KEGG   ORTHOLOGY: K10351
Entry
K10351                      KO                                     

Name
MYL2
Definition
myosin regulatory light chain 2
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04371  Apelin signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
ko05410  Hypertrophic cardiomyopathy
ko05414  Dilated cardiomyopathy
Disease
H00292  Hypertrophic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K10351  MYL2; myosin regulatory light chain 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10351  MYL2; myosin regulatory light chain 2
   04530 Tight junction
    K10351  MYL2; myosin regulatory light chain 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K10351  MYL2; myosin regulatory light chain 2
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K10351  MYL2; myosin regulatory light chain 2
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K10351  MYL2; myosin regulatory light chain 2
   04261 Adrenergic signaling in cardiomyocytes
    K10351  MYL2; myosin regulatory light chain 2
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K10351  MYL2; myosin regulatory light chain 2
   05414 Dilated cardiomyopathy
    K10351  MYL2; myosin regulatory light chain 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K10351  MYL2; myosin regulatory light chain 2
   05131 Shigellosis
    K10351  MYL2; myosin regulatory light chain 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K10351  MYL2; myosin regulatory light chain 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K10351  MYL2; myosin regulatory light chain 2
Genes
HSA: 4633(MYL2)
PTR: 452243(MYL2)
PPS: 100973169(MYL2)
GGO: 101146701(MYL2)
PON: 100462280(MYL2)
NLE: 100590389(MYL2)
MCC: 711937(MYL2)
MCF: 102147025(MYL2)
CSAB: 103239122(MYL2)
RRO: 104674641(MYL2)
RBB: 108512247(MYL2)
CJC: 100408790(MYL2)
SBQ: 101050353(MYL2)
MMU: 17906(Myl2)
MCAL: 110294798(Myl2)
MPAH: 110312960(Myl2)
RNO: 363925(Myl2)
MUN: 110545344(Myl2)
CGE: 100773969(Myl2)
NGI: 103745580(Myl2)
HGL: 101713909(Myl2) 101714346
CCAN: 109685543
OCU: 100353304(MYL2)
TUP: 102502505(MYL2)
CFA: 403614(MYL2)
VVP: 112935243(MYL2)
AML: 100483724(MYL2)
UMR: 103661279(MYL2)
UAH: 113267112(MYL2)
ORO: 101385566(MYL2)
ELK: 111156317
FCA: 101101169(MYL2)
PTG: 102954811(MYL2)
PPAD: 109277655(MYL2)
AJU: 106967527(MYL2)
BTA: 505519(MYL2)
BOM: 102275987(MYL2)
BIU: 109571417(MYL2)
BBUB: 102393988(MYL2)
CHX: 102179873(MYL2)
OAS: 100196904(MYL2)
SSC: 396690(MYL2)
CFR: 102509636(MYL2)
CDK: 105102482(MYL2)
BACU: 103016555(MYL2)
LVE: 103077775(MYL2)
OOR: 101287240(MYL2)
DLE: 111187002(MYL2)
PCAD: 102983557(MYL2)
ECB: 100147688(MYL2)
EPZ: 103544050
EAI: 106842271(MYL2)
MYB: 102258260(MYL2)
MYD: 102754925(MYL2)
MNA: 107529566(MYL2)
PALE: 102888244(MYL2)
RAY: 107513248(MYL2)
MJV: 108400560(MYL2)
TMU: 101351770
MDO: 100019715(MYL2)
SHR: 100917142(MYL2)
PCW: 110196868(MYL2)
OAA: 100074559(MYL2)
GGA: 416874(MYL2)
MGP: 100547128(MYL2)
CJO: 107321507(MYL2)
NMEL: 110406487(MYL2)
ACYG: 106031114(MYL2)
TGU: 100223766(MYL2)
LSR: 110478104(MYL2)
SCAN: 103818146(MYL2)
GFR: 102032391(MYL2)
FAB: 101808099(MYL2)
PHI: 102101963(MYL2)
PMAJ: 107211518(MYL2)
CCAE: 111936417(MYL2)
CCW: 104688679(MYL2)
ETL: 114062679(MYL2)
FPG: 101916533(MYL2)
FCH: 102046529(MYL2)
EGZ: 104122714(MYL2)
NNI: 104019401(MYL2)
ACUN: 113486078(MYL2)
PADL: 103914543(MYL2)
AAM: 106495672(MYL2)
ASN: 102375176(MYL2)
AMJ: 102563829(MYL2)
PSS: 102449621(MYL2)
CMY: 102937866
CPIC: 101931587(MYL2)
ACS: 100566191(myl2)
PVT: 110083871(MYL2)
PBI: 103055734(MYL2)
PMUR: 107286997(MYL2)
TSR: 106548632(MYL2)
PMUA: 114602734(MYL2)
GJA: 107112184(MYL2)
XLA: 108697104 447131(myl2.S)
XTR: 100135705(myl2)
NPR: 108788538(MYL2)
DRE: 100537244(myl2a) 677750(myl2b)
NCC: 104965458(myl2)
NFU: 107385499
KMR: 108239856
CSEM: 103386220 103397433(myl2)
HCQ: 109522138
BPEC: 110153909
SALP: 111964589
ELS: 105017044
SFM: 108933343(myl2)
PKI: 111842153(myl2)
LCM: 102362592(MYL2)
CMK: 103184326(myl2)
RTP: 109935120
NVI: 100115182
 » show all
Reference
  Authors
Stevens L, Bastide B, Hedou J, Cieniewski-Bernard C, Montel V, Cochon L, Dupont E, Mounier Y
  Title
Potential regulation of human muscle plasticity by MLC2 post-translational modifications during bed rest and countermeasures.
  Journal
Arch Biochem Biophys 540:125-32 (2013)
DOI:10.1016/j.abb.2013.10.016
Reference
PMID:2704627
  Authors
Dalla Libera L, Hoffmann E, Floroff M, Jackowski G
  Title
Isolation and nucleotide sequence of the cDNA encoding human ventricular myosin light chain 2.
  Journal
Nucleic Acids Res 17:2360 (1989)
DOI:10.1093/nar/17.6.2360
  Sequence
[hsa:4633]
LinkDB

KEGG   ORTHOLOGY: K12753
Entry
K12753                      KO                                     

Name
MYL5
Definition
myosin regulatory light chain 5
Pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12753  MYL5; myosin regulatory light chain 5
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12753  MYL5; myosin regulatory light chain 5
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K12753  MYL5; myosin regulatory light chain 5
  09158 Development and regeneration
   04360 Axon guidance
    K12753  MYL5; myosin regulatory light chain 5
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12753  MYL5; myosin regulatory light chain 5
   05131 Shigellosis
    K12753  MYL5; myosin regulatory light chain 5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12753  MYL5; myosin regulatory light chain 5
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12753  MYL5; myosin regulatory light chain 5
Genes
HSA: 4636(MYL5)
PTR: 750383(MYL5)
PPS: 100983944(MYL5)
GGO: 101125422(MYL5)
PON: 100455740(MYL5)
NLE: 100594437(MYL5)
MCC: 697765(MYL5)
MCF: 102125369(MYL5)
CSAB: 103246516(MYL5)
RRO: 104671717(MYL5)
RBB: 108524384(MYL5)
CJC: 100390114(MYL5)
NGI: 103728712(Myl5)
CCAN: 109693856(Myl5)
TUP: 102494842(MYL5)
CFA: 479135(MYL5)
VVP: 112918704(MYL5)
AML: 100480867(MYL5)
UMR: 103676847(MYL5)
UAH: 113245725(MYL5)
ORO: 101362115(MYL5)
FCA: 493974(MYL5)
PTG: 102958022(MYL5)
PPAD: 109259322(MYL5)
AJU: 106981837(MYL5)
SSC: 100625329(MYL5)
CFR: 102509719(MYL5)
CDK: 105100801(MYL5)
BACU: 103018404(MYL5)
OOR: 101270012(MYL5)
DLE: 111164877(MYL5)
PCAD: 102985354(MYL5)
ECB: 100051591(MYL5)
EPZ: 103566770
EAI: 106825418(MYL5)
MYB: 102256586(MYL5)
MYD: 102753435(MYL5)
MNA: 107524124(MYL5)
HAI: 109390950(MYL5)
DRO: 112316654(MYL5)
PALE: 102880875(MYL5)
RAY: 107518021(MYL5)
LAV: 100654026(MYL5)
TMU: 101343534
MDO: 100027358(MYL5)
SHR: 100931952(MYL5)
PCW: 110221051(MYL5)
OAA: 100083806(MYL5)
AAM: 106482513(MYL5)
ASN: 102369711(MYL5)
AMJ: 102564332(MYL5)
PSS: 102457241(MYL5)
CMY: 102943468
CPIC: 101944689(MYL5)
ACS: 100560522(myl5)
PVT: 110070312(MYL5)
PBI: 103060382(MYL5)
PMUR: 107292177(MYL5)
TSR: 106549692(MYL5)
PMUA: 114587600(MYL5)
GJA: 107117236(MYL5)
IPU: 100528893(myl5)
PHYP: 113543209
AMEX: 111191483
EEE: 113570755
LCO: 104939604
CSEM: 103390377
POV: 109647679
LCF: 108892278
SDU: 111238024
BPEC: 110161518
SASA: 106563297
SALP: 111962831
SFM: 108935197
PKI: 111842232(myl5)
LCM: 102348633(MYL5)
CMK: 103187953(myl5)
RTP: 109933356(myl5)
 » show all
Reference
PMID:1284596
  Authors
Collins C, Schappert K, Hayden MR
  Title
The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates.
  Journal
Hum Mol Genet 1:727-33 (1992)
  Sequence
[hsa:4636]
LinkDB

KEGG   ORTHOLOGY: K12754
Entry
K12754                      KO                                     

Name
MYL7
Definition
myosin regulatory light chain 7
Pathway
ko04510  Focal adhesion
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12754  MYL7; myosin regulatory light chain 7
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12754  MYL7; myosin regulatory light chain 7
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K12754  MYL7; myosin regulatory light chain 7
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12754  MYL7; myosin regulatory light chain 7
   05131 Shigellosis
    K12754  MYL7; myosin regulatory light chain 7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12754  MYL7; myosin regulatory light chain 7
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12754  MYL7; myosin regulatory light chain 7
Genes
HSA: 58498(MYL7)
PTR: 463920(MYL7)
PPS: 100981324(MYL7)
GGO: 101139698(MYL7)
PON: 112134321(MYL7)
NLE: 100589180(MYL7)
MCC: 707293(MYL7)
MCF: 102127232(MYL7)
CSAB: 103226143(MYL7)
RRO: 104671143(MYL7)
RBB: 108544023(MYL7)
CJC: 100409034(MYL7)
SBQ: 101027671(MYL7)
MMU: 17898(Myl7)
MCAL: 110305591(Myl7)
MPAH: 110330683(Myl7)
RNO: 289759(Myl7)
MUN: 110546082(Myl7)
CGE: 100768927(Myl7)
NGI: 103734981(Myl7)
HGL: 101721307(Myl7)
CCAN: 109685902(Myl7)
TUP: 102491716(MYL7)
CFA: 100683291(MYL7)
VVP: 112911687(MYL7)
AML: 100475493(MYL7)
UMR: 103674685(MYL7)
UAH: 113265885(MYL7)
ORO: 101383534(MYL7)
FCA: 101095326(MYL7)
PTG: 102965729(MYL7)
PPAD: 109267914(MYL7)
AJU: 106968238(MYL7)
BTA: 508257(MYL7)
BOM: 102277500(MYL7)
BIU: 109557919(MYL7)
BBUB: 102398108(MYL7)
CHX: 102185710(MYL7)
OAS: 101117156(MYL7)
SSC: 100514437(MYL7)
CFR: 102524212(MYL7)
CDK: 105092329(MYL7)
LVE: 103074641(MYL7)
OOR: 101287277(MYL7)
DLE: 111184514(MYL7)
PCAD: 102975231(MYL7)
ECB: 100065012(MYL7)
EPZ: 103554942(MYL7)
EAI: 106822920(MYL7)
MYB: 102247805(MYL7)
MYD: 102752867(MYL7)
MNA: 107542067(MYL7)
HAI: 109373005(MYL7)
DRO: 112306911(MYL7)
PALE: 102888738(MYL7)
RAY: 107512384(MYL7)
MJV: 108394026(MYL7)
LAV: 100657954(MYL7)
TMU: 101346602
MDO: 100030115(MYL7)
SHR: 100917903(MYL7)
PCW: 110206410(MYL7)
OAA: 100091153 114815109(MYL7)
NNI: 104022604(MYL7)
AAM: 106483926
ASN: 102382424(MYL7)
AMJ: 102562442(MYL7)
PSS: 102457458(MYL7)
CMY: 102932535(MYL7)
CPIC: 101935433(MYL7)
ACS: 100567011(myl7)
PVT: 110084339(MYL7)
PBI: 103062019(MYL7)
PMUR: 107286245(MYL7)
PMUA: 114585940(MYL7)
GJA: 107117400(MYL7)
XLA: 108712731(myl7.S) 380007(mylc2a)
XTR: 100135145(myl7)
NPR: 108796071(MYL7)
DRE: 30592(myl7)
IPU: 108265071(myl7)
PHYP: 113546002(myl7)
AMEX: 103025855(myl7)
EEE: 113588676(myl7)
TRU: 105418036
LCO: 104922971(myl7)
NCC: 104956792(myl7)
OLA: 100271916(myl7)
XMA: 102229585(myl7)
XCO: 114154123(myl7)
PRET: 103470002(myl7)
CVG: 107089654(myl7)
NFU: 107394280(myl7)
KMR: 108233671(myl7)
ALIM: 106519910(myl7)
AOCE: 111567819(myl7)
CSEM: 103397746(myl7)
POV: 109637068(myl7)
LCF: 108881388(myl7)
SDU: 111236479(myl7)
SLAL: 111654894(myl7)
HCQ: 109526348(myl7)
BPEC: 110157044(myl7)
MALB: 109956572(myl7)
SASA: 106580582 106585166(myl7)
OTW: 112249714
ELS: 105014409(myl7)
SFM: 108940356(myl7)
PKI: 111857527(myl7)
LCM: 102364976(MYL7)
CMK: 103187780(myl7)
RTP: 109932924(myl7)
 » show all
Reference
  Authors
Kovacs M, Wang F, Hu A, Zhang Y, Sellers JR
  Title
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform.
  Journal
J Biol Chem 278:38132-40 (2003)
DOI:10.1074/jbc.M305453200
  Sequence
[hsa:58498]
LinkDB

KEGG   ORTHOLOGY: K12755
Entry
K12755                      KO                                     

Name
MYL9
Definition
myosin regulatory light chain 9
Pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04270  Vascular smooth muscle contraction
ko04360  Axon guidance
ko04510  Focal adhesion
ko04530  Tight junction
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko04921  Oxytocin signaling pathway
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K12755  MYL9; myosin regulatory light chain 9
   04022 cGMP-PKG signaling pathway
    K12755  MYL9; myosin regulatory light chain 9
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12755  MYL9; myosin regulatory light chain 9
   04530 Tight junction
    K12755  MYL9; myosin regulatory light chain 9
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12755  MYL9; myosin regulatory light chain 9
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K12755  MYL9; myosin regulatory light chain 9
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K12755  MYL9; myosin regulatory light chain 9
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K12755  MYL9; myosin regulatory light chain 9
  09158 Development and regeneration
   04360 Axon guidance
    K12755  MYL9; myosin regulatory light chain 9
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12755  MYL9; myosin regulatory light chain 9
   05131 Shigellosis
    K12755  MYL9; myosin regulatory light chain 9
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12755  MYL9; myosin regulatory light chain 9
   04147 Exosome
    K12755  MYL9; myosin regulatory light chain 9
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12755  MYL9; myosin regulatory light chain 9
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   K12755  MYL9; myosin regulatory light chain 9
Genes
HSA: 10398(MYL9)
PTR: 458216(MYL9)
PPS: 100995742(MYL9)
GGO: 101138103(MYL9)
PON: 100172462(MYL9)
NLE: 100593242(MYL9)
MCC: 709784(MYL9)
MCF: 102135642(MYL9)
CSAB: 103216486(MYL9)
RRO: 104680548(MYL9)
RBB: 108523051(MYL9)
CJC: 100402498 100409239(MYL9)
SBQ: 101037608(MYL9) 101040386
MMU: 98932(Myl9)
MCAL: 110285279(Myl9)
MPAH: 110318312(Myl9)
RNO: 296313(Myl9)
MUN: 110556939(Myl9)
CGE: 100753477(Myl9)
NGI: 103740213(Myl9) 103748521
HGL: 101716487(Myl9)
CCAN: 109700175
OCU: 100343384(MYL9)
TUP: 102483320(MYL9)
CFA: 485856(MYL9)
VVP: 112928190(MYL9)
AML: 100465571(MYL9)
UMR: 103669791(MYL9)
UAH: 113258556(MYL9)
ORO: 101362788(MYL9)
ELK: 111141363
FCA: 101097882(MYL9)
PTG: 102964789(MYL9)
PPAD: 109272490(MYL9)
AJU: 106979297(MYL9)
BTA: 505964(MYL9)
BOM: 102265044(MYL9)
BIU: 109567416(MYL9)
BBUB: 102390609(MYL9)
CHX: 102178087(MYL9)
OAS: 101121534(MYL9)
SSC: 100157760(MYL9)
CFR: 102517225(MYL9)
CDK: 105084979(MYL9)
BACU: 103009483(MYL9)
LVE: 103077228(MYL9)
OOR: 101270950(MYL9)
DLE: 111184217(MYL9)
PCAD: 102985793(MYL9)
ECB: 100055199(MYL9)
EPZ: 103557622(MYL9)
EAI: 106835045(MYL9)
MYD: 102752273(MYL9) 102769087
MNA: 107542167(MYL9) 107544330
HAI: 109389577(MYL9)
DRO: 112303838(MYL9)
PALE: 102886777(MYL9)
RAY: 107512613(MYL9)
MJV: 108387031(MYL9)
LAV: 100672436(MYL9)
TMU: 101346277
MDO: 100028971(MYL9)
SHR: 100917897(MYL9)
PCW: 110216721(MYL9)
OAA: 100073924(MYL9)
GGA: 396215(MYL9)
MGP: 100549745(MYL9)
CJO: 107322805(MYL9)
NMEL: 110408206(MYL9)
APLA: 101799368(MYL9)
ACYG: 106045436(MYL9)
TGU: 100230189(MYL9)
LSR: 110473783(MYL9)
SCAN: 103823660(MYL9)
GFR: 102045323(MYL9)
FAB: 101818675(MYL9)
PHI: 102114384(MYL9)
PMAJ: 107213424(MYL9)
CCAE: 111938346(MYL9)
CCW: 104698028(MYL9)
ETL: 114059723(MYL9)
FPG: 101911603
FCH: 102048471(MYL9)
CLV: 102095544(MYL9)
EGZ: 104125492(MYL9)
NNI: 104019952(MYL9)
ACUN: 113490665(MYL9)
PADL: 103921386(MYL9)
AAM: 106499912(MYL9)
ASN: 102381896(MYL9)
AMJ: 102575766(MYL9)
PSS: 102445169(MYL9)
CMY: 102934098
CPIC: 101946943(MYL9)
ACS: 100567783(myl9)
PVT: 110083027(MYL9)
PBI: 103055069(MYL9)
PMUR: 107288381(MYL9)
TSR: 106538627
PMUA: 114599524(MYL9)
GJA: 107112280(MYL9)
XLA: 446851(myl9.L) 447704
XTR: 100124811(myl9)
NPR: 108787984(MYL9)
DRE: 406493(myl9b) 450006(myl9a)
IPU: 100528638(myl9) 108276062
TRU: 101062217
LCO: 104936390
NCC: 104959430
MZE: 101473299
ONL: 100697131
OLA: 101167032
XMA: 102224997
XCO: 114135165
PRET: 103464948
CVG: 107102948
NFU: 107385525
KMR: 108239884
ALIM: 106518373
AOCE: 111565883
CSEM: 103386121
POV: 109629318
LCF: 108884031
SDU: 111221962
SLAL: 111667752
HCQ: 109522526
BPEC: 110165714
MALB: 109956204
SASA: 106565219(MLRN) 106583599(MLRN)
ELS: 105016743
PKI: 111856417
LCM: 102365825(MYL9)
CMK: 103171965(myl9)
RTP: 109933200
BFO: 118409548
SPU: 115922931
ADF: 107347202
AMIL: 114966450
PDAM: 113670059
DGT: 114525748
 » show all
Reference
PMID:2526655
  Authors
Kumar CC, Mohan SR, Zavodny PJ, Narula SK, Leibowitz PJ
  Title
Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells.
  Journal
Biochemistry 28:4027-35 (1989)
DOI:10.1021/bi00435a059
  Sequence
[hsa:10398]
LinkDB

KEGG   ORTHOLOGY: K12756
Entry
K12756                      KO                                     

Name
MYL10
Definition
myosin regulatory light chain 10
Pathway
ko04510  Focal adhesion
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12756  MYL10; myosin regulatory light chain 10
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12756  MYL10; myosin regulatory light chain 10
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K12756  MYL10; myosin regulatory light chain 10
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12756  MYL10; myosin regulatory light chain 10
   05131 Shigellosis
    K12756  MYL10; myosin regulatory light chain 10
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12756  MYL10; myosin regulatory light chain 10
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12756  MYL10; myosin regulatory light chain 10
Genes
HSA: 93408(MYL10)
PTR: 472470(MYL10)
PPS: 100971729(MYL10)
PON: 100442785(MYL10)
NLE: 100606269(MYL10)
MCC: 106997584(MYL10)
MCF: 102132373(MYL10)
CSAB: 103246683(MYL10)
RRO: 104681195(MYL10)
RBB: 108518899(MYL10)
CJC: 100389000(MYL10)
SBQ: 101041880(MYL10)
MMU: 59310(Myl10)
MCAL: 110295174(Myl10)
MPAH: 110312973(Myl10)
RNO: 501831(Myl10)
MUN: 110557238(Myl10)
CGE: 100767841(Myl10)
NGI: 103733488(Myl10)
HGL: 101698311(Myl10)
CCAN: 109681576(Myl10)
OCU: 100341579(MYL10)
TUP: 102473176(MYL10)
CFA: 608177(MYL10)
VVP: 112935732(MYL10)
AML: 100480951(MYL10)
UMR: 103670201(MYL10)
UAH: 113268005(MYL10)
ORO: 101385187(MYL10)
ELK: 111146160
FCA: 101082365(MYL10)
PTG: 102969892(MYL10)
PPAD: 109250506(MYL10)
AJU: 106980727(MYL10)
BTA: 617357(MYL10)
BOM: 102270468(MYL10)
BIU: 109578171(MYL10)
BBUB: 102390579(MYL10)
CHX: 102177024(MYL10)
OAS: 101118074(MYL10)
SSC: 100519360(MYL10)
CFR: 102506727(MYL10)
CDK: 105092385(MYL10)
BACU: 103016078(MYL10)
LVE: 103089055(MYL10)
OOR: 101271012(MYL10)
DLE: 111182314(MYL10)
PCAD: 102973456(MYL10)
ECB: 100060444(MYL10)
EPZ: 103551717(MYL10)
EAI: 106839338(MYL10)
MYB: 102250776(MYL10)
MYD: 102754378(MYL10)
MNA: 107526566(MYL10)
HAI: 109385005(MYL10)
DRO: 112314752(MYL10)
PALE: 102880440(MYL10)
RAY: 107511757(MYL10)
MJV: 108404603(MYL10)
LAV: 100670066(MYL10)
TMU: 101348970
MDO: 100028046(MYL10)
PCW: 110221306(MYL10)
OAA: 100073541(MYL10)
GGA: 417506(MYL10)
MGP: 100539263(MYL10)
CJO: 107322704(MYL10)
NMEL: 110407950(MYL10)
APLA: 101803605
ACYG: 106041480(MYL10)
TGU: 100221365(MYL10)
LSR: 110482075(MYL10)
SCAN: 103820068(MYL10)
GFR: 102034903(MYL10)
FAB: 101816977(MYL10)
PHI: 102110780(MYL10)
PMAJ: 107213032(MYL10)
CCAE: 111937685(MYL10)
CCW: 104691114(MYL10)
ETL: 114056697(MYL10)
FPG: 101923421(MYL10)
FCH: 102058260(MYL10)
CLV: 102095132(MYL10)
EGZ: 104131902(MYL10)
NNI: 104016106(MYL10)
ACUN: 113487097(MYL10)
PADL: 103912916(MYL10)
AAM: 106497327(MYL10)
ASN: 102386379
AMJ: 102559708(MYL10)
PSS: 102456345(MYL10)
CMY: 102944581
CPIC: 101951103(MYL10)
ACS: 100561920(myl10)
PVT: 110085140(MYL10)
PBI: 103059539(MYL10)
PMUR: 107294827
PMUA: 114585755(MYL10)
GJA: 107107690(MYL10)
XTR: 100170437(myl10)
NPR: 108801753(MYL10)
DRE: 550569(myl10)
CCAR: 109096873(myl10) 109096875
IPU: 100528744(mlrb) 108276823
EEE: 113583039(myl2) 113592196
NFU: 107393500
KMR: 108234899
LCF: 108893358
SDU: 111234328
SLAL: 111659975
SASA: 100196805(mlrb) 106568026
SFM: 108922365
LCM: 102366316(MYL10)
CMK: 103188437(myl10)
RTP: 109915750
 » show all
Reference
PMID:1628631
  Authors
Oltz EM, Yancopoulos GD, Morrow MA, Rolink A, Lee G, Wong F, Kaplan K, Gillis S, Melchers F, Alt FW
  Title
A novel regulatory myosin light chain gene distinguishes pre-B cell subsets and is IL-7 inducible.
  Journal
EMBO J 11:2759-67 (1992)
DOI:10.1002/j.1460-2075.1992.tb05341.x
  Sequence
[hsa:93408] [mmu:59310]
LinkDB

KEGG   ORTHOLOGY: K12757
Entry
K12757                      KO                                     

Name
MYL12
Definition
myosin regulatory light chain 12
Pathway
ko04360  Axon guidance
ko04510  Focal adhesion
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12757  MYL12; myosin regulatory light chain 12
   04530 Tight junction
    K12757  MYL12; myosin regulatory light chain 12
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12757  MYL12; myosin regulatory light chain 12
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K12757  MYL12; myosin regulatory light chain 12
   04670 Leukocyte transendothelial migration
    K12757  MYL12; myosin regulatory light chain 12
  09158 Development and regeneration
   04360 Axon guidance
    K12757  MYL12; myosin regulatory light chain 12
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12757  MYL12; myosin regulatory light chain 12
   05131 Shigellosis
    K12757  MYL12; myosin regulatory light chain 12
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12757  MYL12; myosin regulatory light chain 12
   04147 Exosome
    K12757  MYL12; myosin regulatory light chain 12
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12757  MYL12; myosin regulatory light chain 12
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   K12757  MYL12; myosin regulatory light chain 12
Genes
HSA: 103910(MYL12B) 10627(MYL12A)
PTR: 455313(MYL12B) 455314(MYL12A) 471369
PPS: 100972981 100977910(MYL12B) 100978696(MYL12A)
GGO: 101126168(MYL12B) 101127500 109028042 115934314
PON: 100172271(MYL12A) 100432987 100450310
NLE: 100585479(MYL12B) 100586474(MYL12A)
MCC: 694957(MYL12B) 695077(MYL12A)
MCF: 101926125 102124550(MYL12A)
CSAB: 103222701(MYL12B) 103222703(MYL12A)
RRO: 104654121(MYL12A) 104654122(MYL12B)
RBB: 108533552 108533553(MYL12B)
CJC: 100386818 100409903(MYL12B) 100410505(MYL12B)
MMU: 67268(Myl12a) 67938(Myl12b)
MPAH: 110335458(Myl12b) 110335459
RNO: 501203(Myl12a) 50685(Myl12b)
HGL: 101697884(Myl12b)
CFA: 480193(MYL12B) 607207
UAH: 113253249
PTG: 102971233(MYL12B) 102971525
AJU: 106971575 106971576(MYL12B)
BTA: 531505(MYL12A) 614055(MYL12B)
BOM: 102268971(MYL12B) 102269444
CHX: 102174891 102175348(MYL12B)
OAS: 100270714(MRCL3) 101105123
SSC: 414399(MRLC2) 733637
BACU: 103010250 103010734(MYL12B)
LVE: 103088639 103089268(MYL12B)
DLE: 111162912 111162972(MYL12B)
MYB: 102257812(MYL12B) 102258119
MYD: 102752077(MYL12B) 102752364
TMU: 101349753
MDO: 100012236 100012278(MYL12B)
PCW: 110197071 110197087(MYL12B)
OAA: 100092114
GGA: 396284(MYL12A) 770011(MYL12B)
CJO: 107310048
APLA: 101795371
ACYG: 106034947 106034948(MYL12B)
LSR: 110467854(MYL12B) 110467855
GFR: 102038378(MYL12B)
CCAE: 111923992
CCW: 104687298
ETL: 114058741(MYL12B)
FPG: 101921847(MYL12B) 101922135
CLV: 102098580(MYL12B) 102098877
AMJ: 102560494 102569016(MYL12A)
CMY: 102937279(MYL12B) 102938771
CPIC: 101935947(MYL12B) 101936202
ACS: 100565496
PVT: 110079422
PBI: 103060959
PMUR: 107294002
TSR: 106544631
PMUA: 114600714
GJA: 107118014
XLA: 108695600 380472(myl12b.L)
XTR: 448060(myl12b)
NPR: 108784895
DRE: 326719(myl12.1) 337084(myl12.2)
SASA: 106578694(MLRN) 106590146(MLRN)
LCM: 102346545
CMK: 103183460
RTP: 109927812
DME: Dmel_CG3595(sqh)
DSI: Dsimw501_GD16204(Dsim_sqh)
DYA: Dyak_GE16476(Dyak_sqh) Dyak_GE26184
DVI: 6629928
AALB: 109422051
AME: 550973
BIM: 100745561
BTER: 100644439
CCAL: 108629618
OBB: 114878150
MPHA: 105833233
AEC: 105144770
ACEP: 105621380
PBAR: 105422709
HST: 105186929
DQU: 106749045
CFO: 105255616
LHU: 105672816
PGC: 109853960
OBO: 105274559
NVI: 100115576
CSOL: 105362275
MDL: 103577593
TCA: 658477
DPA: 109542237
ATD: 109604965
NVL: 108561709
PMAC: 106714529
PXY: 105388071
API: 100163913
DNX: 107164171
CLEC: 106664184
ZNE: 110835883
FCD: 110858569
CEL: CELE_C36E6.3(mlc-1) CELE_C36E6.5(mlc-2) CELE_C56G7.1(mlc-4)
CBR: CBG01858(Cbr-mlc-2.2) CBG01859(Cbr-mlc-1) CBG09860(Cbr-mlc-4)
NVE: 5507361
HMG: 100204484
AQU: 100631435
CNE: CNE03510
CNB: CNBE3520
TASA: A1Q1_04366
MRR: Moror_408
ABP: AGABI1DRAFT67432(AGABI1DRAFT_67432)
ABV: AGABI2DRAFT196727(AGABI2DRAFT_196727)
MGL: MGL_3227
MRT: MRET_2467
 » show all
Reference
  Authors
Park I, Han C, Jin S, Lee B, Choi H, Kwon JT, Kim D, Kim J, Lifirsu E, Park WJ, Park ZY, Kim do H, Cho C
  Title
Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.
  Journal
Biochem J 434:171-80 (2011)
DOI:10.1042/BJ20101473
Reference
  Authors
Suizu F, Ueda K, Iwasaki T, Murata-Hori M, Hosoya H
  Title
Activation of actin-activated MgATPase activity of myosin II by phosphorylation with MAPK-activated protein kinase-1b (RSK-2).
  Journal
J Biochem 128:435-40 (2000)
DOI:10.1093/oxfordjournals.jbchem.a022771
Reference
  Authors
Iwasaki T, Murata-Hori M, Ishitobi S, Hosoya H
  Title
Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells.
  Journal
Cell Struct Funct 26:677-83 (2001)
DOI:10.1247/csf.26.677
  Sequence
LinkDB

KEGG   ORTHOLOGY: K12758
Entry
K12758                      KO                                     

Name
MYLPF
Definition
fast skeletal myosin light chain 2
Pathway
ko04510  Focal adhesion
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12758  MYLPF; fast skeletal myosin light chain 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K12758  MYLPF; fast skeletal myosin light chain 2
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K12758  MYLPF; fast skeletal myosin light chain 2
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12758  MYLPF; fast skeletal myosin light chain 2
   05131 Shigellosis
    K12758  MYLPF; fast skeletal myosin light chain 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12758  MYLPF; fast skeletal myosin light chain 2
   04147 Exosome
    K12758  MYLPF; fast skeletal myosin light chain 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12758  MYLPF; fast skeletal myosin light chain 2
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   K12758  MYLPF; fast skeletal myosin light chain 2
Genes
HSA: 29895(MYLPF)
PTR: 107968677(MYLPF)
PPS: 100979524(MYLPF)
GGO: 101154067(MYLPF)
PON: 100449813(MYLPF)
NLE: 100583586(MYLPF)
MCC: 711778(MYLPF)
MCF: 102115749(MYLPF)
CSAB: 103230879(MYLPF)
RRO: 104681544(MYLPF)
RBB: 108535399(MYLPF)
CJC: 100389704(MYLPF)
SBQ: 101053331(MYLPF)
MMU: 17907(Mylpf)
MCAL: 110297590(Mylpf)
MPAH: 110325851(Mylpf)
RNO: 24584(Mylpf)
MUN: 110548007(Mylpf)
CGE: 100772226(Mylpf)
NGI: 103726360(Mylpf)
HGL: 101721643(Mylpf)
CCAN: 109683076(Mylpf)
OCU: 100009542(MYLPF)
TUP: 102471535(MYLPF)
CFA: 479772(MYLPF)
VVP: 112929344(MYLPF)
AML: 100480191(MYLPF)
UMR: 103657856(MYLPF)
UAH: 113267993(MYLPF)
ORO: 101368899(MYLPF)
ELK: 111162187
FCA: 101094812(MYLPF)
PTG: 102950335(MYLPF)
PPAD: 109258960 109258998(MYLPF)
AJU: 106968964(MYLPF)
BTA: 514106(MYLPF)
BOM: 102283826(MYLPF)
BIU: 109578361(MYLPF)
BBUB: 102415315(MYLPF)
CHX: 100861163(MYLPF)
OAS: 100270715(MYLPF)
SSC: 474162(MYLPF)
CFR: 102520437(MYLPF)
CDK: 105102741(MYLPF)
BACU: 103014299
LVE: 103088449
OOR: 101277255(MYLPF)
DLE: 111181867(MYLPF)
PCAD: 102996446(MYLPF)
ECB: 100065683(MYLPF)
EPZ: 103547213(MYLPF)
EAI: 106831924(MYLPF)
MYB: 102242829(MYLPF)
MYD: 102770603(MYLPF)
MNA: 107541481(MYLPF)
HAI: 109374175(MYLPF)
DRO: 112304819(MYLPF)
PALE: 102898508(MYLPF)
RAY: 107515867(MYLPF)
MJV: 108404503(MYLPF)
TMU: 101348975
MDO: 100017537(MYLPF)
SHR: 100927147(MYLPF)
PCW: 110223139(MYLPF)
OAA: 100088546(MYLPF)
GGA: 776775(MYLPF)
PHI: 102107090
ASN: 102371005
AMJ: 106739007
PSS: 102457840
CMY: 102946735(MYLPF)
CPIC: 101934099(MYLPF)
ACS: 100559161(mylpf)
PVT: 110090087(MYLPF)
PBI: 103065656(MYLPF)
TSR: 106548962(MYLPF)
PMUA: 114582017(MYLPF)
GJA: 107106266(MYLPF)
XLA: 108701718 399251(mylpf.L)
XTR: 394763(mylpf)
NPR: 108803796
DRE: 30429(mylpfa) 447930(mylpfb)
IPU: 100528939(mylpf) 108274226
TRU: 101065126(mylpf) 101068214
LCO: 104926897 104930230(mylpf)
NCC: 104943733(mylpf) 104946777
ONL: 100702521(mylpf) 100709026
OLA: 100049525(mylpf) 101169321
PRET: 103468934(mylpf) 103481362
CVG: 107084822(mylpf) 107085585
ALIM: 106529524 106533791(mylpf)
AOCE: 111577733 111587863(mylpf)
CSEM: 103381607 103392671(mylpf)
POV: 109634336(mylpf) 109642811
LCF: 108880619(mylpf) 108890423
SDU: 111217468(mylpf) 111219734
MALB: 109963154(mylpf) 109973608
SASA: 100137048(mlc-2) 106580483 106606900(mlc-2)
ELS: 105012967(mylpf) 105030207
LCM: 102348776(MYLPF)
 » show all
Reference
  Authors
Sachdev S, Raychowdhury MK, Sarkar S
  Title
Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships.
  Journal
DNA Seq 14:339-50 (2003)
DOI:10.1080/1042517031000154952
  Sequence
[hsa:29895]
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