KEGG   ORTHOLOGY: K10030
Entry
K10030                      KO                                     

Name
IL8, CXCL8
Definition
interleukin 8
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04062  Chemokine signaling pathway
map04064  NF-kappa B signaling pathway
map04072  Phospholipase D signaling pathway
map04218  Cellular senescence
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04657  IL-17 signaling pathway
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05133  Pertussis
map05134  Legionellosis
map05135  Yersinia infection
map05142  Chagas disease
map05144  Malaria
map05146  Amoebiasis
map05161  Hepatitis B
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05167  Kaposi sarcoma-associated herpesvirus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
map05219  Bladder cancer
map05323  Rheumatoid arthritis
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04072 Phospholipase D signaling pathway
    K10030  IL8, CXCL8; interleukin 8
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K10030  IL8, CXCL8; interleukin 8
   04061 Viral protein interaction with cytokine and cytokine receptor
    K10030  IL8, CXCL8; interleukin 8
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    K10030  IL8, CXCL8; interleukin 8
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04621 NOD-like receptor signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04622 RIG-I-like receptor signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04657 IL-17 signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04062 Chemokine signaling pathway
    K10030  IL8, CXCL8; interleukin 8
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K10030  IL8, CXCL8; interleukin 8
   05202 Transcriptional misregulation in cancer
    K10030  IL8, CXCL8; interleukin 8
  09162 Cancer: specific types
   05219 Bladder cancer
    K10030  IL8, CXCL8; interleukin 8
  09172 Infectious disease: viral
   05161 Hepatitis B
    K10030  IL8, CXCL8; interleukin 8
   05171 Coronavirus disease - COVID-19
    K10030  IL8, CXCL8; interleukin 8
   05164 Influenza A
    K10030  IL8, CXCL8; interleukin 8
   05163 Human cytomegalovirus infection
    K10030  IL8, CXCL8; interleukin 8
   05167 Kaposi sarcoma-associated herpesvirus infection
    K10030  IL8, CXCL8; interleukin 8
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K10030  IL8, CXCL8; interleukin 8
   05130 Pathogenic Escherichia coli infection
    K10030  IL8, CXCL8; interleukin 8
   05132 Salmonella infection
    K10030  IL8, CXCL8; interleukin 8
   05131 Shigellosis
    K10030  IL8, CXCL8; interleukin 8
   05135 Yersinia infection
    K10030  IL8, CXCL8; interleukin 8
   05133 Pertussis
    K10030  IL8, CXCL8; interleukin 8
   05134 Legionellosis
    K10030  IL8, CXCL8; interleukin 8
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K10030  IL8, CXCL8; interleukin 8
   05144 Malaria
    K10030  IL8, CXCL8; interleukin 8
   05142 Chagas disease
    K10030  IL8, CXCL8; interleukin 8
  09163 Immune disease
   05323 Rheumatoid arthritis
    K10030  IL8, CXCL8; interleukin 8
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K10030  IL8, CXCL8; interleukin 8
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K10030  IL8, CXCL8; interleukin 8
   04933 AGE-RAGE signaling pathway in diabetic complications
    K10030  IL8, CXCL8; interleukin 8
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K10030  IL8, CXCL8; interleukin 8
   00536 Glycosaminoglycan binding proteins
    K10030  IL8, CXCL8; interleukin 8
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Chemokines
   K10030  IL8, CXCL8; interleukin 8
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Chemokines
   K10030  IL8, CXCL8; interleukin 8
Other DBs
GO: 0005153
Genes
HSA: 3576(CXCL8)
PTR: 471205(CXCL8)
PPS: 100978369(CXCL8)
GGO: 101130732(CXCL8)
PON: 100437111 100437488 112128505
NLE: 100586157(CXCL8)
MCC: 613028(CXCL8)
MCF: 102127272(CXCL8)
CSAB: 103235786(CXCL8)
CATY: 105596231(CXCL8)
PANU: 100381196(CXCL8)
RRO: 104658873(CXCL8)
RBB: 108523449(CXCL8)
TFN: 117085498(CXCL8)
PTEH: 111531283(CXCL8)
CJC: 100390587(CXCL8)
SBQ: 101049298(CXCL8)
MMUR: 105860250(CXCL8)
MCOC: 116104586
NGI: 103742429(Cxcl8)
HGL: 101707734(Cxcl8)
CCAN: 109691927(Cxcl8)
OCU: 100009129(CXCL8)
TUP: 102471344(CXCL8)
CFA: 403850(CXCL8)
VVP: 112909246(CXCL8)
VLG: 121473554(CXCL8)
AML: 100472054(CXCL8)
UMR: 103665307(CXCL8)
UAH: 113263279(CXCL8)
ORO: 101365039(CXCL8)
ELK: 111149115
MPUF: 101676365(CXCL8)
EJU: 114206856(CXCL8)
MLX: 118010458(CXCL8)
FCA: 493836(CXCL8)
PTG: 102953024(IL8) 102953898
PPAD: 109277765
AJU: 106981787 106982166(CXCL8)
HHV: 120231052(CXCL8)
BTA: 100847175 280828(CXCL8)
BOM: 102268124(CXCL8)
BIU: 109560570(CXCL8) 109560575
BBUB: 102412933(CXCL8)
CHX: 102178438(CXCL8)
OAS: 443418(CXCL8)
ODA: 120861430(CXCL8)
SSC: 396880(CXCL8)
CFR: 102506409(CXCL8)
CDK: 105091344(CXCL8)
BACU: 103006782(CXCL8)
LVE: 103086219(CXCL8)
OOR: 101278129(CXCL8)
DLE: 111187634(CXCL8)
PCAD: 102979960(CXCL8)
ECB: 100037400(CXCL8)
EPZ: 103566768(CXCL8)
EAI: 106835113(CXCL8)
MYB: 102243203(CXCL8)
MYD: 102761051(CXCL8)
MMYO: 118670543(CXCL8) 118671044
MNA: 107534494(CXCL8)
HAI: 109394819(CXCL8)
DRO: 112321932(CXCL8)
SHON: 118999083 118999088(CXCL8)
AJM: 119052814(CXCL8) 119052819
PALE: 102892534(CXCL8)
RAY: 107515317 107515319(CXCL8)
MJV: 108398727 108406440(CXCL8)
TOD: 119261091(CXCL8)
LAV: 100664099(CXCL8)
TMU: 101358515
MDO: 100023722(IL8)
SHR: 100933600(CXCL8)
PCW: 110209794
OAA: 103170567
GGA: 395872(IL8L1) 396495(IL8L2)
MGP: 100034742(IL8) 100546187
CLV: 102090447(IL-8) 102094827
AMJ: 102567477(CXCL8) 102567713 102568190(IL8L1) 102574675(IL8)
GGN: 109297134
CPIC: 101952445(CXCL8)
ACS: 100563503
PMUR: 107282386
PGUT: 117665048
PMUA: 114582309
ZVI: 118094983
GJA: 107114920
XLA: 100036815(cxcl8.L) 100037000(XB5945946.L) 108706143 108706149 108706768(cxcl2.S) 108706769(cxcl8.S) 108711085(cxcl2.L) 108711090 108711093
DRE: 100002946(cxcl8a) 100003859(cxcl8b.3) 100003911(cxcl19)
TRU: 105418180 445923(il8)
ELY: 117246314(cxcl19) 117255694
GAT: 120813977(cxcl8a) 120821273(cxcl19) 120821274
OML: 112141025 112156130(cxcl19) 112156986(cxcl8a)
CTUL: 119773415(cxcl19) 119794214
 » show all
Reference
PMID:1639201
  Authors
Baggiolini M, Clark-Lewis I
  Title
Interleukin-8, a chemotactic and inflammatory cytokine.
  Journal
FEBS Lett 307:97-101 (1992)
DOI:10.1016/0014-5793(92)80909-Z
  Sequence
[hsa:3576]
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