KEGG   ORTHOLOGY: K10956
Entry
K10956                      KO                                     

Name
SEC61A
Definition
protein transport protein SEC61 subunit alpha
Pathway
ko03060  Protein export
ko04141  Protein processing in endoplasmic reticulum
ko04145  Phagosome
ko05110  Vibrio cholerae infection
Disease
H00541  Autosomal dominant tubulointerstitial kidney disease
H02011  Familial juvenile hyperuricemic nephropathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
   04141 Protein processing in endoplasmic reticulum
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
Secretion system [BR:ko02044]
 Sec (secretion) system
  Eukaryotic Sec-SRP protein
   K10956  SEC61A; protein transport protein SEC61 subunit alpha
Other DBs
TC: 3.A.5.4 3.A.5.8 3.A.5.9
Genes
HSA: 29927(SEC61A1) 55176(SEC61A2)
PTR: 450305(SEC61A2) 460669(SEC61A1)
PPS: 100979100(SEC61A2) 100979567(SEC61A1)
GGO: 101145654(SEC61A1) 101147036(SEC61A2)
PON: 100173741(SEC61A1) 100174115(SEC61A2)
NLE: 100599187(SEC61A2) 100603743(SEC61A1)
MCC: 100427731(SEC61A2) 709787(SEC61A1)
MCF: 102116756(SEC61A1) 102119298(SEC61A2)
CSAB: 103228100(SEC61A1) 103237891
RRO: 104656940(SEC61A1) 104664883(SEC61A2)
RBB: 108519219 108537478(SEC61A1) 108538528(SEC61A2)
CJC: 100413259(SEC61A1) 100415365(SEC61A2)
SBQ: 101038739(SEC61A1) 101041434(SEC61A2)
MMU: 53421(Sec61a1) 57743(Sec61a2)
MCAL: 110295994(Sec61a1) 110311759(Sec61a2)
MPAH: 110315724(Sec61a1) 110333596(Sec61a2)
RNO: 361273(Sec61a2) 80843(Sec61a1)
CGE: 100767375(Sec61a1) 100771837(Sec61a2)
NGI: 103730347(Sec61a1) 103738699(Sec61a2)
HGL: 101711449(Sec61a1) 101724032(Sec61a2)
CCAN: 109682444(Sec61a2) 109684702(Sec61a1)
OCU: 100338258(SEC61A2) 100338900(SEC61A1)
TUP: 102480124(SEC61A2) 102490355(SEC61A1)
CFA: 404006(SEC61A1) 478007(SEC61A2)
VVP: 112914480(SEC61A1) 112933357(SEC61A2)
AML: 100478647(SEC61A1) 100484123(SEC61A2)
UMR: 103669615(SEC61A1) 103676291(SEC61A2)
UAH: 113241066(SEC61A2) 113257265(SEC61A1)
ORO: 101363735(SEC61A2) 101365069(SEC61A1)
FCA: 101086402(SEC61A2) 101089426(SEC61A1)
PTG: 102955516(SEC61A2) 102966531(SEC61A1)
PPAD: 109256060(SEC61A1) 109273727(SEC61A2)
AJU: 106971003(SEC61A2) 106986127(SEC61A1)
BTA: 505064(SEC61A1) 614128(SEC61A2)
BOM: 102264991(SEC61A1) 102283876(SEC61A2)
BIU: 109567871(SEC61A2) 109576222(SEC61A1)
BBUB: 102389095(SEC61A1) 102412467(SEC61A2)
CHX: 102173946(SEC61A2) 102175814(SEC61A1)
OAS: 101108676(SEC61A2) 101114060(SEC61A1)
SSC: 100155306(SEC61A1) 100511831(SEC61A2)
CFR: 102505665(SEC61A2) 102523145(SEC61A1)
CDK: 105090114(SEC61A1) 105100311(SEC61A2)
BACU: 103012399(SEC61A1) 103015508(SEC61A2)
LVE: 103079854 103086204(SEC61A1) 103088812(SEC61A2)
OOR: 101271372(SEC61A2) 101275317 101281798 101284382(SEC61A1)
DLE: 111168794(SEC61A1) 111178002(SEC61A2)
PCAD: 102978958(SEC61A1) 102987023(SEC61A2) 102996121 112063169
ECB: 100054080(SEC61A1) 100069336(SEC61A2)
EPZ: 103558629(SEC61A1) 103563360(SEC61A2)
EAI: 106834472(SEC61A1) 106836525(SEC61A2)
MYB: 102243493(SEC61A2) 102253190(SEC61A1)
MYD: 102755050(SEC61A2) 102770957(SEC61A1)
MNA: 107525213(SEC61A1) 107530245(SEC61A2)
HAI: 109390484(SEC61A2) 109391269(SEC61A1)
DRO: 112322639(SEC61A2) 112322883(SEC61A1)
PALE: 102895305(SEC61A2) 102896092(SEC61A1)
RAY: 107503655(SEC61A1) 107504854(SEC61A2)
MJV: 108394206(SEC61A1) 108395810(SEC61A2)
LAV: 100653932(SEC61A2) 100672139(SEC61A1)
MDO: 100013623(SEC61A2) 100027900(SEC61A1)
SHR: 100926239(SEC61A2) 100927239(SEC61A1)
PCW: 110204938(SEC61A1) 110217362(SEC61A2)
OAA: 100075168(SEC61A1) 100085428(SEC61A2)
GGA: 416023(SEC61A1) 426369(SEC61A2)
MGP: 100538490(SEC61A1) 100540625(SEC61A2)
CJO: 107317364(SEC61A2) 107319981(SEC61A1)
NMEL: 110392261(SEC61A2) 110404854(SEC61A1)
APLA: 101793156(SEC61A2) 101805438(SEC61A1)
ACYG: 106038064(SEC61A1) 106046212(SEC61A2)
TGU: 100230635(SEC61A2) 100232642(SEC61A1)
LSR: 110470927(SEC61A2) 110471485(SEC61A1)
SCAN: 103813571(SEC61A2) 103817022(SEC61A1)
GFR: 102043686(SEC61A1) 102045195(SEC61A2)
FAB: 101810680(SEC61A1) 101819921(SEC61A2)
PHI: 102101105(SEC61A2) 102110505(SEC61A1)
PMAJ: 107204634(SEC61A2) 107210406(SEC61A1)
CCAE: 111923120(SEC61A2) 111935079(SEC61A1)
CCW: 104683473(SEC61A1) 104694503(SEC61A2)
ETL: 114057950(SEC61A1) 114066634(SEC61A2)
FPG: 101912538(SEC61A1) 101914707(SEC61A2)
FCH: 102046030(SEC61A2) 102057607(SEC61A1)
CLV: 102086241(SEC61A2) 102093863(SEC61A1)
EGZ: 104126631(SEC61A1) 104135762(SEC61A2)
NNI: 104014623(SEC61A2) 104022671(SEC61A1)
ACUN: 113484941(SEC61A1) 113491257(SEC61A2)
PADL: 103914411(SEC61A1) 103915025(SEC61A2)
AAM: 106485094(SEC61A2) 106500278(SEC61A1)
ASN: 102373630(SEC61A2) 102381045(SEC61A1)
AMJ: 102561868(SEC61A2) 106736938(SEC61A1)
PSS: 102458682(SEC61A1) 102460252(SEC61A2)
CMY: 102941548(SEC61A2) 102943934(SEC61A1)
CPIC: 101938621(SEC61A1) 101939960(SEC61A2)
ACS: 100567770(sec61a1)
PVT: 110081240(SEC61A2) 110088891(SEC61A1)
PBI: 103048227(SEC61A1) 103065081(SEC61A2)
PMUR: 107294279(SEC61A1) 107297193(SEC61A2)
TSR: 106547009(SEC61A1) 106550931(SEC61A2)
PMUA: 114591735(SEC61A1) 114605173(SEC61A2)
GJA: 107122943(SEC61A1)
XLA: 108714662(sec61a1.L) 379936(sec61a1.S)
XTR: 448033(sec61a1)
NPR: 108784976(SEC61A1)
DRE: 192298(sec61a1) 266796(sec61a1l)
CCAR: 109067675 109091081(sec61a1) 109091101
EEE: 113575977
TRU: 101061140(sec61a1) 101075256
ONL: 100696698 100703518(sec61a1)
OLA: 101169601 101175640(sec61a1)
CVG: 107094024(sec61a1) 107100419
KMR: 108235565 108241220(sec61a1)
CSEM: 103386165(sec61a1)
SDU: 111221564 111221582(sec61a1)
MALB: 109956207(sec61a1) 109964524
SASA: 100195187(s61a1) 100380825(sc61a) 106565561 106583199
LCM: 102358133(SEC61A1) 102359033(SEC61A2)
CMK: 103176668(sec61a1) 103187913(sec61a2)
RTP: 109921354 109929694(sec61a2)
BFO: 118415685
CIN: 100176997
APLC: 110987733
SKO: 100377121
DME: Dmel_CG9539(Sec61alpha)
DER: 6540948
DSE: 6613632
DSI: Dsimw501_GD22572(Dsim_GD22572)
DAN: 6498511
DSR: 110185078
DPE: 6593558
DMN: 108163319
DWI: 6646717
DAZ: 108611238
DNV: 115563309
DHE: 111596273
DVI: 6634213
MDE: 101890594
LCQ: 111674554
AME: 725571
BIM: 100747066
BTER: 100644740
CCAL: 108622582
OBB: 114876651
SOC: 105207861
MPHA: 105830263
AEC: 105154433
ACEP: 105621039
PBAR: 105428379
VEM: 105569478
HST: 105191762
DQU: 106752377
CFO: 105252208
LHU: 105669772
PGC: 109856141
OBO: 105276638
PCF: 106789016
MDL: 103571226
TCA: 658693
DPA: 109545449
ATD: 109597194
NVL: 108569651
BMOR: 733068(Sec61alpha)
BMAN: 114239861
PMAC: 106721338
PRAP: 110993494
HAW: 110383255
TNL: 113502385
API: 100144911(Sec61a1)
DNX: 107173078
AGS: 114123616
RMD: 113551304
BTAB: 109032299
CLEC: 106672125
ZNE: 110836545
FCD: 110846340
TUT: 107364556
CSCU: 111631285
PTEP: 107439636
CEL: CELE_Y57G11C.15(sec-61.A)
BMY: Bm1_38585
PCAN: 112571999
MYI: 110445924
OBI: 106872762
SHX: MS3_03569
NVE: 5507445
EPA: 110240522
ADF: 107337419
AMIL: 114963929
PDAM: 113667419
SPIS: 111338785
DGT: 114527080
HMG: 100200475
AQU: 100635757
LJA: Lj4g3v0880270.1(Lj4g3v0880270.1) Lj6g3v1049120.1(Lj6g3v1049120.1) Lj6g3v1049120.2(Lj6g3v1049120.2)
DOSA: Os03t0213100-01(Os03g0213100) Os03t0692300-00(Os03g0692300) Os08t0254500-01(Os08g0254500) Os09t0347500-01(Os09g0347500) Os09t0347700-01(Os09g0347700) Os09t0512000-01(Os09g0512000)
ATS: 109731640(LOC109731640) 109741620(LOC109741620) 109764831(LOC109764831) 109770287(LOC109770287)
ZMA: 100217058 100276798 100280289(pco109407) 542482(csy1)
CRE: CHLREDRAFT_188207(SEC61A)
MIS: MICPUN_95488(SEC61a)
SCE: YBR283C(SSH1) YLR378C(SEC61)
KMX: KLMA_20424(SEC61) KLMA_50087(SSH1)
NCS: NCAS_0B07560(NCAS0B07560) NCAS_0J01340(NCAS0J01340)
NDI: NDAI_0B04900(NDAI0B04900) NDAI_0J02130(NDAI0J02130)
TPF: TPHA_0B02340(TPHA0B02340) TPHA_0I01160(TPHA0I01160)
TBL: TBLA_0C02600(TBLA0C02600) TBLA_0I02820(TBLA0I02820)
TDL: TDEL_0D01700(TDEL0D01700) TDEL_0E01420(TDEL0E01420)
KAF: KAFR_0A03640(KAFR0A03640) KAFR_0A06090(KAFR0A06090)
PIC: PICST_68832(SEC61) PICST_80530(SSH1)
SLB: AWJ20_1740(SEC61) AWJ20_2263(SEC61)
NCR: NCU08897
NTE: NEUTE1DRAFT116142(NEUTE1DRAFT_116142)
MGR: MGG_04856
SSCK: SPSK_06140
MAW: MAC_07314
MAJ: MAA_09744
CMT: CCM_09589
MBE: MBM_08204
ANI: AN7721.2
ANG: ANI_1_512034(An03g04340)
ABE: ARB_06748
TVE: TRV_03333
PTE: PTT_09674
CNE: CNI00040
CNB: CNBH0050
TASA: A1Q1_02607
MRR: Moror_6
ABP: AGABI1DRAFT114587(AGABI1DRAFT_114587)
ABV: AGABI2DRAFT194769(AGABI2DRAFT_194769)
MGL: MGL_1638
MRT: MRET_0735
DDI: DDB_G0278885(sec61a)
DFA: DFA_08267(sec61a)
EHI: EHI_164500(467.t00007)
PCB: PCHAS_136360(PC302415.00.0)
TAN: TA17425
TPV: TP03_0852
BBO: BBOV_I000080(16.m00785)
CPV: cgd7_950
SMIN: v1.2.009289.t1(symbB.v1.2.009289.t1) v1.2.009606.t1(symbB.v1.2.009606.t1)
PTI: PHATRDRAFT_56443(Sec61alpha)
TPS: THAPSDRAFT_28769(SEC61-2) THAPS_25355(SEC61-1)
NGA: Ngar_c02020(secY)
NVN: NVIE_013880(secY)
NEV: NTE_02794
BARC: AOA65_0151
BARB: AOA66_1261
LOKI: Lokiarch_00020(secY)
 » show all
Reference
  Authors
Rapoport TA
  Title
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
  Journal
Nature 450:663-9 (2007)
DOI:10.1038/nature06384
Reference
  Authors
Jiang Y, Cheng Z, Mandon EC, Gilmore R
  Title
An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation.
  Journal
J Cell Biol 180:1149-61 (2008)
DOI:10.1083/jcb.200707196
  Sequence
Reference
  Authors
Lang S, Erdmann F, Jung M, Wagner R, Cavalie A, Zimmermann R
  Title
Sec61 complexes form ubiquitous ER Ca2+ leak channels.
  Journal
Channels (Austin) 5:228-35 (2011)
DOI:10.4161/chan.5.3.15314
  Sequence
[hsa:29927]
LinkDB

KEGG   ORTHOLOGY: K09481
Entry
K09481                      KO                                     

Name
SEC61B, SBH2
Definition
protein transport protein SEC61 subunit beta
Pathway
ko03060  Protein export
ko04141  Protein processing in endoplasmic reticulum
ko04145  Phagosome
ko05110  Vibrio cholerae infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
   04141 Protein processing in endoplasmic reticulum
    K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
Secretion system [BR:ko02044]
 Sec (secretion) system
  Eukaryotic Sec-SRP protein
   K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
Other DBs
TC: 3.A.5.4 3.A.5.8 3.A.5.9
Genes
HSA: 10952(SEC61B)
PTR: 747589(SEC61B)
PPS: 100985118(SEC61B)
GGO: 101129212(SEC61B)
PON: 100190850(SEC61B)
NLE: 100593538(SEC61B)
MCC: 717815(SEC61B)
MCF: 102114907(SEC61B)
CSAB: 103219137(SEC61B)
RRO: 104657763(SEC61B)
RBB: 108512463(SEC61B)
CJC: 100413011(SEC61B)
SBQ: 101031213(SEC61B)
MMU: 66212(Sec61b)
MCAL: 110293129(Sec61b)
MPAH: 110323530(Sec61b)
RNO: 298068(Sec61b)
CGE: 100768703(Sec61b)
NGI: 103749081(Sec61b)
HGL: 101717405(Sec61b)
CCAN: 109691421(Sec61b)
OCU: 100352882(SEC61B)
TUP: 102477656(SEC61B)
CFA: 404018(SEC61B)
VVP: 112930772(SEC61B)
AML: 100471006(SEC61B)
UMR: 103678507(SEC61B)
UAH: 113260404(SEC61B)
ORO: 101380040(SEC61B)
ELK: 111146146
FCA: 101084323(SEC61B)
PTG: 102949726(SEC61B)
PPAD: 109270078(SEC61B)
AJU: 106972057(SEC61B)
BTA: 506986(SEC61B)
BOM: 102282274(SEC61B)
BIU: 109563081(SEC61B)
BBUB: 102396501(SEC61B)
CHX: 102173297(SEC61B)
OAS: 101102793(SEC61B)
SSC: 100511362(SEC61B)
CFR: 102522234(SEC61B)
CDK: 105086889(SEC61B)
BACU: 103000171(SEC61B) 103010151
LVE: 103071399(SEC61B)
OOR: 101288059(SEC61B)
DLE: 111188085(SEC61B)
PCAD: 102982464(SEC61B)
ECB: 100630021(SEC61B)
EPZ: 103555264(SEC61B)
EAI: 106842923(SEC61B)
MYB: 102257820(SEC61B)
MYD: 102768801(SEC61B)
MNA: 107545034(SEC61B)
HAI: 109386429(SEC61B)
DRO: 112304451(SEC61B)
PALE: 102880251(SEC61B)
RAY: 107500591(SEC61B)
MJV: 108394150(SEC61B)
LAV: 100655717(SEC61B)
TMU: 101352252
MDO: 100011332(SEC61B)
SHR: 100932683(SEC61B)
PCW: 110214539(SEC61B)
OAA: 114807664(SEC61B)
GGA: 420997(SEC61B)
MGP: 100538573(SEC61B)
CJO: 107309971(SEC61B)
NMEL: 110393669(SEC61B)
APLA: 101794894(SEC61B)
ACYG: 106036024(SEC61B)
TGU: 100190240(SEC61B)
LSR: 110469689(SEC61B)
SCAN: 103815688(SEC61B)
PHI: 102103353(SEC61B)
PMAJ: 107200760(SEC61B)
CCAE: 111925310(SEC61B)
ETL: 114058962(SEC61B)
FPG: 101912518(SEC61B)
FCH: 102057840(SEC61B)
CLV: 102094492(SEC61B)
EGZ: 104130456(SEC61B)
NNI: 104018203(SEC61B)
PADL: 103917757(SEC61B)
AAM: 106496978(SEC61B)
ASN: 102385013(SEC61B)
AMJ: 102564629(SEC61B)
PSS: 102448292(SEC61B)
CPIC: 101942913(SEC61B)
ACS: 100552074(sec61b)
PVT: 110086079(SEC61B)
PBI: 103051142(SEC61B)
PMUR: 107291672(SEC61B)
TSR: 106538369(SEC61B)
PMUA: 114582037(SEC61B)
XLA: 379848(sec61b.L)
XTR: 100038128(sec61b)
NPR: 108797277(SEC61B)
DRE: 791986(sec61b)
CCAR: 109105977 109106006(sec61b)
IPU: 108256666(sec61b)
PHYP: 113532963(sec61b)
AMEX: 103028456(sec61b)
EEE: 113590841(sec61b)
TRU: 101076269(sec61b)
LCO: 104923021(sec61b)
NCC: 104966075(sec61b)
MZE: 101485223(sec61b)
ONL: 100704710(sec61b)
OLA: 101167479(sec61b)
XMA: 102221758(sec61b)
XCO: 114141941(sec61b)
PRET: 103478648(sec61b)
CVG: 107101088(sec61b)
NFU: 107379757(sec61b)
KMR: 108241121(sec61b)
ALIM: 106527091(sec61b)
AOCE: 111577877(sec61b)
CSEM: 103388136(sec61b)
POV: 109633442(sec61b)
LCF: 108889642(sec61b)
SDU: 111236922(sec61b)
SLAL: 111650854(sec61b)
HCQ: 109515464(sec61b)
BPEC: 110171691(sec61b)
MALB: 109964159(sec61b)
SASA: 100196587(sc61b) 106574520
SALP: 112079888(sec61b)
ELS: 105018905(sec61b)
SFM: 108940605(sec61b)
PKI: 111845873(sec61b)
CMK: 103181172(sec61b)
RTP: 109911405(sec61b)
BFO: 118405828
CIN: 100175466
APLC: 110990817
SKO: 100368184
DME: Dmel_CG10130(Sec61beta)
DER: 6549391
DSE: 6609169
DSI: Dsimw501_GD11064(Dsim_GD11064)
DYA: Dyak_GE13599(Dyak_Sec61beta)
DAN: 6494199
DSR: 110190920
DPE: 6590941
DWI: 6639854
DAZ: 108616709
DNV: 115564993
DHE: 111597119
DVI: 6625278
MDE: 101887354
LCQ: 111686109
AAG: 5579041
AME: 724188
BIM: 100745883
BTER: 100645405
CCAL: 108625267
OBB: 114873217
SOC: 105195581
MPHA: 105835158
AEC: 105144569
ACEP: 105618439
PBAR: 105431680
VEM: 105569744
HST: 105184391
DQU: 106746190
CFO: 105258350
LHU: 105673852
PGC: 109857216
OBO: 105278323
PCF: 106791484
NVI: 100113628
CSOL: 105361183
MDL: 103578869
TCA: 663663
DPA: 109537281
NVL: 108568310
BMOR: 733070
BMAN: 114250962
PMAC: 106710770
PRAP: 110998641
HAW: 110375486
API: 100160371
DNX: 107170995
AGS: 114125027
RMD: 113557086
BTAB: 109029702
ZNE: 110828172
FCD: 110863308
PVM: 113809401
TUT: 107363216
CSCU: 111624302
PTEP: 107450216
CEL: CELE_Y38F2AR.9(sec-61.B)
CBR: CBG16816
BMY: Bm1_29310
TSP: Tsp_08090
PCAN: 112574229
CRG: 105346081
MYI: 110442031
OBI: 106872596
LAK: 106164352
SHX: MS3_08490
EGL: EGR_07155
EPA: 110234753
ADF: 107331102
AMIL: 114977875
PDAM: 113676061
SPIS: 111325692
DGT: 114525706
HMG: 100205562
AQU: 100631872
ATH: AT2G45070(SEC61_BETA) AT3G60540 AT5G60460
LJA: Lj0g3v0131319.1(Lj0g3v0131319.1) Lj0g3v0149239.1(Lj0g3v0149239.1)
BVG: 104905336
SOE: 110788996
DOSA: Os01t0565900-01(Os01g0565900) Os11t0104050-01(Os11g0104050) Os12t0103300-01(Os12g0103300) Os12t0173366-01(Os12g0173366)
OBR: 102720103
ATS: 109731464(LOC109731464) 109747555(LOC109747555) 109748165(LOC109748165) 109767819 109778801(LOC109778801)
CRE: CHLREDRAFT_1670(SEC61B)
VCN: VOLCADRAFT_76207(sec61B)
SCE: YER019C-A(SBH2) YER087C-B(SBH1)
ERC: Ecym_4706
KMX: KLMA_80337(SBH1)
NCS: NCAS_0A14260(NCAS0A14260) NCAS_0E02760(NCAS0E02760)
NDI: NDAI_0A01790(NDAI0A01790) NDAI_0E04720(NDAI0E04720)
TPF: TPHA_0E01040(TPHA0E01040) TPHA_0F03120(TPHA0F03120)
TBL: TBLA_0A07640(TBLA0A07640) TBLA_0C05090(TBLA0C05090)
TDL: TDEL_0C01780(TDEL0C01780)
KAF: KAFR_0K01710(KAFR0K01710)
NCR: NCU08379
NTE: NEUTE1DRAFT90703(NEUTE1DRAFT_90703)
MGR: MGG_03644
SSCK: SPSK_06670
MAJ: MAA_00538
CMT: CCM_00994
MBE: MBM_03555
ANI: AN0417.2
ANG: ANI_1_508014(An01g03820)
ABE: ARB_06137
TVE: TRV_03812
SPO: SPBC2G2.03c(sbh1)
CNE: CNN00800
CNB: CNBN0790
ABP: AGABI1DRAFT115034(AGABI1DRAFT_115034)
ABV: AGABI2DRAFT153873(AGABI2DRAFT_153873)
MGL: MGL_1886
MRT: MRET_1923
DDI: DDB_G0278117(sec61b)
DFA: DFA_10262(sec61b)
TAN: TA06240
TPV: TP01_0893
CPV: cgd2_620
SMIN: v1.2.011624.t1(symbB.v1.2.011624.t1) v1.2.033949.t1(symbB.v1.2.033949.t1)
SPAR: SPRG_21882
 » show all
Reference
  Authors
Rapoport TA
  Title
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
  Journal
Nature 450:663-9 (2007)
DOI:10.1038/nature06384
Reference
  Authors
Liao HJ, Carpenter G
  Title
Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression.
  Journal
Mol Biol Cell 18:1064-72 (2007)
DOI:10.1091/mbc.E06-09-0802
  Sequence
[hsa:10952]
LinkDB

KEGG   ORTHOLOGY: K07342
Entry
K07342                      KO                                     

Name
SEC61G, SSS1, secE
Definition
protein transport protein SEC61 subunit gamma and related proteins
Pathway
ko03060  Protein export
ko04141  Protein processing in endoplasmic reticulum
ko04145  Phagosome
ko05110  Vibrio cholerae infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
   04141 Protein processing in endoplasmic reticulum
    K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
Secretion system [BR:ko02044]
 Sec (secretion) system
  Eukaryotic Sec-SRP protein
   K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
Other DBs
COG: COG2443
TC: 3.A.5.7 3.A.5.8 3.A.5.9
Genes
HSA: 23480(SEC61G)
PTR: 387278(SEC61G)
PPS: 100974099(SEC61G)
GGO: 101124853(SEC61G)
PON: 100459650(SEC61G)
NLE: 100595891(SEC61G)
MCC: 716898(SEC61G)
MCF: 102140351(SEC61G)
CSAB: 103226057(SEC61G)
RRO: 104675888(SEC61G)
RBB: 108522042(SEC61G)
CJC: 100411550(SEC61G)
SBQ: 101046824(SEC61G)
MMU: 100046078(Gm15266) 102632470(Gm30534) 20335(Sec61g)
MPAH: 110325321 110330908(Sec61g)
RNO: 689134(Sec61g)
NGI: 103748851(Sec61g)
HGL: 101724375(Sec61g)
CCAN: 109702904(Sec61g)
OCU: 100346284(SEC61G)
TUP: 102480112(SEC61G)
CFA: 404017(SEC61G)
VVP: 112925822(SEC61G)
AML: 100483954(SEC61G)
UMR: 103674548(SEC61G)
UAH: 113257461(SEC61G)
ELK: 111157034
FCA: 101084431(SEC61G)
PTG: 102956906(SEC61G)
PPAD: 109267978(SEC61G)
AJU: 106976983(SEC61G)
BTA: 615778(SEC61G)
BOM: 102269051(SEC61G)
BIU: 109576437(SEC61G)
BBUB: 102397589(SEC61G) 102409896
CHX: 102171662(SEC61G)
SSC: 100517415(SEC61G)
CFR: 102524458(SEC61G)
BACU: 103016737(SEC61G)
LVE: 103071678(SEC61G)
OOR: 101275644(SEC61G)
DLE: 111184549(SEC61G)
PCAD: 102994182(SEC61G) 112065466
ECB: 100629979(SEC61G)
EPZ: 103543613(SEC61G)
EAI: 106829699(SEC61G)
MYB: 102259734(SEC61G)
MYD: 102763022(SEC61G)
MNA: 107525995(SEC61G)
HAI: 109388360(SEC61G)
DRO: 112306926(SEC61G)
PALE: 102879331 102897518(SEC61G)
RAY: 107501318(SEC61G) 107521435
MJV: 108400583(SEC61G)
LAV: 100658836(SEC61G)
MDO: 100018497(SEC61G)
SHR: 100935203(SEC61G)
PCW: 110204992(SEC61G)
OAA: 100075272(SEC61G)
GGA: 776639(SEC61G)
MGP: 100542792(SEC61G)
CJO: 107309808(SEC61G)
NMEL: 110394438(SEC61G)
APLA: 101791910(SEC61G)
ACYG: 106046414(SEC61G)
TGU: 100220928(SEC61G)
LSR: 110471173(SEC61G)
SCAN: 108962580(SEC61G)
GFR: 102038066(SEC61G)
FAB: 101811183(SEC61G)
PHI: 102101148(SEC61G)
PMAJ: 107200856(SEC61G)
CCAE: 111923653(SEC61G)
CCW: 104688920(SEC61G)
ETL: 114057238(SEC61G)
FPG: 101924776(SEC61G)
FCH: 102055218(SEC61G)
CLV: 102096803(SEC61G)
EGZ: 104131584(SEC61G)
ACUN: 113477560(SEC61G)
AAM: 106495286(SEC61G)
ASN: 102376864(SEC61G)
AMJ: 102561472(SEC61G)
PSS: 102444061(SEC61G)
CPIC: 101953386(SEC61G)
ACS: 107982990(sec61g)
PVT: 110090021(SEC61G)
PMUR: 107284698(SEC61G)
TSR: 106553783(SEC61G)
PMUA: 114607520(SEC61G)
GJA: 107110462(SEC61G)
XLA: 100329133(sec61g.S) 394424(sec61g.L)
XTR: 100492802(sec61g)
NPR: 108799484(SEC61G)
DRE: 436772(sec61g)
AMEX: 107197735(sec61g)
EEE: 113589252(sec61g)
TRU: 115251207(sec61g)
LCO: 104922587(sec61g)
NCC: 104957083(sec61g)
MZE: 101468554(sec61g)
ONL: 106098101(sec61g)
OLA: 110017315(sec61g)
XMA: 106699749(sec61g)
XCO: 114136807(sec61g)
PRET: 108165712(sec61g)
CVG: 107093952(sec61g)
NFU: 107382984(sec61g)
KMR: 108243169(sec61g)
ALIM: 106517554(sec61g)
AOCE: 111565917(sec61g)
CSEM: 107988395(sec61g)
POV: 109629666(sec61g)
LCF: 108900787(sec61g)
SDU: 111237256(sec61g)
SLAL: 111662920(sec61g)
HCQ: 109515573(sec61g)
BPEC: 110161010(sec61g)
MALB: 109963720(sec61g)
SASA: 100196855(sc61g) 106569220(SC61G) 106590555(SC61G)
SFM: 108935440(sec61g)
PKI: 111837166(sec61g)
LCM: 106703905(SEC61G)
CMK: 103187901(sec61g)
RTP: 109913151(sec61g)
BFO: 118403933
CIN: 445686(sec61g)
DME: Dmel_CG13426(CG13426) Dmel_CG14214(Sec61gamma) Dmel_CG8860(CG8860)
DSI: Dsimw501_GD15244(Dsim_GD15244) Dsimw501_GD25279(Dsim_GD25279) Dsimw501_GD27473(Dsim_GD27473)
DAN: 6503124
DAZ: 108618467
DVI: 6634545
MDE: 101893770
LCQ: 111687621
AAG: 5566551
AALB: 109433502
AME: 726721
BIM: 100745641
BTER: 100644410
CCAL: 108626698
OBB: 114873015
SOC: 105197298
MPHA: 105830402
AEC: 105145535
ACEP: 105626390
PBAR: 105423052
VEM: 105559036
HST: 105190519
DQU: 106748319
CFO: 109610343
LHU: 105667843
PGC: 109855045
OBO: 105287162
PCF: 106786485
NVI: 100113939
CSOL: 105363277
MDL: 103578146
TCA: 664530
DPA: 109534435
ATD: 109599200
NVL: 108558089
BMOR: 733141
BMAN: 114249994
PMAC: 106708794
PRAP: 110995044
HAW: 110374195
PXY: 105387572
DNX: 107167267
AGS: 114131152
CLEC: 106661260
CEL: CELE_F32D8.6(sec-61.G)
CBR: CBG09730(Cbr-emo-1)
BMY: Bm1_05280
SHX: MS3_06517
EGL: EGR_03491
CPAP: 110820468
CIT: 102612236
CAM: 101503804
DOSA: Os02t0178400-01(Os02g0178400) Os06t0653900-01(Os06g0653900)
ATS: 109749393(LOC109749393) 109749441(LOC109749441)
EGU: 105039585
CRE: CHLREDRAFT_185246(SEC61G)
MNG: MNEG_8440
APRO: F751_1501
MIS: MICPUN_109616(SEC61g)
SCE: YDR086C(SSS1)
ERC: Ecym_7218
NCS: NCAS_0B04080(NCAS0B04080)
NDI: NDAI_0F02900(NDAI0F02900)
TPF: TPHA_0B03490(TPHA0B03490)
TBL: TBLA_0J00510(TBLA0J00510)
TDL: TDEL_0A01420(TDEL0A01420)
KAF: KAFR_0A02500(KAFR0A02500)
NCR: NCU04127
NTE: NEUTE1DRAFT93606(NEUTE1DRAFT_93606)
MGR: MGG_02742
SSCK: SPSK_09955
MAW: MAC_09226
MAJ: MAA_08509
CMT: CCM_07028
BFU: BCIN_01g01900(Bcsss1)
MBE: MBM_06289
ANI: AN4589.2
ANG: ANI_1_1570014(An01g11630)
PTE: PTT_13234
SPO: SPAC4G8.02c(sss1)
CNE: CNA00580
CNB: CNBA0560
TASA: A1Q1_05243
MRR: Moror_323
ABP: AGABI1DRAFT124441(AGABI1DRAFT_124441)
MGL: MGL_1800
MRT: MRET_2013
DDI: DDB_G0287777(sec61g)
DFA: DFA_10278(sec61g)
EHI: EHI_038990(7.t00045) EHI_048170(108.t00029)
PCB: PCHAS_030910(PC301670.00.0)
TAN: TA04175
TPV: TP03_0370
BBO: BBOV_IV002770(21.m03061)
CPV: cgd7_4210
MJA: MJ_0371
MMP: MMP1435
MMD: GYY_08010(secE)
MMAK: MMKA1_16590(secE)
MMAO: MMOS7_15420(secE)
MMAD: MMJJ_14040
MAE: Maeo_1011
MVO: Mvol_1485
MTH: MTH_1677
METC: MTCT_1530
MWO: MWSIV6_0215(secE)
METE: tca_01624(secE)
MST: Msp_1268
METB: AW729_09325(secE)
MRU: mru_0482(secE)
MSI: Msm_0625
MEB: Abm4_0254(secE)
MMIL: sm9_0345(secE)
MEYE: TL18_01500(secE)
MOL: YLM1_0156
METH: MBMB1_0446
MFC: BRM9_1812(secE)
MCUB: MCBB_0408
MFV: Mfer_0141
MKA: MK0822(sss1)
AFU: AF_0536
FPL: Ferp_1353
GAC: GACE_0219
GAH: GAH_00077
TAC: Ta1426
TVO: TVG1518472(TVG1518472)
PTO: PTO0446
FAI: FAD_1611
CDIV: CPM_0189
MER: MMINT_17390(secE)
MARC: AR505_1799
ABI: Aboo_0865
PFU: PF1989
PFI: PFC_08620(secE)
PAB: PAB3002
PYN: PNA2_0811
PYS: Py04_0061
PYC: TQ32_07065(secE)
TKO: TK1420
TON: TON_0177
TGA: TGAM_0484(secE)
TSI: TSIB_0380
THE: GQS_03735
THA: TAM4_941
THM: CL1_0398
TLT: OCC_02159(secE)
THS: TES1_0281
TNU: BD01_0047
TEU: TEU_05740(secE)
TGY: X802_06380(secE)
TPEP: A0127_08040(secE)
TGG: A3K92_07705(secE)
TCE: A3L02_09810(secE)
TBS: A3L01_02185(secE)
TSL: A3L11_06005(secE)
TTD: A3L14_03630(secE)
TPRF: A3L09_09775(secE)
TRL: A3L10_04340(secE)
TPAF: A3L08_04805(secE)
THY: A3L12_02005(secE)
PPAC: PAP_02235(secE)
MBAR: MSBR2_3139
MBAK: MSBR3_3134
MAC: MA_4272
MMA: MM_1009
MMAC: MSMAC_0296
METM: MSMTP_0327
MTHR: MSTHT_1594
MTHE: MSTHC_1695
MHOR: MSHOH_0390
MBU: Mbur_1943
MMH: Mmah_0179
MPY: Mpsy_1496(secE)
MTP: Mthe_0632
MCJ: MCON_1931(secE)
MHI: Mhar_2392
MHU: Mhun_0659
MLA: Mlab_1584
MEMA: MMAB1_0243
MPI: Mpet_2130
MBN: Mboo_2264
MPL: Mpal_0160
MPD: MCP_2135(secE)
MEZ: Mtc_2072(secE)
RCI: LRC29(secE)
HAL: VNG_0375G(secE)
HSL: OE_1558R(secE)
HHB: Hhub_1625(secE)
HALH: HTSR_1397(secE)
HHSR: HSR6_1469(secE)
HSU: HLASF_0671(secE)
HSF: HLASA_0667(secE)
HMA: rrnAC0700(secE)
HHI: HAH_1349(secE)
NPH: NP_0812A(secE)
NMO: Nmlp_1154(secE)
HUT: Huta_0894
HTI: HTIA_0753
HMU: Hmuk_2937
HALL: LC1Hm_2288(sss1)
HWA: HQ_1242A(secE)
HWC: Hqrw_1270(secE)
HVO: HVO_0718(secE)
HME: HFX_0677(secE)
HLA: Hlac_0900
HDF: AArcSl_1217(secE)
HTU: Htur_2642
NMG: Nmag_1140(secE)
NAT: NJ7G_1254
SALI: L593_03135(secE)
APE: APE_2176a(secE)
ACJ: ACAM_1366(secE)
IHO: Igni_1178
DKA: DKAM_1106
TAG: Tagg_0937
IAG: Igag_1416
HBU: Hbut_1603
ASC: ASAC_0947
ACIA: SE86_05020
NCT: NMSP_1338
NCV: NCAV_1548
BARC: AOA65_2183
BARB: AOA66_0696
CCAI: NAS2_1586
MARH: Mia14_0135
AGW: QT03_C0001G0503(secE)
 » show all
Reference
PMID:8945469
  Authors
Wiertz EJ, Tortorella D, Bogyo M, Yu J, Mothes W, Jones TR, Rapoport TA, Ploegh HL
  Title
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction.
  Journal
Nature 384:432-8 (1996)
DOI:10.1038/384432a0
  Sequence
[hsa:23480]
Reference
  Authors
Falcone D, Henderson MP, Nieuwland H, Coughlan CM, Brodsky JL, Andrews DW
  Title
Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence.
  Journal
Biochem J 436:291-303 (2011)
DOI:10.1042/BJ20101865
  Sequence
[sce:YDR086C]
Reference
  Authors
Rapoport TA
  Title
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
  Journal
Nature 450:663-9 (2007)
DOI:10.1038/nature06384
LinkDB

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