KEGG   ORTHOLOGY: K08765
Entry
K08765                      KO                                     

Name
CPT1A
Definition
carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
Pathway
ko00071  Fatty acid degradation
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04152  AMPK signaling pathway
ko04714  Thermogenesis
ko04920  Adipocytokine signaling pathway
ko04922  Glucagon signaling pathway
ko04931  Insulin resistance
Disease
H00525  Disorders of mitochondrial fatty-acid oxidation
H01981  Carnitine palmitoyltransferase I deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
   04920 Adipocytokine signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
   03320 PPAR signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
  09159 Environmental adaptation
   04714 Thermogenesis
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.21  carnitine O-palmitoyltransferase
     K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
Other DBs
RN: R01923
GO: 0004095
Genes
HSA: 1374(CPT1A)
PTR: 451382(CPT1A)
PPS: 100969017(CPT1A)
GGO: 101128037(CPT1A)
PON: 100446735(CPT1A)
NLE: 100588984(CPT1A)
MCC: 709837(CPT1A)
MCF: 101926183(CPT1A)
CSAB: 103248480(CPT1A)
RRO: 104658386(CPT1A)
RBB: 108538087(CPT1A)
CJC: 100403111(CPT1A)
SBQ: 101044692(CPT1A)
MMU: 12894(Cpt1a)
MCAL: 110285253(Cpt1a)
MPAH: 110338994(Cpt1a)
RNO: 25757(Cpt1a)
MUN: 110546982(Cpt1a)
CGE: 100762166(Cpt1a)
NGI: 103744525(Cpt1a)
HGL: 101716055(Cpt1a)
CCAN: 109700002(Cpt1a)
TUP: 102493851(CPT1A)
CFA: 403583(CPT1A)
VVP: 112924162(CPT1A)
AML: 100482719(CPT1A)
UMR: 103679534(CPT1A)
UAH: 113243994(CPT1A)
ORO: 101373025(CPT1A)
ELK: 111149387
FCA: 101096105(CPT1A)
PTG: 102960681(CPT1A)
PPAD: 109246884(CPT1A)
AJU: 106971087(CPT1A)
BTA: 506812(CPT1A)
BOM: 102265568(CPT1A)
BIU: 109554147(CPT1A)
BBUB: 102399372(CPT1A)
CHX: 102187923(CPT1A)
OAS: 443434(CPT1A)
SSC: 399527(CPT1A)
CFR: 102517968(CPT1A)
CDK: 105104399(CPT1A)
BACU: 103011201(CPT1A)
LVE: 103068754(CPT1A)
OOR: 101271948(CPT1A)
DLE: 111183641(CPT1A)
PCAD: 102992378
ECB: 100009716(CPT1A)
EPZ: 103551279(CPT1A)
EAI: 106844268(CPT1A)
MYB: 102261269(CPT1A)
MYD: 102759504(CPT1A)
MNA: 107537440(CPT1A)
HAI: 109389301(CPT1A)
DRO: 112317040(CPT1A)
PALE: 102886073(CPT1A)
RAY: 107503450(CPT1A)
MJV: 108403489(CPT1A)
LAV: 100665922(CPT1A)
TMU: 101360516
MDO: 100012915(CPT1A)
SHR: 100931262(CPT1A)
PCW: 110195445(CPT1A)
OAA: 100081561(CPT1A)
GGA: 423118(CPT1A)
MGP: 100549362(CPT1A)
CJO: 107314442(CPT1A)
NMEL: 110401227(CPT1A)
APLA: 101799612(CPT1A)
ACYG: 106044877(CPT1A)
TGU: 100226785(CPT1A)
LSR: 110484466(CPT1A)
SCAN: 103826733(CPT1A)
GFR: 102042619(CPT1A)
FAB: 101819946(CPT1A)
PHI: 102103127(CPT1A)
PMAJ: 107205732(CPT1A)
CCAE: 111930121(CPT1A)
CCW: 104693295(CPT1A)
ETL: 114056757(CPT1A)
FPG: 101915684(CPT1A)
FCH: 102056621(CPT1A)
CLV: 102089943(CPT1A)
EGZ: 104132611(CPT1A)
NNI: 104020473(CPT1A)
ACUN: 113481129(CPT1A)
PADL: 103919774(CPT1A)
AAM: 106482194(CPT1A)
ASN: 102370264(CPT1C) 102377631(CPT1A)
AMJ: 102570199(CPT1C) 102572778(CPT1A)
PSS: 102449072(CPT1A)
CMY: 102943921(CPT1A)
CPIC: 101939477(CPT1C) 101941820(CPT1A)
ACS: 100554332(cpt1a) 100560465(cpt1c)
PVT: 110074166(CPT1A) 110079173(CPT1C)
PBI: 103057982(CPT1A) 103062048(CPT1C)
PMUR: 107282437(CPT1C) 107288323
TSR: 106542097 106548161(CPT1A) 106548300(CPT1C)
PMUA: 114581588(CPT1C) 114600127(CPT1A)
GJA: 107111801(CPT1A) 107120350(CPT1C)
XLA: 108713843 108715191 379393(cpt1a.L)
XTR: 100135089(cpt1al) 100490391(cpt1a)
NPR: 108792107 108795865(CPT1A)
DRE: 100333227 449677(cpt1b) 550361(cpt1cb) 558088(cpt1aa) 560000(cpt1ab)
IPU: 108259197(CPT1A) 108264444(cpt1b) 108269775 108275128(cpt1a)
CSEM: 103380127(cpt1b) 103380373(cpt1a) 103382008 103393672
LCM: 102357148(CPT1C) 102359458(CPT1A)
CMK: 103189456(cpt1a)
RTP: 109938367(cpt1c)
SKO: 100373220(CPT1B) 102803200
DME: Dmel_CG12891(whd)
DER: 6547459
DSI: Dsimw501_GD25979(Dsim_GD25979)
DSR: 110189259
DPE: 6592736
DMN: 108158135
DWI: 6637970
DAZ: 108615268
DNV: 108653370
DHE: 111599356
MDE: 101898663
LCQ: 111680063
AAG: 5566521
AALB: 109429376
AME: 550695
BIM: 100749508
BTER: 100647521
CCAL: 108632359
OBB: 114874973
MPHA: 105841151
AEC: 105149369
ACEP: 105619328
PBAR: 105423671
VEM: 105559398
HST: 105188995
DQU: 106750933
CFO: 105248916
LHU: 105679790
PGC: 109856046
OBO: 105280390
PCF: 106785091
NVI: 100121693
CSOL: 105360405
MDL: 103575734
TCA: 657643
DPA: 109533077
ATD: 109605558
NVL: 108568819
BMOR: 101737109
BMAN: 114245113
PMAC: 106720032
PRAP: 110999281
HAW: 110378205
TNL: 113498996
API: 100164300
DNX: 107165513
AGS: 114124632
RMD: 113553702
BTAB: 109040567
CLEC: 106661764
ZNE: 110828915
TUT: 107360655
CEL: CELE_W03F9.4(W03F9.4) CELE_Y46G5A.17(cpt-1)
CBR: CBG06455 CBG07886(Cbr-cpt-1)
TSP: Tsp_10227
OBI: 106870396
EGL: EGR_04498
HMG: 100206022(cpt1a) 100212546(cpt1a)
SPAR: SPRG_02257
TCR: 507211.10
 » show all
Reference
PMID:7892212
  Authors
Britton CH, Schultz RA, Zhang B, Esser V, Foster DW, McGarry JD
  Title
Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.
  Journal
Proc Natl Acad Sci U S A 92:1984-8 (1995)
DOI:10.1073/pnas.92.6.1984
  Sequence
[hsa:1374]
Reference
  Authors
Prip-Buus C, Thuillier L, Abadi N, Prasad C, Dilling L, Klasing J, Demaugre F, Greenberg CR, Haworth JC, Droin V, Kadhom N, Gobin S, Kamoun P, Girard J, Bonnefont JP
  Title
Molecular and enzymatic characterization of a unique carnitine palmitoyltransferase 1A mutation in the Hutterite community.
  Journal
Mol Genet Metab 73:46-54 (2001)
DOI:10.1006/mgme.2001.3176
LinkDB

KEGG   ORTHOLOGY: K19523
Entry
K19523                      KO                                     

Name
CPT1B
Definition
carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
Pathway
ko00071  Fatty acid degradation
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04152  AMPK signaling pathway
ko04714  Thermogenesis
ko04920  Adipocytokine signaling pathway
ko04922  Glucagon signaling pathway
ko04931  Insulin resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
   04920 Adipocytokine signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
   03320 PPAR signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
  09159 Environmental adaptation
   04714 Thermogenesis
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.21  carnitine O-palmitoyltransferase
     K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
Other DBs
RN: R01923
GO: 0004095
Genes
HSA: 1375(CPT1B)
PTR: 470253(CPT1B)
PPS: 100977928(CPT1B)
GGO: 101141306(CPT1B)
PON: 100444942(CPT1B)
NLE: 100591075(CPT1B)
MCC: 720697(CPT1B)
MCF: 101866032(CPT1B)
CSAB: 103223575(CPT1B)
RRO: 104655519(CPT1B)
RBB: 108539398
CJC: 100403864(CPT1B)
SBQ: 101045068(CPT1B)
MMU: 12895(Cpt1b)
MCAL: 110311067(Cpt1b)
MPAH: 110334540(Cpt1b)
RNO: 25756(Cpt1b)
MUN: 110549670(Cpt1b)
CGE: 100770034(Cpt1b)
NGI: 103735491(Cpt1b)
HGL: 101724285(Cpt1b)
CCAN: 109697469(Cpt1b)
OCU: 100353138(CPT1B)
TUP: 102481324(CPT1B)
CFA: 481184(CPT1B)
VVP: 112935810(CPT1B)
AML: 100476203(CPT1B)
UMR: 103673998(CPT1B)
UAH: 113241597(CPT1B)
ORO: 101378588(CPT1B)
ELK: 111157490
FCA: 101083187(CPT1B)
PTG: 102952682(CPT1B)
PPAD: 109265787(CPT1B)
AJU: 106987645(CPT1B)
BTA: 509459(CPT1B)
BOM: 102269192(CPT1B)
BBUB: 102390030(CPT1B)
CHX: 102187210(CPT1B)
OAS: 443193(CPT1B)
SSC: 399528(CPT1B)
CDK: 105106153(CPT1B)
BACU: 103015428(CPT1B)
LVE: 103073664(CPT1B)
OOR: 101269413(CPT1B)
DLE: 111186301(CPT1B)
PCAD: 102980504(CPT1B)
ECB: 100055438(CPT1B)
EPZ: 103564749(CPT1B)
EAI: 106846020(CPT1B)
MYB: 102252400(CPT1B)
MYD: 102764960(CPT1B)
MNA: 107536060(CPT1B)
HAI: 109396636(CPT1B)
DRO: 112321760(CPT1B)
PALE: 102879520(CPT1B)
RAY: 107500269(CPT1B)
MJV: 108407876(CPT1B)
LAV: 100677247(CPT1B)
TMU: 101354017
MDO: 100012188(CPT1B)
SHR: 100930017(CPT1B)
PCW: 110205905(CPT1B)
OAA: 100073995(CPT1B)
NMEL: 110391425
TGU: 115492591(CPT1B)
LSR: 110479260(CPT1B)
PHI: 102105403
ETL: 114071662
FPG: 101916323(CPT1B)
FCH: 102058618(CPT1B)
CLV: 102094115(CPT1B)
NNI: 104009628(CPT1B)
ASN: 102369422(CPT1B)
AMJ: 102571274(CPT1B)
CMY: 102941741(CPT1B)
CPIC: 101948620(CPT1B)
ACS: 100551969(cpt1b)
PVT: 110084411(CPT1B)
PBI: 103049945(CPT1B)
PMUR: 107289217(CPT1B)
PMUA: 114605362(CPT1B)
GJA: 107119323(CPT1B)
XLA: 495682(cpt1b.L)
XTR: 780223(cpt1b)
NPR: 108793465(CPT1B)
LCM: 102352070
CBR: CBG11458
LAK: 106179945
MMI: MMAR_0691
 » show all
Reference
PMID:8679700
  Authors
Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H
  Title
Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.
  Journal
Biochim Biophys Acta 1307:157-61 (1996)
DOI:10.1016/0167-4781(96)00069-3
  Sequence
[hsa:1375]
LinkDB

KEGG   ORTHOLOGY: K19524
Entry
K19524                      KO                                     

Name
CPT1C
Definition
carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
Pathway
ko00071  Fatty acid degradation
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04152  AMPK signaling pathway
ko04714  Thermogenesis
ko04920  Adipocytokine signaling pathway
ko04922  Glucagon signaling pathway
Disease
H00266  Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
   04920 Adipocytokine signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
   03320 PPAR signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
  09159 Environmental adaptation
   04714 Thermogenesis
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.21  carnitine O-palmitoyltransferase
     K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
Other DBs
RN: R01923
GO: 0004095
Genes
HSA: 126129(CPT1C)
PTR: 748258(CPT1C)
PPS: 100978250(CPT1C)
GGO: 101147238(CPT1C)
PON: 100172407(CPT1C)
MCC: 719429(CPT1C)
MCF: 102134440(CPT1C)
CSAB: 103235051(CPT1C)
RRO: 104667209(CPT1C)
RBB: 108535821(CPT1C)
CJC: 100391686(CPT1C)
SBQ: 101043828(CPT1C)
MMU: 78070(Cpt1c)
MCAL: 110297858(Cpt1c)
MPAH: 110319999(Cpt1c)
RNO: 308579(Cpt1c)
CGE: 100767138(Cpt1c)
NGI: 103743677(Cpt1c)
HGL: 101719936(Cpt1c)
CCAN: 109683908(Cpt1c)
OCU: 100341327
TUP: 102486942(CPT1C)
CFA: 100856778(CPT1C)
VVP: 112931178(CPT1C)
AML: 100470509(CPT1C)
UMR: 103657260(CPT1C)
UAH: 113243286(CPT1C)
ORO: 101363059(CPT1C)
ELK: 111160739
FCA: 101095144(CPT1C)
PTG: 102969205(CPT1C)
PPAD: 109253045(CPT1C)
AJU: 106983111(CPT1C)
BTA: 513710(CPT1C)
BOM: 102287746(CPT1C)
BIU: 109572985(CPT1C)
BBUB: 102394789(CPT1C)
CHX: 102173497(CPT1C)
OAS: 101113171(CPT1C)
SSC: 100519258(CPT1C)
CFR: 102505825(CPT1C)
CDK: 105100195(CPT1C)
BACU: 103003703(CPT1C)
LVE: 103073152(CPT1C)
OOR: 101271337(CPT1C)
DLE: 111180605(CPT1C)
PCAD: 102988534(CPT1C)
ECB: 100056027(CPT1C)
EPZ: 103544662(CPT1C)
EAI: 106824163(CPT1C)
MYB: 102242927(CPT1C)
MYD: 102770000(CPT1C)
MNA: 107531792(CPT1C)
HAI: 109391119(CPT1C)
DRO: 112310167(CPT1C)
PALE: 102878033(CPT1C)
RAY: 107498878(CPT1C)
MJV: 108400334(CPT1C)
LAV: 100667001(CPT1C)
TMU: 101347610
MDO: 100030211(CPT1C)
SHR: 105749969(CPT1C)
PCW: 110219957(CPT1C)
OAA: 100681838(CPT1C)
 » show all
Reference
  Authors
Price N, van der Leij F, Jackson V, Corstorphine C, Thomson R, Sorensen A, Zammit V
  Title
A novel brain-expressed protein related to carnitine palmitoyltransferase I.
  Journal
Genomics 80:433-42 (2002)
DOI:10.1006/geno.2002.6845
  Sequence
[hsa:126129]
LinkDB

KEGG   ENZYME: 2.3.1.21
Entry
EC 2.3.1.21                 Enzyme                                 

Name
carnitine O-palmitoyltransferase;
CPT (ambiguous);
CPTo;
outer malonyl-CoA inhibitable carnitine palmitoyltransferase;
CPTi;
CPT I (outer membrane carnitine palmitoyl transferase);
carnitine palmitoyltransferase I;
carnitine palmitoyltransferase II;
CPT-A;
CPT-B;
acylcarnitine transferase;
carnitine palmitoyltransferase;
carnitine palmitoyltransferase-A;
L-carnitine palmitoyltransferase;
palmitoylcarnitine transferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
palmitoyl-CoA:L-carnitine O-palmitoyltransferase
Reaction(IUBMB)
palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine [RN:R01923]
Reaction(KEGG)
R01923
Substrate
palmitoyl-CoA [CPD:C00154];
L-carnitine [CPD:C00318]
Product
CoA [CPD:C00010];
L-palmitoylcarnitine [CPD:C02990]
Comment
Broad specificity to acyl group, over the range C8 to C18; optimal activity with palmitoyl-CoA. cf. EC 2.3.1.7 carnitine O-acetyltransferase and EC 2.3.1.137 carnitine O-octanoyltransferase.
History
EC 2.3.1.21 created 1972
Pathway
ec00071  Fatty acid degradation
Orthology
K08765  carnitine O-palmitoyltransferase 1, liver isoform
K08766  carnitine O-palmitoyltransferase 2
K19523  carnitine O-palmitoyltransferase 1, muscle isoform
K19524  carnitine O-palmitoyltransferase 1, brain isoform
Genes
HSA: 126129(CPT1C) 1374(CPT1A) 1375(CPT1B) 1376(CPT2)
PTR: 451382(CPT1A) 470253(CPT1B) 737945(CPT2) 748258(CPT1C)
PPS: 100969017(CPT1A) 100977928(CPT1B) 100978250(CPT1C) 100983874(CPT2)
GGO: 101128037(CPT1A) 101141306(CPT1B) 101147238(CPT1C) 101147523(CPT2)
PON: 100172407(CPT1C) 100442465(CPT2) 100444942(CPT1B) 100446735(CPT1A)
NLE: 100588984(CPT1A) 100591075(CPT1B) 100594710(CPT2)
MCC: 709837(CPT1A) 714150(CPT2) 719429(CPT1C) 720697(CPT1B)
MCF: 101866032(CPT1B) 101926183(CPT1A) 102134440(CPT1C) 102137160(CPT2)
CSAB: 103223575(CPT1B) 103224794(CPT2) 103235051(CPT1C) 103248480(CPT1A)
RRO: 104655519(CPT1B) 104658386(CPT1A) 104667209(CPT1C) 104669303(CPT2)
RBB: 108531224(CPT2) 108535821(CPT1C) 108538087(CPT1A) 108539398
CJC: 100391686(CPT1C) 100403111(CPT1A) 100403864(CPT1B) 100414414(CPT2)
SBQ: 101033529(CPT2) 101043828(CPT1C) 101044692(CPT1A) 101045068(CPT1B)
MMU: 12894(Cpt1a) 12895(Cpt1b) 12896(Cpt2) 78070(Cpt1c)
MCAL: 110285253(Cpt1a) 110293183(Cpt2) 110297858(Cpt1c) 110311067(Cpt1b)
MPAH: 110319999(Cpt1c) 110323321(Cpt2) 110334540(Cpt1b) 110338994(Cpt1a)
RNO: 25413(Cpt2) 25756(Cpt1b) 25757(Cpt1a) 308579(Cpt1c)
MUN: 110546839 110546852 110546982(Cpt1a) 110549670(Cpt1b) 110563903(Cpt2)
CGE: 100762166(Cpt1a) 100766757(Cpt2) 100767138(Cpt1c) 100770034(Cpt1b)
NGI: 103730274(Cpt2) 103735491(Cpt1b) 103743677(Cpt1c) 103744525(Cpt1a)
HGL: 101709766(Cpt2) 101716055(Cpt1a) 101719936(Cpt1c) 101724285(Cpt1b)
CCAN: 109682869(Cpt2) 109683908(Cpt1c) 109697469(Cpt1b) 109700002(Cpt1a)
TUP: 102481324(CPT1B) 102485726(CPT2) 102486942(CPT1C) 102493851(CPT1A)
CFA: 100856778(CPT1C) 403583(CPT1A) 481184(CPT1B) 489585(CPT2)
VVP: 112924162(CPT1A) 112926120(CPT2) 112931178(CPT1C) 112935810(CPT1B)
AML: 100465139(CPT2) 100470509(CPT1C) 100476203(CPT1B) 100482719(CPT1A)
UMR: 103657260(CPT1C) 103670701(CPT2) 103673998(CPT1B) 103679534(CPT1A)
UAH: 113241597(CPT1B) 113243286(CPT1C) 113243994(CPT1A) 113254653(CPT2)
ORO: 101363059(CPT1C) 101367746(CPT2) 101373025(CPT1A) 101378588(CPT1B)
FCA: 101083187(CPT1B) 101093287(CPT2) 101095144(CPT1C) 101096105(CPT1A)
PTG: 102948684(CPT2) 102952682(CPT1B) 102960681(CPT1A) 102969205(CPT1C)
PPAD: 109246884(CPT1A) 109253045(CPT1C) 109265787(CPT1B) 109266859(CPT2)
AJU: 106971087(CPT1A) 106975005(CPT2) 106983111(CPT1C) 106987645(CPT1B)
BTA: 504502(CPT2) 506812(CPT1A) 509459(CPT1B) 513710(CPT1C)
BOM: 102265568(CPT1A) 102269192(CPT1B) 102281690(CPT2) 102287746(CPT1C)
BIU: 109554147(CPT1A) 109556280(CPT2) 109572985(CPT1C)
BBUB: 102390030(CPT1B) 102394789(CPT1C) 102399372(CPT1A) 102411862(CPT2)
CHX: 102173497(CPT1C) 102180988(CPT2) 102187210(CPT1B) 102187923(CPT1A)
OAS: 101113171(CPT1C) 101118317(CPT2) 443193(CPT1B) 443434(CPT1A)
SSC: 100519258(CPT1C) 100519491(CPT2) 399527(CPT1A) 399528(CPT1B)
CFR: 102505825(CPT1C) 102517968(CPT1A) 102519937(CPT2)
CDK: 105090776(CPT2) 105100195(CPT1C) 105104399(CPT1A) 105106153(CPT1B)
BACU: 103003703(CPT1C) 103007290(CPT2) 103011201(CPT1A) 103015428(CPT1B)
LVE: 103068754(CPT1A) 103073152(CPT1C) 103073664(CPT1B) 103082924(CPT2)
OOR: 101269413(CPT1B) 101271337(CPT1C) 101271948(CPT1A) 101278411(CPT2)
DLE: 111175829(CPT2) 111180605(CPT1C) 111183641(CPT1A) 111186301(CPT1B)
PCAD: 102980504(CPT1B) 102988534(CPT1C) 102989455(CPT2) 102992378
ECB: 100009716(CPT1A) 100055438(CPT1B) 100056027(CPT1C) 100061061(CPT2)
EPZ: 103544662(CPT1C) 103551279(CPT1A) 103558611(CPT2) 103564749(CPT1B)
EAI: 106824163(CPT1C) 106833186(CPT2) 106844268(CPT1A) 106846020(CPT1B)
MYB: 102242927(CPT1C) 102243793(CPT2) 102252400(CPT1B) 102261269(CPT1A)
MYD: 102759504(CPT1A) 102764960(CPT1B) 102766661(CPT2) 102770000(CPT1C)
MNA: 107531792(CPT1C) 107535396(CPT2) 107536060(CPT1B) 107537440(CPT1A)
HAI: 109389301(CPT1A) 109391119(CPT1C) 109395421(CPT2) 109396636(CPT1B)
DRO: 112310167(CPT1C) 112314640(CPT2) 112317040(CPT1A) 112321760(CPT1B)
PALE: 102878033(CPT1C) 102879520(CPT1B) 102886073(CPT1A) 102886099(CPT2)
RAY: 107497952(CPT2) 107498878(CPT1C) 107500269(CPT1B) 107503450(CPT1A)
MJV: 108400334(CPT1C) 108403489(CPT1A) 108407876(CPT1B) 108409318(CPT2)
LAV: 100665512(CPT2) 100665922(CPT1A) 100667001(CPT1C) 100677247(CPT1B)
MDO: 100010920 100012188(CPT1B) 100012915(CPT1A) 100017404(CPT2) 100017446 100030211(CPT1C)
SHR: 100921521(CPT2) 100921785 100927393 100930017(CPT1B) 100931262(CPT1A) 105749969(CPT1C)
PCW: 110195445(CPT1A) 110205905(CPT1B) 110209363 110209364(CPT2) 110219957(CPT1C) 110223414
GGA: 423118(CPT1A) 424649(CPT2)
MGP: 100540756(CPT2) 100549362(CPT1A)
CJO: 107314442(CPT1A) 107317653(CPT2)
NMEL: 110391425 110401227(CPT1A) 110402524(CPT2)
APLA: 101799612(CPT1A) 101804289(CPT2)
ACYG: 106033001(CPT2) 106044877(CPT1A)
TGU: 100222209(CPT2) 100226785(CPT1A) 115492591(CPT1B)
LSR: 110470169(CPT2) 110479260(CPT1B) 110484466(CPT1A)
SCAN: 103815033(CPT2) 103826733(CPT1A)
GFR: 102042619(CPT1A)
FAB: 101819946(CPT1A) 101821336(CPT2)
PHI: 102103127(CPT1A) 102105403 102106295(CPT2)
PMAJ: 107205732(CPT1A) 107208252(CPT2)
CCAE: 111930121(CPT1A) 111944660(CPT2)
CCW: 104693295(CPT1A) 104695521(CPT2)
ETL: 114056757(CPT1A) 114062806(CPT2) 114071662
FPG: 101915684(CPT1A) 101916323(CPT1B) 101916680(CPT2)
FCH: 102046436(CPT2) 102056621(CPT1A) 102058618(CPT1B)
CLV: 102085732(CPT2) 102089943(CPT1A) 102094115(CPT1B)
EGZ: 104131502(CPT2) 104132611(CPT1A)
NNI: 104009358(CPT2) 104009628(CPT1B) 104020473(CPT1A)
ACUN: 113481129(CPT1A) 113483174(CPT2)
PADL: 103913665(CPT2) 103919774(CPT1A)
AAM: 106482194(CPT1A) 106491073(CPT2)
ASN: 102369422(CPT1B) 102370264(CPT1C) 102377631(CPT1A) 102378221(CPT2) 102381122(SPATA9)
AMJ: 102569677(CPT2) 102570199(CPT1C) 102571274(CPT1B) 102572778(CPT1A) 109282261
PSS: 102449072(CPT1A) 102453263(CPT2) 102460096
CMY: 102932067(CPT2) 102941741(CPT1B) 102943921(CPT1A) 102948102
CPIC: 101939045 101939314(CPT2) 101939477(CPT1C) 101941820(CPT1A) 101948620(CPT1B)
ACS: 100551969(cpt1b) 100554332(cpt1a) 100559925(cpt2) 100560465(cpt1c) 100564964
PVT: 110074166(CPT1A) 110078753 110079173(CPT1C) 110082263(CPT2) 110084411(CPT1B)
PBI: 103049945(CPT1B) 103050777(CPT2) 103057982(CPT1A) 103059017 103062048(CPT1C)
PMUR: 107282437(CPT1C) 107283066(CPT2) 107288323 107289217(CPT1B) 107302781
PMUA: 114581588(CPT1C) 114598982(CPT2) 114600127(CPT1A) 114605362(CPT1B) 114606227
GJA: 107111801(CPT1A) 107119323(CPT1B) 107120350(CPT1C) 107120570(CPT2) 107124700
XLA: 108713843 108714327(cpt2.L) 108715191 379393(cpt1a.L) 379893(cpt2.S) 495682(cpt1b.L)
XTR: 100135089(cpt1al) 100490391(cpt1a) 394801(cpt2) 780223(cpt1b)
NPR: 108783819(CPT2) 108792107 108793465(CPT1B) 108795865(CPT1A)
DRE: 100005717(cpt2) 100333227 449677(cpt1b) 550361(cpt1cb) 558088(cpt1aa) 560000(cpt1ab)
IPU: 108259197(CPT1A) 108264444(cpt1b) 108265663(cpt2) 108269775 108275128(cpt1a)
CVG: 107089220(cpt1b) 107091690(cpt2) 107097221 107100949 107104256(cpt1a)
CSEM: 103380127(cpt1b) 103380373(cpt1a) 103382008 103393672 103399070(cpt2)
LCM: 102352070 102353513(CPT2) 102357148(CPT1C) 102359458(CPT1A)
CMK: 103189456(cpt1a) 103191252
RTP: 109913668(cpt2) 109938367(cpt1c)
DME: Dmel_CG12891(whd) Dmel_CG2107(CPT2)
DSE: 6610536
DSI: Dsimw501_GD13716(Dsim_GD13716) Dsimw501_GD25979(Dsim_GD25979)
DAN: 6506889
DVI: 6622348
CSOL: 105360405
CEL: CELE_R07H5.2(cpt-2) CELE_W03F9.4(W03F9.4) CELE_Y46G5A.17(cpt-1)
CBR: CBG06027(Cbr-cpt-2) CBG06455 CBG07886(Cbr-cpt-1) CBG11458
HMG: 100206022(cpt1a) 100212546(cpt1a) 100214547(cpt2)
MMI: MMAR_0691
 » show all
Reference
1
  Authors
Derrick, J.P., Tubbs, P.K. and Ramsay, R.R.
  Title
Purification and properties of an easily solubilized L-carnitine palmitoyltransferase from beef-liver mitochondria.
  Journal
Biochem Soc Trans 14:698 (1986)
Reference
2  [PMID:3342008]
  Authors
Healy MJ, Kerner J, Bieber LL.
  Title
Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?
  Journal
Biochem J 249:231-7 (1988)
DOI:10.1042/bj2490231
Reference
3  [PMID:6630173]
  Authors
Miyazawa S, Ozasa H, Osumi T, Hashimoto T.
  Title
Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.
  Journal
J Biochem (Tokyo) 94:529-42 (1983)
DOI:10.1093/oxfordjournals.jbchem.a134384
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.21
IUBMB Enzyme Nomenclature: 2.3.1.21
ExPASy - ENZYME nomenclature database: 2.3.1.21
BRENDA, the Enzyme Database: 2.3.1.21
CAS: 9068-41-1
LinkDB

KEGG   REACTION: R01923
Entry
R01923                      Reaction                               

Name
palmitoyl-CoA:L-carnitine O-palmitoyltransferase
Definition
Palmitoyl-CoA + L-Carnitine <=> CoA + L-Palmitoylcarnitine
Equation
Reaction class
RC00004  C00010_C00154
RC00037  C00318_C02990
RC02816  C00154_C02990
Enzyme
Pathway
rn00071  Fatty acid degradation
rn01212  Fatty acid metabolism
Orthology
K08765  carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K08766  carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K19523  carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524  carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
Other DBs
RHEA: 12664
LinkDB

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