KEGG   ORTHOLOGY: K08731
Entry
K08731                      KO                                     

Name
BIRC5
Definition
baculoviral IAP repeat-containing protein 5
Pathway
ko01524  Platinum drug resistance
ko04210  Apoptosis
ko04215  Apoptosis - multiple species
ko04390  Hippo signaling pathway
ko05161  Hepatitis B
ko05200  Pathways in cancer
ko05210  Colorectal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
   04215 Apoptosis - multiple species
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
  09162 Cancer: specific types
   05210 Colorectal cancer
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
  09172 Infectious disease: viral
   05161 Hepatitis B
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I32: IAP family
   K08731  BIRC5; baculoviral IAP repeat-containing protein 5
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Kinetochore proteins
    CPC (chromosomal passenger complex)
     K08731  BIRC5; baculoviral IAP repeat-containing protein 5
  Centrosome formation and ciliogenesis proteins
   Other centriole associated proteins
    K08731  BIRC5; baculoviral IAP repeat-containing protein 5
Other DBs
GO: 0043027
Genes
HSA: 332(BIRC5)
PTR: 455276(BIRC5)
PPS: 100980532(BIRC5)
GGO: 101152864(BIRC5)
PON: 100172652(BIRC5)
NLE: 100598415(BIRC5)
MCC: 709565(BIRC5)
MCF: 102120307(BIRC5)
CSAB: 103243654(BIRC5)
RRO: 104659300(BIRC5)
RBB: 108534183(BIRC5)
CJC: 100398121(BIRC5)
SBQ: 101046847(BIRC5)
MMU: 11799(Birc5)
MCAL: 110305684(Birc5)
MPAH: 110332414(Birc5)
RNO: 64041(Birc5)
MUN: 110550569(Birc5)
CGE: 100769162 118237651(Birc5)
NGI: 103747285(Birc5)
HGL: 101703201(Birc5)
CCAN: 109683144(Birc5)
OCU: 103346801(BIRC5)
TUP: 102487370(BIRC5)
CFA: 442936(BIRC5)
VVP: 112920853(BIRC5)
AML: 100475314(BIRC5)
UMR: 103665963(BIRC5)
UAH: 113244569(BIRC5)
ORO: 101363894(BIRC5)
ELK: 111160341
FCA: 493835(BIRC5)
PTG: 102950505(BIRC5)
PPAD: 109276862(BIRC5)
AJU: 106981916(BIRC5)
BTA: 414925(BIRC5)
BOM: 102275014(BIRC5)
BIU: 109574440(BIRC5)
BBUB: 102396201(BIRC5)
CHX: 102180077(BIRC5)
OAS: 101123390(BIRC5)
SSC: 397266(BIRC5)
CFR: 102511273(BIRC5)
CDK: 105092156(BIRC5)
BACU: 103012250(BIRC5)
LVE: 103072055(BIRC5)
OOR: 101284595(BIRC5)
DLE: 111182765(BIRC5)
PCAD: 102977574(BIRC5)
ECB: 100050808(BIRC5)
EPZ: 103554048(BIRC5)
EAI: 106845247(BIRC5)
MYD: 102765549 102766681(BIRC5)
MNA: 107532046(BIRC5)
HAI: 109383622(BIRC5)
DRO: 112298801(BIRC5) 112302993
PALE: 102888083(BIRC5)
RAY: 107510062(BIRC5)
MJV: 108407801(BIRC5)
LAV: 100671026(BIRC5)
TMU: 101348672
MDO: 100031079(BIRC5)
SHR: 100934619(BIRC5)
PCW: 110193934(BIRC5)
OAA: 100087013(BIRC5)
GGA: 374078(BIRC5) 768589
MGP: 104911642(BIRC5)
CJO: 107310923(BIRC5) 107316337
NMEL: 110395353(BIRC5) 110400323
APLA: 106017805 113843115(BIRC5)
TGU: 100229685 100232531(BIRC5)
GFR: 102034875(BIRC5)
FAB: 101808801 101810543(BIRC5)
CCW: 104693747(BIRC5)
FPG: 101915727(BIRC5)
FCH: 102049312(BIRC5) 114016184
CLV: 102092273 102095218(BIRC5)
AAM: 106492420 106494127(BIRC5)
ASN: 102380435(BIRC5) 106722454
AMJ: 102573002(BIRC5) 106737667(BIRC5B)
CPIC: 101941733(BIRC5) 101942470
ACS: 100561388 100566215(birc5)
PVT: 110087327 110090465(BIRC5)
PBI: 103064357(BIRC5)
PMUR: 107290052(BIRC5) 107291928
TSR: 106547391(BIRC5)
PMUA: 114585314 114589289(BIRC5)
GJA: 107115319(BIRC5) 107117947
XLA: 394382(birc5.1.L) 398389 398418(birc5.1.S) 398454(birc5.2.L) 735055(birc5.2.S)
XTR: 733532(birc5) 733575(birc5l)
DRE: 246726(birc5b) 373110(birc5a)
CSEM: 103382361 103385084(survivin)
SASA: 106572692 106610005(birc5)
OTW: 112216626 112259586(birc5)
SALP: 111966102 111978782(birc5)
SFM: 108924792(birc5) 108939213
PKI: 111848326(birc5) 111853929
LCM: 102346472 102348297(BIRC5)
CMK: 103175557(birc5)
RTP: 109938723(birc5)
BFO: 118407847
CIN: 101243347
SPU: 591555
APLC: 110973714
SKO: 100374010
DME: Dmel_CG12265(Det)
DER: 6552326
DSE: 6616779
DSI: Dsimw501_GD19147(Dsim_GD19147)
DSR: 110187638
DPE: 6588227
DMN: 108156367
DWI: 6646903
DAZ: 108621898
DNV: 108651370
DHE: 111601475
DVI: 6630494
MDE: 101900208
LCQ: 111690402
AGA: AgaP_AGAP008420(IAP5)
AAG: 5563944
AME: 409405
BIM: 100748174
BTER: 100647478
CCAL: 108627732
OBB: 114879687
SOC: 105197613
MPHA: 105841090
PBAR: 105427575
VEM: 105559302
HST: 105190939
DQU: 106748600
CFO: 105252410
LHU: 105669949
PGC: 109852220
OBO: 105276140
PCF: 106793427
NVI: 100124026
CSOL: 105361290
MDL: 103575329
TCA: 100141706
DPA: 109544797
ATD: 109595544
NVL: 108564100
BMOR: 100302609(Iap2)
BMAN: 114248076
PMAC: 106713782
PRAP: 110992099
HAW: 110378778
TNL: 113494845
PXY: 105392872
API: 100159292(Det) 100569400
DNX: 107168615
AGS: 114119937
RMD: 113554160
BTAB: 109040487
CLEC: 106664242
ZNE: 110828698
FCD: 110848893
PVM: 113828653
TUT: 107362417
DPTE: 113789303
CSCU: 111623361
PTEP: 107440337
CEL: CELE_C50B8.2(bir-2) CELE_T27F2.3(bir-1)
CBR: CBG11537(Cbr-bir-2) CBG23296(Cbr-bir-1)
BMY: Bm1_06425
TSP: Tsp_10804
CRG: 105334034
MYI: 110460675
OBI: 106869909
LAK: 106155206
SHX: MS3_05833
EGL: EGR_00876
NVE: 5503801
EPA: 110250175
ADF: 107350075
AMIL: 114958296
PDAM: 113680087
SPIS: 111333255
DGT: 114529954
HMG: 101239010
 » show all
Reference
  Authors
Fangusaro JR, Caldas H, Jiang Y, Altura RA
  Title
Survivin: an inhibitor of apoptosis in pediatric cancer.
  Journal
Pediatr Blood Cancer 47:4-13 (2006)
DOI:10.1002/pbc.20805
Reference
PMID:9256286
  Authors
Ambrosini G, Adida C, Altieri DC
  Title
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma.
  Journal
Nat Med 3:917-21 (1997)
DOI:10.1038/nm0897-917
  Sequence
[hsa:332]
LinkDB

KEGG   ORTHOLOGY: K10586
Entry
K10586                      KO                                     

Name
BIRC6, BRUCE
Definition
baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
Pathway
ko04120  Ubiquitin mediated proteolysis
ko04214  Apoptosis - fly
ko04215  Apoptosis - multiple species
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
 09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
   04215 Apoptosis - multiple species
    K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.23  E2 ubiquitin-conjugating enzyme
     K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I32: IAP family
   K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
Ubiquitin system [BR:ko04121]
 Ubiquitin-conjugating enzymes (E2)
  Ubiquitin-conjugating enzymes
   K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon)
Other DBs
GO: 0043027
Genes
HSA: 57448(BIRC6)
PTR: 459138(BIRC6)
PPS: 100975802(BIRC6)
GGO: 101147286(BIRC6)
PON: 100448259(BIRC6)
NLE: 100601939(BIRC6)
MCC: 709443(BIRC6)
MCF: 102140795(BIRC6)
CSAB: 103220526(BIRC6)
RRO: 104669445(BIRC6)
RBB: 108528684(BIRC6)
CJC: 100406149(BIRC6)
SBQ: 101044261(BIRC6)
MMU: 12211(Birc6)
MCAL: 110312483(Birc6)
MPAH: 110335497(Birc6)
RNO: 313876(Birc6)
CGE: 100689237(Birc6)
NGI: 103746755(Birc6)
HGL: 101704045(Birc6)
CCAN: 109697198(Birc6)
OCU: 100342432(BIRC6)
TUP: 102473705(BIRC6)
CFA: 475718(BIRC6)
VVP: 112933011(BIRC6)
AML: 100484115(BIRC6)
UMR: 103671900(BIRC6)
UAH: 113241023(BIRC6)
ORO: 101373264(BIRC6)
ELK: 111154155
FCA: 101087396(BIRC6)
PTG: 102952639(BIRC6)
PPAD: 109266097(BIRC6)
AJU: 106967931(BIRC6)
BTA: 534211(BIRC6)
BOM: 102268689(BIRC6)
BIU: 109565520(BIRC6)
BBUB: 102406486(BIRC6)
CHX: 102189592(BIRC6)
OAS: 101103635(BIRC6)
SSC: 100049694(BIRC6)
CFR: 102504932(BIRC6)
CDK: 105095609(BIRC6)
BACU: 102999046(BIRC6)
LVE: 103072550(BIRC6)
OOR: 101287884(BIRC6)
DLE: 111174900(BIRC6)
PCAD: 102980704(BIRC6)
ECB: 100070568(BIRC6)
EPZ: 103562047(BIRC6)
EAI: 106839892(BIRC6)
MYB: 102240528(BIRC6)
MYD: 102754641(BIRC6)
MNA: 107541792(BIRC6)
HAI: 109388784(BIRC6)
DRO: 112297819(BIRC6)
PALE: 102887070(BIRC6)
RAY: 107505747(BIRC6)
MJV: 108395582(BIRC6)
LAV: 100674455(BIRC6)
TMU: 101346617
MDO: 100027051(BIRC6)
SHR: 100915294(BIRC6)
PCW: 110198157(BIRC6)
OAA: 100079899(BIRC6)
GGA: 421463(BIRC6)
MGP: 100542265(BIRC6)
CJO: 107311278(BIRC6)
NMEL: 110396654(BIRC6)
APLA: 101791861(BIRC6)
ACYG: 106029549(BIRC6)
TGU: 100225419(BIRC6)
LSR: 110480419(BIRC6)
SCAN: 103817527(BIRC6)
GFR: 102040419(BIRC6)
FAB: 101809247(BIRC6)
PHI: 102112753(BIRC6)
PMAJ: 107201726(BIRC6)
CCAE: 111927090(BIRC6)
CCW: 104684369(BIRC6)
ETL: 114065177(BIRC6)
FPG: 101911521(BIRC6)
FCH: 102048946(BIRC6)
CLV: 102090283(BIRC6)
EGZ: 104124129(BIRC6)
NNI: 104018677(BIRC6)
ACUN: 113477918(BIRC6)
PADL: 103922846(BIRC6)
AAM: 106485476
ASN: 102380478(BIRC6)
AMJ: 102562434(BIRC6)
PSS: 102458066(BIRC6)
CMY: 102939825(BIRC6)
CPIC: 101943023(BIRC6)
ACS: 100555646(birc6)
PVT: 110083924(BIRC6)
PBI: 103057238(BIRC6)
PMUR: 107287473(BIRC6)
TSR: 106543083(BIRC6)
PMUA: 114594498(BIRC6)
GJA: 107122648(BIRC6)
XLA: 108716679(birc6.L) 108717825(birc6.S)
XTR: 100135722(birc6)
NPR: 108784163(BIRC6)
DRE: 796547(birc6)
SRX: 107744716(birc6) 107755968
CCAR: 109070478
IPU: 108269600(birc6)
AMEX: 103024424(birc6)
EEE: 113590257(birc6)
TRU: 101070484(birc6)
LCO: 104929305(birc6)
MZE: 101476137(birc6)
ONL: 100690623(birc6)
OLA: 101173043(birc6)
XMA: 102219089(birc6)
XCO: 114138326(birc6)
PRET: 103476564(birc6)
CVG: 107102365(birc6)
NFU: 107375479(birc6)
KMR: 108244051(birc6)
ALIM: 106535036
AOCE: 111586796(birc6)
CSEM: 103387705(birc6)
POV: 109632450(birc6)
LCF: 108884801
SDU: 111236425(birc6)
SLAL: 111672964(birc6)
HCQ: 109523048(birc6)
BPEC: 110158156(birc6)
MALB: 109960050(birc6)
ELS: 105023260(birc6)
SFM: 108918038(birc6)
PKI: 111839558(birc6)
LCM: 102355826(BIRC6)
CMK: 103181770(birc6)
RTP: 109933463(birc6)
SPU: 577866
DME: Dmel_CG6303(Bruce)
DER: 6552038
DSE: 6621674
DSI: Dsimw501_GD20723(Dsim_GD20723)
DAN: 6500248
DSR: 110186836
DPO: Dpse_GA19502(Dpse_Bruce)
DPE: 6588206
DMN: 108154832
DWI: 6651097
DAZ: 108616388
DNV: 108653852
DHE: 111601777
DVI: 6631142
AAG: 5576283
AALB: 109411403
AME: 411115
BIM: 100747538
BTER: 100648203
CCAL: 108626750
OBB: 114880814
NVI: 100117554
CSOL: 105368078
ZNE: 110835557
CEL: CELE_B0403.2(ubc-17)
CBR: CBG10959(Cbr-ubc-17)
CRG: 105338774
MYI: 110461554
LAK: 106181040
NVE: 5518917
AMIL: 114954916
HMG: 100212769
DFA: DFA_01657
 » show all
Reference
  Authors
Qiu XB, Markant SL, Yuan J, Goldberg AL
  Title
Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis.
  Journal
EMBO J 23:800-10 (2004)
DOI:10.1038/sj.emboj.7600075
  Sequence
[hsa:57448]
LinkDB

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