KEGG   ORTHOLOGY: K10258Help
Entry
K10258                      KO                                     

Name
TER, TSC13, CER10
Definition
very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
Pathway
ko00062  Fatty acid elongation
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01212  Fatty acid metabolism
Module
M00415  Fatty acid elongation in endoplasmic reticulum
Disease
H00768  Autosomal recessive mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
   01040 Biosynthesis of unsaturated fatty acids
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.93  very-long-chain enoyl-CoA reductase
     K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Component type
   K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
BRITE hierarchy
Other DBs
RN: R07761 R09449 R10828
Genes
HSA: 9524(TECR)
PTR: 455786(TECR)
PPS: 100971383(TECR)
GGO: 101140023(TECR) 109025468
PON: 100440904(TECR)
NLE: 100581652(TECR)
MCC: 718928(TECR)
MCF: 101926702(TECR)
CSAB: 103234044(TECR)
RRO: 104661039(TECR)
RBB: 108514773(TECR)
CJC: 100402213(TECR)
SBQ: 101033875(TECR)
MMU: 106529(Tecr)
MCAL: 110300213(Tecr)
MPAH: 110337246(Tecr)
RNO: 191576(Tecr)
MUN: 110545857(Tecr)
CGE: 100761652(Tecr)
NGI: 103751841(Tecr)
HGL: 101716060(Tecr)
CCAN: 109686636(Tecr)
OCU: 103346023(TECR)
TUP: 102480210(TECR)
CFA: 476687(TECR)
VVP: 112908161(TECR)
AML: 100467030(TECR)
UMR: 103682180(TECR)
UAH: 113247156(TECR)
ORO: 101386071(TECR)
FCA: 101091601(TECR)
PTG: 102948536 102959844(TECR)
AJU: 106986213(TECR)
BTA: 614105(TECR)
BOM: 102285957(TECR)
BIU: 109561491(TECR)
BBUB: 102397352(TECR)
PHD: 102340071(TECR)
CHX: 102187120(TECR)
OAS: 101117331(TECR)
SSC: 100515709(TECR)
CFR: 102519742(TECR)
CDK: 105105973(TECR)
BACU: 102997227(TECR)
LVE: 103070891(TECR)
OOR: 101269817(TECR)
DLE: 111166579(TECR)
ECB: 100065024(TECR)
EPZ: 103565661(TECR)
EAI: 106844303(TECR)
MYB: 102260613(TECR)
MYD: 102751823(TECR)
MNA: 107542369(TECR)
HAI: 109394266(TECR)
RSS: 109442713 109454938(TECR)
DRO: 112301386(TECR)
PALE: 102887858(TECR)
LAV: 100674918(TECR)
TMU: 101348735
MDO: 100026440(TECR) 100032861
SHR: 100914010(TECR)
PCW: 110197969 110203436(TECR)
OAA: 100080249 100081999(TECR)
GGA: 107050163 424491(TECR)
MGP: 100545685(TECR)
CJO: 107307749(TECR) 107317393
APLA: 101799511(TECR)
ACYG: 106039444(TECR)
TGU: 100230168(TECR)
LSR: 110468229(TECR)
SCAN: 103815135(TECR)
GFR: 102032504(TECR)
FAB: 101810425(TECR) 101812411
PHI: 102099600(TECR) 106628096
CCAE: 111922653(TECR) 111932652
CCW: 104695353(TECR)
ETL: 114055627(TECR)
FCH: 102049843(TECR)
CLV: 110363827(TECR)
EGZ: 104134018(TECR)
ACUN: 113482866(TECR)
AAM: 106484788 106499774(TECR)
ASN: 102370679(TECR) 102383204
AMJ: 102559187(TECR) 102575131
PSS: 102457301(TECR) 102459125
CMY: 102929357(TECR) 102931932
CPIC: 101937001(TECR) 101945886
ACS: 100560578 100566730(tecr)
PVT: 110070802(TECR) 110076484
PBI: 103058993 103065171(TECR)
PMUR: 107292471(TECR) 107295608
GJA: 107112228 107117643(TECR)
XLA: 108713542 380153(gpsn2) 444160(tecr.L)
XTR: 493561(tecr) 780081
NPR: 108789250 108797751(TECR)
DRE: 326954(tecrb) 566085(tecra) 798606(tecrl2a)
KMR: 108241336 108241483(tecr)
HCQ: 109521419 109527436(tecr)
MALB: 109952401(tecr) 109966006
CMK: 103174648 103191170(tecr)
CIN: 100183960
SPU: 576023
DME: Dmel_CG10849(Sc2)
DER: 6546239
DPE: 6601109
DSI: Dsimw501_GD13786(Dsim_GD13786)
DWI: 6643043
DAZ: 108613041
DNV: 108652307
DHE: 111596861
MDE: 101887858
AAG: 5570994
AME: 725146
BIM: 100747299
BTER: 100644169
SOC: 105193039
MPHA: 105834618
AEC: 105153980
ACEP: 105618040
PBAR: 105433004
HST: 105181228
DQU: 106746495
CFO: 105259215
LHU: 105673344
PGC: 109859407
OBO: 105282481
PCF: 106791875
MDL: 103579818
TCA: 659815
DPA: 109537890
NVL: 108567063
BMOR: 101742899
PMAC: 106718707
PRAP: 110995799
HAW: 110375119
TNL: 113496889
PXY: 105385206
API: 100160468
AGS: 114122650
CLEC: 106664306
ZNE: 110835131
FCD: 110859769
TUT: 107369209
CEL: CELE_C15F1.6(art-1)
CBR: CBG11196(Cbr-art-1)
BMY: Bm1_42555
TSP: Tsp_07269
PCAN: 112573754
CRG: 105326706
MYI: 110461543
OBI: 106878132
LAK: 106164649
SHX: MS3_09546
EGL: EGR_03533
AQU: 100640363
ATH: AT3G55360(CER10)
ALY: ARALYDRAFT_906954(ATTSC13)
CRB: 17884738
TCC: 18586099
EGR: 104454293
CAM: 101496420 101508101(sr5a)
LJA: Lj0g3v0067399.1(Lj0g3v0067399.1) Lj0g3v0067409.1(Lj0g3v0067409.1)
PPER: 18784679
PMUM: 103332647
PAVI: 110756623
ZJU: 107413483
CSV: 101213758
CMO: 103498153
JCU: 105647736
VVI: 100266766
DCR: 108210643
SOE: 110794839
NNU: 104594555
OSA: 4324516
DOSA: Os01t0150000-01(Os01g0150000)
ATS: 109777279(LOC109777279)
SBI: 8060800
ZMA: 100191179(AY106269) 103633692
EGU: 105052214
MNG: MNEG_5026
APRO: F751_1654
SCE: YDL015C(TSC13)
ERC: Ecym_5259
KMX: KLMA_10196(TSC13)
NCS: NCAS_0I01880(NCAS0I01880)
NDI: NDAI_0A06480(NDAI0A06480)
TPF: TPHA_0A04340(TPHA0A04340)
TBL: TBLA_0B01660(TBLA0B01660)
TDL: TDEL_0D04380(TDEL0D04380)
KAF: KAFR_0F02320(KAFR0F02320)
PIC: PICST_39084(TSC13)
CAL: CAALFM_C101050CA(CaO19.3293)
SLB: AWJ20_1731(TSC13)
NCR: NCU03362
NTE: NEUTE1DRAFT117529(NEUTE1DRAFT_117529)
MGR: MGG_03250
SSCK: SPSK_00299
MAW: MAC_05645
MAJ: MAA_01851
CMT: CCM_05177
MBE: MBM_02606
ANI: AN1968.2
ANG: ANI_1_968184(An04g05930)
ABE: ARB_02271
TVE: TRV_04982
PNO: SNOG_07392(SNOG_07391)
PTE: PTT_16464
CNE: CNE01780
CNB: CNBE1760
MGL: MGL_0166
DDI: DDB_G0270270(gpsn2)
DFA: DFA_02956(gpsn2)
EHI: EHI_045030(3.t00089)
PYO: PY17X_0914200(PY03009)
PCB: PCHAS_071400(PC000427.01.0)
TAN: TA18840
TPV: TP03_0656
BBO: BBOV_III001830(17.m10668)
CPV: cgd2_1200
SPAR: SPRG_07122
TCR: 457251.10
LMA: LMJF_25_1770(EnCR)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kohlwein SD, Eder S, Oh CS, Martin CE, Gable K, Bacikova D, Dunn T
  Title
Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.
  Journal
Mol Cell Biol 21:109-25 (2001)
DOI:10.1128/MCB.21.1.109-125.2001
  Sequence
[sce:YDL015C]
Reference
  Authors
Gable K, Garton S, Napier JA, Dunn TM
  Title
Functional characterization of the Arabidopsis thaliana orthologue of Tsc13p, the enoyl reductase of the yeast microsomal fatty acid elongating system.
  Journal
J Exp Bot 55:543-5 (2004)
DOI:10.1093/jxb/erh061
  Sequence
[ath:AT3G55360]
Reference
PMID:12482854 (H.sapiens)
  Authors
Moon YA, Horton JD.
  Title
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.
  Journal
J Biol Chem 278:7335-43 (2003)
DOI:10.1074/jbc.M211684200
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