KEGG   ORTHOLOGY: K11155
Entry
K11155                      KO                                     

Name
DGAT1
Definition
diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76]
Pathway
ko00561  Glycerolipid metabolism
ko00830  Retinol metabolism
ko01100  Metabolic pathways
ko04975  Fat digestion and absorption
Module
M00089  Triacylglycerol biosynthesis
Disease
H01174  Congenital diarrhea
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    K11155  DGAT1; diacylglycerol O-acyltransferase 1
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K11155  DGAT1; diacylglycerol O-acyltransferase 1
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K11155  DGAT1; diacylglycerol O-acyltransferase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.20  diacylglycerol O-acyltransferase
     K11155  DGAT1; diacylglycerol O-acyltransferase 1
    2.3.1.75  long-chain-alcohol O-fatty-acyltransferase
     K11155  DGAT1; diacylglycerol O-acyltransferase 1
    2.3.1.76  retinol O-fatty-acyltransferase
     K11155  DGAT1; diacylglycerol O-acyltransferase 1
Other DBs
RN: R02251 R02366 R02367 R08381
GO: 0004144 0050252
Genes
HSA: 8694(DGAT1)
PTR: 464460(DGAT1)
PPS: 100994391(DGAT1)
GGO: 101142898(DGAT1)
PON: 100453587(DGAT1)
NLE: 100590733(DGAT1)
MCC: 701489(DGAT1)
MCF: 102121566(DGAT1)
CSAB: 103237618(DGAT1)
CATY: 105581243(DGAT1)
RRO: 104671680(DGAT1)
RBB: 108536546(DGAT1)
TFN: 117079312(DGAT1)
CJC: 100402659(DGAT1)
SBQ: 101041407(DGAT1)
MMUR: 105868898(DGAT1)
MMU: 13350(Dgat1)
MCAL: 110310326(Dgat1)
MPAH: 110334746(Dgat1)
RNO: 84497(Dgat1)
MCOC: 116074725(Dgat1)
MUN: 110562264(Dgat1)
CGE: 100755985(Dgat1)
PLEU: 114694176(Dgat1)
NGI: 103735255(Dgat1)
HGL: 101723650(Dgat1)
CCAN: 109691174(Dgat1)
OCU: 100350630(DGAT1)
TUP: 102474487(DGAT1)
CFA: 482093(DGAT1)
VVP: 112911178(DGAT1)
VLG: 121498689(DGAT1)
AML: 100479095(DGAT1)
UMR: 103656696(DGAT1)
UAH: 113247638(DGAT1)
ORO: 101366779(DGAT1)
ELK: 111146542
MPUF: 101693117(DGAT1)
EJU: 114201092(DGAT1)
FCA: 101101615(DGAT1)
PTG: 102952284(DGAT1)
PPAD: 109258372(DGAT1)
AJU: 106979135(DGAT1)
HHV: 120246564(DGAT1)
BTA: 282609(DGAT1)
BOM: 102277779(DGAT1)
BBUB: 102390126(DGAT1)
CHX: 100861225(DGAT1)
OAS: 100126245(DGAT1)
ODA: 120878731(DGAT1)
SSC: 397118(DGAT1)
CFR: 102515256(DGAT1)
CDK: 105104999(DGAT1)
BACU: 103001320(DGAT1)
LVE: 103073062(DGAT1)
OOR: 101275488(DGAT1)
DLE: 111165111(DGAT1)
PCAD: 102974279(DGAT1)
ECB: 100147359(DGAT1)
EPZ: 103540220(DGAT1)
EAI: 106841896(DGAT1)
MYB: 102263903(DGAT1)
MYD: 102769363(DGAT1)
MMYO: 118653153(DGAT1)
MNA: 107539955(DGAT1)
HAI: 109375066(DGAT1)
DRO: 112315624(DGAT1)
SHON: 118988846(DGAT1)
AJM: 119064708(DGAT1)
MMF: 118643309(DGAT1)
PALE: 102889573(DGAT1)
RAY: 107503468(DGAT1)
MJV: 108399471(DGAT1)
TMU: 101350605
MDO: 100018271(DGAT1)
SHR: 100924635(DGAT1)
PCW: 110214325(DGAT1)
OAA: 103166832(DGAT1)
FPG: 106112364(DGAT1)
FCH: 106631435(DGAT1)
AAM: 106485793 106487807(DGAT1)
ASN: 102375256(DGAT1)
AMJ: 102576196(DGAT1)
CPOO: 109310393(DGAT1)
PSS: 102448420(DGAT1)
CMY: 102930647 102932469(DGAT1)
CPIC: 101950960(DGAT1) 101951746
TST: 117871848(DGAT1) 117886576
CABI: 116827482 116828232(DGAT1)
ACS: 100551857(dgat1)
PVT: 110084814(DGAT1)
PBI: 103065772(DGAT1)
PMUR: 107300055(DGAT1)
PGUT: 117666944(DGAT1)
PMUA: 114600142(DGAT1)
ZVI: 118089698(DGAT1)
GJA: 107110672(DGAT1)
XLA: 100381012(dgat1.L)
XTR: 101730812(dgat1)
NPR: 108799410(DGAT1)
DRE: 325875(dgat1a) 436731(dgat1b)
IPU: 108257065(dgat1) 108267870
EEE: 113571147 113572060(dgat1)
TRU: 101072465 101079602(dgat1)
NCC: 104952233 104959283(dgat1)
ELY: 117261683 117263703(dgat1a) 117265232(dgat1b)
SLUC: 116040207 116047377(dgat1a) 116049462(dgat1b)
MSAM: 119893607 119897680(dgat1b) 119907078(dgat1a)
OAU: 116322502 116322667(dgat1a) 116331366(dgat1b)
OML: 112138961(dgat1a) 112143225(dgat1b)
XMA: 102220430 102225690(dgat1)
XCO: 114141802 114156467(dgat1)
XHE: 116717507 116731846(dgat1)
PRET: 103472475(dgat1) 103478641
KMR: 108241110(dgat1b) 108242037(dgat1a)
POV: 109633536 109638866(dgat1)
XGL: 120784326(dgat1b) 120786827(dgat1a) 120792803
ELS: 105018848 105022840(dgat1)
LOC: 102683351 102695280(dgat1)
LCM: 102349959(DGAT1) 102358735
CMK: 103183634(dgat1) 103185953
RTP: 109935410(dgat1) 109936697
BFO: 118417909
CIN: 100177672
SPU: 575003
APLC: 110982992
SKO: 100376218
DME: Dmel_CG31991(mdy)
DER: 6547631
DSE: 6614434
DSI: Dsimw501_GD24087(Dsim_GD24087)
DAN: 6498181
DSR: 110184937
DPE: 6589755
DMN: 108161944
DWI: 6643530
DAZ: 108611284
DNV: 115562354
DHE: 111601178
DVI: 6628957
MDE: 101894841
LCQ: 111682921
ACOZ: 120959456
AARA: 120900691
AAG: 5569069
AALB: 109418063
CPII: 120413867
AME: 552377
BIM: 100744121
BTER: 100646196
CCAL: 108630029
MGEN: 117224602
NMEA: 116424872
SOC: 105194711
MPHA: 105833565
ACEP: 105618616
PBAR: 105422883
VEM: 105564389
HST: 105182283
DQU: 106747317
CFO: 105253928
FEX: 115242388
PGC: 109852637
OBO: 105282087
PCF: 106788280
NVI: 100116518
CSOL: 105364922
MDL: 103568794
TCA: 664028
DPA: 109533688
ATD: 109602335
AGB: 108912570
NVL: 108568180
OTU: 111424823
BMOR: 101742497
BMAN: 114242959
MSEX: 115447123
PMAC: 106710683
PPOT: 106099440
PXU: 106127750
PRAP: 110991401
ZCE: 119830300
HAW: 110371905
TNL: 113506955
DCI: 103512092
CLEC: 106668819
NLU: 111054822
CSEC: 111872160
FCD: 110852290
PVM: 113829016
TUT: 107362581
PTEP: 107450283
SDM: 118196832
CEL: CELE_H19N07.4(mboa-2)
CBR: CBG23107
BMY: BM_BM12468(Bma-mboa-2)
TSP: Tsp_02502
PCAN: 112553384
BGT: 106051926
GAE: 121387998
CRG: 105331361
MYI: 110442476
PMAX: 117337851
OBI: 106869194
LAK: 106165236
EGL: EGR_02006
NVE: 5519524
EPA: 110238682
ATEN: 116299071
ADF: 107351603
AMIL: 114963989
PDAM: 113667048
SPIS: 111335241
DGT: 114516678
HMG: 101238034
ATH: AT2G19450(TAG1)
ALY: 9322105
CRB: 17891447
CPAP: 110817535
CIT: 102619099
PVY: 116113684
TCC: 18588364
GRA: 105793287
GAB: 108466843
DZI: 111286703
EGR: 104438076
GMX: 547982(DGAT) 548005(DGAT1A) 732606(DGAT1b)
LJA: Lj4g3v2172770.1(Lj4g3v2172770.1) Lj4g3v2172770.2(Lj4g3v2172770.2) Lj6g3v1226310.1(Lj6g3v1226310.1)
FVE: 101304125
RCN: 112187921
PPER: 18769247
PMUM: 103340712
PAVI: 110749273
PDUL: 117635026
ZJU: 107424129
MNT: 21409930
CSV: 101213517
CMO: 103498593
BHJ: 120079835
MCHA: 111021903
CMAX: 111493820
CMOS: 111450373
CPEP: 111805863
RCU: 8272569
JCU: 105637897(DGAT1)
QLO: 115976088
VVI: 100266364
VRI: 117925364
SIND: 105173637(DGAT1)
EGT: 105968927
LSV: 111892564
CSIN: 114276617
BVG: 104909051
SOE: 110797728
NNU: 104586668
MING: 122061644
NCOL: 116260096
DOSA: Os05t0196800-00(Os05g0196800) Os06t0563900-01(Os06g0563900)
ZMA: 100383910 103629820(DGAT1-2)
PEQ: 110022299
AOF: 109828648
ATR: 18443650
MNG: MNEG_1183
APRO: F751_6502
SLB: AWJ20_4739(ARE2)
NCR: NCU00035
NTE: NEUTE1DRAFT129602(NEUTE1DRAFT_129602)
MGR: MGG_05326
SSCK: SPSK_02335
MAW: MAC_07178
MAJ: MAA_07086
CMT: CCM_05029
MBE: MBM_00351
ANI: AN6159.2
ANG: ANI_1_1688104(An12g03600)
ABE: ARB_04951
TVE: TRV_06710
PTE: PTT_18543
DDI: DDB_G0271342(dgat1)
PCB: PCHAS_121690(PC301445.00.0)
TAN: TA19620
TPV: TP01_0247
BBO: BBOV_IV004970(23.m06462)
CPV: cgd2_1090
 » show all
Reference
  Authors
Shi Y, Cheng D
  Title
Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism.
  Journal
Am J Physiol Endocrinol Metab 297:E10-8 (2009)
DOI:10.1152/ajpendo.90949.2008
Reference
PMID:9756920
  Authors
Oelkers P, Behari A, Cromley D, Billheimer JT, Sturley SL
  Title
Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.
  Journal
J Biol Chem 273:26765-71 (1998)
DOI:10.1074/jbc.273.41.26765
  Sequence
[hsa:8694]
LinkDB

KEGG   ORTHOLOGY: K11160
Entry
K11160                      KO                                     

Name
DGAT2
Definition
diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75]
Pathway
ko00561  Glycerolipid metabolism
ko01100  Metabolic pathways
ko04975  Fat digestion and absorption
Module
M00089  Triacylglycerol biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    K11160  DGAT2; diacylglycerol O-acyltransferase 2
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K11160  DGAT2; diacylglycerol O-acyltransferase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.20  diacylglycerol O-acyltransferase
     K11160  DGAT2; diacylglycerol O-acyltransferase 2
    2.3.1.75  long-chain-alcohol O-fatty-acyltransferase
     K11160  DGAT2; diacylglycerol O-acyltransferase 2
Other DBs
RN: R02251
GO: 0004144
Genes
HSA: 84649(DGAT2)
PTR: 466714(DGAT2)
PPS: 100987880(DGAT2)
GGO: 101124779(DGAT2)
PON: 100442216(DGAT2)
NLE: 100596453(DGAT2)
MCC: 696549(DGAT2)
MCF: 102128601(DGAT2)
CSAB: 103248066(DGAT2)
CATY: 105578724(DGAT2)
RRO: 104665097(DGAT2)
RBB: 108545121(DGAT2)
TFN: 117079794(DGAT2)
CJC: 100414192(DGAT2)
SBQ: 101049433(DGAT2)
MMUR: 105860306(DGAT2)
MMU: 67800(Dgat2)
MCAL: 110298238(Dgat2)
MPAH: 110327696(Dgat2)
RNO: 252900(Dgat2)
MCOC: 116102617(Dgat2)
MUN: 110566217(Dgat2)
CGE: 100774981(Dgat2)
PLEU: 114698694(Dgat2)
NGI: 103743019(Dgat2)
HGL: 101698712(Dgat2)
CCAN: 109680743(Dgat2)
OCU: 100354838(DGAT2)
TUP: 102494423(DGAT2)
CFA: 485185(DGAT2)
VVP: 112928729(DGAT2)
VLG: 121476006(DGAT2)
AML: 100468811(DGAT2)
UMR: 103678126(DGAT2)
UAH: 113269335(DGAT2)
ORO: 101385232(DGAT2)
ELK: 111159441
MPUF: 101683621(DGAT2)
EJU: 114218654(DGAT2)
FCA: 101100329(DGAT2)
PTG: 102952153(DGAT2)
PPAD: 109267215(DGAT2)
AJU: 106976464(DGAT2)
HHV: 120229587(DGAT2)
BTA: 404129(DGAT2)
BOM: 102285649(DGAT2)
BIU: 109569733(DGAT2)
BBUB: 102404874(DGAT2)
CHX: 102174409(DGAT2)
OAS: 101110535(DGAT2)
ODA: 120876775(DGAT2)
SSC: 100294675(DGAT2) 110259135
CFR: 102504113(DGAT2)
CDK: 105097240(DGAT2)
BACU: 103018277(DGAT2)
LVE: 103075069(DGAT2)
OOR: 101283358(DGAT2)
DLE: 111184877(DGAT2)
PCAD: 102991226(DGAT2)
ECB: 100064387(DGAT2)
EPZ: 103548227(DGAT2)
EAI: 106840399(DGAT2)
MYB: 102249216 102261774(DGAT2)
MYD: 102753473(DGAT2)
MMYO: 118664624(DGAT2)
MNA: 107524453(DGAT2)
HAI: 109386362(DGAT2)
DRO: 112316013(DGAT2)
SHON: 118981593(DGAT2)
AJM: 119038935(DGAT2)
MMF: 118628088(DGAT2)
PALE: 102898739(DGAT2)
RAY: 107519183(DGAT2)
MJV: 108404469(DGAT2)
LAV: 100657191(DGAT2)
TMU: 101355455
MDO: 100011089(DGAT2)
SHR: 100914285(DGAT2)
PCW: 110210559(DGAT2)
OAA: 100088895(DGAT2)
GGA: 421309(DGAT2) 428693(AWAT1)
PCOC: 116229501 116237128(DGAT2)
MGP: 100540643 100545351(DGAT2)
CJO: 107308594(DGAT2) 107312638
NMEL: 110392121(DGAT2) 110403393
APLA: 101801215(DGAT2)
ACYG: 106042403(DGAT2) 106042952
TGU: 100220095(DGAT2) 100232309
LSR: 110471640(DGAT2) 110474359
SCAN: 103816429 103823769(DGAT2)
PMOA: 120502902(DGAT2) 120508757
GFR: 102035873(DGAT2) 102037230
FAB: 101810713(DGAT2) 101820931
PHI: 102100921 102107779(DGAT2)
PMAJ: 107204039 107211569(DGAT2)
CCAE: 111928595 111941011(DGAT2)
CCW: 104686963(DGAT2) 104691343
ETL: 114059609(DGAT2) 114065167
FPG: 101917877 101924658(DGAT2)
FCH: 102055207(DGAT2) 102057990
CLV: 102085339 102087439(DGAT2)
EGZ: 104124768(DGAT2) 104135988
NNI: 104012839 104022725(DGAT2)
ACUN: 113481155(DGAT2)
PADL: 103915186(DGAT2) 103919207
ASN: 102370139 102371123(DGAT2)
AMJ: 102557932(DGAT2) 102576534(AWAT2)
CPOO: 109306877(DGAT2) 109310891
GGN: 109300474 109303156(DGAT2)
PSS: 102449336 102453357(DGAT2)
CMY: 102929519 102930862(DGAT2)
CPIC: 101930999(DGAT2) 101950557
TST: 117871307(DGAT2) 117882695
ACS: 100552736(dgat2) 100555636
PVT: 110074308 110087798(DGAT2)
PBI: 103052621(DGAT2)
PMUR: 107299528
PGUT: 117679844(DGAT2)
PMUA: 114589371 114595553(DGAT2)
ZVI: 118084502 118085303(DGAT2)
GJA: 107110553 107112091(DGAT2)
XLA: 100126612(awat1.L) 100127341(awat1.S) 108698316(dgat2l6.L) 108710042(dgat2.S) 108710383(mogat3.L) 398800(dgat2.L)
XTR: 100127622(awat1) 100127752(dgat2l6) 100491581(mogat3) 395003(dgat2)
DRE: 494083(mogat3b) 565316(dgat2)
SGH: 107578632 107588782(dgat2) 107596103 107599198(mogat3)
IPU: 100528806(dgat2) 108259936
PHYP: 113524198(dgat2) 113531204
EEE: 113589528(dgat2) 113590600
TRU: 101071223 101079383(dgat2)
LCO: 104931787(dgat2) 104937288
NCC: 104942132(dgat2)
ELY: 117246453(dgat2) 117264098(mogat3b)
PLEP: 121952909(dgat2) 121953073(mogat3b)
SLUC: 116058252(dgat2) 116064928(mogat3b)
GAT: 120821650(mogat3b) 120822783(dgat2)
MSAM: 119895050(mogat3b) 119895214(dgat2)
MZE: 101484727 101485008(dgat2)
ONL: 100707401 100709028(dgat2)
OAU: 116320588(dgat2) 116330302(mogat3b)
OLA: 101166733 101175675(dgat2)
OML: 112142473(mogat3b) 112142623(dgat2)
XMA: 102219836(dgat2) 102228247
XCO: 114152662 114153067(dgat2)
XHE: 116728361(dgat2) 116728435
PRET: 103475773 103476122(dgat2)
CVG: 107097472(dgat2) 107099793
NFU: 107386011(dgat2) 107386510
KMR: 108244705(dgat2) 108248268(mogat3b)
ALIM: 106517203(dgat2) 106535072
AOCE: 111577661 111587031(dgat2)
CSEM: 103394818(dgat2) 103395417
POV: 109628346 109628731(dgat2)
LCF: 108893507 108893792(dgat2)
SDU: 111222364(dgat2) 111234506
SLAL: 111653950 111663527(dgat2)
XGL: 120802291(dgat2) 120802722(mogat3b)
HCQ: 109531183(dgat2)
BPEC: 110158360 110165125(dgat2)
MALB: 109959536 109972857(dgat2)
ELS: 105005790 105010982(dgat2)
SFM: 108936020(dgat2)
PKI: 111858447(dgat2)
LOC: 102684783(dgat2)
LCM: 102351093(DGAT2) 102359647(MOGAT3) 102360601
CMK: 103188598(dgat2) 103190916
EAF: 111709831
ATEN: 116293380
 » show all
Reference
  Authors
Shi Y, Cheng D
  Title
Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism.
  Journal
Am J Physiol Endocrinol Metab 297:E10-8 (2009)
DOI:10.1152/ajpendo.90949.2008
Reference
  Authors
Cases S, Stone SJ, Zhou P, Yen E, Tow B, Lardizabal KD, Voelker T, Farese RV Jr
  Title
Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.
  Journal
J Biol Chem 276:38870-6 (2001)
DOI:10.1074/jbc.M106219200
  Sequence
[hsa:84649]
LinkDB

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