KEGG   ORTHOLOGY: K10928
Entry
K10928                      KO                                     

Name
ctxA
Definition
cholera enterotoxin subunit A [EC:2.4.2.36]
Pathway
ko05110  Vibrio cholerae infection
ko05111  Biofilm formation - Vibrio cholerae
Module
M00576  ETEC pathogenicity signature, heat-labile and heat-stable enterotoxins
M00850  Vibrio cholerae pathogenicity signature, cholera toxins
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   05111 Biofilm formation - Vibrio cholerae
    K10928  ctxA; cholera enterotoxin subunit A
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K10928  ctxA; cholera enterotoxin subunit A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K10928  ctxA; cholera enterotoxin subunit A
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.36  NAD+---diphthamide ADP-ribosyltransferase
     K10928  ctxA; cholera enterotoxin subunit A
Bacterial toxins [BR:ko02042]
 Type III toxins: Intracellular toxins
  ADP-ribosyltransferase
   Cholera toxin/Heat-labile enterotoxin
    K10928  ctxA; cholera enterotoxin subunit A
Other DBs
GO: 0047286
Genes
ELH: ETEC_p666_0660(eltA)
ECW: EcE24377A_F0020(eltA)
EUN: UMNK88_pEnt35(eltA)
ESZ: FEM44_21945
VCH: VC1457
VCF: IR04_12525
VCS: MS6_1231 MS6_1242
VCE: Vch1786_I0953(ctxA)
VCQ: EN18_10490
VCJ: VCD_000750
VCI: O3Y_06775
VCO: VC0395_0512(ctxA) VC0395_A1060(ctxA)
VCR: VC395_1571(ctxA) VC395_A0747(ctxA)
VG: 10271077(ctxA)
 » show all
Reference
PMID:791600
  Authors
Van Heyningen WE, Van Heyningen S, King CA
  Title
The nature and action of cholera toxin.
  Journal
Ciba Found Symp 73-88 (1976)
DOI:10.1002/9780470720240.ch5
Reference
  Authors
Syed KA, Beyhan S, Correa N, Queen J, Liu J, Peng F, Satchell KJ, Yildiz F, Klose KE
  Title
The Vibrio cholerae flagellar regulatory hierarchy controls expression of virulence factors.
  Journal
J Bacteriol 191:6555-70 (2009)
DOI:10.1128/JB.00949-09
  Sequence
[vch:VC1457]
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