KEGG   ORTHOLOGY: K10158
Entry
K10158                      KO                                     

Name
B3GAT3
Definition
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135]
Pathway
ko00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
ko00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
ko01100  Metabolic pathways
Module
M00057  Glycosaminoglycan biosynthesis, linkage tetrasaccharide
Disease
H01498  Multiple joint dislocations, short stature, craniofacial dysmorphism, and congenital heart defects
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.135  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
     K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Other DBs
RN: R05928
GO: 0015018
CAZy: GT43
Genes
HSA: 26229(B3GAT3)
PTR: 740388(B3GAT3)
PPS: 103783318(B3GAT3)
GGO: 109028750(B3GAT3)
PON: 100458701(B3GAT3)
NLE: 100592146(B3GAT3)
MCC: 718744(B3GAT3)
MCF: 101867087(B3GAT3)
CSAB: 103234006(B3GAT3)
RRO: 104679349(B3GAT3)
RBB: 108533582(B3GAT3)
CJC: 100395367(B3GAT3)
SBQ: 101034661(B3GAT3)
MMU: 72727(B3gat3)
MCAL: 110285876(B3gat3)
MPAH: 110320357(B3gat3)
RNO: 293722(B3gat3)
MUN: 110557462(B3gat3)
CGE: 100689419(B3gat3)
NGI: 103737681(B3gat3)
HGL: 101717898(B3gat3)
CCAN: 109681240(B3gat3)
OCU: 100350294(B3GAT3)
TUP: 102472891(B3GAT3)
CFA: 483785(B3GAT3)
VVP: 112924375(B3GAT3)
AML: 100467358(B3GAT3)
UMR: 103678187(B3GAT3)
UAH: 113247005(B3GAT3)
ORO: 101373124(B3GAT3)
ELK: 111150202
FCA: 101089044(B3GAT3)
PTG: 102948861(B3GAT3)
PPAD: 109246589(B3GAT3)
AJU: 106981737(B3GAT3)
BTA: 404162(B3GAT3)
BOM: 102269297(B3GAT3)
BIU: 109554349(B3GAT3)
BBUB: 102399906(B3GAT3)
CHX: 102172516(B3GAT3)
OAS: 101111917(B3GAT3)
SSC: 397642(B3GAT3)
CFR: 102505525(B3GAT3)
CDK: 105091529(B3GAT3)
BACU: 103002629(B3GAT3)
LVE: 103078862(B3GAT3)
OOR: 101279944(B3GAT3)
DLE: 111183870(B3GAT3)
PCAD: 102996092(B3GAT3)
ECB: 100063587(B3GAT3)
EPZ: 103558932(B3GAT3)
EAI: 106826833(B3GAT3)
MYD: 102752313(B3GAT3)
MNA: 107543104(B3GAT3)
HAI: 109384098(B3GAT3)
DRO: 112317373(B3GAT3)
PALE: 102891455(B3GAT3)
RAY: 107501598(B3GAT3)
MJV: 108393625(B3GAT3)
LAV: 100672369(B3GAT3)
TMU: 101344059
MDO: 100010236(B3GAT3)
SHR: 100935255(B3GAT3)
PCW: 110195593(B3GAT3)
OAA: 100075413(B3GAT3)
PHI: 102105592(B3GAT3)
ASN: 102375316(B3GAT3)
AMJ: 102563043(B3GAT3)
PSS: 102460502(B3GAT3)
CMY: 102941550(B3GAT3)
CPIC: 101940176(B3GAT3)
ACS: 100567109(b3gat3)
PVT: 110081006(B3GAT3)
PBI: 103057546(B3GAT3)
PMUR: 107292413(B3GAT3)
PMUA: 114586454(B3GAT3)
GJA: 107120072(B3GAT3)
XLA: 398597(b3gat3.L)
XTR: 594895(b3gat3)
NPR: 108794145(B3GAT3)
DRE: 192334(b3gat3)
SGH: 107563076 107588211(b3gat3)
IPU: 108268305(b3gat3)
PHYP: 113539858(b3gat3)
AMEX: 103028547(b3gat3)
EEE: 113579800(b3gat3)
TRU: 654312(b3gat3)
LCO: 104918106(b3gat3)
NCC: 104960743
MZE: 101480695(b3gat3)
ONL: 100690672(b3gat3)
OLA: 100049460(b3gat3)
XMA: 102238000(b3gat3)
XCO: 114157307(b3gat3)
PRET: 103480760(b3gat3)
CVG: 107098300(b3gat3)
NFU: 107377135(b3gat3)
KMR: 108242856(b3gat3)
ALIM: 106524984(b3gat3)
AOCE: 111577134(b3gat3)
CSEM: 103384246(b3gat3)
LCF: 108888787(b3gat3)
SDU: 111231304(b3gat3)
SLAL: 111666406(b3gat3)
HCQ: 109515067(b3gat3)
BPEC: 110156246(b3gat3)
MALB: 109965809(b3gat3)
SASA: 106578098(b3gat3)
OTW: 112264921
SALP: 112071457(b3gat3)
ELS: 105005687(b3gat3)
SFM: 108925220(b3gat3)
PKI: 111834547(b3gat3)
LCM: 102364764(B3GAT3)
CMK: 103171591(b3gat3)
RTP: 109923317
BFO: 118409812
SPU: 579023
APLC: 110981956
SKO: 100376501
DME: Dmel_CG32775(GlcAT-I)
DER: 6550975
DSE: 6612533
DSI: Dsimw501_GD16673(Dsim_GD16673)
DYA: Dyak_GE16334(Dyak_GlcAT-I)
DAN: 6503472
DSR: 110181804
DPE: 6596722
DMN: 108151945
DWI: 6653043
DAZ: 108618593
DNV: 108657103
DHE: 111593289
DVI: 6633777
MDE: 101892716
LCQ: 111678701
AAG: 5571591
AALB: 109429162
AME: 413271
BIM: 100741185
BTER: 100643292
CCAL: 108624399
OBB: 114878273
SOC: 105199644
MPHA: 105837929
AEC: 105151612
ACEP: 105617474
PBAR: 105430454
VEM: 105570196
HST: 105182746
DQU: 106745968
CFO: 105256002
LHU: 105676258
PGC: 109851697
OBO: 105284906
PCF: 106785162
NVI: 100123025(B3gat)
CSOL: 105363217
MDL: 103579755
TCA: 663511
DPA: 109545043
ATD: 109597949
NVL: 108567330
BMOR: 101743406
BMAN: 114240951
PMAC: 106708809
PRAP: 110998321
HAW: 110384556
TNL: 113495713
PXY: 105394656
API: 100159562
DNX: 107164038
AGS: 114130210
RMD: 113553674
BTAB: 109032291
CLEC: 106661064
ZNE: 110829492
FCD: 110850661
PVM: 113821710
TUT: 107368315
DPTE: 113794273
CSCU: 111620730
PTEP: 107447707
CEL: CELE_ZK1307.5(sqv-8)
CBR: CBG01067(Cbr-sqv-8)
BMY: Bm1_42955
CRG: 105326288
MYI: 110466531
OBI: 106873166
LAK: 106166698
SHX: MS3_09360
EGL: EGR_08995
HMG: 100200928
 » show all
Reference
  Authors
Ouzzine M, Gulberti S, Netter P, Magdalou J, Fournel-Gigleux S
  Title
Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization and functional activity are mediated by two crucial cysteine residues.
  Journal
J Biol Chem 275:28254-60 (2000)
DOI:10.1074/jbc.M002182200
  Sequence
[hsa:26229]
Reference
  Authors
Kim BT, Tsuchida K, Lincecum J, Kitagawa H, Bernfield M, Sugahara K
  Title
Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans. Two novel homologs exhibit broad specificity toward oligosaccharides from proteoglycans, glycoproteins, and glycosphingolipids.
  Journal
J Biol Chem 278:9116-24 (2003)
DOI:10.1074/jbc.M209344200
  Sequence
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