K08784                      KO                                     

HtrA serine peptidase 1 [EC:3.4.21.-]
H00821  Age-related macular degeneration
H01757  Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08784  HTRA1, PRSS11; HtrA serine peptidase 1
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K08784  HTRA1, PRSS11; HtrA serine peptidase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
     K08784  HTRA1, PRSS11; HtrA serine peptidase 1
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K08784  HTRA1, PRSS11; HtrA serine peptidase 1
Chaperones and folding catalysts [BR:ko03110]
 Other chaperones and cochaperones
  DegP / HtrA
   K08784  HTRA1, PRSS11; HtrA serine peptidase 1
HSA: 5654(HTRA1)
PTR: 450792(HTRA1)
PPS: 100984844(HTRA1)
GGO: 101127178(HTRA1)
PON: 100437050(HTRA1)
NLE: 100583976(HTRA1)
MCC: 705855(HTRA1)
MCF: 102126844(HTRA1)
CSAB: 103216638(HTRA1)
RRO: 104658066(HTRA1)
RBB: 108529745(HTRA1)
CJC: 100398769(HTRA1)
SBQ: 101030381(HTRA1)
MMU: 56213(Htra1)
MCAL: 110298288(Htra1)
MPAH: 110322568(Htra1)
RNO: 65164(Htra1)
MUN: 110558355(Htra1)
CGE: 100762962(Htra1)
NGI: 103729266(Htra1)
HGL: 101703079(Htra1)
CCAN: 109691638(Htra1)
OCU: 100008705(HTRA1)
TUP: 102497616(HTRA1)
CFA: 477852(HTRA1)
VVP: 112916926(HTRA1)
AML: 100468862(HTRA1)
UMR: 103659391(HTRA1)
UAH: 113252019(HTRA1)
ORO: 101377025(HTRA1)
ELK: 111144826
FCA: 101095920(HTRA1)
PTG: 102949412(HTRA1)
PPAD: 109273008(HTRA1)
AJU: 106969384(HTRA1)
BTA: 282326(HTRA1)
BOM: 102269881(HTRA1)
BIU: 109553084(HTRA1)
BBUB: 102396828(HTRA1)
CHX: 102174540(HTRA1)
OAS: 101101854(HTRA1)
SSC: 100515628(HTRA1)
CFR: 102510440(HTRA1)
CDK: 105104228(HTRA1)
BACU: 103007240(HTRA1)
LVE: 103087438(HTRA1)
OOR: 101269446(HTRA1)
DLE: 111172233(HTRA1)
PCAD: 114485368
ECB: 100064570(HTRA1)
EPZ: 103542384(HTRA1)
EAI: 106824430(HTRA1)
MYD: 102764423(HTRA1)
MNA: 107532666(HTRA1)
HAI: 109382985(HTRA1)
DRO: 112300265(HTRA1)
PALE: 102883658(HTRA1)
RAY: 107512984(HTRA1)
MJV: 108396897(HTRA1)
LAV: 100675235(HTRA1)
TMU: 101352358
MDO: 100025560(HTRA1)
SHR: 100930647(HTRA1)
PCW: 110202867(HTRA1)
OAA: 100093346(HTRA1)
GGA: 100857572(HTRA1)
MGP: 100541363(HTRA1)
CJO: 107316299(HTRA1)
NMEL: 110400047(HTRA1)
APLA: 101793219(HTRA1)
ACYG: 106038992(HTRA1)
TGU: 100219623(HTRA1)
LSR: 110468435(HTRA1)
SCAN: 103814108(HTRA1)
GFR: 102043139(HTRA1)
FAB: 101813424(HTRA1)
PHI: 102106039(HTRA1)
PMAJ: 107206893(HTRA1)
CCAE: 111931380(HTRA1)
CCW: 104694592(HTRA1)
ETL: 114069420(HTRA1)
FCH: 102058838(HTRA1)
CLV: 102096252(HTRA1)
EGZ: 104123677(HTRA1)
NNI: 104020575(HTRA1)
ACUN: 113481713(HTRA1)
PADL: 103918648(HTRA1)
AAM: 106499018(HTRA1)
ASN: 102385435(HTRA1)
AMJ: 102568843(HTRA1)
PSS: 102448440(HTRA1)
CMY: 102941421(HTRA1)
CPIC: 101942959(HTRA1)
ACS: 100559415(htra4) 100564246(htra1)
PVT: 110072161(HTRA4) 110075336(HTRA1)
PBI: 103055911 103064390(HTRA1)
PMUR: 107288605(HTRA1)
TSR: 106538760
PMUA: 114597418(HTRA1)
GJA: 107122324(HTRA1)
XLA: 108696094(htra1.L) 108711647(htra4.L) 108712278 496061(htra1.S)
XTR: 100488607(htra4) 780187(htra1)
DRE: 100334257(htra4) 431766(htra1a) 565082(htra1b)
CCAR: 109080112
IPU: 108255963(htra4) 108270147 108273788(htra1)
NCC: 104944757 104946544(htra1)
OLA: 101160199(htra1) 105355810
XMA: 102218195 102219577(htra1)
XCO: 114137439 114151684(htra1)
PRET: 103476703 103481869(htra1)
CVG: 107091711 107094975(htra1)
NFU: 107375930 107387249(htra1)
ALIM: 106528240(htra1) 106537336
CSEM: 103382293 103387077(htra1)
ELS: 105006447(htra1) 105010563 105014508(htra4)
SFM: 108932767 108939508(htra1) 108940300(htra4)
LCM: 102345424(HTRA1) 102361645(HTRA4)
CMK: 103171855 103185432(htra1)
RTP: 109930711 109931827(htra1)
CIN: 100182899
 » show all
Oka C, Tsujimoto R, Kajikawa M, Koshiba-Takeuchi K, Ina J, Yano M, Tsuchiya A, Ueta Y, Soma A, Kanda H, Matsumoto M, Kawaichi M
HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins.
Development 131:1041-53 (2004)
Campioni M, Severino A, Manente L, Tuduce IL, Toldo S, Caraglia M, Crispi S, Ehrmann M, He X, Maguire J, De Falco M, De Luca A, Shridhar V, Baldi A
The serine protease HtrA1 specifically interacts and degrades the tuberous sclerosis complex 2 protein.
Mol Cancer Res 8:1248-60 (2010)

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