KEGG   ORTHOLOGY: K10351
Entry
K10351                      KO                                     

Name
MYL2
Definition
myosin regulatory light chain 2
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04371  Apelin signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
ko05410  Hypertrophic cardiomyopathy
ko05414  Dilated cardiomyopathy
Disease
H00292  Hypertrophic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K10351  MYL2; myosin regulatory light chain 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10351  MYL2; myosin regulatory light chain 2
   04530 Tight junction
    K10351  MYL2; myosin regulatory light chain 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K10351  MYL2; myosin regulatory light chain 2
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K10351  MYL2; myosin regulatory light chain 2
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K10351  MYL2; myosin regulatory light chain 2
   04261 Adrenergic signaling in cardiomyocytes
    K10351  MYL2; myosin regulatory light chain 2
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K10351  MYL2; myosin regulatory light chain 2
   05414 Dilated cardiomyopathy
    K10351  MYL2; myosin regulatory light chain 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K10351  MYL2; myosin regulatory light chain 2
   05131 Shigellosis
    K10351  MYL2; myosin regulatory light chain 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K10351  MYL2; myosin regulatory light chain 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K10351  MYL2; myosin regulatory light chain 2
Genes
HSA: 4633(MYL2)
PTR: 452243(MYL2)
PPS: 100973169(MYL2)
GGO: 101146701(MYL2)
PON: 100462280(MYL2)
NLE: 100590389(MYL2)
MCC: 711937(MYL2)
MCF: 102147025(MYL2)
CSAB: 103239122(MYL2)
RRO: 104674641(MYL2)
RBB: 108512247(MYL2)
CJC: 100408790(MYL2)
SBQ: 101050353(MYL2)
MMU: 17906(Myl2)
MCAL: 110294798(Myl2)  
MPAH: 110312960(Myl2)
RNO: 363925(Myl2)
MUN: 110545344(Myl2)
CGE: 100773969(Myl2)
NGI: 103745580(Myl2)
HGL: 101713909(Myl2) 101714346
CCAN: 109685543
OCU: 100353304(MYL2)
TUP: 102502505(MYL2)
CFA: 403614(MYL2)
VVP: 112935243(MYL2)  
AML: 100483724(MYL2)
UMR: 103661279(MYL2)
UAH: 113267112(MYL2)
ORO: 101385566(MYL2)
ELK: 111156317
FCA: 101101169(MYL2)
PTG: 102954811(MYL2)  
PPAD: 109277655(MYL2)
AJU: 106967527(MYL2)
BTA: 505519(MYL2)
BOM: 102275987(MYL2)
BIU: 109571417(MYL2)
BBUB: 102393988(MYL2)
CHX: 102179873(MYL2)
OAS: 100196904(MYL2)
SSC: 396690(MYL2)
CFR: 102509636(MYL2)
CDK: 105102482(MYL2)
BACU: 103016555(MYL2)
LVE: 103077775(MYL2)
OOR: 101287240(MYL2)
DLE: 111187002(MYL2)
PCAD: 102983557(MYL2)
ECB: 100147688(MYL2)
EPZ: 103544050
EAI: 106842271(MYL2)
MYB: 102258260(MYL2)
MYD: 102754925(MYL2)
MNA: 107529566(MYL2)
PALE: 102888244(MYL2)  
RAY: 107513248(MYL2)
MJV: 108400560(MYL2)
TMU: 101351770
MDO: 100019715(MYL2)
SHR: 100917142(MYL2)
PCW: 110196868(MYL2)
OAA: 100074559(MYL2)
GGA: 416874(MYL2)
MGP: 100547128(MYL2)
CJO: 107321507(MYL2)
NMEL: 110406487(MYL2)  
ACYG: 106031114(MYL2)
TGU: 100223766(MYL2)
LSR: 110478104(MYL2)
SCAN: 103818146(MYL2)
GFR: 102032391(MYL2)
FAB: 101808099(MYL2)
PHI: 102101963(MYL2)
PMAJ: 107211518(MYL2)
CCAE: 111936417(MYL2)
CCW: 104688679(MYL2)
ETL: 114062679(MYL2)
FPG: 101916533(MYL2)
FCH: 102046529(MYL2)
EGZ: 104122714(MYL2)
NNI: 104019401(MYL2)
ACUN: 113486078(MYL2)
PADL: 103914543(MYL2)
AAM: 106495672(MYL2)
ASN: 102375176(MYL2)
AMJ: 102563829(MYL2)
PSS: 102449621(MYL2)
CMY: 102937866
CPIC: 101931587(MYL2)
ACS: 100566191(myl2)
PVT: 110083871(MYL2)
PBI: 103055734(MYL2)
PMUR: 107286997(MYL2)
TSR: 106548632(MYL2)
PMUA: 114602734(MYL2)
GJA: 107112184(MYL2)
XLA: 108697104 447131(myl2.S)
XTR: 100135705(myl2)
NPR: 108788538(MYL2)
DRE: 100537244(myl2a) 677750(myl2b)
NCC: 104965458(myl2)
KMR: 108239856
CSEM: 103386220 103397433(myl2)
HCQ: 109522138
SALP: 111964589
ELS: 105017044
SFM: 108933343(myl2)
PKI: 111842153(myl2)
LCM: 102362592(MYL2)
CMK: 103184326(myl2)  
RTP: 109935120
NVI: 100115182
 » show all
Reference
  Authors
Stevens L, Bastide B, Hedou J, Cieniewski-Bernard C, Montel V, Cochon L, Dupont E, Mounier Y
  Title
Potential regulation of human muscle plasticity by MLC2 post-translational modifications during bed rest and countermeasures.
  Journal
Arch Biochem Biophys 540:125-32 (2013)
DOI:10.1016/j.abb.2013.10.016
Reference
PMID:2704627
  Authors
Dalla Libera L, Hoffmann E, Floroff M, Jackowski G
  Title
Isolation and nucleotide sequence of the cDNA encoding human ventricular myosin light chain 2.
  Journal
Nucleic Acids Res 17:2360 (1989)
DOI:10.1093/nar/17.6.2360
  Sequence
[hsa:4633]
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