     

Name
RXRA, NR2B1
Definition
retinoid X receptor alpha
Pathway
ko03320  PPAR signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04659  Th17 cell differentiation
ko04919  Thyroid hormone signaling pathway
ko04920  Adipocytokine signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04976  Bile secretion
ko05160  Hepatitis C
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05216  Thyroid cancer
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   03320 PPAR signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   04919 Thyroid hormone signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   04928 Parathyroid hormone synthesis, secretion and action
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09154 Digestive system
   04976 Bile secretion
    K08524  RXRA, NR2B1; retinoid X receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05202 Transcriptional misregulation in cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09162 Cancer: specific types
   05226 Gastric cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05216 Thyroid cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05222 Small cell lung cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05223 Non-small cell lung cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09172 Infectious disease: viral
   05160 Hepatitis C
    K08524  RXRA, NR2B1; retinoid X receptor alpha
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08524  RXRA, NR2B1; retinoid X receptor alpha
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    K08524  RXRA, NR2B1; retinoid X receptor alpha
Nuclear receptors [BR:ko03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   K08524  RXRA, NR2B1; retinoid X receptor alpha
BRITE hierarchy
Other DBs
GO: 0004886
Genes
HSA: 6256(RXRA)
PTR: 464834(RXRA)
PPS: 100989625(RXRA)
GGO: 101128749(RXRA)
NLE: 100585339(RXRA)
MCC: 722068(RXRA)
MCF: 102133330(RXRA)
CSAB: 103239669(RXRA)
RRO: 104669710(RXRA)
RBB: 108513168(RXRA)
CJC: 100407498(RXRA)
SBQ: 101044148(RXRA)
MMU: 20181(Rxra)
MCAL: 110308122(Rxra)
MPAH: 110317492(Rxra)
RNO: 25271(Rxra)
MUN: 110549176(Rxra)
CGE: 100768377(Rxra)
NGI: 103742823(Rxra)
HGL: 101723948(Rxra)
CCAN: 109695052(Rxra)
TUP: 102470277(RXRA)
CFA: 491278(RXRA)
VVP: 112906873(RXRA)
AML: 100479839(RXRA)
UMR: 103679944(RXRA)
UAH: 113266584(RXRA)
ORO: 101365135(RXRA)
ELK: 111146039
FCA: 101085757(RXRA)
PPAD: 109258269(RXRA)
AJU: 106988254(RXRA)
BTA: 507554(RXRA)
BOM: 102265047(RXRA)
BIU: 109566619(RXRA)
BBUB: 102404333(RXRA)
CHX: 108634606
OAS: 114113852(RXRA)
SSC: 397306(RXRA)
CFR: 102518674(RXRA)
CDK: 105106306(RXRA)
BACU: 103005517(RXRA)
LVE: 103083851(RXRA)
OOR: 101270600(RXRA)
DLE: 111177070(RXRA)
PCAD: 102992401(RXRA)
ECB: 100069096(RXRA)
EPZ: 103542697(RXRA)
EAI: 106845341(RXRA)
MYB: 102262918(RXRA)
MYD: 102762226(RXRA)
MNA: 107524613(RXRA)
HAI: 109381229(RXRA)
DRO: 112306469(RXRA)
PALE: 102881572(RXRA)
RAY: 107502027(RXRA)
MJV: 108399547(RXRA)
LAV: 100674208
TMU: 101353449
MDO: 100019466(RXRA)
SHR: 100926708(RXRA)
PCW: 110205364(RXRA)
GGA: 417143(RXRA)
MGP: 100545391(RXRA)
CJO: 107321878(RXRA)
NMEL: 110406787(RXRA)
APLA: 101794030(RXRA)
ACYG: 106044107(RXRA)
TGU: 100231066(RXRA)
LSR: 110477629(RXRA)
SCAN: 103818959(RXRA)
GFR: 102037605(RXRA)
FAB: 101807658(RXRA)
PHI: 102099900(RXRA)
PMAJ: 107212084(RXRA)
CCAE: 111937054(RXRA)
CCW: 104688345(RXRA)
ETL: 114059088(RXRA)
FPG: 101923856(RXRA)
FCH: 102047863(RXRA)
CLV: 102098621(RXRA)
EGZ: 104129339(RXRA)
NNI: 104023200(RXRA)
ACUN: 113486536(RXRA)
PADL: 103915261(RXRA)
AAM: 106495473(RXRA)
ASN: 102384957(RXRA)
AMJ: 102567277(RXRA)
PSS: 102443949(RXRA)
CMY: 102934777(RXRA)
CPIC: 101935365(RXRA)
ACS: 100561503(rxra)
PVT: 110089296(RXRA)
PBI: 103051303
PMUR: 107292619
TSR: 106549135(RXRA)
PMUA: 114588779(RXRA)
GJA: 107115577(RXRA)
XLA: 108699915 378685(rxra.L)
XTR: 100487877(rxra)
NPR: 108795632(RXRA)
DRE: 30464(rxrga) 555578(rxraa)
TRU: 101062011(rxra) 101064914
LCO: 104922748 104924865(rxra)
NCC: 104965568
MZE: 101473356(rxra)
ONL: 100707695(rxra)
OLA: 100125504(rxra) 100125506
XMA: 102218909 102234004(rxra)
XCO: 114140512 114149501(rxra)
PRET: 103474009(rxra)
CVG: 107102339(rxra)
NFU: 107396340(rxra)
KMR: 108241374(rxra)
ALIM: 106513573(rxra)
CSEM: 103388487 103389488(rxra)
LCF: 108880296(rxra) 108891119
SDU: 111237507(rxra) 111238777
SLAL: 111655951(rxra)
SFM: 108927205 108938562(rxra)
LCM: 102345799(RXRA) 102351060
CMK: 103184713(rxra) 103184778
CIN: 778746(rxr)
SPU: 579018
APLC: 110976278
SKO: 100329058
API: 100164958(Usp)
DNX: 107165733
AGS: 114130882
RMD: 113559425
BTAB: 109032681
CLEC: 106665686
ZNE: 110832159
TUT: 107365491
CSCU: 111641197
BMY: Bm1_14835
PCAN: 112574661
MYI: 110463383
OBI: 106868437
LAK: 106175291
SHX: MS3_01783
ADF: 107337288
DGT: 114519180
HMG: 101235557
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2159111
  Authors
Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM
  Title
Nuclear receptor that identifies a novel retinoic acid response pathway.
  Journal
Nature 345:224-9 (1990)
DOI:10.1038/345224a0
  Sequence
[hsa:6256]
Reference
  Authors
Lefebvre P, Benomar Y, Staels B
  Title
Retinoid X receptors: common heterodimerization partners with distinct functions.
  Journal
Trends Endocrinol Metab 21:676-83 (2010)
DOI:10.1016/j.tem.2010.06.009
LinkDB All DBs

KEGG   ORTHOLOGY: K08525Help
Entry
K08525                      KO                                     

Name
RXRB, NR2B2
Definition
retinoid X receptor beta
Pathway
ko03320  PPAR signaling pathway
ko04659  Th17 cell differentiation
ko04919  Thyroid hormone signaling pathway
ko04920  Adipocytokine signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05216  Thyroid cancer
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   03320 PPAR signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   04919 Thyroid hormone signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   04928 Parathyroid hormone synthesis, secretion and action
    K08525  RXRB, NR2B2; retinoid X receptor beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05202 Transcriptional misregulation in cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09162 Cancer: specific types
   05226 Gastric cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05216 Thyroid cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05222 Small cell lung cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05223 Non-small cell lung cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08525  RXRB, NR2B2; retinoid X receptor beta
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08525  RXRB, NR2B2; retinoid X receptor beta
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    K08525  RXRB, NR2B2; retinoid X receptor beta
Nuclear receptors [BR:ko03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   K08525  RXRB, NR2B2; retinoid X receptor beta
BRITE hierarchy
Other DBs
GO: 0004886
Genes
HSA: 6257(RXRB)
PTR: 462601(RXRB)
PPS: 100992933(RXRB)
GGO: 101143109(RXRB)
PON: 100460920(RXRB)
NLE: 100580742(RXRB)
MCC: 717368(RXRB)
MCF: 102132522(RXRB)
CSAB: 103221675(RXRB)
RRO: 104657982(RXRB)
RBB: 108540287(RXRB)
CJC: 100414004(RXRB)
SBQ: 101040304(RXRB)
MMU: 20182(Rxrb)
MCAL: 110312146(Rxrb)
MPAH: 110335436(Rxrb)
RNO: 361801(Rxrb)
MUN: 110543383(Rxrb)
CGE: 100759059(Rxrb)
NGI: 103739713(Rxrb)
HGL: 101723696(Rxrb)
CCAN: 109686703(Rxrb)
OCU: 100354287(RXRB)
TUP: 102495243(RXRB)
CFA: 481735(RXRB)
VVP: 112913873(RXRB)
AML: 100475696(RXRB)
UMR: 103665560(RXRB)
UAH: 113243791(RXRB)
ORO: 101373938(RXRB)
ELK: 111152195
PTG: 102952674(RXRB)
PPAD: 109271425(RXRB)
AJU: 106976118(RXRB)
BTA: 504943(RXRB)
BOM: 102286075(RXRB)
BIU: 109576548(RXRB)
BBUB: 102408491(RXRB)
CHX: 102189445(RXRB)
OAS: 101110798(RXRB)
SSC: 100156801(RXRB)
CFR: 102517692(RXRB)
CDK: 105101393(RXRB)
BACU: 103006710(RXRB)
LVE: 103087387(RXRB)
OOR: 101287304(RXRB)
DLE: 111178670(RXRB)
PCAD: 102973179(RXRB)
ECB: 100061303(RXRB)
EPZ: 103541179(RXRB)
EAI: 106834605(RXRB)
MYB: 102247746(RXRB)
MYD: 102766946(RXRB)
MNA: 107542678(RXRB)
HAI: 109392460(RXRB)
DRO: 112302171(RXRB)
PALE: 102888877(RXRB)
RAY: 107511984(RXRB)
MJV: 108396293(RXRB)
LAV: 100662699(RXRB)
TMU: 101349083
MDO: 100027006(RXRB)
SHR: 100914649(RXRB)
PCW: 110199336(RXRB)
LSR: 110480012(RXRB)
ETL: 114072199
ASN: 102369321(RXRB)
AMJ: 102561414(RXRB)
CMY: 102930075
CPIC: 101936256(RXRB)
ACS: 100554139
PVT: 110091139(RXRB)
PBI: 103055088(RXRB)
TSR: 106553505
PMUA: 114592592(RXRB)
GJA: 107109601(RXRB)
XLA: 394278(rxrb.L) 398075(rxrb.S)
XTR: 548691(rxrb)
NPR: 108788389(RXRB)
DRE: 30530(rxrba)
SGH: 107566635
IPU: 108272672
PHYP: 113535174
AMEX: 103021434
EEE: 113591253
TRU: 101065480
LCO: 104933394
NCC: 104957485(rxrb)
MZE: 101473908
ONL: 100534499
OLA: 100125505
XMA: 102217951
XCO: 114156477
PRET: 103472931
NFU: 107378676 107394848(rxrb)
ALIM: 106517732 106519580(rxrb)
AOCE: 111584592
CSEM: 103393870
POV: 109641308
LCF: 108886934
SDU: 111239434
SLAL: 111661213
HCQ: 109514591
BPEC: 110173337
MALB: 109952506
SASA: 106569952 106588394(RXRB)
ELS: 105005656(rxrb) 105018834
SFM: 108935649(rxrb)
PKI: 111835653
LCM: 102350929
NVE: 5511614
AQU: 100616090
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1310259
  Authors
Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Garnier JM, Mader S, et al.
  Title
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.
  Journal
Cell 68:377-95 (1992)
DOI:10.1016/0092-8674(92)90478-U
  Sequence
[hsa:6257]
Reference
  Authors
Lefebvre P, Benomar Y, Staels B
  Title
Retinoid X receptors: common heterodimerization partners with distinct functions.
  Journal
Trends Endocrinol Metab 21:676-83 (2010)
DOI:10.1016/j.tem.2010.06.009
LinkDB All DBs

KEGG   ORTHOLOGY: K08526Help
Entry
K08526                      KO                                     

Name
RXRG, NR2B3
Definition
retinoid X receptor gamma
Pathway
ko03320  PPAR signaling pathway
ko04659  Th17 cell differentiation
ko04919  Thyroid hormone signaling pathway
ko04920  Adipocytokine signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05216  Thyroid cancer
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K08526  RXRG, NR2B3; retinoid X receptor gamma
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   03320 PPAR signaling pathway
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   04919 Thyroid hormone signaling pathway
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   04928 Parathyroid hormone synthesis, secretion and action
    K08526  RXRG, NR2B3; retinoid X receptor gamma
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   05202 Transcriptional misregulation in cancer
    K08526  RXRG, NR2B3; retinoid X receptor gamma
  09162 Cancer: specific types
   05226 Gastric cancer
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   05216 Thyroid cancer
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   05222 Small cell lung cancer
    K08526  RXRG, NR2B3; retinoid X receptor gamma
   05223 Non-small cell lung cancer
    K08526  RXRG, NR2B3; retinoid X receptor gamma
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08526  RXRG, NR2B3; retinoid X receptor gamma
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08526  RXRG, NR2B3; retinoid X receptor gamma
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    K08526  RXRG, NR2B3; retinoid X receptor gamma
Nuclear receptors [BR:ko03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   K08526  RXRG, NR2B3; retinoid X receptor gamma
BRITE hierarchy
Other DBs
GO: 0004886
Genes
HSA: 6258(RXRG)
PTR: 457476(RXRG)
PPS: 100992346(RXRG)
GGO: 101152695(RXRG)
PON: 100171682(RXRG)
NLE: 100592610(RXRG)
MCC: 694807(RXRG)
MCF: 101864810(RXRG)
CSAB: 103230690(RXRG)
RRO: 104670175(RXRG)
RBB: 108538378(RXRG)
CJC: 100386851(RXRG)
SBQ: 101040247(RXRG)
MMU: 20183(Rxrg)
MCAL: 110290588(Rxrg)
MPAH: 110321286(Rxrg)
RNO: 83574(Rxrg)
MUN: 110551800(Rxrg)
CGE: 100759819(Rxrg)
NGI: 103746119(Rxrg)
HGL: 101716819(Rxrg)
CCAN: 109693624(Rxrg)
TUP: 102478064(RXRG)
CFA: 478989(RXRG)
VVP: 112914313(RXRG)
AML: 100475450(RXRG)
UMR: 103658229(RXRG)
UAH: 113268688(RXRG)
ORO: 101363350(RXRG)
ELK: 111151020
FCA: 101081273(RXRG)
PTG: 102969338(RXRG)
PPAD: 109276632(RXRG)
AJU: 106965571(RXRG)
BTA: 509500(RXRG)
BOM: 102276427(RXRG)
BIU: 109577828(RXRG)
BBUB: 102401292(RXRG)
CHX: 102170009(RXRG)
OAS: 101111845(RXRG)
SSC: 445465(RXRG)
CFR: 102517333(RXRG)
CDK: 105092711(RXRG)
BACU: 103017600(RXRG)
LVE: 103081591(RXRG)
OOR: 101289285(RXRG)
DLE: 111169246(RXRG)
PCAD: 102980836(RXRG)
ECB: 100060371(RXRG)
EPZ: 103547339(RXRG)
EAI: 106831132(RXRG)
MYB: 102253053(RXRG)
MYD: 102765652(RXRG)
MNA: 107537950(RXRG)
DRO: 112322188(RXRG)
PALE: 102897820(RXRG)
RAY: 107512732(RXRG)
MJV: 108402724(RXRG)
LAV: 100653765(RXRG)
TMU: 101357073
MDO: 100016615(RXRG)
SHR: 100932014(RXRG)
PCW: 110209882(RXRG)
OAA: 114817203(RXRG)
GGA: 396231(RXRG)
MGP: 100549220(RXRG)
CJO: 107317299(RXRG)
NMEL: 110402861(RXRG)
APLA: 101793671(RXRG)
ACYG: 106041601(RXRG)
TGU: 100224780(RXRG)
LSR: 110478901(RXRG)
SCAN: 103823376(RXRG)
GFR: 102041237(RXRG)
FAB: 101809407(RXRG)
PHI: 102114310(RXRG)
PMAJ: 107207856(RXRG)
CCAE: 111932641(RXRG)
CCW: 104695611(RXRG)
ETL: 114063559(RXRG)
FPG: 101920441(RXRG)
FCH: 102058029(RXRG)
CLV: 102086198(RXRG)
EGZ: 104132058(RXRG)
NNI: 104010389(RXRG)
ACUN: 113482783(RXRG)
PADL: 103914015(RXRG)
AAM: 106493847(RXRG)
ASN: 102368843(RXRG)
AMJ: 102568642(RXRG)
PSS: 102447903(RXRG)
CMY: 102934407(RXRG)
CPIC: 101947627(RXRG)
PVT: 110090929(RXRG)
PBI: 103049602(RXRG)
PMUR: 107292556(RXRG)
PMUA: 114598410(RXRG)
GJA: 107106115(RXRG)
XLA: 496325(rxrg.L) 734648
XTR: 779621(rxrg)
DRE: 436617(rxrgb)
IPU: 108257822
PHYP: 113546821
AMEX: 103038456
TRU: 101079168
LCO: 104918458
MZE: 101470618
ONL: 100706800
OLA: 100125533
XMA: 102222228
XCO: 114150300
PRET: 103463575
CVG: 107098566
NFU: 107393220
KMR: 108230807
ALIM: 106513904
AOCE: 111573410
CSEM: 103397978
POV: 109625869
LCF: 108877415
SDU: 111232127
SLAL: 111656331
HCQ: 109532369
BPEC: 110167828
MALB: 109964059
SASA: 106560629
OTW: 112259583
ELS: 105009444
SFM: 108935541
PKI: 111841039
SKO: 100313551(Nr2)
CBR: CBG01180
OBI: 106871286
EPA: 110254871
ADF: 107344665
AMIL: 114976075
SPIS: 111329249
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1310259
  Authors
Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Garnier JM, Mader S, et al.
  Title
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.
  Journal
Cell 68:377-95 (1992)
DOI:10.1016/0092-8674(92)90478-U
  Sequence
[hsa:6258]
Reference
  Authors
Lefebvre P, Benomar Y, Staels B
  Title
Retinoid X receptors: common heterodimerization partners with distinct functions.
  Journal
Trends Endocrinol Metab 21:676-83 (2010)
DOI:10.1016/j.tem.2010.06.009
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