KEGG   ORTHOLOGY: K09105
Entry
K09105                      KO                                     

Name
TFE3
Definition
transcription factor E3
Pathway
ko04137  Mitophagy - animal
ko05202  Transcriptional misregulation in cancer
ko05211  Renal cell carcinoma
Disease
H00021  Renal cell carcinoma
H00051  Alveolar soft part sarcoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K09105  TFE3; transcription factor E3
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K09105  TFE3; transcription factor E3
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K09105  TFE3; transcription factor E3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09105  TFE3; transcription factor E3
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Ubiquitous bHLH-ZIP factors
    K09105  TFE3; transcription factor E3
Genes
HSA: 7030(TFE3)
PTR: 473871(TFE3)
PPS: 100984828(TFE3)
GGO: 101125478(TFE3)
PON: 100456828(TFE3)
NLE: 100604394(TFE3)
MCC: 712161(TFE3)
MCF: 102144652(TFE3)
CSAB: 103231961(TFE3)
RRO: 104661804(TFE3)
RBB: 108539574(TFE3)
CJC: 100415467(TFE3)
SBQ: 101030478(TFE3)
MMU: 209446(Tfe3)
MCAL: 110286603(Tfe3)  
MPAH: 110313440(Tfe3)
RNO: 317376(Tfe3)
MUN: 110561989(Tfe3)
CGE: 100761176(Tfe3)
NGI: 103741661(Tfe3)
HGL: 101715111(Tfe3)
CCAN: 109699888(Tfe3)
OCU: 100346824(TFE3)
TUP: 102492524(TFE3)
CFA: 491872(TFE3)
VVP: 112907233(TFE3)  
AML: 100470680(TFE3)
UMR: 103668211(TFE3)
UAH: 113265941(TFE3)
ORO: 101384968(TFE3)
ELK: 111150460
FCA: 101099025(TFE3)
PTG: 102970329(TFE3)  
PPAD: 109248086(TFE3)
AJU: 106989005(TFE3)
BTA: 520800(TFE3)
BOM: 102266511(TFE3)
BIU: 109555311(TFE3)
BBUB: 102404675(TFE3)
CHX: 102169369(TFE3)
OAS: 101106403(TFE3)
SSC: 100511298(TFE3)
CFR: 102508358(TFE3)
CDK: 105103295(TFE3)
BACU: 103009619(TFE3)
LVE: 103078248(TFE3)
OOR: 101285380(TFE3)
DLE: 111169489(TFE3)
PCAD: 102996231(TFE3)
ECB: 100051983(TFE3)
EPZ: 103544261(TFE3)
EAI: 106826972(TFE3)
MYB: 102257388(TFE3)
MYD: 102767749(TFE3)
MNA: 107541383(TFE3)
HAI: 109374805(TFE3)
DRO: 112322459(TFE3)
PALE: 102885286(TFE3)  
RAY: 107515012(TFE3)
MJV: 108396229(TFE3)
LAV: 100676073(TFE3)
TMU: 101344296
MDO: 100019256(TFE3)
SHR: 100919901(TFE3)
PCW: 110201082(TFE3)
OAA: 100076328(TFE3)
GGA: 107049522(TFE3)
PHI: 102102349(TFE3)
ASN: 102373591
AMJ: 109283989(TFE3)
PSS: 102460698
CMY: 102943023
CPIC: 101951556(TFE3)
ACS: 100551955(tfe3)
PVT: 110081166(TFE3)
PBI: 103068156(TFE3)
PMUR: 107292057(TFE3)
PMUA: 114587522(TFE3)
XLA: 108698087(tfe3.L) 495043(tfe3.S)
XTR: 100490005(tfe3)
NPR: 108789238(TFE3)
DRE: 114834(tfe3a) 564996(tfe3b)
IPU: 108265526
PHYP: 113535077(tfe3)
EEE: 113575840 113586556(tfe3)
NCC: 104945760(tfe3)
OLA: 101166296(tfe3) 101174799
XMA: 102225584(tfe3) 102231855
XCO: 114135530(tfe3) 114140718
PRET: 103465541(tfe3)
CVG: 107099672(tfe3) 107100387
KMR: 108228826 108244409(tfe3)
ALIM: 106531385(tfe3) 106533782
AOCE: 111573973(tfe3) 111585597
CSEM: 103384379(tfe3) 103386412
SLAL: 111649271(tfe3) 111654971
HCQ: 109521480 109521547(tfe3)
PKI: 111856146 111857008(tfe3)
LCM: 102365950(TFE3)
CIN: 778681(mitf)
SPU: 577766
TNL: 113495892
PXY: 105388676
CSCU: 111623771
CBR: CBG24924
TSP: Tsp_10832
 » show all
Reference
  Authors
Skalsky YM, Ajuh PM, Parker C, Lamond AI, Goodwin G, Cooper CS
  Title
PRCC, the commonest TFE3 fusion partner in papillary renal carcinoma is associated with pre-mRNA splicing factors.
  Journal
Oncogene 20:178-87 (2001)
DOI:10.1038/sj.onc.1204056
Reference
PMID:2338243
  Authors
Beckmann H, Su LK, Kadesch T
  Title
TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.
  Journal
Genes Dev 4:167-79 (1990)
DOI:10.1101/gad.4.2.167
  Sequence
[hsa:7030]
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