KEGG   ORTHOLOGY: K10226Help
Entry
K10226                      KO                                     

Name
FADS2
Definition
acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
Pathway
ko00592  alpha-Linolenic acid metabolism
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01212  Fatty acid metabolism
ko03320  PPAR signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00592 alpha-Linolenic acid metabolism
    K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase)
   01040 Biosynthesis of unsaturated fatty acids
    K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.3  acyl-CoA 6-desaturase
     K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase)
Lipid biosynthesis proteins [BR:ko01004]
 Desaturase
  Front-end
   K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase)
BRITE hierarchy
Other DBs
RN: R03814 R07861 R07933 R11110 R11111 R12167 R12168 R12170 R12171 R12172
GO: 0016213
Genes
HSA: 9415(FADS2)
PTR: 451244(FADS2)
PPS: 100980611(FADS2)
GGO: 101147055(FADS2) 109024898
PON: 100190814(FADS2)
NLE: 100596455(FADS2)
MCC: 719037(FADS2)
MCF: 101926688(FADS2)
CSAB: 103234245(FADS2)
RRO: 104679373(FADS2)
RBB: 108533600(FADS2)
CJC: 100387410(FADS2) 103796370
SBQ: 101051429(FADS2)
MMU: 56473(Fads2)
MCAL: 110285898(Fads2)
MPAH: 110322460(Fads2)
RNO: 83512(Fads2)
MUN: 110548092(Fads2)
CGE: 100757464(Fads2)
NGI: 103729125(Fads2)
HGL: 101726663(Fads2)
CCAN: 109695673(Fads2)
OCU: 100352712(FADS2)
TUP: 102475407(FADS2)
CFA: 483792(FADS2)
VVP: 112911087(FADS2)
AML: 100470289(FADS2)
UMR: 103678231(FADS2)
UAH: 113246983(FADS2)
ORO: 101364529(FADS2)
FCA: 101085071(FADS2)
PTG: 102968308(FADS2)
AJU: 106986967(FADS2)
BTA: 521822(FADS2)
BOM: 102275533(FADS2)
BIU: 109554370(FADS2)
BBUB: 102396145 102405983(FADS2)
PHD: 102315278(FADS2)
CHX: 100861212(FADS2) 102171133(FADS2)
OAS: 101108497 101108615(FADS2)
SSC: 444997(FADS2)
CFR: 102506325(FADS2) 102523732
CDK: 105091525(FADS2) 105104977
BACU: 103000252(FADS2)
LVE: 103083143(FADS2)
OOR: 101275563(FADS2)
DLE: 111183883(FADS2)
ECB: 100062709(FADS2)
EPZ: 103543786 103567043(FADS2)
EAI: 106847560(FADS2)
MYB: 102261893(FADS2)
MYD: 102773468(FADS2)
MNA: 107527684(FADS2)
HAI: 109390019(FADS2)
RSS: 109438876(FADS2)
DRO: 112317237(FADS2)
PALE: 102894063(FADS2)
LAV: 100677680
TMU: 101347025
MDO: 100009895(FADS2)
SHR: 100930034(FADS2)
PCW: 110195307(FADS2)
OAA: 100086288
GGA: 423122(FADS2)
MGP: 100549977(FADS2)
CJO: 107314439(FADS2)
APLA: 101798758(FADS2)
ACYG: 106033870
TGU: 100222881(FADS2)
LSR: 110484926(FADS2)
SCAN: 103822123
GFR: 102040567(FADS2)
FAB: 101810111(FADS2)
PHI: 102112585(FADS2)
PMAJ: 107205402(FADS2)
CCAE: 111930632
CCW: 104697641
ETL: 114067866
FPG: 101910606(FADS2)
FCH: 102058085(FADS2)
CLV: 102098615(FADS2)
EGZ: 104122147
NNI: 104009393(FADS2)
ACUN: 113481354
AAM: 106490046
ASN: 102382989
AMJ: 102563693(FADS2)
PSS: 102460236(FADS2)
CMY: 102933275(FADS2)
CPIC: 101936434
ACS: 100551818(fads2)
PVT: 110086191(FADS2)
PBI: 103050551(FADS2)
GJA: 107108854(FADS2)
XLA: 399058(fads2.S) 446688(fads2.L)
XTR: 100145314(fads2)
NPR: 108794176(FADS2)
DRE: 140615(fads2)
SRX: 107754339
IPU: 100305117(fads2) 108275104
AMEX: 103027972(fads2)
EEE: 113588191(fads2)
LCO: 104937137(fads2)
NCC: 104956187(fads2)
CSEM: 103380276(fads2)
LCF: 108886851(fads2)
SDU: 111229900(fads2)
HCQ: 109507604(fads2)
BPEC: 110167702(fads2)
SASA: 100136383(fadsd5) 100136441(fadsd6) 100329172(d6fadc) 100337624(d6fad_b) 106584797(D6fad_b) 106590822(D6fad_b)
OTW: 112264870
SALP: 112071110
ELS: 105018065(fads2)
SFM: 108921004(fads2) 108929076
LCM: 102349949(FADS2)
CMK: 103174861(fads2)
OBI: 106867675
SHX: MS3_06568
AQU: 100632154
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9867867
  Authors
Cho HP, Nakamura MT, Clarke SD
  Title
Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase.
  Journal
J Biol Chem 274:471-7 (1999)
DOI:10.1074/jbc.274.1.471
  Sequence
[hsa:9415] [mmu:56473]
LinkDB All DBs

KEGG   REACTION: R12167Help
Entry
R12167                      Reaction                               

Name
oleoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (6,7 cis-dehydrogenating)
Definition
Oleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (6Z,9Z)-Octadecadienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Equation
C00510 + 2 C00999 + C00007 + 2 C00080 <=> C21935 + 2 C00996 + 2 C00001
Enzyme
Pathway
rn01040  Biosynthesis of unsaturated fatty acids
rn01212  Fatty acid metabolism
Orthology
K10226  acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
LinkDB All DBs

DBGET integrated database retrieval system