KEGG   ORTHOLOGY: K09027
Entry
K09027                      KO                                     

Name
XBP1
Definition
X box-binding protein 1
Pathway
ko04141  Protein processing in endoplasmic reticulum
ko04932  Non-alcoholic fatty liver disease
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05017  Spinocerebellar ataxia
ko05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K09027  XBP1; X box-binding protein 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K09027  XBP1; X box-binding protein 1
   05012 Parkinson disease
    K09027  XBP1; X box-binding protein 1
   05014 Amyotrophic lateral sclerosis
    K09027  XBP1; X box-binding protein 1
   05017 Spinocerebellar ataxia
    K09027  XBP1; X box-binding protein 1
   05022 Pathways of neurodegeneration - multiple diseases
    K09027  XBP1; X box-binding protein 1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K09027  XBP1; X box-binding protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09027  XBP1; X box-binding protein 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    K09027  XBP1; X box-binding protein 1
Genes
HSA: 7494(XBP1)
PTR: 458735(XBP1)
PPS: 100975787(XBP1)
GGO: 101152414(XBP1)
PON: 100432230(XBP1)
NLE: 100593978(XBP1)
MCC: 713863(XBP1)
MCF: 102122252(XBP1)
CSAB: 103223125(XBP1)
RRO: 104659033(XBP1)
RBB: 108517565(XBP1)
CJC: 100406291(XBP1)
SBQ: 101051328(XBP1)
MMU: 22433(Xbp1)
MCAL: 110305540(Xbp1)
MPAH: 110330475(Xbp1)
RNO: 289754(Xbp1)
MUN: 110546119(Xbp1)
CGE: 100689062(Xbp1)
NGI: 103734968(Xbp1)
HGL: 101714834 101723083(Xbp1)
CCAN: 109690244(Xbp1)
OCU: 100339940(XBP1) 100357982
TUP: 102502358(XBP1)
CFA: 477532(XBP1)
VVP: 112906911(XBP1)
AML: 100471419(XBP1)
UMR: 103659239(XBP1)
UAH: 113245005(XBP1)
ORO: 101385284(XBP1)
ELK: 111160084
FCA: 101092150(XBP1)
PTG: 102961098(XBP1)
PPAD: 109253547(XBP1)
AJU: 106985439(XBP1)
BTA: 541236(XBP1)
BOM: 102267259(XBP1)
BIU: 109571020(XBP1)
BBUB: 102404909 102408041(XBP1)
CHX: 102184460(XBP1)
OAS: 100037692(XBP1)
SSC: 100217386(XBP1)
CFR: 102510269(XBP1)
CDK: 105099473(XBP1)
OOR: 101288279(XBP1)
DLE: 111162721(XBP1)
PCAD: 102985576(XBP1)
ECB: 100059209(XBP1)
EPZ: 103554117(XBP1)
EAI: 106827572(XBP1)
MYB: 102252117(XBP1)
MYD: 102767486(XBP1)
MNA: 107526248(XBP1)
HAI: 109383072(XBP1)
DRO: 112310648(XBP1)
PALE: 102882851(XBP1)
RAY: 107520486(XBP1)
MJV: 108408450(XBP1)
LAV: 100665921(XBP1)
TMU: 101354466
MDO: 100030619(XBP1)
SHR: 100933113(XBP1)
PCW: 110215243(XBP1)
OAA: 100077370(XBP1)
GGA: 416918(XBP1)
MGP: 100543846(XBP1)
CJO: 107321230(XBP1)
NMEL: 110406519(XBP1)
ACYG: 106043879(XBP1)
TGU: 100225681(XBP1)
LSR: 110478215(XBP1)
SCAN: 103818106(XBP1)
GFR: 102038226(XBP1)
FAB: 101810196(XBP1)
PHI: 102111268(XBP1)
PMAJ: 107211677(XBP1)
CCAE: 111936480(XBP1)
CCW: 104688792(XBP1)
ETL: 114061527(XBP1)
FPG: 101915480(XBP1)
FCH: 102047579(XBP1)
CLV: 102095307(XBP1)
EGZ: 104122586(XBP1)
NNI: 104015778(XBP1)
ACUN: 113486258(XBP1)
PADL: 103922653(XBP1)
ASN: 102380131(XBP1)
AMJ: 102575369(XBP1)
PSS: 102462347(XBP1)
CMY: 102939054
CPIC: 101954056(XBP1)
ACS: 103282887(xbp1)
PVT: 110083427(XBP1)
PBI: 103065771(XBP1)
PMUR: 107287284(XBP1)
TSR: 106548512(XBP1)
PMUA: 114586709(XBP1)
GJA: 107123922(XBP1)
XLA: 380215(xbp1.L)
XTR: 407858(xbp1)
NPR: 108800514(XBP1)
DRE: 140614(xbp1)
IPU: 108255948(xbp1)
PHYP: 113537021(xbp1)
AMEX: 103047551(xbp1)
EEE: 113583387(xbp1)
TRU: 654272(xbp1)
LCO: 104920672(xbp1)
NCC: 104960857(xbp1)
MZE: 101480626(xbp1)
ONL: 100695162(xbp1)
OLA: 101157780(xbp1)
XMA: 102236159(xbp1)
XCO: 114154693(xbp1)
PRET: 103469857(xbp1)
CVG: 107091970(xbp1)
NFU: 107386234(xbp1)
KMR: 108242736(xbp1)
ALIM: 106536617(xbp1)
AOCE: 111581888(xbp1)
CSEM: 103397862
LCF: 108901516(xbp1)
SDU: 111227347(xbp1)
SLAL: 111663093(xbp1)
HCQ: 109513466(xbp1)
BPEC: 110172081(xbp1)
MALB: 109973998(xbp1)
SASA: 100846957(xbp1)
ELS: 105014054(xbp1)
SFM: 108925673
PKI: 111849892
LCM: 102351750(XBP1)
CMK: 103182222(xbp1)
RTP: 109922126(xbp1)
BFO: 118425763
CIN: 778793(xbpa)
SPU: 586069
APLC: 110980723
SKO: 100313767
DME: Dmel_CG9415(Xbp1)
DER: 6547724
DSE: 6615310
DSI: Dsimw501_GD11567(Dsim_GD11567)
DSR: 110179233
DPE: 6600824
DMN: 108160522
DWI: 6639831
DAZ: 108616483
DNV: 108655016
DHE: 111597050
DVI: 6626562
MDE: 101892805
LCQ: 111680384
AAG: 5566687
AALB: 109407580
AME: 408853
BIM: 100747421
BTER: 100647771
CCAL: 108624678
OBB: 114872906
SOC: 105204009
MPHA: 105835938
AEC: 105147747
ACEP: 105620358
PBAR: 105431521
VEM: 105565821
HST: 109504605
DQU: 106746034
CFO: 105254579
LHU: 105677165
PGC: 109861796
OBO: 105278889
PCF: 106789741
NVI: 116417701
CSOL: 105360481
MDL: 103575939
TCA: 662495
DPA: 109539322
NVL: 108559806
BMOR: 101742474
BMAN: 114246266
PMAC: 106718520
PRAP: 110996634
HAW: 110372696
TNL: 113506682
PXY: 105394282
API: 100574802
DNX: 107170585
AGS: 114126958
RMD: 113560315
CLEC: 106663737
ZNE: 110833290
FCD: 110856891
TUT: 107364867
CSCU: 111612829
PTEP: 107444128
CEL: CELE_R74.3(xbp-1)
CBR: CBG20165(Cbr-xbp-1)
BMY: Bm1_47240
PCAN: 112561243
MYI: 110460731
OBI: 106880675
SHX: MS3_06947
EGL: EGR_01473
NVE: 5509200
EPA: 110253316
ADF: 107342737
AMIL: 114968976
PDAM: 113679381
SPIS: 111333026
DGT: 114520595
HMG: 100198653
AQU: 100636782
 » show all
Reference
  Authors
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K
  Title
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
  Journal
Cell 107:881-91 (2001)
DOI:10.1016/S0092-8674(01)00611-0
  Sequence
[hsa:7494]
Reference
PMID:2321018
  Authors
Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH
  Title
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter.
  Journal
Science 247:1581-4 (1990)
DOI:10.1126/science.2321018
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