KEGG   ORTHOLOGY: K09680
Entry
K09680                      KO                                     

Name
PANK1_2_3, CAB1, coaW
Definition
type II pantothenate kinase [EC:2.7.1.33]
Pathway
ko00770  Pantothenate and CoA biosynthesis
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00120  Coenzyme A biosynthesis, pantothenate => CoA
Disease
H00832  Core neuroacanthocytosis syndromes
H00833  Neurodegeneration with brain iron accumulation
H02208  Pantothenate kinase-associated neurodegeneration
H02209  HARP syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    K09680  PANK1_2_3, CAB1, coaW; type II pantothenate kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.33  pantothenate kinase
     K09680  PANK1_2_3, CAB1, coaW; type II pantothenate kinase
Other DBs
RN: R02971 R03018 R04391
COG: COG5146
GO: 0004594
Genes
HSA: 53354(PANK1) 79646(PANK3) 80025(PANK2)
PTR: 450590(PANK1) 458070(PANK2) 462250(PANK3)
PPS: 100971193(PANK3) 100978738(PANK1) 100981323(PANK2)
GGO: 101125460(PANK2) 101129291(PANK3) 101130682(PANK1)
PON: 100171452(PANK1) 100432599(PANK2) 100451199(PANK3)
NLE: 100584898(PANK2) 100586759(PANK1) 100594258(PANK3)
MCC: 100427204(PANK3) 696041(PANK1) 717639(PANK2)
MCF: 102115196(PANK1) 102123167(PANK3)
CSAB: 103216236(PANK1) 103244943(PANK3) 103247622(PANK2)
RRO: 104658232(PANK3) 104674591(PANK2) 104675800(PANK1)
RBB: 108513600(PANK3) 108533464(PANK2) 108544923(PANK1)
CJC: 100396390(PANK2) 100407841(PANK1) 100414828(PANK3)
SBQ: 101031203(PANK1) 101049443 101053770(PANK3)
MMU: 211347(Pank3) 74450(Pank2) 75735(Pank1)
MCAL: 110286043(Pank1) 110290470(Pank2) 110304878(Pank3)
MPAH: 110318536(Pank2) 110320914(Pank1) 110331557(Pank3)
RNO: 294088(Pank1) 296167(Pank2) 360511(Pank3)
MUN: 110545406(Pank3) 110553483(Pank1) 110559620(Pank2)
CGE: 100767141(Pank3) 100768798(Pank1) 100773397(Pank2)
NGI: 103731738(Pank3) 103736401(Pank2) 103747251(Pank1)
HGL: 101707167(Pank2) 101710621(Pank3) 101717132(Pank1)
CCAN: 109678203(Pank1) 109686852(Pank3) 109691284(Pank2)
OCU: 100339088(PANK1) 100356784(PANK3) 100357050(PANK2)
TUP: 102468852(PANK3) 102475880(PANK2) 102481097(PANK1)
CFA: 111092250 477168(PANK2) 486790(PANK1) 489133(PANK3)
VVP: 112913646(PANK1) 112926403(PANK3) 112930077(PANK2)
AML: 100465827(PANK1) 100467070(PANK2) 100479827(PANK3)
UMR: 103664508(PANK3) 103667942(PANK1) 103674400(PANK2)
UAH: 113243152(PANK1) 113258385(PANK2) 113264071(PANK3)
ORO: 101366990(PANK1) 101368032(PANK2) 101384743(PANK3)
FCA: 101085099(PANK3) 101092510 101101593(PANK1)
PTG: 102952852(PANK2) 102968260(PANK1) 102970972(PANK3)
PPAD: 109264630(PANK1) 109267464(PANK3) 109274755(PANK2)
AJU: 106969259(PANK3) 106972134(PANK1) 106980149(PANK2)
BTA: 510749(PANK3) 535887(PANK1) 535933(PANK2)
BOM: 102270683(PANK1) 102275833(PANK3) 102282630(PANK2)
BIU: 109553047(PANK1) 109567184(PANK2) 109574885(PANK3)
BBUB: 102411140(PANK2) 102413378(PANK1) 102414318(PANK3)
CHX: 102170661(PANK1) 102177992(PANK2) 102182632(PANK3)
OAS: 100217410(PANK2) 101103923(PANK3) 101122150(PANK1)
SSC: 100154650(PANK1) 100512746(PANK3) 100520054(PANK2)
CFR: 102513935(PANK1) 102520847(PANK2)
CDK: 105089392(PANK3) 105096052(PANK2) 105102839(PANK1)
BACU: 103012494 103013310(PANK3) 103014459(PANK2) 103017263(PANK1)
LVE: 103077405(PANK3) 103078754(PANK2) 103080137(PANK1)
OOR: 101272097(PANK3) 101272287(PANK1) 101284302(PANK2)
DLE: 111172507(PANK1) 111184406(PANK2) 111185493(PANK3)
PCAD: 102977352 102994406(PANK1) 102995917(PANK3)
ECB: 100059344(PANK3) 100066127(PANK2) 100071561(PANK1)
EPZ: 103543108(PANK3) 103559806(PANK2) 103560243(PANK1)
EAI: 106830026(PANK1) 106837375(PANK3) 106847675(PANK2)
MYB: 102244250(PANK2) 102256406(PANK4) 102261506(PANK1) 102264041(PANK3)
MYD: 102757477(PANK3) 102762304(PANK1) 102768315(PANK2) 102773077(PANK4)
MNA: 107536393(PANK2) 107537879(PANK3) 107543329(PANK1)
HAI: 109376124(PANK1) 109379404(PANK3) 109383810(PANK2)
DRO: 112303907(PANK2) 112307338(PANK1) 112319598(PANK3)
PALE: 102877801(PANK1) 102889543(PANK3) 112470959
RAY: 107501618(PANK1) 107506020(PANK2) 107514070(PANK3)
LAV: 100655128(PANK3) 100658201(PANK1) 100663806(PANK2)
MDO: 100024817(PANK1) 100026148(PANK3) 100031061(PANK2)
SHR: 100920860(PANK3) 100925122(PANK1) 100926532(PANK2)
PCW: 110192748(PANK1) 110212324(PANK3) 110218366(PANK2)
OAA: 100075242(PANK1) 100078163(PANK3) 100082783(PANK2)
GGA: 416170(PANK3) 422935(PANK2) 423792(PANK1)
MGP: 100538379(PANK1) 100539295 100540294(PANK3)
CJO: 107314114 107315880(PANK1) 107320250(PANK3)
NMEL: 110397562(PANK2) 110399629(PANK1) 110405372(PANK3)
APLA: 101794180(PANK2) 101795622(PANK1) 101801530(PANK3)
ACYG: 106034374(PANK3) 106036778(PANK2) 106043769(PANK1)
TGU: 100220803(PANK1) 100226291(PANK2) 100226807(PANK3)
LSR: 110469664(PANK3) 110473319(PANK2) 110475338(PANK1)
SCAN: 103813928(PANK1) 103817229(PANK3) 103823124(PANK2)
GFR: 102032868(PANK1) 102038183(PANK2) 102045314(PANK3)
FAB: 101807025(PANK1) 101813495(PANK3) 101817723(PANK2)
PHI: 102103182(PANK1) 102104749(PANK2) 102109296(PANK3)
PMAJ: 107203524(PANK2) 107206808(PANK1) 107210788(PANK3)
CCAE: 111929112(PANK2) 111931172(PANK1) 111935737(PANK3)
CCW: 104690828(PANK2) 104693533(PANK3) 104696382(PANK1)
FPG: 101915750(PANK1) 101916298(PANK3)
FCH: 102055505(PANK3) 102059836(PANK1) 114014850(PANK2)
CLV: 102085385(PANK1) 102087942(PANK3) 102088811(PANK2)
EGZ: 104125970 104128756(PANK3) 104129159(PANK1)
NNI: 104013081(PANK1) 104016549(PANK3) 104018558(PANK2)
ACUN: 113479083(PANK2) 113481389(PANK1) 113485192(PANK3)
PADL: 103912268(PANK3) 103913623(PANK1) 103923497(PANK2)
AAM: 106484544 106487844(PANK1) 106493595(PANK3)
ASN: 102375189 102383150(PANK2) 102386228(PANK3)
AMJ: 102560784(PANK3) 102563201(PANK1) 106737235(PANK2)
PSS: 102455137(PANK1) 102455291(PANK3) 102459697(PANK2)
CMY: 102936382(PANK2) 102938589(PANK1)
CPIC: 101935653(PANK3) 101940196(PANK1) 101940631(PANK2)
ACS: 100564310(pank3) 100566757(pank1) 103282996(pank4)
PVT: 110084124(PANK1) 110085980 110088051(PANK3)
PBI: 103055938 103057938(PANK2) 103061454(PANK1)
TSR: 106544375(PANK3) 106547806 106549109(PANK4)
PMUA: 114592114 114597306(PANK1) 114604223(PANK2)
XTR: 100135204(pank3) 100485781(pank1) 100487302(pank2)
NPR: 108791904(PANK3) 108792151(PANK1) 108801916
DRE: 406789(pank1a) 565059(pank1b) 570866(pank2)
IPU: 108263243(pank2) 108269561 108274120(pank1)
PHYP: 113527508(pank1) 113545669(pank2) 113547713
AMEX: 103044193(pank2) 103047703(pank1)
TRU: 115249552(pank1)
PRET: 103458183(pank2) 103476444
ALIM: 106515389 106524280(pank2)
POV: 109634111(pank1) 109636488
LCM: 102345468(PANK3) 102345555(PANK2) 102360532(PANK1)
CMK: 103180761(pank1) 103181500(pank2) 103186478(pank3)
BFO: 118414442
CIN: 100183199
SPU: 590061
APLC: 110977050
SKO: 100369486
DME: Dmel_CG5725(fbl) Dmel_CG5828(CG5828)
DSI: Dsimw501_GD14883(Dsim_GD14883) Dsimw501_GD23321(Dsim_GD23321)
AME: 726156
BIM: 100745218
BTER: 100642303
CCAL: 108630633
OBB: 114874444
SOC: 105199314
MPHA: 105835370
AEC: 105148170
ACEP: 105624789
PBAR: 105431937
VEM: 105564087
HST: 105188945
DQU: 106741822
CFO: 105255118
LHU: 105672544
PGC: 109852323
OBO: 105286360
PCF: 106790043
NVI: 100120948
CSOL: 105364197
MDL: 103570950
TCA: 658254(fbl) 658499
API: 100160427
AGS: 114124074
RMD: 113551899
BTAB: 109036859
ZNE: 110837778
FCD: 110852990
PVM: 113819409
TUT: 107369176
DPTE: 113788414
CEL: CELE_C42D8.3(pnk-4)
CBR: CBG14606(Cbr-uvt-3)
BMY: Bm1_40300
TSP: Tsp_01576
PCAN: 112565320
CRG: 105318949
MYI: 110457163
OBI: 106868598
LAK: 106176544
EGL: EGR_08535
ADF: 107350274
AMIL: 114962797
PDAM: 113665808
SPIS: 111324452
DGT: 114538041
AQU: 100641329
ATH: AT1G60440(PANK1) AT4G32180(PANK2)
LJA: Lj0g3v0033919.1(Lj0g3v0033919.1) Lj0g3v0135599.1(Lj0g3v0135599.1) Lj0g3v0326819.1(Lj0g3v0326819.1) Lj1g3v0409010.1(Lj1g3v0409010.1)
PXB: 103953015
NNU: 104587232
DOSA: Os06t0207000-01(Os06g0207000) Os09t0533100-01(Os09g0533100)
ATS: 109735683(LOC109735683) 109760200(LOC109760200)
ZMA: 100280926(cl35695_1) 103633092
APRO: F751_6444
MIS: MICPUN_113383(PANK)
SCE: YDR531W(CAB1)
ERC: Ecym_1024
KMX: KLMA_10036(CAB1)
NCS: NCAS_0A00220(NCAS0A00220)
NDI: NDAI_0F04600(NDAI0F04600)
TPF: TPHA_0E03890(TPHA0E03890)
TBL: TBLA_0A07420(TBLA0A07420)
TDL: TDEL_0C06850(TDEL0C06850)
KAF: KAFR_0H03730(KAFR0H03730)
CAL: CAALFM_C602980CA(CaO19.5577)
SLB: AWJ20_1863(CAB1)
NCR: NCU03154
NTE: NEUTE1DRAFT72518(NEUTE1DRAFT_72518)
MGR: MGG_17976
SSCK: SPSK_06125
MAW: MAC_00893
MAJ: MAA_03865
CMT: CCM_03267
BFU: BCIN_06g01960(Bccab1)
MBE: MBM_00678
ANI: AN9446.2
ANG: ANI_1_3272024(An02g13550)
ABE: ARB_07375
TVE: TRV_00225
PTE: PTT_15290
CNE: CNC04810
CNB: CNBC2370
TASA: A1Q1_01029
ABP: AGABI1DRAFT67158(AGABI1DRAFT_67158)
ABV: AGABI2DRAFT197040(AGABI2DRAFT_197040)
MGL: MGL_2307
MRT: MRET_0205
DFA: DFA_11497
PCB: PCHAS_102340(PC300595.00.0)
TPV: TP04_0450
BBO: BBOV_II001350(18.m06102)
SMIN: v1.2.021962.t2(symbB.v1.2.021962.t2) v1.2.021962.t3(symbB.v1.2.021962.t3) v1.2.037190.t1(symbB.v1.2.037190.t1)
BAN: BA_2901(coaA)
BAR: GBAA_2901(coaA)
BAT: BAS2702
BAH: BAMEG_1699(coaA)
BAI: BAA_2957(coaA)
BANT: A16_29300
BANR: A16R_29740
BANS: BAPAT_2785
BANV: DJ46_1669(coaA)
BCE: BC2898
BCA: BCE_2940
BCR: BCAH187_A2950(coaA)
BCB: BCB4264_A2918(coaA)
BCU: BCAH820_2903(coaA)
BCG: BCG9842_B2329(coaA)
BCQ: BCQ_2736
BCX: BCA_2979(coaA)
BNC: BCN_2760
BCF: bcf_14180
BCER: BCK_20375
BTL: BALH_2604
BTB: BMB171_C2604(coaA)
BTT: HD73_3076
BTHI: BTK_15255
BTC: CT43_CH2894(coaA)
BTM: MC28_2089(coaW)
BTG: BTB_c30190(coaW)
BTI: BTG_04850
BTW: BF38_4061(coaA)
BWW: bwei_2124(coaW)
BMYO: BG05_3120(coaA)
BMYC: DJ92_5369(coaA)
BTRO: FJR70_04635(coaW)
OIH: OB2682
LSP: Bsph_2165
LPAK: GDS87_08915(coaW)
AQT: FN924_06535(coaW)
PSYO: PB01_08385
SAU: SA1932
SAV: SAV2130
SAW: SAHV_2114
SAM: MW2054
SAS: SAS2033
SAR: SAR2218
SAC: SACOL2122
SAX: USA300HOU_2119(coaA)
SAA: SAUSA300_2084(coaA)
SAE: NWMN_2034
SAD: SAAV_2185
SUU: M013TW_2089(coaW)
SUE: SAOV_2171
SUJ: SAA6159_02044(panK)
SUK: SAA6008_02168(panK)
SUC: ECTR2_1986(coaA)
SUQ: HMPREF0772_11060(coaA)
SUZ: MS7_2148(coaA)
SUW: SATW20_22680(coaW)
SUG: SAPIG2172(coaA)
SUF: SARLGA251_19310(coaW)
SAUA: SAAG_02344
SAUE: RSAU_001968(coaW)
SAUS: SA40_1889(coaW)
SAUU: SA957_1973(coaW)
SAUG: SA268_2043(coaW)
SAUZ: SAZ172_2234(coaW)
SAUT: SAI1T1_2015700(coaW)
SAUJ: SAI2T2_1015710(coaW)
SAUK: SAI3T3_1015700(coaW)
SAUQ: SAI4T8_1015710(coaW)
SAUV: SAI7S6_1015710(coaW)
SAUW: SAI5S5_1015650(coaW)
SAUX: SAI6T6_1015660(coaW)
SAUY: SAI8T7_1015690(coaW)
SAUF: X998_2109
SAB: SAB2014
SAUB: C248_2145
SAUC: CA347_2210(coaA)
SAUR: SABB_02455(coaW)
SAUI: AZ30_11245
SAUD: CH52_08310
SAMS: NI36_10460
SER: SERP1737
SEP: SE1728
SEPP: SEB_01739
SEPS: DP17_673(coaA)
SHA: SH0905
SHH: ShL2_00796(panK)
SSP: SSP0755
SCA: SCA_1634
SDT: SPSE_0689(coaA)
SPAS: STP1_0564
SXO: SXYL_00803(coaW)
SHU: SHYC_03620(coaA)
SCAP: AYP1020_1317(coaW)
SSCH: LH95_03450
SSCZ: RN70_03720
SAGQ: EP23_06450(coaW)
SHOM: EGX58_07975(coaW)
SFF: FOB90_04315(coaW)
SDP: NCTC12225_00760(coaA)
SARL: SAP2_08200(coaW)
MCL: MCCL_1785
MCAK: MCCS_23000(coaW)
PPSC: EHS13_31555(coaW)
PBK: Back11_15240(coaW)
SIV: SSIL_2612
KUR: ASO14_1906(coaA)
KZO: NCTC404_01804(coaW)
PANC: E2636_08665(coaW)
PGQ: FK545_08755(coaW)
PLAY: DNR44_002015(coaW)
VIJ: JNUCC6_21690(coaW)
ASF: SFBM_0407
CCE: Ccel_0705
CSD: Clst_1114
CCT: CC1_01470
OVA: OBV_27770
MRB: Mrub_1085
GAU: GAU_3146
BCEL: BcellWH2_04433(coaW)
BIS: DXK01_011405(coaW)
BVU: BVU_3836
PDI: BDI_2301
PRU: PRU_0313
POC: NCTC13071_01854(coaW)
BACC: BRDCF_p1896(coaW)
KCR: Kcr_1599
 » show all
Reference
  Authors
Tilton GB, Wedemeyer WJ, Browse J, Ohlrogge J
  Title
Plant coenzyme A biosynthesis: characterization of two pantothenate kinases from Arabidopsis.
  Journal
Plant Mol Biol 61:629-42 (2006)
DOI:10.1007/s11103-006-0037-4
  Sequence
Reference
  Authors
Olzhausen J, Schubbe S, Schuller HJ
  Title
Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1.
  Journal
Curr Genet 55:163-73 (2009)
DOI:10.1007/s00294-009-0234-1
  Sequence
[sce:YDR531W]
Reference
  Authors
Hortnagel K, Prokisch H, Meitinger T
  Title
An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria.
  Journal
Hum Mol Genet 12:321-7 (2003)
DOI:10.1093/hmg/ddg026
  Sequence
[hsa:80025]
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