KEGG   ORTHOLOGY: K10256Help
Entry
K10256                      KO                                     

Name
FAD2
Definition
omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.6 1.14.19.22]
Pathway
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01212  Fatty acid metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   01040 Biosynthesis of unsaturated fatty acids
    K10256  FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10256  FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.6  acyl-CoA (9+3)-desaturase
     K10256  FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase)
    1.14.19.22  acyl-lipid omega-6 desaturase (cytochrome b5)
     K10256  FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase)
Lipid biosynthesis proteins [BR:ko01004]
 Desaturase
  Omega
   K10256  FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase)
BRITE hierarchy
Other DBs
RN: R11043 R11044
GO: 0045485
Genes
BTAB: 109031516 109034286 109037327 109038609 109038610 109038611 109042365 109043360 109043386 109043387 109043419 109043487 109043488 109043505
EPA: 110243700
ADF: 107344154
PDAM: 113667909 113682750
SPIS: 111329485 111342409
ATH: AT3G12120(FAD2)
ALY: ARALYDRAFT_478568
CRB: 17890721
CSAT: 104745425 104764975 104776214
EUS: EUTSA_v10020910mg
BRP: 103870276(FAD2-1)
BOE: 106295108
RSZ: 108862913
CPAP: 110811677
CIT: 102627239
GMX: 100780912(GMFAD2-2D) 100805040(GMFAD2-2B) 100805777(FAD2-1B) 100809290(GMFAD2-2A) 102662570 547814(FAD2-1A) 547815(FAD2-2) 732617(FAD2-3)
LJA: Lj1g3v4317650.1(Lj1g3v4317650.1) Lj5g3v2237610.1(Lj5g3v2237610.1) Lj5g3v2237610.2(Lj5g3v2237610.2)
ZJU: 107432351
CSV: 101222623
CMO: 103486770
MCHA: 111024845
RCU: 8267086
JCU: 105646514
POP: 7479530
VVI: 100252129
SIND: 105159686 105163532(FAD2)
OSA: 4330523
DOSA: Os02t0716500-01(Os02g0716500) Os07t0416700-00(Os07g0416700)
OBR: 102719739
ATS: 109756354(LOC109756354) 109767804(LOC109767804) 109768827(LOC109768827) 109774922(LOC109774922) 109774938(LOC109774938) 109781985(LOC109781985)
ZMA: 100282744
PDA: 103713931
EGU: 105050201
MUS: 103980416
ATR: 18439780
MNG: MNEG_7806
ERC: Ecym_2769
TDL: TDEL_0E01510(TDEL0E01510)
PIC: PICST_72518(ODD1)
CAL: CAALFM_C601110WA(FAD2)
SLB: AWJ20_1033(ODE1)
NCR: NCU02209(ods)
NTE: NEUTE1DRAFT86398(NEUTE1DRAFT_86398)
MGR: MGG_01985
SSCK: SPSK_00128
MAW: MAC_06628
MAJ: MAA_07889
CMT: CCM_06866
ANI: AN1037.2
ANG: ANI_1_742074(An08g05160)
ABE: ARB_01637
TVE: TRV_05152
PTE: PTT_13901
CNE: CND02750
CNB: CNBD3600
LBC: LACBIDRAFT_292603(FAD12-5)
ABP: AGABI1DRAFT113988(AGABI1DRAFT_113988)
ABV: AGABI2DRAFT193825(AGABI2DRAFT_193825)
MGL: MGL_1345
MRT: MRET_4015
NGD: NGA_0081700(DES)
TCR: 429257.20
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7907506
  Authors
Okuley J, Lightner J, Feldmann K, Yadav N, Lark E, Browse J
  Title
Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis.
  Journal
Plant Cell 6:147-58 (1994)
DOI:10.1105/tpc.6.1.147
  Sequence
[ath:AT3G12120]
Reference
  Authors
Petrini GA, Altabe SG, Uttaro AD
  Title
Trypanosoma brucei oleate desaturase may use a cytochrome b5-like domain in another desaturase as an electron donor.
  Journal
Eur J Biochem 271:1079-86 (2004)
DOI:10.1111/j.1432-1033.2004.04005.x
  Sequence
Reference
  Authors
Kainou K, Kamisaka Y, Kimura K, Uemura H
  Title
Isolation of Delta12 and omega3-fatty acid desaturase genes from the yeast Kluyveromyces lactis and their heterologous expression to produce linoleic and alpha-linolenic acids in Saccharomyces cerevisiae.
  Journal
Yeast 23:605-12 (2006)
DOI:10.1002/yea.1378
  Sequence
LinkDB All DBs

KEGG   ORTHOLOGY: K22993Help
Entry
K22993                      KO                                     

Name
K22993
Definition
bifunctional Delta-12/omega-3 fatty acid desaturase [EC:1.14.19.6 1.14.19.-]
Pathway
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01212  Fatty acid metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   01040 Biosynthesis of unsaturated fatty acids
    K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.6  acyl-CoA (9+3)-desaturase
     K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase
    1.14.19.-  
     K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase
BRITE hierarchy
Other DBs
RN: R12205
GO: 0045485 0042389
Genes
NCR: NCU09497
NTE: NEUTE1DRAFT116751(NEUTE1DRAFT_116751)
SMP: SMAC_07882
PAN: PODANSg2430
MTM: MYCTH_50837
CTHR: CTHT_0071750
MGR: MGG_08474
TMN: UCRPA7_3220
SSCK: SPSK_07620
FGR: FGSG_07890
CMT: CCM_09560
ANI: AN7204.2
ANG: ANI_1_962124(An14g06980)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Damude HG, Zhang H, Farrall L, Ripp KG, Tomb JF, Hollerbach D, Yadav NS
  Title
Identification of bifunctional delta12/omega3 fatty acid desaturases for improving the ratio of omega3 to omega6 fatty acids in microbes and plants.
  Journal
Proc Natl Acad Sci U S A 103:9446-51 (2006)
DOI:10.1073/pnas.0511079103
  Sequence
LinkDB All DBs

KEGG   REACTION: R11043Help
Entry
R11043                      Reaction                               

Name
oleoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (12,13 cis-dehydrogenating)
Definition
Oleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Linoleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Equation
C00510 + 2 C00999 + C00007 + 2 C00080 <=> C02050 + 2 C00996 + 2 C00001
Reaction class
RC00917  C00510_C02050
Enzyme
Pathway
rn01040  Biosynthesis of unsaturated fatty acids
rn01212  Fatty acid metabolism
Orthology
K10256  omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.6 1.14.19.22]
Other DBs
RHEA: 25859
LinkDB All DBs

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