KEGG   ORTHOLOGY: K08765Help
Entry
K08765                      KO                                     

Name
CPT1A
Definition
carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
Pathway
ko00071  Fatty acid degradation
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04152  AMPK signaling pathway
ko04714  Thermogenesis
ko04920  Adipocytokine signaling pathway
ko04922  Glucagon signaling pathway
ko04931  Insulin resistance
Disease
H00525  Disorders of mitochondrial fatty-acid oxidation
H01981  Carnitine palmitoyltransferase I deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
   04920 Adipocytokine signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
   03320 PPAR signaling pathway
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
  09159 Environmental adaptation
   04714 Thermogenesis
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.21  carnitine O-palmitoyltransferase
     K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
BRITE hierarchy
Other DBs
RN: R01923
GO: 0004095
Genes
HSA: 1374(CPT1A)
PTR: 451382(CPT1A)
PPS: 100969017(CPT1A)
GGO: 101128037(CPT1A) 109028728 109028908
PON: 100446735(CPT1A)
NLE: 100588984(CPT1A)
MCC: 709837(CPT1A)
MCF: 101926183(CPT1A)
CSAB: 103248480(CPT1A)
RRO: 104658386(CPT1A)
RBB: 108538087(CPT1A)
CJC: 100403111(CPT1A)
SBQ: 101044692(CPT1A)
MMU: 12894(Cpt1a)
MCAL: 110285253(Cpt1a)
MPAH: 110338994(Cpt1a)
RNO: 25757(Cpt1a)
MUN: 110546982(Cpt1a)
CGE: 100762166(Cpt1a)
NGI: 103744525(Cpt1a)
HGL: 101716055(Cpt1a)
CCAN: 109700002(Cpt1a)
TUP: 102493851(CPT1A)
CFA: 403583(CPT1A)
VVP: 112924162(CPT1A)
AML: 100482719(CPT1A)
UMR: 103679534(CPT1A)
UAH: 113243994(CPT1A)
ORO: 101373025(CPT1A)
FCA: 101096105(CPT1A)
PTG: 102960681(CPT1A)
AJU: 106971087(CPT1A)
BTA: 506812(CPT1A)
BOM: 102265568(CPT1A)
BIU: 109554147(CPT1A)
BBUB: 102399372(CPT1A)
PHD: 102328573(CPT1A)
CHX: 102187923(CPT1A)
OAS: 443434(CPT1A)
SSC: 399527(CPT1A)
CFR: 102517968(CPT1A)
CDK: 105104399(CPT1A)
BACU: 103011201(CPT1A)
LVE: 103068754(CPT1A)
OOR: 101271948(CPT1A)
DLE: 111183641(CPT1A)
PCAD: 102992378 114488029(CPT1A)
ECB: 100009716(CPT1A)
EPZ: 103551279(CPT1A)
EAI: 106844268(CPT1A)
MYB: 102261269(CPT1A)
MYD: 102759504(CPT1A)
MNA: 107537440(CPT1A)
HAI: 109389301(CPT1A)
RSS: 109460361(CPT1A)
DRO: 112317040(CPT1A)
PALE: 102886073(CPT1A)
RAY: 107503450(CPT1A)
LAV: 100665922(CPT1A)
TMU: 101360516
MDO: 100012915(CPT1A)
SHR: 100931262(CPT1A)
PCW: 110195445(CPT1A)
OAA: 100081561(CPT1A)
GGA: 423118(CPT1A)
MGP: 100549362(CPT1A)
CJO: 107314442(CPT1A)
NMEL: 110401227(CPT1A)
APLA: 101799612(CPT1A)
ACYG: 106044877(CPT1A)
TGU: 100226785(CPT1A)
LSR: 110484466(CPT1A)
SCAN: 103826733(CPT1A)
GFR: 102042619(CPT1A)
FAB: 101819946(CPT1A)
PHI: 102103127(CPT1A)
PMAJ: 107205732(CPT1A)
CCAE: 111930121(CPT1A)
CCW: 104693295(CPT1A)
ETL: 114056757(CPT1A)
FPG: 101915684(CPT1A)
FCH: 102056621(CPT1A)
CLV: 102089943(CPT1A)
EGZ: 104132611(CPT1A)
NNI: 104020473(CPT1A)
ACUN: 113481129(CPT1A)
PADL: 103919774(CPT1A)
AAM: 106482194(CPT1A)
ASN: 102370264(CPT1C) 102377631(CPT1A)
AMJ: 102570199(CPT1C) 102572778(CPT1A)
PSS: 102449072(CPT1A)
CMY: 102943921(CPT1A)
CPIC: 101939477(CPT1C) 101941820(CPT1A)
ACS: 100554332(cpt1a) 100560465(cpt1c)
PVT: 110074166(CPT1A) 110079173(CPT1C)
PBI: 103057982(CPT1A) 103062048(CPT1C)
PMUR: 107282437(CPT1C) 107288323
GJA: 107111801(CPT1A) 107120350(CPT1C)
XLA: 108713843 108715191 379393(cpt1a.L)
XTR: 100135089(cpt1a) 100490391
NPR: 108792107 108795865(CPT1A)
DRE: 100333227 558088(cpt1aa) 560000(cpt1ab)
IPU: 108259197(CPT1A) 108264444(cpt1b) 108269775 108275128(cpt1a)
LCM: 102352070 102357148(CPT1C) 102359458(CPT1A)
CMK: 103174384 103189456(cpt1a)
SKO: 100373220(CPT1B) 102803200
DME: Dmel_CG12891(whd)
DER: 6547459
DPE: 6592736
DSI: Dsimw501_GD25979(Dsim_GD25979)
DWI: 6637970
DAZ: 108615268
DNV: 108653370
DHE: 111599356
MDE: 101898663
LCQ: 111680063
AAG: 5566521
AME: 550695
BIM: 100749508
BTER: 100647521
MPHA: 105841151
AEC: 105149369
ACEP: 105619328
PBAR: 105423671
VEM: 105559398
HST: 105188995
DQU: 106750933
CFO: 105248916
LHU: 105679790
PGC: 109856046
OBO: 105280390
PCF: 106785091
NVI: 100121693
MDL: 103575734
TCA: 657643
DPA: 109533077
NVL: 108568819
BMOR: 101737109
PMAC: 106720032
PRAP: 110999281
HAW: 110378205
TNL: 113498996
PXY: 105381350
API: 100164300
DNX: 107165513
AGS: 114124632
BTAB: 109040567
CLEC: 106661764
ZNE: 110828915
TUT: 107360655
CEL: CELE_Y46G5A.17(cpt-1)
CBR: CBG07886(Cbr-cpt-1)
BMY: Bm1_02015
TSP: Tsp_10227
EGL: EGR_04498
HMG: 100206022(cpt1a) 100212546(cpt1a)
SPAR: SPRG_02257
TCR: 507211.10
MMI: MMAR_0691
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7892212
  Authors
Britton CH, Schultz RA, Zhang B, Esser V, Foster DW, McGarry JD
  Title
Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.
  Journal
Proc Natl Acad Sci U S A 92:1984-8 (1995)
DOI:10.1073/pnas.92.6.1984
  Sequence
[hsa:1374]
Reference
  Authors
Prip-Buus C, Thuillier L, Abadi N, Prasad C, Dilling L, Klasing J, Demaugre F, Greenberg CR, Haworth JC, Droin V, Kadhom N, Gobin S, Kamoun P, Girard J, Bonnefont JP
  Title
Molecular and enzymatic characterization of a unique carnitine palmitoyltransferase 1A mutation in the Hutterite community.
  Journal
Mol Genet Metab 73:46-54 (2001)
DOI:10.1006/mgme.2001.3176
LinkDB All DBs

KEGG   ORTHOLOGY: K19523Help
Entry
K19523                      KO                                     

Name
CPT1B
Definition
carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
Pathway
ko00071  Fatty acid degradation
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04152  AMPK signaling pathway
ko04714  Thermogenesis
ko04920  Adipocytokine signaling pathway
ko04922  Glucagon signaling pathway
ko04931  Insulin resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
   04920 Adipocytokine signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
   03320 PPAR signaling pathway
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
  09159 Environmental adaptation
   04714 Thermogenesis
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.21  carnitine O-palmitoyltransferase
     K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform
BRITE hierarchy
Other DBs
RN: R01923
GO: 0004095
Genes
HSA: 1375(CPT1B)
PTR: 470253(CPT1B)
PPS: 100977928(CPT1B)
GGO: 101141306(CPT1B)
PON: 100444942(CPT1B)
NLE: 100591075(CPT1B)
MCC: 720697(CPT1B)
MCF: 101866032(CPT1B)
CSAB: 103223575(CPT1B)
RRO: 104655519(CPT1B)
CJC: 100403864(CPT1B)
SBQ: 101045068(CPT1B)
MMU: 12895(Cpt1b)
MCAL: 110311067(Cpt1b)
MPAH: 110334540(Cpt1b)
RNO: 25756(Cpt1b)
MUN: 110549670(Cpt1b)
CGE: 100770034(Cpt1b)
NGI: 103735491(Cpt1b)
HGL: 101724285(Cpt1b)
CCAN: 109697469(Cpt1b)
OCU: 100353138(CPT1B)
TUP: 102481324(CPT1B)
CFA: 481184(CPT1B)
VVP: 112935810(CPT1B)
AML: 100476203(CPT1B)
UMR: 103673998(CPT1B)
UAH: 113241597(CPT1B)
ORO: 101378588(CPT1B)
FCA: 101083187(CPT1B)
PTG: 102952682(CPT1B)
AJU: 106987645(CPT1B)
BTA: 509459(CPT1B)
BOM: 102269192(CPT1B)
BBUB: 102390030(CPT1B)
PHD: 102343440(CPT1B)
CHX: 102187210(CPT1B)
OAS: 443193(CPT1B)
SSC: 399528(CPT1B)
CFR: 102524549(CPT1B)
CDK: 105106153(CPT1B)
BACU: 103015428(CPT1B)
LVE: 103073664(CPT1B)
OOR: 101269413(CPT1B)
DLE: 111186301(CPT1B)
PCAD: 102980504(CPT1B)
ECB: 100055438(CPT1B)
EPZ: 103564749(CPT1B)
EAI: 106846020(CPT1B)
MYB: 102252400(CPT1B)
MYD: 102764960(CPT1B)
MNA: 107536060(CPT1B)
HAI: 109396636(CPT1B)
RSS: 109438164(CPT1B)
DRO: 112321760(CPT1B)
PALE: 102879520(CPT1B)
RAY: 107500269(CPT1B)
LAV: 100677247(CPT1B)
TMU: 101354017
MDO: 100012188(CPT1B)
SHR: 100930017(CPT1B)
PCW: 110205905(CPT1B)
OAA: 100073995(CPT1B)
NMEL: 110391425
ACYG: 106048146(CPT1B)
LSR: 110479260(CPT1B)
PHI: 102105403
PMAJ: 107199664
ETL: 114071662
FPG: 101916323(CPT1B)
FCH: 102058618(CPT1B)
CLV: 102094115(CPT1B)
NNI: 104009628(CPT1B)
ASN: 102369422(CPT1B)
AMJ: 102571274(CPT1B) 106738940
CMY: 102941741(CPT1B)
CPIC: 101948620(CPT1B)
ACS: 100551969(cpt1b)
PVT: 110084411(CPT1B)
PBI: 103049945(CPT1B)
PMUR: 107289217(CPT1B)
GJA: 107119323(CPT1B)
XLA: 495682(cpt1b.L)
XTR: 780223(cpt1b)
NPR: 108793465(CPT1B)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8679700
  Authors
Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H
  Title
Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.
  Journal
Biochim Biophys Acta 1307:157-61 (1996)
DOI:10.1016/0167-4781(96)00069-3
  Sequence
[hsa:1375]
LinkDB All DBs

KEGG   ORTHOLOGY: K19524Help
Entry
K19524                      KO                                     

Name
CPT1C
Definition
carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
Pathway
ko00071  Fatty acid degradation
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
ko04152  AMPK signaling pathway
ko04714  Thermogenesis
ko04920  Adipocytokine signaling pathway
ko04922  Glucagon signaling pathway
Disease
H00266  Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
   04920 Adipocytokine signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
   03320 PPAR signaling pathway
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
  09159 Environmental adaptation
   04714 Thermogenesis
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.21  carnitine O-palmitoyltransferase
     K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform
BRITE hierarchy
Other DBs
RN: R01923
GO: 0004095
Genes
HSA: 126129(CPT1C)
PTR: 748258(CPT1C)
PPS: 100978250(CPT1C)
GGO: 101147238(CPT1C)
PON: 100172407(CPT1C)
NLE: 100586407(CPT1C)
MCC: 719429(CPT1C)
MCF: 102134440(CPT1C)
CSAB: 103235051(CPT1C)
RRO: 104667209(CPT1C)
RBB: 108535821(CPT1C)
CJC: 100391686(CPT1C)
SBQ: 101043828(CPT1C)
MMU: 78070(Cpt1c)
MCAL: 110297858(Cpt1c)
MPAH: 110319999(Cpt1c)
RNO: 308579(Cpt1c)
CGE: 100767138(Cpt1c)
NGI: 103743677(Cpt1c)
HGL: 101719936(Cpt1c)
CCAN: 109683908(Cpt1c)
TUP: 102486942(CPT1C)
CFA: 100856778(CPT1C)
VVP: 112931178(CPT1C)
AML: 100470509(CPT1C)
UMR: 103657260(CPT1C)
UAH: 113243286(CPT1C)
ORO: 101363059(CPT1C)
FCA: 101095144(CPT1C)
PTG: 102969205(CPT1C)
AJU: 106983111(CPT1C)
BTA: 513710(CPT1C)
BOM: 102287746(CPT1C)
BIU: 109572985(CPT1C)
BBUB: 102394789(CPT1C)
PHD: 102336252(CPT1C)
CHX: 102173497(CPT1C)
OAS: 101113171(CPT1C)
SSC: 100519258(CPT1C)
CFR: 102505825(CPT1C)
CDK: 105100195(CPT1C)
BACU: 103003703(CPT1C)
LVE: 103073152(CPT1C)
OOR: 101271337(CPT1C)
DLE: 111180605(CPT1C)
PCAD: 102988534(CPT1C)
ECB: 100056027(CPT1C)
EPZ: 103544662(CPT1C)
EAI: 106824163(CPT1C)
MYB: 102242927(CPT1C)
MYD: 102770000(CPT1C)
MNA: 107531792(CPT1C)
HAI: 109391119(CPT1C)
RSS: 109452576(CPT1C)
DRO: 112310167(CPT1C)
PALE: 102878033(CPT1C)
RAY: 107498878(CPT1C)
LAV: 100667001(CPT1C)
TMU: 101347610
SHR: 105749969(CPT1C)
PCW: 110219957(CPT1C)
OAA: 100681838(CPT1C)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Price N, van der Leij F, Jackson V, Corstorphine C, Thomson R, Sorensen A, Zammit V
  Title
A novel brain-expressed protein related to carnitine palmitoyltransferase I.
  Journal
Genomics 80:433-42 (2002)
DOI:10.1006/geno.2002.6845
  Sequence
[hsa:126129]
LinkDB All DBs

KEGG   REACTION: R01923Help
Entry
R01923                      Reaction                               

Name
palmitoyl-CoA:L-carnitine O-palmitoyltransferase
Definition
Palmitoyl-CoA + L-Carnitine <=> CoA + L-Palmitoylcarnitine
Equation
Reaction class
RC00004  C00010_C00154
RC00037  C00318_C02990
RC02816  C00154_C02990
Enzyme
Pathway
rn00071  Fatty acid degradation
rn01212  Fatty acid metabolism
Orthology
K08765  carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K08766  carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K19523  carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524  carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
Other DBs
RHEA: 12664
LinkDB All DBs

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