KEGG   ORTHOLOGY: K08794
Entry
K08794                      KO                                     

Name
CAMK1
Definition
calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
Pathway
map04020  Calcium signaling pathway
map04921  Oxytocin signaling pathway
map04925  Aldosterone synthesis and secretion
map05214  Glioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
   04925 Aldosterone synthesis and secretion
    K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
 09160 Human Diseases
  09162 Cancer: specific types
   05214 Glioma
    K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  CAMK1 family [OT]
   K08794  CAMK1; calcium/calmodulin-dependent protein kinase I
Other DBs
GO: 0004683
Genes
HSA: 57118(CAMK1D) 57172(CAMK1G) 8536(CAMK1)
PTR: 450308(CAMK1D) 460153(CAMK1) 469667(CAMK1G)
PPS: 100979439(CAMK1D) 100980159(CAMK1G) 100995267(CAMK1)
GGO: 101127167(CAMK1D) 101140710(CAMK1) 101146568(CAMK1G)
PON: 100432476(CAMK1) 100460905(CAMK1D) 100462399(CAMK1G)
NLE: 100581209(CAMK1D) 100592807(CAMK1G) 100605884(CAMK1)
MCC: 697661(CAMK1D) 700212(CAMK1) 717624(CAMK1G)
MCF: 101865245(CAMK1G) 102119555(CAMK1) 102120054(CAMK1D)
CSAB: 103227977(CAMK1) 103230156(CAMK1G) 103237895(CAMK1D)
CATY: 105573807(CAMK1D) 105577074(CAMK1G) 105585762(CAMK1)
PANU: 101003109(CAMK1) 101005661(CAMK1G) 101024349(CAMK1D)
RRO: 104664168(CAMK1G) 104664882(CAMK1D)
RBB: 108538536(CAMK1D) 108539550(CAMK1G)
TFN: 117075386(CAMK1G) 117082480(CAMK1D) 117083218(CAMK1)
PTEH: 111531099(CAMK1G) 111546951(CAMK1) 111550010(CAMK1D)
CJC: 100393309(CAMK1D) 100399376(CAMK1) 100400126(CAMK1G)
SBQ: 101041865(CAMK1G) 101042068(CAMK1D) 101042674(CAMK1)
MMUR: 105869034(CAMK1) 105871992(CAMK1D) 105880567(CAMK1G)
MMU: 215303(Camk1g) 52163(Camk1)
MCAL: 110296113(Camk1) 110299437(Camk1g)
MPAH: 110313699(Camk1) 110321576(Camk1g)
RNO: 171358(Camk1g) 171503(Camk1)
MCOC: 116069176(Camk1g) 116081906(Camk1d) 116099389(Camk1)
MUN: 110548926(Camk1) 110559814(Camk1g)
CGE: 100755149(Camk1) 100763374(Camk1g)
PLEU: 114689600(Camk1) 114702392(Camk1g) 114708480(Camk1d)
NGI: 103727073(Camk1g) 103746367(Camk1d) 103751418(Camk1)
HGL: 101697150(Camk1) 101717828(Camk1d) 101718073(Camk1g)
CCAN: 109682439(Camk1d) 109686994(Camk1) 109697855(Camk1g)
OCU: 100343158(CAMK1G) 100343415(CAMK1D)
TUP: 102473558(CAMK1) 102478578(CAMK1D) 102500231(CAMK1G)
CFA: 484665(CAMK1) 490273(CAMK1G) 607636(CAMK1D)
VVP: 112907140(CAMK1G) 112933349(CAMK1D) 112933670(CAMK1)
VLG: 121495701(CAMK1G) 121497556(CAMK1D)
AML: 100471632(CAMK1) 100477852(CAMK1D)
UMR: 103672536(CAMK1G) 103676294(CAMK1D)
UAH: 113241069(CAMK1D) 113262641(CAMK1G)
ORO: 101363153(CAMK1D) 101368451(CAMK1G) 101375985(CAMK1)
MPUF: 101678852(CAMK1D) 101689208(CAMK1G) 101693787(CAMK1)
EJU: 114203638 114207710(CAMK1) 114217709(CAMK1D) 114225953(CAMK1G)
MLX: 118014278(CAMK1G) 118021581(CAMK1D)
FCA: 101084178(CAMK1) 101089070(CAMK1G) 101097250(CAMK1D)
PTG: 102961856(CAMK1D) 102966233(CAMK1G)
PPAD: 109254386(CAMK1) 109255143(CAMK1G) 109273723(CAMK1D)
AJU: 106971001(CAMK1D) 106981810(CAMK1G)
HHV: 120226588(CAMK1D) 120230511(CAMK1G) 120231295(CAMK1)
BTA: 511504(CAMK1G) 520498(CAMK1) 526873(CAMK1D)
BOM: 102268851(CAMK1) 102283599(CAMK1D)
BIU: 109567581(CAMK1D) 109570799(CAMK1G) 109576206(CAMK1)
BBUB: 102393547(CAMK1) 102415997(CAMK1D)
CHX: 102174671(CAMK1D) 102185318(CAMK1)
OAS: 101103762(CAMK1) 101108939(CAMK1D)
ODA: 120867742(CAMK1) 120869259(CAMK1D) 120880019(CAMK1G)
SSC: 100511150(CAMK1D) 100512553(CAMK1G)
CFR: 102503486(CAMK1G) 102506579(CAMK1D) 102519744(CAMK1)
CDK: 105099333(CAMK1G) 105100308(CAMK1D)
BACU: 103002479(CAMK1G) 103013193(CAMK1D)
LVE: 103087450(CAMK1G) 103090123(CAMK1D)
OOR: 101272454(CAMK1D) 101285365(CAMK1G)
DLE: 111178006(CAMK1D) 111184726(CAMK1G)
PCAD: 102975098(CAMK1) 102985851(CAMK1D) 102993502 114486038(CAMK1G)
ECB: 100052300(CAMK1) 100056611(CAMK1G) 100056740(CAMK1D)
EPZ: 103548654(CAMK1G) 103558519(CAMK1D) 103566626(CAMK1)
EAI: 106827198(CAMK1G) 106835609(CAMK1) 106836930(CAMK1D)
MYB: 102242762(CAMK1) 102244367(CAMK1D) 102257861(CAMK1G)
MYD: 102756176(CAMK1D) 102760326(CAMK1)
MMYO: 118668036(CAMK1) 118672718(CAMK1G) 118677415(CAMK1D)
MNA: 107530231(CAMK1D) 107532942(CAMK1G) 107534757(CAMK1)
HAI: 109390487(CAMK1D) 109396120(CAMK1G)
DRO: 112296400(CAMK1G) 112301212(CAMK1) 112322693(CAMK1D)
SHON: 118974246(CAMK1G) 118993351(CAMK1) 119000844(CAMK1D)
AJM: 119041384(CAMK1) 119043086(CAMK1G) 119056691(CAMK1D)
MMF: 118616835(CAMK1D) 118633142(CAMK1) 118637345(CAMK1G)
PALE: 102893878(CAMK1D) 102896085(CAMK1G)
RAY: 107504874(CAMK1) 107517631(CAMK1G)
MJV: 108384500(CAMK1G) 108394998 108407975(CAMK1)
TOD: 119233725(CAMK1G) 119244688(CAMK1D)
LAV: 100653646(CAMK1D) 100661819(CAMK1)
MDO: 100011530(CAMK1D) 100024012(CAMK1)
SHR: 100922469(CAMK1G) 100927184(CAMK1D)
PCW: 110217357(CAMK1D) 110222697(CAMK1G)
OAA: 100078245(CAMK1G) 100085379(CAMK1D)
GGA: 419859(CAMK1G) 425522(CAMK1D)
PCOC: 116236996(CAMK1G) 116244379(CAMK1D)
MGP: 100540470(CAMK1D) 100550058(CAMK1G)
CJO: 107317642(CAMK1D) 107324780(CAMK1G)
NMEL: 110388298(CAMK1G) 110392267(CAMK1D)
APLA: 101802855(CAMK1G)
ACYG: 106041372(CAMK1G) 106046193(CAMK1D)
TGU: 100221874(CAMK1D) 105758886(CAMK1G)
LSR: 110470930(CAMK1D) 110475396(CAMK1G)
SCAN: 103813567(CAMK1D) 103823276(CAMK1G)
PMOA: 120495941(CAMK1G) 120512515(CAMK1D)
GFR: 102042825(CAMK1G) 102045361(CAMK1D)
FAB: 101812613(CAMK1D) 101813070(CAMK1G)
PHI: 102100547(CAMK1D) 102114311(CAMK1G)
PMAJ: 107204376(CAMK1D) 107214836(CAMK1G)
CCAE: 111923213(CAMK1D) 111939803(CAMK1G)
CCW: 104692329(CAMK1G) 104694527(CAMK1D)
ETL: 114063147(CAMK1G) 114066626(CAMK1D)
FPG: 101910675(CAMK1G) 101914885(CAMK1D)
FCH: 102045860(CAMK1D) 102051618(CAMK1G)
CLV: 102085162(CAMK1D) 102088569(CAMK1G)
EGZ: 104126800(CAMK1G) 104135764(CAMK1D)
NNI: 104010307(CAMK1G) 104014633(CAMK1D)
ACUN: 113488684(CAMK1D)
PADL: 103915027(CAMK1D) 103923569(CAMK1G)
AAM: 106485116(CAMK1D) 106490977(CAMK1G)
ASN: 102376356(CAMK1D) 102386449(CAMK1G)
AMJ: 102562581(CAMK1D) 102569031(CAMK1G)
CPOO: 109315803(CAMK1D) 109317900(CAMK1G)
GGN: 109295282(CAMK1G)
PSS: 102457942(CAMK1G) 102462336(CAMK1D)
CMY: 102946231(CAMK1G)
CPIC: 101933634(CAMK1G) 101938057(CAMK1D)
TST: 117874640(CAMK1D) 117877443(CAMK1G)
CABI: 116832981(CAMK1G) 116835455(CAMK1D)
ACS: 100551763(camk1d) 100558473(camk1g)
PVT: 110072369(CAMK1G) 110081228(CAMK1D)
TSR: 106539751(CAMK1G) 106553363(CAMK1D)
PGUT: 117663839(CAMK1G)
PMUA: 114599350(CAMK1G) 114605753(CAMK1D)
ZVI: 118088703(CAMK1G) 118091060(CAMK1D)
GJA: 107108298(CAMK1G) 107109980 107111080(CAMK1D)
XLA: 108708050(camk1g.L) 108709380 379971(camk1.S) 399357(camk1d.S) 444524
XTR: 100493115(camk1d) 100494644(camk1g)
NPR: 108784810(CAMK1D) 108804406(CAMK1)
DRE: 100144566(camk1da) 335654(camk1ga) 393802(camk1gb) 555945(camk1a) 791176(camk1db) 794026(camk1b)
IPU: 108254900(Camk1) 108271991 108275359 108276228(camk1g) 108279878(Camk1d)
ELY: 117249303(camk1da) 117257165(camk1b) 117257426 117257437(camk1a) 117257823(camk1gb)
PLEP: 121946500(camk1gb) 121953780(camk1b) 121958505(camk1a) 121961709(camk1da)
SLUC: 116034593 116041504(camk1a) 116043671(camk1gb) 116054520(camk1da) 116067251(camk1b)
ECRA: 117938637(camk1da) 117943322(camk1b) 117943447 117943674(camk1a) 117947373(camk1gb)
GAT: 120817663(camk1da) 120829290(camk1gb) 120834852 120834952(camk1a) 120835087(camk1b)
MSAM: 119885780 119885945(camk1b) 119886713 119886980(camk1a) 119893678(camk1db) 119905368(camk1gb) 119918027(camk1da)
CUD: 121505406(camk1da) 121507029(camk1a) 121507387(camk1b) 121507445 121517777(camk1gb)
OAU: 116315133 116317023(camk1da) 116322025(camk1gb) 116326430(camk1b) 116332692(camk1db) 116334276(camk1a)
OML: 112138283(camk1da) 112140784(camk1b) 112144580 112145308(camk1a) 112158636(camk1gb)
CTUL: 119772191(camk1a) 119772597 119777201(camk1gb) 119791797(camk1b) 119794464(camk1da)
KMR: 108230168(camk1db) 108231113(camk1a) 108237591(camk1gb) 108240302 108246868(camk1b)
XGL: 120782953(camk1b) 120782988(camk1ga) 120793512 120800928(camk1da) 120803333(camk1gb) 120807585(camk1a)
LOC: 102689592 102698535(camk1g)
LCM: 102345889(CAMK1G) 102359609(CAMK1) 102361238 102363016
RTP: 109921423 109927166(camk1g)
BFO: 118415633
SCLV: 120327560
SPU: 115929968
APLC: 110974135
DME: Dmel_CG1495(CaMKI)
DER: 6555811
DSE: 6619459
DYA: Dyak_GE14549(Dyak_CaMKI)
DAN: 6505454
DSR: 110185403
DPE: 6601985
DMN: 108164452
DWI: 6651588
DAZ: 108617817
DNV: 108657892
DHE: 111598003
DVI: 6636211
MDE: 101897628
LCQ: 111687884
ACOZ: 120952575
AARA: 120896489
AAG: 5574828
AME: 727249
ACER: 108002457
BIM: 100746179
BTER: 100650648
CCAL: 108627871
OBB: 114875205
MGEN: 117222163
NMEA: 116426800
CGIG: 122396206
SOC: 105202459
MPHA: 105828833
AEC: 105147543
ACEP: 105623159
PBAR: 105429310
VEM: 105558067
HST: 105184682
DQU: 106747132
CFO: 105251255
FEX: 115242022
LHU: 105679119
PGC: 109859159
OBO: 105276910
PCF: 106788434
NVI: 100117454
CSOL: 105366428
MDL: 103576517
TCA: 656309
DPA: 109537170
ATD: 109603143
AGB: 108916967
APLN: 108740626
PPYR: 116165479
OTU: 111425218
BMOR: 101744568
BMAN: 114248676
MSEX: 115440457
BANY: 112044948
PMAC: 106714845
PPOT: 106106686
PXU: 106127412
PRAP: 110994409
ZCE: 119834717
HAW: 110370715
PXY: 105382968
API: 100166878
DNX: 107163193
AGS: 114131970
RMD: 113559447
BTAB: 109043989
DCI: 103514148
CLEC: 106666893
ZNE: 110828896
CSEC: 111873203
PVM: 113818271
HAME: 121861799
DSV: 119431339
RSAN: 119371857
RMP: 119163839
VDE: 111250454
VJA: 111271067
DPTE: 113796739
CSCU: 111614110
PTEP: 107443193
SDM: 118198623
CEL: CELE_K07A9.2(cmk-1)
CBR: CBG08406(Cbr-cmk-1)
BMY: BM_BM4856(Bma-cmk-1)
PCAN: 112571965
BGT: 106070996
CRG: 105340286
MYI: 110442509
PMAX: 117330854
OBI: 106883616
LAK: 106161880
NVE: 5507688
EPA: 110243356
HMG: 100200289
AQU: 100635387
ALY: 9328529
BRP: 103871608
BNA: 106346315
RSZ: 108812872
THJ: 104821293
CPAP: 110811562
CIT: 102609528
TCC: 18600079
GAB: 108470878
DZI: 111297144
GMX: 547731(PPCK4)
GSJ: 114369975
APRC: 113872832
RCN: 112199897
PMUM: 103324100
PAVI: 110748998
PDUL: 117614040
ZJU: 107412304
MNT: 21404279
BHJ: 120087180
JRE: 108991068
QLO: 115995170
VVI: 100252772
VRI: 117915446
SLY: 101251924 543865(PPCK2)
NTO: 104096632
NAU: 109239066
ITR: 116002590
OEU: 111371229
EGT: 105963041
LSV: 111905242
DCR: 108205258
BVG: 104887944
NNU: 104600864
PDA: 103708439
EGU: 105036875
PEQ: 110023763
AOF: 109826774
ATR: 18995834
PPP: 112274128
SCE: YFR014C(CMK1) YOL016C(CMK2)
ERC: Ecym_1275
KMX: KLMA_30371(CMK2)
NCS: NCAS_0A08880(NCAS0A08880) NCAS_0D00630(NCAS0D00630)
NDI: NDAI_0G05300(NDAI0G05300) NDAI_0H03520(NDAI0H03520)
TPF: TPHA_0O01120(TPHA0O01120)
TBL: TBLA_0D05010(TBLA0D05010)
TDL: TDEL_0B06320(TDEL0B06320)
KAF: KAFR_0C04480(KAFR0C04480) KAFR_0I02010(KAFR0I02010)
SLB: AWJ20_1666(CMK1) AWJ20_462(CMK2)
NCR: NCU02283(camk-2) NCU09123(camk-1)
NTE: NEUTE1DRAFT131368(NEUTE1DRAFT_131368) NEUTE1DRAFT96707(NEUTE1DRAFT_96707)
SMP: SMAC_04619(putative mek1) SMAC_05321 SMAC_08748
BFU: BCIN_02g08090(Bccmk2) BCIN_07g04730(Bccmk1)
ANG: ANI_1_432144(An16g03050) ANI_1_762024(An02g05490)
PBL: PAAG_05737 PAAG_12393(PAAG_07400)
SPO: SPACUNK12.02c(cmk1)
ABP: AGABI1DRAFT114778(AGABI1DRAFT_114778) AGABI1DRAFT130175(AGABI1DRAFT_130175)
ABV: AGABI2DRAFT120968(AGABI2DRAFT_120968) AGABI2DRAFT194968(AGABI2DRAFT_194968) AGABI2DRAFT229785(AGABI2DRAFT_229785)
EHI: EHI_137980(70.t00038)
PCB: PCHAS_145570(PC001103.02.0)
PTM: GSPATT00001873001 GSPATT00002068001 GSPATT00002078001 GSPATT00002107001 GSPATT00002108001 GSPATT00002182001 GSPATT00002682001 GSPATT00003198001 GSPATT00004205001 GSPATT00004609001 GSPATT00004610001 GSPATT00005003001 GSPATT00005243001 GSPATT00005284001 GSPATT00005326001 GSPATT00006526001 GSPATT00006575001 GSPATT00006748001 GSPATT00006928001 GSPATT00007295001 GSPATT00009828001 GSPATT00009969001 GSPATT00010264001 GSPATT00010852001 GSPATT00010951001 GSPATT00012351001 GSPATT00012852001 GSPATT00012859001 GSPATT00012868001 GSPATT00013165001 GSPATT00013272001 GSPATT00013913001 GSPATT00014152001 GSPATT00014433001 GSPATT00015382001 GSPATT00015640001 GSPATT00015989001 GSPATT00016461001 GSPATT00016715001 GSPATT00017038001 GSPATT00017662001 GSPATT00017992001 GSPATT00020106001 GSPATT00020280001 GSPATT00020354001 GSPATT00020607001 GSPATT00021127001 GSPATT00021737001 GSPATT00022205001 GSPATT00023034001 GSPATT00023417001 GSPATT00023576001 GSPATT00023613001 GSPATT00025450001 GSPATT00025565001 GSPATT00026169001 GSPATT00027257001 GSPATT00027933001 GSPATT00028082001 GSPATT00028265001 GSPATT00028690001 GSPATT00028854001 GSPATT00029444001 GSPATT00029823001 GSPATT00030806001 GSPATT00030851001 GSPATT00031441001 GSPATT00033469001 GSPATT00034463001 GSPATT00034603001 GSPATT00034657001 GSPATT00035283001 GSPATT00035344001 GSPATT00035435001 GSPATT00036520001 GSPATT00036521001 GSPATT00037053001 GSPATT00037311001 GSPATT00037368001 GSPATT00037451001 GSPATT00037471001 GSPATT00037488001 GSPATT00038896001 GSPATT00038897001 GSPATT00039596001 GSPATT00039617001
SMIN: v1.2.000312.t1(symbB.v1.2.000312.t1) v1.2.001934.t1(symbB.v1.2.001934.t1) v1.2.004464.t1(symbB.v1.2.004464.t1) v1.2.004554.t1(symbB.v1.2.004554.t1) v1.2.005177.t1(symbB.v1.2.005177.t1) v1.2.011705.t1(symbB.v1.2.011705.t1) v1.2.016514.t1(symbB.v1.2.016514.t1) v1.2.026377.t1(symbB.v1.2.026377.t1) v1.2.029723.t1(symbB.v1.2.029723.t1) v1.2.040251.t1(symbB.v1.2.040251.t1)
PTI: PHATRDRAFT_54265(CaMK2)
TPS: THAPSDRAFT_24056(MLK1)
 » show all
Reference
PMID:7641687
  Authors
Haribabu B, Hook SS, Selbert MA, Goldstein EG, Tomhave ED, Edelman AM, Snyderman R, Means AR
  Title
Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase.
  Journal
EMBO J 14:3679-86 (1995)
DOI:10.1002/j.1460-2075.1995.tb00037.x
  Sequence
[hsa:8536]
LinkDB

KEGG   ORTHOLOGY: K04515
Entry
K04515                      KO                                     

Name
CAMK2
Definition
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Pathway
map04012  ErbB signaling pathway
map04020  Calcium signaling pathway
map04024  cAMP signaling pathway
map04066  HIF-1 signaling pathway
map04114  Oocyte meiosis
map04217  Necroptosis
map04261  Adrenergic signaling in cardiomyocytes
map04310  Wnt signaling pathway
map04360  Axon guidance
map04713  Circadian entrainment
map04720  Long-term potentiation
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04728  Dopaminergic synapse
map04740  Olfactory transduction
map04745  Phototransduction - fly
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04916  Melanogenesis
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04925  Aldosterone synthesis and secretion
map04934  Cushing syndrome
map04971  Gastric acid secretion
map05012  Parkinson disease
map05022  Pathways of neurodegeneration - multiple diseases
map05031  Amphetamine addiction
map05152  Tuberculosis
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05214  Glioma
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
Disease
H00768  Autosomal recessive mental retardation
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04310 Wnt signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04066 HIF-1 signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04020 Calcium signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04024 cAMP signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04217 Necroptosis
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04922 Glucagon signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04912 GnRH signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04921 Oxytocin signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04916 Melanogenesis
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04925 Aldosterone synthesis and secretion
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09154 Digestive system
   04971 Gastric acid secretion
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09156 Nervous system
   04725 Cholinergic synapse
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04728 Dopaminergic synapse
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04720 Long-term potentiation
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04722 Neurotrophin signaling pathway
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09157 Sensory system
   04745 Phototransduction - fly
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04740 Olfactory transduction
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   04750 Inflammatory mediator regulation of TRP channels
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09158 Development and regeneration
   04360 Axon guidance
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   05205 Proteoglycans in cancer
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09162 Cancer: specific types
   05214 Glioma
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   05022 Pathways of neurodegeneration - multiple diseases
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09165 Substance dependence
   05031 Amphetamine addiction
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
   05415 Diabetic cardiomyopathy
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II
Other DBs
GO: 0004683
Genes
HSA: 815(CAMK2A) 816(CAMK2B) 817(CAMK2D) 818(CAMK2G)
PTR: 461445(CAMK2D) 462189(CAMK2A) 738167(CAMK2B) 738330(CAMK2G)
PPS: 100973727(CAMK2A) 100982179(CAMK2G) 100983859(CAMK2D) 100986246(CAMK2B)
GGO: 101134676(CAMK2D) 101136547(CAMK2G) 101148194(CAMK2B) 101153594(CAMK2A)
PON: 100172212(CAMK2A) 100433531(CAMK2B) 100436747(CAMK2D) 100462386(CAMK2G)
NLE: 100580290(CAMK2D) 100591995(CAMK2B) 100597007(CAMK2G) 100600165(CAMK2A)
MCC: 702504(CAMK2D) 705980(CAMK2G) 706977(CAMK2B) 710540(CAMK2A)
MCF: 101865637(CAMK2G) 101866326(CAMK2D) 101926613(CAMK2B) 102126681(CAMK2A)
CSAB: 103215984(CAMK2G) 103226136(CAMK2B) 103236144(CAMK2D) 103244792(CAMK2A)
CATY: 105571464(CAMK2D) 105589879(CAMK2A) 105596908(CAMK2B) 105597344(CAMK2G)
PANU: 101008925(CAMK2B) 101009984(CAMK2D) 101011087(CAMK2A) 101019885(CAMK2G) 116269450 116269451
RRO: 104669984(CAMK2G) 104670410(CAMK2A) 104671146(CAMK2B) 104676623(CAMK2D)
RBB: 108512486(CAMK2D) 108516884(CAMK2G) 108529387 108532044(CAMK2A) 108544005
TFN: 117065600(CAMK2A) 117073301(CAMK2B) 117081990(CAMK2G) 117085812(CAMK2D)
PTEH: 111537843(CAMK2G) 111547908(CAMK2D) 111552236(CAMK2B) 111552636(CAMK2A)
CJC: 100390938(CAMK2A) 100391424 100397956(CAMK2D) 100405903(CAMK2G) 100410352(CAMK2B)
SBQ: 101031635(CAMK2G) 101038342(CAMK2D) 101041452(CAMK2A) 101041781 101052251(CAMK2B)
MMUR: 105858406(CAMK2B) 105868864(CAMK2G) 105879489(CAMK2D) 105885735
MMU: 108058(Camk2d) 12322(Camk2a) 12323(Camk2b) 12325(Camk2g)
MCAL: 110284502(Camk2a) 110290827(Camk2d) 110305925(Camk2b) 110309790(Camk2g)
MPAH: 110320932(Camk2d) 110325574(Camk2g) 110331006(Camk2b) 110332832(Camk2a)
RNO: 171140(Camk2g) 24245(Camk2b) 24246(Camk2d) 25400(Camk2a)
MCOC: 116069264(Camk2b) 116084777(Camk2g) 116087223(Camk2a) 116093748(Camk2d)
MUN: 110546095(Camk2b) 110546686(Camk2a) 110551996(Camk2g) 110565513 110565514
CGE: 100752268 100763272(Camk2g) 100765253(Camk2a) 100769205(Camk2b)
PLEU: 114682227(Camk2d) 114693978(Camk2b) 114700207(Camk2g) 114707396(Camk2a)
NGI: 103734983(Camk2b) 103736933(Camk2g) 103743264(Camk2d) 103747079(Camk2a)
HGL: 101711305(Camk2d) 101713923(Camk2g) 101718749(Camk2b) 101722229(Camk2a)
OCU: 100101556(CAMK2G) 100101557(CAMK2D) 100341507(CAMK2A) 100342451(CAMK2B)
TUP: 102472689(CAMK2B) 102482912(CAMK2D) 102494625(CAMK2A) 102503259(CAMK2G)
CFA: 482687(CAMK2B) 489050(CAMK2G) 610764(CAMK2D) 612941(CAMK2A)
VVP: 112911701(CAMK2B) 112924513(CAMK2G) 112927337(CAMK2A) 112931026(CAMK2D)
VLG: 121486819(CAMK2G) 121487187(CAMK2A) 121489104(CAMK2B) 121493044(CAMK2D)
AML: 100466256(CAMK2D) 100474459(CAMK2G) 100475467(CAMK2A) 100478243(CAMK2B)
UMR: 103661761(CAMK2D) 103664598(CAMK2A) 103668027(CAMK2G) 103674683(CAMK2B)
UAH: 113255589(CAMK2D) 113257849(CAMK2B) 113259192(CAMK2G) 113263946(CAMK2A)
ORO: 101367567(CAMK2G) 101375584(CAMK2D) 101375944(CAMK2A) 101384300(CAMK2B)
MPUF: 101670702(CAMK2D) 101681123(CAMK2G) 101682911(CAMK2A) 101684734(CAMK2B)
EJU: 114202281(CAMK2B) 114211871 114211898(CAMK2A) 114214078(CAMK2G) 114222643(CAMK2D)
MLX: 118006598 118006728 118021697(CAMK2G) 118024497(CAMK2B) 118027107(CAMK2D)
FCA: 101084342(CAMK2A) 101098090(CAMK2G) 101098221(CAMK2D) 101098615(CAMK2B)
PTG: 102950197(CAMK2D) 102957556(CAMK2G) 102964851(CAMK2B) 102966494(CAMK2A)
PPAD: 109248360(CAMK2D) 109264424(CAMK2G) 109267916(CAMK2B) 109275954
AJU: 106968235(CAMK2B) 106970983(CAMK2G) 106977318(CAMK2D) 106985400(CAMK2A)
HHV: 120222252(CAMK2D) 120233726(CAMK2G) 120236563(CAMK2A) 120238899(CAMK2B)
BTA: 282162(CAMK2G) 525416(CAMK2B) 530719(CAMK2A) 532713(CAMK2D)
BOM: 102271451(CAMK2A) 102279381(CAMK2G) 102280002 102281822(CAMK2B)
BIU: 109553698(CAMK2G) 109557541(CAMK2B) 109560236(CAMK2D) 109562200(CAMK2A)
BBUB: 102389415(CAMK2G) 102396037(CAMK2B) 102397549(CAMK2A) 102416446(CAMK2D)
CHX: 102175934(CAMK2D) 102176762(CAMK2B) 102185084(CAMK2A) 102185715(CAMK2G)
OAS: 101108884(CAMK2G) 101113850(CAMK2D) 101118870(CAMK2B) 443453(CAMK2A)
ODA: 120861703(CAMK2D) 120863412(CAMK2A) 120865286(CAMK2G) 120877497(CAMK2B)
SSC: 100516166(CAMK2B) 100626014(CAMK2A) 397394(CAMK2G) 397674(CAMK2D)
CFR: 102506589(CAMK2B) 102512557(CAMK2A) 102521522(CAMK2D) 102522167(CAMK2G)
CDK: 105089916(CAMK2D) 105092345(CAMK2B) 105092453(CAMK2G) 105098484(CAMK2A)
BACU: 102999844(CAMK2G) 103003341(CAMK2B) 103012734(CAMK2D) 103018247(CAMK2A)
LVE: 103072903(CAMK2G) 103075213(CAMK2B) 103081366(CAMK2A) 103088458(CAMK2D)
OOR: 101269181(CAMK2D) 101271879(CAMK2A) 101281498(CAMK2G) 101287513(CAMK2B)
DLE: 111183091(CAMK2A) 111183530(CAMK2G) 111184516(CAMK2B) 111186068(CAMK2D)
PCAD: 102980540(CAMK2B) 102988954(CAMK2D) 102994812(CAMK2G) 102995187(CAMK2A)
ECB: 100064138(CAMK2G) 100071654(CAMK2A) 100072618(CAMK2D) 100146368(CAMK2B)
EPZ: 103549121(CAMK2A) 103549465(CAMK2G) 103549616(CAMK2D) 103554952(CAMK2B)
EAI: 106822866(CAMK2B) 106838495(CAMK2A) 106843233(CAMK2D) 106843543(CAMK2G)
MYB: 102252254(CAMK2D) 102257317(CAMK2A) 102260966(CAMK2B) 102262365(CAMK2G)
MYD: 102764742(CAMK2A) 102765684(CAMK2D) 102773049(CAMK2G)
MMYO: 118652970(CAMK2D) 118658714(CAMK2A) 118665863(CAMK2B) 118670159(CAMK2G)
MNA: 107527851(CAMK2D) 107535228(CAMK2A) 107542053(CAMK2B) 107545830(CAMK2G)
HAI: 109372542(CAMK2G) 109373019(CAMK2B) 109375001(CAMK2A) 109390284(CAMK2D)
DRO: 112305463(CAMK2G) 112306861(CAMK2B) 112312435(CAMK2D) 112319561(CAMK2A)
SHON: 118980016(CAMK2D) 118983461(CAMK2B) 118986155(CAMK2A) 118993496(CAMK2G)
AJM: 119037697(CAMK2D) 119038077(CAMK2G) 119052888(CAMK2B) 119061401(CAMK2A)
MMF: 118615118(CAMK2D) 118619531(CAMK2B) 118632270(CAMK2G) 118643618(CAMK2A)
PALE: 102880869(CAMK2D) 102888385(CAMK2A) 102888982(CAMK2B) 102896030(CAMK2G)
RAY: 107497167(CAMK2A) 107498266(CAMK2G) 107510894(CAMK2D) 107512385(CAMK2B)
MJV: 108385398(CAMK2A) 108394027(CAMK2B) 108398760(CAMK2G) 108400883
TOD: 119231251(CAMK2B) 119234396(CAMK2G) 119243267(CAMK2A) 119243611(CAMK2D)
LAV: 100653927(CAMK2G) 100658516(CAMK2B) 100663321(CAMK2D) 104846071(CAMK2A)
MDO: 100010898(CAMK2G) 100011784(CAMK2D) 100024521(CAMK2B) 100028973(CAMK2A)
SHR: 100913975(CAMK2D) 100916233(CAMK2G) 100918427(CAMK2B) 100934917(CAMK2A)
PCW: 110192850(CAMK2A) 110206572(CAMK2B) 110218623(CAMK2D) 110221437(CAMK2G)
OAA: 100074083(CAMK2D) 100079279(CAMK2A) 100089453(CAMK2G) 100089905(CAMK2B)
GGA: 374174(CAMK2B) 374175(CAMK2A) 422688(CAMK2D) 423737(CAMK2G)
PCOC: 116231255(CAMK2D) 116231328(CAMK2B) 116232152(CAMK2A) 116235083(CAMK2G)
MGP: 100541354(CAMK2D) 100541823(CAMK2G) 100546125(CAMK2B) 100550458(CAMK2A)
CJO: 107313595(CAMK2D) 107315812(CAMK2G) 107320147(CAMK2A) 107323605(CAMK2B)
NMEL: 110387161(CAMK2B) 110397346(CAMK2D) 110399309(CAMK2G) 110405364(CAMK2A)
APLA: 101801648(CAMK2D) 101802786 101804017(CAMK2G)
ACYG: 106032824(CAMK2A) 106033089(CAMK2G) 106038617(CAMK2D)
TGU: 100219415(CAMK2D) 100220435(CAMK2A) 100226008(CAMK2G) 100228031(CAMK2B)
LSR: 110471178(CAMK2D) 110478273(CAMK2B) 110480733(CAMK2G) 110482768(CAMK2A)
SCAN: 103813998(CAMK2G) 103815714(CAMK2D) 103817304(CAMK2A) 103822722(CAMK2B)
PMOA: 120498441(CAMK2A) 120502800(CAMK2D) 120505381(CAMK2B) 120510919(CAMK2G)
GFR: 102031855(CAMK2D) 102036854(CAMK2G) 102040653(CAMK2A) 102041076(CAMK2B)
FAB: 101806876(CAMK2D) 101810626(CAMK2A) 101812759(CAMK2G) 101817363(CAMK2B)
PHI: 102104310(CAMK2B) 102104633(CAMK2G) 102108054(CAMK2D) 102112061(CAMK2A)
PMAJ: 107203083(CAMK2D) 107206815(CAMK2G) 107210746(CAMK2A) 107213806
CCAE: 111928996(CAMK2D) 111931070(CAMK2G) 111935541(CAMK2A) 111945916
CCW: 104683185(CAMK2B) 104689694(CAMK2A) 104696844(CAMK2D) 104697948(CAMK2G)
ETL: 114058136(CAMK2G) 114063195(CAMK2A) 114069625(CAMK2D) 114071691(CAMK2B)
FPG: 101914593(CAMK2D) 101915367(CAMK2G) 101918953(CAMK2A) 101923748(CAMK2B)
FCH: 102051471(CAMK2D) 102052104(CAMK2A) 102057655(CAMK2G)
CLV: 102083707(CAMK2B) 102086515(CAMK2G) 102090258(CAMK2D) 102095946(CAMK2A)
EGZ: 104123272(CAMK2A) 104129105(CAMK2G) 104135961
NNI: 104014199(CAMK2A) 104016939(CAMK2G) 104019154(CAMK2D) 104022609(CAMK2B)
ACUN: 113479615(CAMK2D) 113481572(CAMK2G) 113485161(CAMK2A)
PADL: 103915611(CAMK2G) 103915821(CAMK2A) 103926125(CAMK2D)
AAM: 106491995(CAMK2D) 106493448(CAMK2A) 106494574(CAMK2B) 106498878(CAMK2G)
ASN: 102369083(CAMK2B) 102372048(CAMK2A) 102376749(CAMK2G) 102382581(CAMK2D)
AMJ: 102562159(CAMK2G) 102564631(CAMK2B) 102570318(CAMK2D) 106736808(CAMK2A)
CPOO: 109309367(CAMK2D) 109310164(CAMK2A) 109323865(CAMK2G)
GGN: 109287379(CAMK2G) 109289889(CAMK2A) 109301094(CAMK2D)
PSS: 102445881(CAMK2D) 102452528(CAMK2G) 102461772(CAMK2A)
CMY: 102932986(CAMK2B) 102935217(CAMK2D) 102935773(CAMK2G) 102938664(CAMK2A)
CPIC: 101933671(CAMK2B) 101939367(CAMK2A) 101952653(CAMK2D) 101952899(CAMK2G)
TST: 117872862(CAMK2B) 117877963(CAMK2D) 117880068(CAMK2G) 117881292(CAMK2A)
CABI: 116815119(CAMK2B) 116819953(CAMK2A) 116823615(CAMK2G) 116825358
ACS: 100552004(camk2d) 100554504(camk2b) 100562492(camk2g) 100563784(camk2a)
PVT: 110077789(CAMK2G) 110083899 110084335(CAMK2B) 110086082(CAMK2A)
PBI: 103054335(CAMK2A) 103062746(CAMK2B) 103063596 103065234(CAMK2G)
PMUR: 107286231(CAMK2B) 107286689(CAMK2D) 107290559 107293182
TSR: 106544195(CAMK2G) 106547696(CAMK2B) 106547763(CAMK2A) 106557171
PGUT: 117655220(CAMK2A) 117676103(CAMK2G) 117677048(CAMK2B) 117679961(CAMK2D)
PMUA: 114585935 114591346(CAMK2A) 114597036(CAMK2G) 114604777(CAMK2D)
ZVI: 118080422(CAMK2A) 118083949(CAMK2D) 118096405(CAMK2G) 118096835(CAMK2B)
GJA: 107110299 107117391(CAMK2B) 107122036 107123332(CAMK2A)
XLA: 108696257(camk2g.L) 108712641 380508(camk2g.S) 397789(camk2b.L) 398376(camk2d.L) 399160(camk2d.S) 399284(camk2a.S)
XTR: 100101771(camk2a) 100135023(camk2d) 100135711(camk2g) 780379(camk2b)
NPR: 108785601(CAMK2B) 108785806(CAMK2A) 108798063 108804479(CAMK2G)
DRE: 436815(camk2d2) 445208(camk2d1) 550436(camk2a) 562064(camk2b1) 791855(camk2g1) 793359(camk2g2) 798222(camk2b)
IPU: 108255499 108260541 108263497(camk2g) 108267517(camk2d1) 108273829 108277079(camk2b) 108278566(CAMK2A)
ELY: 117246069(camk2d1) 117247050 117248372 117252481(camk2b1) 117256057(camk2d2) 117265015(camk2a) 117269440
SLUC: 116040540(camk2d2) 116041821 116049824(camk2d1) 116054185(camk2b1) 116061519 116061713 116063584(camk2a)
ECRA: 117934611(camk2d1) 117935966(camk2d2) 117936435 117944565(camk2b1) 117959726 117960126(camk2g2)
GAT: 120819535 120820869(camk2g2) 120821702(camk2a) 120822206(camk2d1) 120825607
MSAM: 119891232(camk2b1) 119895357(camk2a) 119899100(camk2d2) 119912136(camk2d1) 119914912 119915852
CUD: 121504420(camk2d1) 121508869(camk2d2) 121509845(camk2b1) 121510861(camk2g2) 121518659(camk2a) 121524964 121528829
OML: 112136361(camk2b1) 112136908(camk2a) 112138354 112154180 112156501(camk2d1) 112156983(camk2d2) 112163512 118599716(camk2g2)
KMR: 108242787(camk2b1) 108244038(camk2g2) 108244269(camk2d1) 108245388 108246882(camk2d2) 108248045 108251493
XGL: 120793967 120796110(camk2g2) 120797123 120799709(camk2d2) 120802245(camk2a) 120805506(camk2b1) 120806100
LOC: 102691337(camk2g) 102693083(camk2d) 102696029(camk2b) 102697295
LCM: 102346458(CAMK2G) 102360076 102360263(CAMK2B) 102361646(CAMK2A)
CMK: 103180901(camk2d) 103181591(camk2g) 103188234(camk2a) 103190417
RTP: 109912036 109922295(camk2d)
BFO: 118411573
CIN: 100181678
SCLV: 120347288
APLC: 110977564
SKO: 100371971(CAMK2D)
DME: Dmel_CG18069(CaMKII)
DER: 6555827
DSE: 6620107
DSI: Dsimw501_GD28701(Dsim_GD28701)
DAN: 6505477
DSR: 110185473
DPE: 6602545
DMN: 108164456
DWI: 6651093
DAZ: 108617865
DNV: 108655409
DHE: 111598041
DVI: 6636205
MDE: 101888482
LCQ: 111680369
ACOZ: 120960639
AARA: 120906742
AAG: 5578710
AALB: 109428414
CPII: 120413704
AME: 551691(Camkii)
ACER: 108003363
BIM: 100745387
BTER: 100648089
CCAL: 108623622
OBB: 114880753
MGEN: 117226512
NMEA: 116432439
CGIG: 122396323
SOC: 105205626
AEC: 105148855
ACEP: 105625869
PBAR: 105433286
VEM: 105560165
HST: 105185279
DQU: 106742123
CFO: 105254953
FEX: 115244580
LHU: 105669204
PGC: 109859326
OBO: 105281406
PCF: 106784523
NVI: 100122555
CSOL: 105364037
MDL: 103575949
TCA: 655266
DPA: 109534487
ATD: 109596600
AGB: 108910834
NVL: 108561165
APLN: 108735342
PPYR: 116182037
OTU: 111423765
BMOR: 100462731(CaMKII)
BMAN: 114249291
MSEX: 115441060
BANY: 112043709
PMAC: 106715049
PPOT: 106105520
PXU: 106125387
PRAP: 110999070
ZCE: 119831057
HAW: 110375303
TNL: 113502491
PXY: 105391166
API: 100161639
DNX: 107171609
AGS: 114127462
RMD: 113556511
BTAB: 109043856
DCI: 103509280
CLEC: 106663853
NLU: 111048716
ZNE: 110832661
CSEC: 111869317
FCD: 110842877
HAME: 121868300
DSV: 119436648
RMP: 119184955
VDE: 111243562
VJA: 111270075
TUT: 107359488
DPTE: 113790681
CEL: CELE_K11E8.1(unc-43)
CBR: CBG04391(Cbr-unc-43)
TSP: Tsp_02594
PCAN: 112574878
BGT: 106077998
GAE: 121379310
CRG: 105341112
MYI: 110448224
PMAX: 117334343
OBI: 106874089
LAK: 106174951
EGL: EGR_06207
SPAR: SPRG_14823
 » show all
Reference
  Authors
Illario M, Cavallo AL, Bayer KU, Di Matola T, Fenzi G, Rossi G, Vitale M
  Title
Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation.
  Journal
J Biol Chem 278:45101-8 (2003)
DOI:10.1074/jbc.M305355200
  Sequence
[hsa:815]
Reference
PMID:2543961
  Authors
Hanley RM, Payne ME, Cruzalegui F, Christenson MA, Means AR
  Title
Sequence of the cDNA for the alpha subunit of calmodulin kinase II from mouse brain.
  Journal
Nucleic Acids Res 17:3992 (1989)
DOI:10.1093/nar/17.10.3992
  Sequence
[mmu:12322]
LinkDB

KEGG   ORTHOLOGY: K05869
Entry
K05869                      KO                                     

Name
CAMK4
Definition
calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
Pathway
map04020  Calcium signaling pathway
map04024  cAMP signaling pathway
map04211  Longevity regulating pathway
map04371  Apelin signaling pathway
map04380  Osteoclast differentiation
map04720  Long-term potentiation
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04921  Oxytocin signaling pathway
map04925  Aldosterone synthesis and secretion
map05031  Amphetamine addiction
map05034  Alcoholism
map05214  Glioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04020 Calcium signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04024 cAMP signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04925 Aldosterone synthesis and secretion
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09156 Nervous system
   04725 Cholinergic synapse
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04720 Long-term potentiation
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04722 Neurotrophin signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09149 Aging
   04211 Longevity regulating pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
 09160 Human Diseases
  09162 Cancer: specific types
   05214 Glioma
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09165 Substance dependence
   05031 Amphetamine addiction
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   05034 Alcoholism
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  CAMK1 family [OT]
   K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
Other DBs
GO: 0004683
Genes
HSA: 814(CAMK4)
PTR: 461992(CAMK4)
PPS: 100970371(CAMK4)
GGO: 101140371(CAMK4)
PON: 100461605(CAMK4)
NLE: 100583900(CAMK4)
MCC: 712322(CAMK4)
MCF: 101864901(CAMK4)
CSAB: 103244326(CAMK4)
CATY: 105576638(CAMK4)
PANU: 101009081(CAMK4)
RRO: 104677657(CAMK4)
RBB: 108540302(CAMK4)
TFN: 117064830(CAMK4)
PTEH: 111542684(CAMK4)
CJC: 100388410(CAMK4)
SBQ: 101053463(CAMK4)
MMUR: 105865738(CAMK4)
MMU: 12326(Camk4)
MCAL: 110284636(Camk4)
MPAH: 110333240(Camk4)
RNO: 25050(Camk4)
MCOC: 116086957(Camk4)
MUN: 110564828(Camk4)
CGE: 100774010(Camk4)
PLEU: 114691636(Camk4)
NGI: 103752296(Camk4)
HGL: 101700365(Camk4)
CCAN: 109696025(Camk4)
OCU: 103345118(CAMK4)
TUP: 102479520(CAMK4)
CFA: 100684140(CAMK4)
VVP: 112915439(CAMK4)
VLG: 121489316(CAMK4)
AML: 100473015(CAMK4)
UMR: 103675811(CAMK4)
UAH: 113254999(CAMK4)
ORO: 101369425(CAMK4)
ELK: 111148267
MPUF: 101677801(CAMK4)
EJU: 114208735(CAMK4)
MLX: 118017609(CAMK4)
FCA: 101095400(CAMK4)
PTG: 102954895(CAMK4)
PPAD: 109267609(CAMK4)
AJU: 106975674(CAMK4)
HHV: 120224722(CAMK4)
BTA: 100337083(CAMK4)
BOM: 102264521(CAMK4)
BBUB: 102389738(CAMK4)
CHX: 102187484(CAMK4)
OAS: 101108308(CAMK4)
ODA: 120863455(CAMK4)
SSC: 100515364(CAMK4)
CFR: 102503715(CAMK4)
CDK: 105095388(CAMK4)
BACU: 102998672(CAMK4)
LVE: 103081119(CAMK4)
OOR: 101273696(CAMK4)
DLE: 111183716(CAMK4)
PCAD: 102984487(CAMK4)
ECB: 100073192(CAMK4)
EPZ: 103550069(CAMK4)
EAI: 106832342(CAMK4)
MYB: 102254489(CAMK4)
MYD: 102761359(CAMK4)
MMYO: 118656630(CAMK4)
MNA: 107546482(CAMK4)
HAI: 109391534(CAMK4)
DRO: 112307173(CAMK4)
SHON: 118977337(CAMK4)
AJM: 119065119(CAMK4)
MMF: 118641608(CAMK4)
PALE: 102879333(CAMK4)
RAY: 107506545(CAMK4)
MJV: 108390709(CAMK4)
TOD: 119260183(CAMK4)
LAV: 100671333(CAMK4)
TMU: 101343253
MDO: 100015956(CAMK4)
SHR: 100920792(CAMK4)
PCW: 110222132(CAMK4)
OAA: 100076517 100082421(CAMK4)
GGA: 427267(CAMK4L) 723973(CAMK4)
PCOC: 116235788 116239726(CAMK4)
MGP: 100551031(CAMK4)
CJO: 107306359(CAMK4) 107325456
NMEL: 110388918 110389600(CAMK4)
APLA: 101802471(CAMK4) 101804940
ACYG: 106042351(CAMK4) 106048195
TGU: 100219262(CAMK4)
LSR: 110467596(CAMK4) 110480196
SCAN: 103822052 103824116(CAMK4)
PMOA: 120513733(CAMK4) 120513887
GFR: 102038357 102040809(CAMK4)
FAB: 101810211(CAMK4) 101818551
PHI: 102112643 102114009(CAMK4)
PMAJ: 107215374 107216227(CAMK4)
CCAE: 111940603(CAMK4) 111944618
CCW: 104693208(CAMK4) 104697064
ETL: 114054669(CAMK4) 114066382
FPG: 101913113(CAMK4) 101917352
FCH: 102050248(CAMK4) 102054662
CLV: 102093272 102098059(CAMK4)
EGZ: 104128295 104135038(CAMK4)
NNI: 104022203(CAMK4)
ACUN: 113489308 113489531(CAMK4)
PADL: 103920872(CAMK4)
ASN: 102370467(CAMK4) 102377785
AMJ: 102566359(CAMK4) 102571105
CPOO: 109308169(CAMK4) 109312309
GGN: 109294946 109298085(CAMK4)
PSS: 102460870(CAMK4)
CMY: 102942278 102943759(CAMK4)
CPIC: 101930944 101933258(CAMK4)
TST: 117869013 117879161(CAMK4)
ACS: 100559276(camk4) 100564355
PVT: 110072022(CAMK4) 110072612
TSR: 106553245(CAMK4)
PGUT: 117668620 117674636(CAMK4)
PMUA: 114588515 114606108(CAMK4)
ZVI: 118077001(CAMK4) 118086017
XLA: 108707217(camk4.S) 108712576 373837(camk4.L)
XTR: 100490912(camk4) 100496389
NPR: 108792885(CAMK4) 108793483
DRE: 550270(camk4)
CCAR: 109053483 109108254(camk4)
IPU: 108260461(camk4)
PHYP: 113531350(camk4) 113546396
AMEX: 103044753(camk4)
EEE: 113586933(camk4)
TRU: 101066536(camk4)
NCC: 104962492
ELY: 117253336(si:ch73-60h1.1)
PLEP: 121939058
SLUC: 116059162(si:ch73-60h1.1)
PFLV: 114561522(camk4)
GAT: 120823668(si:ch73-60h1.1)
MSAM: 119888480 119888860(si:ch73-60h1.1)
CUD: 121512456(si:ch73-60h1.1)
OAU: 116333055(si:ch73-60h1.1)
OLA: 101155594
OML: 112150356(si:ch73-60h1.1)
XCO: 114150793
XHE: 116725306(camk4)
PRET: 103463153
CVG: 107103959(camk4)
CTUL: 119784688(si:ch73-60h1.1)
NFU: 107393094
KMR: 108248674(si:ch73-60h1.1)
ALIM: 106531135(camk4)
AOCE: 111575981(camk4)
CSEM: 103399037(camk4)
POV: 109644251
LCF: 108891760(camk4)
SDU: 111231823
XGL: 120790665(si:ch73-60h1.1)
HCQ: 109506827(camk4)
BPEC: 110162797
MALB: 109965258(camk4)
ELS: 105011406 105027933(camk4)
SFM: 108925114(camk4) 108930508
PKI: 111836089(camk4) 111844630
LOC: 102690113(camk4)
LCM: 102362167(CAMK4)
CMK: 103181151(camk4) 103182089
BFO: 118408272
CIN: 100176025
SCLV: 120334047
SPU: 592450
APLC: 110988799
SKO: 100373179
NLU: 111053087
ZNE: 110829799
CSEC: 111863842
FCD: 110859869
PCAN: 112554592
GAE: 121382235
PMAX: 117333954
OBI: 106870421
LAK: 106159758
EPA: 110250062
ADF: 107345984
AMIL: 114959403
SPIS: 111321760
DGT: 114534474
HMG: 100213537
 » show all
Reference
PMID:8065343
  Authors
Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS
  Title
Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.
  Journal
Mol Cell Biol 14:6107-16 (1994)
DOI:10.1128/MCB.14.9.6107
  Sequence
[rno:25050]
Reference
PMID:8107230
  Authors
Mosialos G, Hanissian SH, Jawahar S, Vara L, Kieff E, Chatila TA
  Title
A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1.
  Journal
J Virol 68:1697-705 (1994)
DOI:10.1128/JVI.68.3.1697-1705.1994
  Sequence
[hsa:814]
LinkDB

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