KEGG   ORTHOLOGY: K08803
Entry
K08803                      KO                                     

Name
DAPK
Definition
death-associated protein kinase [EC:2.7.11.1]
Pathway
ko04140  Autophagy - animal
ko05200  Pathways in cancer
ko05219  Bladder cancer
Disease
H00022  Bladder cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K08803  DAPK; death-associated protein kinase
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08803  DAPK; death-associated protein kinase
  09162 Cancer: specific types
   05219 Bladder cancer
    K08803  DAPK; death-associated protein kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08803  DAPK; death-associated protein kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08803  DAPK; death-associated protein kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  DAPK family
   K08803  DAPK; death-associated protein kinase
Genes
HSA: 1612(DAPK1) 1613(DAPK3) 23604(DAPK2)
PTR: 455594(DAPK3) 464571(DAPK1) 747631(DAPK2)
PPS: 100972913(DAPK2) 100986472(DAPK1) 100993947(DAPK3)
GGO: 101125817(DAPK3) 101148094(DAPK1) 101151055(DAPK2) 115935778
PON: 100440287(DAPK3) 100448934(DAPK1) 100455827(DAPK2)
NLE: 100590142(DAPK3) 100598470(DAPK2) 100603623(DAPK1)
MCC: 694315(DAPK1) 706421(DAPK2) 714221(DAPK3)
MCF: 102114785(DAPK1) 102133584(DAPK2) 102138834(DAPK3)
CSAB: 103219698(DAPK1) 103233720(DAPK3) 103245501 103245502(DAPK2)
CATY: 105584264(DAPK1) 105591887(DAPK3) 105601038(DAPK2)
PANU: 101000600(DAPK3) 101016019(DAPK1) 101021037(DAPK2)
RRO: 104655916(DAPK2) 104665431(DAPK3) 104673712(DAPK1)
RBB: 108512089(DAPK3) 108521155(DAPK1) 108537489(DAPK2)
TFN: 117070531(DAPK2) 117075779(DAPK3) 117098396(DAPK1)
CJC: 100389223(DAPK1) 100392899(DAPK3) 100400671(DAPK2)
SBQ: 101029536(DAPK1) 101036686(DAPK3) 101043395(DAPK2)
MMUR: 105855614(DAPK1) 105868109(DAPK2) 105873943(DAPK3)
MMU: 13143(Dapk2) 13144(Dapk3) 69635(Dapk1)
MCAL: 110301682(Dapk2) 110303111(Dapk3) 110307645(Dapk1)
MPAH: 110326479(Dapk3) 110327965(Dapk2) 110334143(Dapk1)
RNO: 306722(Dapk1) 64391(Dapk3)
MCOC: 116072163(Dapk2) 116076180(Dapk3) 116082387(Dapk1)
MUN: 110552706(Dapk2) 110555608(Dapk3) 110556598(Dapk1)
CGE: 100766355(Dapk1) 100773012(Dapk2) 100773624(Dapk3)
PLEU: 114688122(Dapk3) 114691151(Dapk2) 114709708(Dapk1)
NGI: 103734199(Dapk1) 103737271(Dapk3) 103750086(Dapk2)
HGL: 101708121(Dapk2) 101716355(Dapk3) 101723905(Dapk1)
CCAN: 109676827(Dapk2) 109676841 109687804(Dapk3) 109687921(Dapk1)
OCU: 100343775(DAPK1) 100352862(DAPK2)
TUP: 102480476(DAPK2) 102495895(DAPK1) 106734235(DAPK3)
CFA: 476745(DAPK3) 484142(DAPK1) 610682(DAPK2)
VVP: 112908665(DAPK1) 112924202(DAPK2) 112935560(DAPK3)
VLG: 121483960(DAPK1) 121484328(DAPK2) 121495761(DAPK3)
AML: 100471255(DAPK2) 100471455(DAPK3) 100476424(DAPK1)
UMR: 103679099(DAPK2) 103681831(DAPK3) 103682208(DAPK1)
UAH: 113240841(DAPK2) 113242818(DAPK3) 113249736 113269788(DAPK1)
ORO: 101365336(DAPK1) 101375783(DAPK2) 101377929(DAPK3)
MPUF: 101676683(DAPK3) 101679190(DAPK2) 101682361(DAPK1)
EJU: 114203450 114206328(DAPK2) 114223366(DAPK1) 114226295(DAPK3)
MLX: 118002939(DAPK2) 118005027(DAPK3) 118023358(DAPK1)
FCA: 101084322(DAPK1) 101089774(DAPK2) 101099780(DAPK3)
PTG: 102951891(DAPK1) 102961109(DAPK2)
PPAD: 109251682(DAPK1) 109255861(DAPK3) 109262871(DAPK2)
AJU: 106971447(DAPK1) 106987289(DAPK2) 113596415(DAPK3)
HHV: 120221968(DAPK2) 120224184(DAPK1) 120242110(DAPK3)
BTA: 525506(DAPK3) 529131(DAPK2) 540873(DAPK1)
BOM: 102268782(DAPK1) 102270869(DAPK3) 102285056(DAPK2)
BIU: 109561757(DAPK3) 109563229(DAPK1) 109565051(DAPK2)
BBUB: 102403046(DAPK3) 102410104(DAPK2) 102415203(DAPK1)
CHX: 102169967(DAPK2) 102176318(DAPK3) 102185182(DAPK1)
OAS: 101113985(DAPK1) 101114352(DAPK3) 101123304(DAPK2)
ODA: 120853080(DAPK2) 120864818(DAPK3) 120866974(DAPK1)
SSC: 100155578(DAPK2) 100516103(DAPK1) 100624415(DAPK3)
CFR: 102506911(DAPK2) 102510747(DAPK3) 102512779(DAPK1)
CDK: 105084696(DAPK1) 105100519(DAPK2) 105105298(DAPK3)
BACU: 102997342(DAPK2) 103001915(DAPK1) 103019434(DAPK3)
LVE: 103084290(DAPK2) 103084641(DAPK1) 103089714(DAPK3)
OOR: 101285964(DAPK3) 101286241(DAPK1) 101288070(DAPK2)
DLE: 111166101(DAPK3) 111166847(DAPK1) 111177698(DAPK2)
PCAD: 102984261(DAPK1) 102991616(DAPK2) 102993215(DAPK3)
ECB: 100061244(DAPK3) 100061567(DAPK1) 100066921(DAPK2)
EPZ: 103543889(DAPK3) 103550839(DAPK1) 103555440(DAPK2)
EAI: 106822011(DAPK1) 106832364(DAPK3) 106837203(DAPK2)
MYB: 102244790(DAPK2) 102253738(DAPK3) 102259903(DAPK1)
MYD: 102755770(DAPK2) 102755828(DAPK1) 102766010(DAPK3)
MMYO: 118653501(DAPK2) 118658400(DAPK3) 118667408
MNA: 107525638(DAPK3) 107533767(DAPK2) 107544922(DAPK1)
HAI: 109371518(DAPK1) 109387099(DAPK2) 109388629(DAPK3)
DRO: 112304334(DAPK1) 112311854(DAPK2) 112312562(DAPK3)
SHON: 118979840(DAPK1) 118984501(DAPK3) 118992293(DAPK2)
AJM: 119056948(DAPK2) 119060019(DAPK1) 119063781(DAPK3)
MMF: 118615968(DAPK3) 118618295(DAPK2) 118629493(DAPK1)
PALE: 102885201(DAPK2) 102891860(DAPK1) 102892714(DAPK3)
RAY: 107502752(DAPK1) 107508986(DAPK2) 107520126(DAPK3)
MJV: 108387302(DAPK1) 108388881(DAPK3) 108392801(DAPK2)
LAV: 100669221(DAPK2) 100669366(DAPK1) 100670001(DAPK3)
MDO: 100012765(DAPK1) 100013020 100022106(DAPK3) 100023465(DAPK2) 100023666
SHR: 100914009(DAPK3) 100916127 100933287(DAPK1) 100934384(DAPK2)
PCW: 110197467(DAPK3) 110197634(DAPK1) 110206483(DAPK2)
OAA: 100085320(DAPK2) 100087379(DAPK1) 100087757(DAPK3) 103169903
GGA: 100857512 100857587(DAPK2) 101748881(DAPK3) 431670(DAPK1)
PCOC: 116232291(DAPK1) 116236124(DAPK3) 116237292 116244600(DAPK2)
MGP: 100538641(DAPK2) 100540942 104914685(DAPK3) 104915115(DAPK1)
CJO: 107306266(DAPK1) 107318543(DAPK2) 107324421 107325526(DAPK3)
NMEL: 110387943 110389010(DAPK3) 110389546(DAPK1) 110403983(DAPK2)
APLA: 101792822(DAPK3) 101802579(DAPK2) 101803493(DAPK1)
ACYG: 106033767(DAPK2) 106044954(DAPK3) 106045379(DAPK1)
TGU: 100223134(DAPK2) 100231489(DAPK1) 101232831(DAPK3) 115498461
LSR: 110471007(DAPK1) 110471576 110478463(DAPK3) 110479829(DAPK2)
SCAN: 103822967(DAPK1) 103823157(DAPK2) 103824535(DAPK3) 103824822
PMOA: 120498904 120499030(DAPK3) 120512052(DAPK1) 120512823(DAPK2)
GFR: 102031539(DAPK2) 102033291(DAPK1) 102039107(DAPK3) 102039381
FAB: 101810508 101810950(DAPK2) 101814061(DAPK3) 101814976(DAPK1)
PHI: 102099507(DAPK1) 102102679(DAPK2) 102103034(DAPK3)
PMAJ: 107209228(DAPK2) 107215467(DAPK3) 107216363(DAPK1)
CCAE: 111934226(DAPK2) 111940420(DAPK3) 111941795(DAPK1)
CCW: 104683791(DAPK2) 104692031(DAPK1) 104697377(DAPK3)
ETL: 114056007(DAPK1) 114070936(DAPK3) 114071781(DAPK2)
FPG: 101911063(DAPK2) 101918882(DAPK3) 101919670(DAPK1) 101920474
FCH: 102045949 102056191(DAPK2) 102056328(DAPK1) 102058307(DAPK3)
CLV: 102092003(DAPK1) 102094499(DAPK3) 102095370(DAPK2)
EGZ: 104124348(DAPK3) 104126015(DAPK1) 104130747(DAPK2)
NNI: 104011763(DAPK1) 104012073 104016745(DAPK2) 104018759(DAPK3)
ACUN: 113483884(DAPK2) 113489514(DAPK3) 113489956(DAPK1)
PADL: 103920451(DAPK1) 103921995(DAPK2)
AAM: 106489414(DAPK1) 106492201(DAPK3) 106496426(DAPK2)
ASN: 102375841(DAPK3) 102382177 102383363(DAPK2) 102388079(DAPK1)
AMJ: 102557650(DAPK2) 102559675(DAPK3) 102567368(DAPK1) 102568891
CPOO: 109308750(DAPK2) 109323539(DAPK1) 109324012 109324872(DAPK3)
GGN: 109288699(DAPK2) 109294856(DAPK3) 109297544(DAPK1) 109298907
PSS: 102444343(DAPK1) 102451247(DAPK2) 102454427(DAPK3) 102460485
CMY: 102932262(DAPK3) 102934441(DAPK2) 102934761(DAPK1) 102939739
CPIC: 101940134(DAPK3) 101945034(DAPK1) 101952656
TST: 117868874(DAPK3) 117869496 117879112(DAPK1) 117883637(DAPK2)
CABI: 116815045(DAPK3) 116815057(DAPK2) 116831803 116837941(DAPK1)
ACS: 100553877 100556297(dapk1)
PVT: 110072459(DAPK3) 110074519(DAPK2) 110081510 110085545(DAPK1)
PBI: 103051240(DAPK3) 103054909(DAPK1) 103059307(DAPK2) 103062088
PMUR: 107283171(DAPK2) 107297063(DAPK3) 107297726(DAPK1) 107299393 107299395
PGUT: 117658375 117660956(DAPK2) 117661376(DAPK1) 117670108
PMUA: 114584472(DAPK2) 114586945 114588477 114588560(DAPK3) 114606903(DAPK1)
ZVI: 118076703(DAPK1) 118087548(DAPK3) 118092632(DAPK2)
GJA: 107118016(DAPK2) 107118242(DAPK3) 107119724(DAPK1)
XLA: 108700356 108705106 108711286 108712999 431807(dapk1.S) 432161(dapk3.S) 446562(dapk1.L) 496293(dapk2.L) 734514(dapk3.L)
XTR: 100144678(dapk1) 100145135(dapk2) 101732277 407849(nek2) 549766(dapk3)
NPR: 108784035(DAPK2) 108788145(DAPK1) 108789624(DAPK3) 108803670
DRE: 555536(si:dkey-240h12.4) 556756(dapk2b) 558314(dapk1) 562194(dapk3) 571352(dapk2a)
IPU: 108255671(dapk1) 108267563(dapk3) 108273078 108275323(dapk2) 108280394
PHYP: 113529602(dapk2) 113537005(dapk1) 113540540(dapk3) 113543244 113543789
TRU: 101061222(dapk3) 101068981(dapk2) 101075531 101079778(dapk1)
LCO: 104926185(dapk3) 104931408(dapk2) 104932683(dapk1) 104933071 104935759
NCC: 104953446(dapk2) 104955988(dapk1) 104966057 104966802(dapk3)
ELY: 117252421(dapk1) 117252689(dapk2a) 117261858(dapk2b) 117271621(dapk3)
PLEP: 121938945 121944061(dapk1) 121950225(dapk2b) 121951609(dapk3)
SLUC: 116038391(dapk2b) 116045918(dapk3) 116054369(dapk1) 116067282(dapk2a)
GAT: 120809017(dapk2b) 120816191(dapk3) 120826486(si:dkey-240h12.4) 120830293(dapk1) 120833828
MSAM: 119884072 119889975(dapk2a) 119891316(dapk1) 119893732(dapk2b) 119901874(dapk3) 119907193(si:dkey-240h12.4)
CUD: 121509578(dapk1) 121510639(dapk2a) 121515496(dapk2b) 121520485(dapk3) 121524521(si:dkey-240h12.4)
ONL: 100694026 100696993(dapk3) 100700091(dapk1) 100701596 100702246(dapk2)
OAU: 116310816(si:dkey-240h12.4) 116313414(dapk3) 116326204(dapk2b) 116333353(dapk1) 116334300(dapk2a)
OLA: 101162667(dapk1) 101165975(dapk2) 101168492(dapk3) 101170149 101174843
OML: 112137981(si:dkey-240h12.4) 112140277(dapk2a) 112147648(dapk3) 112148257(dapk1) 112152834
XMA: 102217377(dapk1) 102223271 102232039 102234600(dapk2) 102237542(dapk3)
XCO: 114133209(dapk2) 114143674 114146973(dapk3) 114154736(dapk1) 114156085
PRET: 103460129 103466571(dapk2) 103470747(dapk1) 103471921 103479794(dapk3)
NFU: 107381541 107383256 107383608(dapk3) 107386110(dapk1) 107388750(dapk2)
KMR: 108229023(dapk2a) 108229831(dapk2b) 108232800(dapk3) 108245881(dapk1) 108248577(si:dkey-240h12.4)
CSEM: 103378952 103379969(dapk2) 103396457(dapk3) 103397800(dapk1)
SDU: 111224364 111227986(dapk1) 111228368(dapk2) 111230605 111231263(dapk3)
SLAL: 111656855 111660944(dapk1) 111667021(dapk2) 111669164(dapk3)
XGL: 120786102(si:dkey-240h12.4) 120793078(dapk2b) 120794841(dapk2a) 120799243(dapk3) 120805065(dapk1)
MALB: 109951140(dapk1) 109951241 109955329(dapk3) 109971204(dapk2) 109974564
LOC: 102683066(dapk3) 102690036 102693286(dapk2) 102696364(dapk1) 107077995
CMK: 103183535(dapk3) 103188013(dapk2) 103188174(dapk1)
RTP: 109912840(dapk3) 109927259(dapk1) 109933600
CIN: 100175927
SPU: 575268
AME: 411980
ACER: 107993455
BIM: 100743536
BTER: 100651800
CCAL: 108624768
MGEN: 117218427
SOC: 105207781
MPHA: 105834007
AEC: 105142977
ACEP: 105619276
PBAR: 105428033
VEM: 105570700
HST: 105186235
DQU: 106749593
CFO: 105248856
LHU: 105678327
PGC: 109858385
OBO: 105275689
PCF: 106786723
CSOL: 105360914
MDL: 103568431
TCA: 661340
NVL: 108558499
APLN: 108737873
PPYR: 116178870
OTU: 111413634
API: 100163654
DNX: 107162880
AGS: 114122678
RMD: 113549953
CLEC: 106667707
NLU: 111051931
ZNE: 110830966
CSEC: 111866306
PVM: 113821921
EAF: 111714130
DSV: 119446229
RSAN: 119389935
RMP: 119175350
VDE: 111246381
VJA: 111259238
TUT: 107361778
DPTE: 113789364
CEL: CELE_K12C11.4(dapk-1)
CBR: CBG08506(Cbr-dapk-1)
BMY: BM_BM5018(Bma-dapk-1)
PCAN: 112554315
PMAX: 117334782
LAK: 106158445
NVE: 5514187
EPA: 110253569
ATEN: 116288077
PDAM: 113681960
SPIS: 111325501
DGT: 114529414
HMG: 100210263
 » show all
Reference
PMID:7828849
  Authors
Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A
  Title
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.
  Journal
Genes Dev 9:15-30 (1995)
DOI:10.1101/gad.9.1.15
  Sequence
[hsa:1612]
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