KEGG   ORTHOLOGY: K08847
Entry
K08847                      KO                                     

Name
RIPK3
Definition
receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
Pathway
ko04217  Necroptosis
ko04621  NOD-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04668  TNF signaling pathway
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
   04623 Cytosolic DNA-sensing pathway
    K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine kinases: TKL group
  RIPK family [OT]
   K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3
Genes
HSA: 11035(RIPK3)
PTR: 452820(RIPK3)
PPS: 100982151(RIPK3)
GGO: 101126247(RIPK3)
PON: 100461174(RIPK3)
NLE: 100589021(RIPK3)
MCC: 716138(RIPK3)
MCF: 102124880(RIPK3)
CSAB: 103228724(RIPK3)
RRO: 104662673(RIPK3)
RBB: 108540959(RIPK3)
CJC: 100398268(RIPK3)
SBQ: 101046389(RIPK3)
MMU: 56532(Ripk3)
MCAL: 110309461(Ripk3)  
MPAH: 110325658(Ripk3)
RNO: 246240(Ripk3)
MUN: 110556511(Ripk3)
CGE: 100768712(Ripk3)
NGI: 103739494(Ripk3)
HGL: 101719112(Ripk3)
CCAN: 109685840(Ripk3)
TUP: 102503180(RIPK3)
CFA: 608486(RIPK3)
VVP: 112926559(RIPK3)  
AML: 100465668(RIPK3)
UMR: 103679293(RIPK3)
UAH: 113246058(RIPK3)
ORO: 101383873(RIPK3)
ELK: 111160345
FCA: 101097985(RIPK3)
PTG: 102965180(RIPK3)  
PPAD: 109254967(RIPK3)
AJU: 106987875(RIPK3)
BTA: 507427(RIPK3)
BOM: 102285892(RIPK3)
BIU: 109564762(RIPK3)
BBUB: 102409412(RIPK3)
CHX: 102185184(RIPK3)
OAS: 101118877(RIPK3)
SSC: 100153263(RIPK3)
CFR: 102524455(RIPK3)
CDK: 105102433(RIPK3)
BACU: 102998617(RIPK3)
LVE: 103079725(RIPK3)
OOR: 101288355(RIPK3)
PCAD: 102976899(RIPK3)
ECB: 100054255(RIPK3)
EPZ: 103561048(RIPK3)
EAI: 106848614(RIPK3)
MYB: 102247700(RIPK3)
MYD: 107182662
MNA: 107531682(RIPK3)
HAI: 109393623(RIPK3)
DRO: 112300852(RIPK3)
PALE: 102889734(RIPK3)  
RAY: 107498016(RIPK3)
MJV: 108410203(RIPK3)
LAV: 100675807(RIPK3)
TMU: 101355323
ASN: 102384398(RIPK3)
AMJ: 106737053(RIPK3)
PSS: 102451749
CMY: 102947847(RIPK3)
CPIC: 101936248(RIPK3)
ACS: 100562959(ripk3) 103282606
PVT: 110091694(RIPK3)
PBI: 103056331
PMUR: 107286631(RIPK3)
TSR: 106549301
PMUA: 114582501(RIPK3) 114582853
XLA: 108699327 108715017 733239(ripk3.S)
XTR: 100490493(ripk3.2) 100491169(ripk3.1) 100497374
DRE: 100004555(ripk3)
CCAR: 109092949
IPU: 108260981
PHYP: 113544370
AMEX: 103032582
EEE: 113581408
LCO: 104936986
XMA: 102226269
PRET: 103480422
CVG: 107091989
ALIM: 106527055
AOCE: 111585529
POV: 109624265 109646466(ripk3)
SASA: 100195444(ripk4) 106573411
SALP: 111952754
ELS: 105030095
PKI: 111856483
 » show all
Reference
  Authors
Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan FK
  Title
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.
  Journal
Cell 137:1112-23 (2009)
DOI:10.1016/j.cell.2009.05.037
Reference
  Authors
Yu PW, Huang BC, Shen M, Quast J, Chan E, Xu X, Nolan GP, Payan DG, Luo Y
  Title
Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB.
  Journal
Curr Biol 9:539-42 (1999)
DOI:10.1016/S0960-9822(99)80239-5
  Sequence
[hsa:11035]
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