KEGG   ORTHOLOGY: K11006
Entry
K11006                      KO                                     

Name
stxA
Definition
shiga toxin subunit A
Pathway
ko02024  Quorum sensing
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
Module
M00363  EHEC pathogenicity signature, Shiga toxin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K11006  stxA; shiga toxin subunit A
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K11006  stxA; shiga toxin subunit A
   05131 Shigellosis
    K11006  stxA; shiga toxin subunit A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K11006  stxA; shiga toxin subunit A
Bacterial toxins [BR:ko02042]
 Type III toxins: Intracellular toxins
  Others
   Shiga toxin
    K11006  stxA; shiga toxin subunit A
Genes
ECE: Z1464(stx2A) Z3344(stx1A)
ECS: ECs1205 ECs2974
ECF: ECH74115_2906 ECH74115_3533
ETW: ECSP_2723(stx2A1) ECSP_3253(stx2A2)
ELX: CDCO157_1154 CDCO157_2739
EOI: ECO111_2430 ECO111_3361
EOJ: ECO26_1599
EOH: ECO103_2845 ECO103_5197
ECOO: ECRM13514_3145(stx2A)
ECOH: ECRM13516_2316(stx2A)
ESL: O3K_16135
ESO: O3O_09165
ESM: O3M_16110
SDY: SDY_1389(stxA)
VG: 1261950(stxA2) 1262249(stx2A) 13828571(stx2A) 14005228(F366_gp36) 1481747(stx1A) 1481767(stx2A) 22277199(PI30_gp34) 26228052(AS349_gp84) 2641645(stxA1) 26516284(stxA) 26516496(stx2A) 26519429(AU154_gp39) 26798065(AXI88_gp33) 4397483(stx2A) 6159405(stx2A) 6973079(YYZ_gp39) 6973138(Stx2-1717_gp41) 929695(stxA2e)
 » show all
Reference
  Authors
Muthing J, Schweppe CH, Karch H, Friedrich AW
  Title
Shiga toxins, glycosphingolipid diversity, and endothelial cell injury.
  Journal
Thromb Haemost 101:252-64 (2009)
DOI:10.1160/TH08-05-0317
Reference
  Authors
Asakura H, Makino S, Kobori H, Watarai M, Shirahata T, Ikeda T, Takeshi K
  Title
Phylogenetic diversity and similarity of active sites of Shiga toxin (stx) in Shiga toxin-producing Escherichia coli (STEC) isolates from humans and animals.
  Journal
Epidemiol Infect 127:27-36 (2001)
DOI:10.1017/S0950268801005635
  Sequence
[ece:Z1464 Z3344]
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